Udiliv 600 Tablet: Complete Guide to Uses, Dosage, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain that does not go away
- Vomiting blood or material that looks like coffee grounds
- Black, tarry stools or blood in stool
- Yellowing of the skin or eyes (jaundice)
- Dark urine or pale stools
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe diarrhea with signs of dehydration (dizziness, reduced urination)
- Sudden weight gain or swelling in the legs
- Confusion or extreme fatigue
If experiencing severe symptoms, call emergency services immediately.
What is ursokem od 600mg tablet used for?
This medicine contains Ursodeoxycholic Acid 600 mg, used to dissolve cholesterol gallstones and treat primary biliary cholangitis. It works by reducing cholesterol in bile and protecting liver cells. Take it exactly as prescribed, usually with meals, and attend regular check-ups.
- Generic Name: Ursodeoxycholic Acid (600mg)
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ursokem od 600mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा अर्सोडीऑक्सीकोलिक एसिड 600 मिलीग्राम की एक गोली है, जिसका उपयोग मुख्य रूप से पित्ताशय की पथरी (कोलेस्ट्रॉल गॉलस्टोन) को घोलने और प्राइमरी बिलियरी कोलैंगाइटिस नामक लीवर रोग के इलाज के लिए किया जाता है। यह दवा लीवर में कोलेस्ट्रॉल की मात्रा को कम करती है और पित्त के प्रवाह को सुधारती है, जिससे पथरी धीरे-धीरे घुल जाती है और लीवर की कोशिकाएं सुरक्षित रहती हैं। यह गर्भावस्था में होने वाली पित्त रुकावट (इंट्राहेपेटिक कोलेस्टेसिस) और सिस्टिक फाइब्रोसिस से जुड़े लीवर रोग में भी उपयोगी हो सकती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए और इसका सेवन डॉक्टर के निर्देशानुसार ही करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट में असहजता और अपच शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। यदि दस्त गंभीर या लगातार बने रहें तो डॉक्टर से संपर्क करें। कभी-कभी सिरदर्द, चक्कर आना, पीठ दर्द और त्वचा पर दाने भी हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको तेज पेट दर्द, उल्टी में खून, मल में खून, त्वचा या आंखों का पीला पड़ना, गहरे रंग का पेशाब, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से खुराक न बदलें और न ही दवा लेना बंद करें। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। इसे भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। यदि आप कोई खुराक भूल जाएं तो याद आते ही ले लें, लेकिन यदि अगली खुराक का समय नजदीक हो तो भूली हुई खुराक छोड़ दें और दोहरी खुराक न लें। इलाज के दौरान शराब न पिएं। नियमित रूप से लीवर फंक्शन टेस्ट और अल्ट्रासाउंड करवाते रहें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। इस दवा को कमरे के तापमान पर, नमी और धूप से दूर, बच्चों की पहुंच से बाहर रखें।
💊 ursokem od 600mg tablet Uses & Benefits
[{"condition":"Cholesterol gallstones dissolution","description":"Used to dissolve small, non-calcified cholesterol gallstones in patients who cannot undergo surgery or who have contraindications to cholecystectomy.","evidence":"Well-established"},{"condition":"Primary biliary cholangitis","description":"First-line therapy to slow disease progression and improve liver biochemistry in patients with primary biliary cholangitis.","evidence":"Well-established"},{"condition":"Intrahepatic cholestasis of pregnancy","description":"Used to relieve itching and improve liver function in pregnant women with intrahepatic cholestasis of pregnancy.","evidence":"Moderate"},{"condition":"Cystic fibrosis-related liver disease","description":"May be used to improve bile flow and liver function in patients with cystic fibrosis who develop liver disease.","evidence":"Limited"},{"condition":"Biliary dyskinesia","description":"Sometimes used to improve bile flow in patients with functional gallbladder disorder, though evidence is limited.","evidence":"Limited"}]
Off-label uses: [{"condition":"Non-alcoholic steatohepatitis","description":"Occasionally prescribed off-label to improve liver enzymes in patients with non-alcoholic steatohepatitis, but evidence is not strong.","evidence":"Limited"},{"condition":"Liver transplant rejection prophylaxis","description":"Sometimes used off-label in combination with other immunosuppressants to prevent liver transplant rejection.","evidence":"Limited"}]
Primary treatment for: Cholesterol gallstones and primary biliary cholangitis
Also treats: Intrahepatic cholestasis of pregnancy, Cystic fibrosis-related liver disease, Biliary dyskinesia, Non-alcoholic steatohepatitis (off-label)
📋 Drug Information
| Generic Name(s) | Ursodeoxycholic Acid (600mg) |
| Brand Name | ursokem od 600mg tablet |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Hepatoprotectives |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in their original container, tightly closed, away from moisture and direct sunlight. Do not refrigerate unless specified by the manufacturer. Keep out of reach of children and pets. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by replacing toxic bile acids in the liver and bile. Ursodeoxycholic Acid is a hydrophilic bile acid that reduces the cholesterol content of bile by inhibiting cholesterol absorption in the intestine and decreasing cholesterol secretion into bile. This helps dissolve cholesterol gallstones over time. In liver diseases, it protects liver cells from the toxic effects of hydrophobic bile acids by competing for absorption in the ileum and by stabilizing cell membranes. It also stimulates bile flow, which helps flush out retained bile acids and reduces cholestasis. Additionally, it has immunomodulatory effects that may help reduce liver inflammation in conditions like primary biliary cholangitis.
Mechanism Steps
💡 How to Take ursokem od 600mg tablet
Strength: Ursodeoxycholic Acid 600 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for gallstone dissolution is 8-10 mg per kg of body weight per day, divided into 2-3 doses. For primary biliary cholangitis, the typical dose is 13-15 mg per kg per day, divided into 2-4 doses. The 600 mg tablet is often prescribed as one tablet two or three times daily, depending on the condition and body weight. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients based on age alone. However, because elderly patients may have reduced liver or kidney function, the dose should be individualized by a clinician. Regular monitoring is advised. |
| Renal Impairment | No dose adjustment is required for patients with renal impairment. However, caution is advised in severe renal disease, and monitoring is recommended. |
| Hepatic Impairment | No specific dose adjustment is recommended for mild to moderate hepatic impairment. In severe hepatic impairment, the medicine should be used with caution and under close medical supervision. Dose individualization by a clinician is necessary. |
| Maximum Daily Dose | The maximum recommended daily dose is 15 mg per kg of body weight, but this should not exceed the dose prescribed by your doctor. For the 600 mg tablet, the maximum daily dose is usually 1800 mg (three tablets) unless otherwise directed by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ursokem od 600mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aluminum-based antacids | Major | |
| Cholestyramine | Major | |
| Cyclosporine | Major | |
| Oral contraceptives | Moderate | |
| Clofibrate | Moderate | |
| Ciprofloxacin | Moderate | |
| Nitrendipine | Moderate | |
| Dapsone | Moderate | |
| Rosuvastatin | Moderate | |
| Activated charcoal | Minor |
🚨 Major Interactions
- Aluminum-based antacids
- Cholestyramine, colestipol, colesevelam
- Oral contraceptives containing estrogen
- Clofibrate
- Cyclosporine
⚡ Moderate Interactions
- Ciprofloxacin
- Nitrendipine
- Dapsone
- Rosuvastatin
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine, as both alcohol and Ursodeoxycholic Acid are metabolized by the liver. Alcohol can increase the risk of liver damage and may worsen the underlying liver condition being treated. If you have a history of alcohol use, discuss with your doctor before taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to Ursodeoxycholic Acid or any component of the tablet.","Acute inflammation of the gallbladder or bile ducts (cholangitis, cholecystitis).","Complete obstruction of the bile duct.","Calcified cholesterol gallstones that do not dissolve.","Frequent episodes of biliary colic.","Severe liver impairment with hepatic encephalopathy.","Inability to visualize the gallbladder on oral cholecystography."]
⚠️ Warnings & Precautions
["Take this medicine exactly as prescribed. Do not exceed the recommended dose.","Inform your doctor if you have liver disease, kidney disease, or heart disease.","Avoid alcohol while taking this medicine.","Tell your doctor about all other medicines, supplements, and herbal products you are taking.","If you are pregnant or breastfeeding, consult your doctor before use.","Regular monitoring of liver function and gallstone size is necessary.","If you experience severe diarrhea, stop the medicine and contact your doctor.","Do not use this medicine for gallstones that are calcified or larger than 15 mm, as it may not be effective.","This medicine may take weeks to months to show its full effect. Be patient and follow up regularly."]
🤱 Lactation Safety
Ursodeoxycholic Acid is excreted in breast milk in small amounts. It is generally considered safe during breastfeeding, but you should consult your doctor before using it while nursing. Monitor the infant for any unusual symptoms such as diarrhea or poor feeding.
💊 Overdose Management
Overdose with Ursodeoxycholic Acid is unlikely to cause serious harm. Symptoms of overdose may include severe diarrhea, nausea, and abdominal pain. If you suspect an overdose, contact your doctor or a poison control center immediately. Treatment is supportive and symptomatic. There is no specific antidote. In case of accidental ingestion of a large amount, seek medical attention.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Swallow the tablet whole with a glass of water; do not crush or chew it unless your doctor instructs otherwise. You can take it with or without food, but taking it with meals may help reduce stomach upset. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Keep all appointments for blood tests and imaging studies, as your doctor needs to monitor your liver function and the size of your gallstones. Avoid alcohol while taking this medicine, as it can increase the risk of liver problems. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also, tell your doctor about all other medicines, supplements, and herbal products you are taking, as some may interact with this medicine. Store the tablets at room temperature, away from moisture and direct sunlight, and keep them out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, particularly diarrhea and dizziness. Dose individualization by a clinician is recommended. Regular monitoring of liver and kidney function is advised. Falls risk should be assessed if dizziness occurs.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is considered safe for use during pregnancy when prescribed for conditions like intrahepatic cholestasis of pregnancy. However, the dose and duration should be determined by your doctor. If you become pregnant while taking this medicine, inform your doctor immediately.
🏥 Post-Surgery Considerations
If you have undergone gallbladder removal surgery, this medicine may no longer be needed for gallstone dissolution. However, it may still be prescribed for other liver conditions. Follow your doctor's advice regarding continuation after surgery. If you have any surgery planned, inform your surgeon about this medicine.
🦷 Dental Procedures
There are no specific precautions for dental procedures while taking this medicine. However, inform your dentist about all medicines you are taking. If you are due for a dental procedure, continue taking this medicine as prescribed unless your doctor advises otherwise.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Exercise is generally safe and encouraged, but listen to your body and do not overexert yourself. If you have gallstone pain, avoid sudden jerky movements that may aggravate pain.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to significantly impact your daily work or life. Some people may experience mild diarrhea or nausea initially, which can be managed by taking the tablet with food. If you experience dizziness, avoid driving or operating machinery until it resolves. Most patients can continue their normal activities. However, if you have severe symptoms like abdominal pain, you may need to rest and consult your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will determine when it is appropriate to stop based on your condition, response to treatment, and monitoring results. For gallstone dissolution, treatment may be stopped once the stones have dissolved, but they may recur if the underlying risk factors persist. For chronic liver disease, treatment is often long-term. If you experience serious side effects, your doctor may advise stopping the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored by a doctor. It may be continued for years in conditions like primary biliary cholangitis. Regular monitoring of liver function tests and gallstone size is necessary. In rare cases, prolonged use may lead to calcification of gallstones, making them resistant to dissolution. Some patients may experience persistent diarrhea. Long-term use does not appear to cause kidney or heart damage. Always follow your doctor's advice regarding duration and monitoring.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Removal of the gallbladder is the definitive treatment for symptomatic gallstones and prevents recurrence.
Evidence: Well-establishedA non-invasive procedure that uses shock waves to break up gallstones, but it is only suitable for certain patients.
Evidence: ModerateA low-fat, high-fiber diet can help prevent gallstone formation and reduce symptoms.
Evidence: ModerateGeneric versions of the same active ingredient are available and equally effective.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions or timing considerations with this medicine. However, if you have liver disease, discuss with your doctor about appropriate vaccinations, such as hepatitis A and B vaccines, as they may be recommended.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a doctor's note explaining the medical condition and the need for the medicine. Keep the tablets in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and avoid leaving them in a hot car or checked baggage. If you are crossing time zones, continue taking the medicine at your usual intervals; you may need to adjust the timing gradually. Check the customs regulations of your destination country regarding prescription medicines. Always carry enough supply for your entire trip plus extra in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: For gallstone dissolution, it may take 6 months to 2 years of continuous treatment. For relief of cholestatic itching, improvement may be seen within a few weeks. For primary biliary cholangitis, liver enzyme improvement may take several months.
A: Yes, you can take it with or without food, but taking it with meals is recommended to improve absorption and reduce stomach upset.
A: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: It is best to avoid alcohol while taking this medicine, as alcohol can increase the risk of liver damage and may worsen your condition.
A: No, do not stop without consulting your doctor. Stopping early may cause gallstones to recur or your liver condition to worsen. Your doctor will decide when it is safe to stop.
A: Weight gain is not a common side effect of this medicine. However, if you notice any unusual weight changes, consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for ursokem od 600mg tablet
View AllAlternative brands with exact same active ingredient:
-
ureo 600mg tabletEveson Pharma ₹327.00 32.1% COSTLIER
-
hepalife 600 cr tabletGoddres Pharmaceuticals Pvt Ltd ₹333.33 34.6% COSTLIER
-
actibile 600 sr tabletZydus Cadila ₹421.00 70% COSTLIER
-
urmocol sr 600 tabletAptroshine Pharmaceuticals ₹521.50 110.6% COSTLIER
-
ursolid 600mg tablet srLeeford Healthcare Ltd ₹560.00 126.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Udiliv 600 can dissolve all types of gallstones.
Fact: It is only effective for cholesterol gallstones that are small and non-calcified. It does not work for pigment stones or calcified stones. - Myth: Udiliv 600 provides immediate pain relief.
Fact: It is not a painkiller. It works gradually over weeks to months to dissolve stones and improve liver function. - Myth: You can stop taking Udiliv 600 once you feel better.
Fact: You should not stop without consulting your doctor. Stopping early may cause stones to recur or liver condition to worsen. - Myth: Udiliv 600 is safe to take without a prescription.
Fact: It is a prescription medicine and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Ursodeoxycholic Acid 600 mg tablet (various manufacturers)
Brand Alternatives
- Udiliv 600 tablet