Polycain Oral Gel (magaldrate + Simethicone): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe or persistent abdominal pain
- Difficulty swallowing or food getting stuck
- Unexplained weight loss
- Persistent vomiting or inability to keep fluids down
- Chest pain or difficulty breathing
- Yellowing of the skin or eyes
- Decreased urine output or swelling of the legs
If experiencing severe symptoms, call emergency services immediately.
What is ulticid 800 mg/125 mg oral gel used for?
This medicine is an oral antacid gel containing magaldrate 800 mg and simethicone 125 mg. It neutralises excess stomach acid and helps relieve trapped gas, providing short-term relief from heartburn, indigestion, bloating and belching. It should be taken as directed, usually after meals or at bedtime, and should not be used for more than two weeks without medical advice.
- Generic Name: Magaldrate (800mg) + Simethicone (125mg)
- Manufacturer: Unimarck Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ulticid 800 mg/125 mg oral gel के बारे में (Hindi Summary)
उपयोग: यह दवा मैगल्ड्रेट 800 मिलीग्राम और सिमेथिकोन 125 मिलीग्राम का मिश्रण है, जो जमैकन स्ट्रॉबेरी स्वाद वाले ओरल जेल के रूप में आती है। यह पेट की अतिरिक्त एसिडिटी को कम करती है और पेट में फंसी गैस को बाहर निकालने में मदद करती है। इसका उपयोग सीने में जलन, एसिडिटी, अपच, पेट में गैस, पेट फूलना और डकार जैसी समस्याओं में राहत के लिए किया जाता है। यह दवा खाने के बाद या रात में सोने से पहले ली जा सकती है। यह केवल अस्थायी राहत देती है और लंबे समय तक बिना डॉक्टर की सलाह के नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा को अधिकतर लोग अच्छी तरह सहन करते हैं क्योंकि यह पेट में ही काम करती है। कुछ लोगों को दस्त, कब्ज, चॉकी स्वाद, जी मिचलाना, पेट में भरा-भरा महसूस होना या डकार जैसी हल्की समस्याएं हो सकती हैं। ये आमतौर पर हल्की और अस्थायी होती हैं। गुर्दे की बीमारी वाले लोगों में लंबे समय तक या अधिक मात्रा में लेने पर मैग्नीशियम या एल्युमिनियम का स्तर बढ़ सकता है, जिससे कमजोरी, भ्रम, धड़कन धीमी होना या सांस लेने में तकलीफ हो सकती है। ऐसी स्थिति में तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर या फार्मासिस्ट की सलाह के अनुसार ही लें और बताई गई मात्रा से अधिक न लें। अगर यह सस्पेंशन है तो हर बार लेने से पहले अच्छी तरह हिलाएं और दवा के साथ दी गई चम्मच या कप से ही मात्रा नापें। इस दवा और अन्य मुँह से ली जाने वाली दवाओं के बीच कम से कम दो घंटे का अंतर रखें, क्योंकि यह कई दवाओं के अवशोषण को कम कर सकती है। बिना डॉक्टर की सलाह के दो हफ्ते से ज्यादा इसका इस्तेमाल न करें। गुर्दे की बीमारी, हृदय रोग या मैग्नीशियम-प्रतिबंधित आहार लेने वाले लोग इसे डॉक्टर की देखरेख में ही लें। गर्भवती या स्तनपान कराने वाली महिलाएं उपयोग से पहले डॉक्टर से सलाह लें।
💊 ulticid 800 mg/125 mg oral gel Uses & Benefits
[{"condition":"Heartburn and acid indigestion","description":"This medicine neutralises excess stomach acid and provides rapid, short-term relief from burning discomfort behind the breastbone and sour taste in the mouth.","evidence":"Well-established"},{"condition":"Gastro-oesophageal reflux disease (symptomatic relief)","description":"Used as an add-on or as-needed treatment to reduce acid exposure in the oesophagus and relieve reflux symptoms such as regurgitation and burning.","evidence":"Well-established"},{"condition":"Gastritis and dyspepsia","description":"Helps relieve upper abdominal discomfort, fullness and burning associated with inflammation of the stomach lining or functional indigestion.","evidence":"Well-established"},{"condition":"Peptic ulcer disease (adjunctive symptom relief)","description":"Provides symptomatic relief of ulcer pain while definitive acid-suppressing therapy is being taken, but it does not heal ulcers on its own.","evidence":"Established as adjunctive therapy"},{"condition":"Flatulence, bloating and belching","description":"The simethicone component helps disperse trapped gas bubbles in the gastrointestinal tract, reducing abdominal bloating and discomfort.","evidence":"Well-established for symptom relief"},{"condition":"Gastric discomfort due to dietary indiscretion","description":"Occasionally used after heavy, spicy or fatty meals to relieve temporary acid-related stomach upset.","evidence":"Common clinical practice"}]
Off-label uses: [{"condition":"Prevention of stress-related mucosal bleeding","description":"Sometimes used in critically ill patients as a local antacid when acid suppression is needed, but this is not a standard approved use and should only be done under specialist supervision.","evidence":"Limited"},{"condition":"Contrast-induced nephropathy prevention","description":"Not established from the available information.","evidence":"Not established from the available information."}]
Primary treatment for: Acid-related gastrointestinal disorders such as heartburn, acid indigestion and gastro-oesophageal reflux.
Also treats: Gastritis, Dyspepsia, Peptic ulcer disease (symptomatic relief), Flatulence and bloating, Hiatus hernia with reflux symptoms
📋 Drug Information
| Generic Name(s) | Magaldrate (800mg) + Simethicone (125mg) |
| Brand Name | ulticid 800 mg/125 mg oral gel |
| Manufacturer | Unimarck Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature below 30°C in a dry place, protected from direct sunlight and moisture. Keep the bottle tightly closed and do not freeze unless the label specifically allows it. |
| Shelf Life | Refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary local mechanisms in the stomach. Magaldrate is a complex of aluminium hydroxide and magnesium hydroxide that reacts with gastric hydrochloric acid to form water and neutral salts, raising gastric pH and reducing the irritant effect of acid on the stomach and oesophagus. Because it is a balanced complex, it tends to cause less constipation or diarrhoea than equivalent doses of aluminium or magnesium salts used alone. Simethicone is a surface-active silicone polymer that reduces the surface tension of gas bubbles in the gastrointestinal tract, causing small bubbles to coalesce into larger ones that are easier to expel by belching or passing flatus. Neither component is intended to be absorbed systemically in a meaningful way, so the effect is confined largely to the gut lumen.
Mechanism Steps
💡 How to Take ulticid 800 mg/125 mg oral gel
Strength: Oral gel containing magaldrate 800 mg and simethicone 125 mg per measured dose, in a Jamaican strawberry flavour.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one to two teaspoonfuls or the equivalent measured dose of the oral gel taken after meals and at bedtime, or as needed for symptom relief. The exact dose and frequency depend on the severity of symptoms, the underlying condition and the advice of your doctor or pharmacist. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the maximum dose stated on the label, and do not use for more than two weeks without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults may use this medicine at the standard adult dose, but they are more likely to have reduced kidney function and to take multiple medicines. Dose must be individualized by a qualified clinician based on kidney function, other medicines and overall health. Prolonged use should be avoided unless advised by a doctor. |
| Renal Impairment | This medicine should be used with caution in people with reduced kidney function because aluminium and magnesium can accumulate. In severe kidney impairment it is usually avoided. Dose must be individualized by a qualified clinician based on renal function and clinical need. |
| Hepatic Impairment | No specific dose adjustment is usually required in liver disease because this medicine is not significantly metabolised by the liver. However, dose must be individualized by a qualified clinician based on the overall clinical situation. |
| Maximum Daily Dose | Do not exceed the maximum daily dose stated on the product label or advised by your doctor or pharmacist. Prolonged use at high doses should be avoided unless under medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ulticid 800 mg/125 mg oral gel
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Tetracycline | Major | |
| Ciprofloxacin | Major | |
| Levothyroxine | Major | |
| Iron salts | Major | |
| Alendronate | Moderate | |
| Ketoconazole | Moderate | |
| Digoxin | Moderate | |
| Prednisolone | Moderate | |
| Paracetamol | Minor | |
| Aspirin | Minor |
🚨 Major Interactions
- Tetracycline and doxycycline antibiotics
- Fluoroquinolone antibiotics such as ciprofloxacin and levofloxacin
- Iron salts
- Thyroid hormones such as levothyroxine
- Certain HIV medicines
⚡ Moderate Interactions
- Bisphosphonates such as alendronate
- Ketoconazole and itraconazole
- Some heart medicines such as digoxin
- Corticosteroids such as prednisolone
🍷 Alcohol Interaction
Alcohol can increase stomach acid production and irritate the stomach lining, which may make heartburn and gastritis worse and reduce the benefit of this medicine. It is advisable to avoid or limit alcohol while you are being treated for acid-related symptoms.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to magaldrate, aluminium, magnesium or simethicone","Severe kidney impairment or kidney failure","Suspected or confirmed gastrointestinal obstruction or perforation","Severe abdominal pain of unknown cause","Patients on a magnesium-restricted or aluminium-restricted diet","Severe dehydration or electrolyte disturbance","Children below the age recommended by the manufacturer unless advised by a doctor"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose or duration of use without medical advice.","Use with caution in elderly patients and in those with kidney, heart or liver disease.","Separate this medicine from other oral medicines by at least two hours to avoid absorption problems.","Do not use this medicine to treat unexplained weight loss, difficulty swallowing, persistent vomiting, black stools or blood in vomit.","Prolonged use can cause electrolyte disturbances and mineral accumulation, especially in kidney impairment.","Consult a doctor before use in pregnancy or breastfeeding.","Keep out of reach of children.","If symptoms persist beyond two weeks, seek medical evaluation."]
🤱 Lactation Safety
Magaldrate and simethicone are minimally absorbed, so the amount passing into breast milk is expected to be very small. Short-term use as directed is generally considered compatible with breastfeeding, but a doctor or pharmacist should be consulted before regular use.
💊 Overdose Management
Overdose with this medicine is uncommon because it acts locally, but large amounts can cause diarrhoea, abdominal pain, nausea, vomiting and electrolyte imbalance. In severe cases, especially in people with kidney disease, hypermagnesaemia or aluminium toxicity can occur. Treatment is supportive and may include stopping the medicine, monitoring electrolytes and kidney function, and giving intravenous fluids if needed. Contact a doctor or poison control centre immediately if a large overdose is suspected.
⏰ Missed Dose
This medicine is usually taken as needed for symptom relief rather than on a strict schedule. If you are taking it regularly and miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as directed by your doctor or pharmacist and do not exceed the recommended dose. Shake the bottle well before each use if it is a suspension, and measure the dose with the supplied spoon or cup rather than a household spoon. Maintain a gap of at least two hours between this medicine and other oral medicines, because antacids can reduce the absorption of many drugs. Avoid taking it at the same time as tetracycline or doxycycline antibiotics, iron tablets, thyroid medicines, certain heart medicines, HIV medicines or osteoporosis drugs. Do not use this medicine for more than two weeks without medical advice, and do not use it to treat unexplained weight loss, difficulty swallowing, persistent vomiting, black stools or blood in vomit. People with kidney disease, heart failure, low phosphate levels or a magnesium-restricted diet should only use this medicine under medical supervision. Pregnant or breastfeeding women should check with a doctor before use. Keep this medicine out of the reach of children and store it as directed on the label.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to have reduced kidney function and to take multiple medicines. This medicine should be used with caution, at the lowest effective dose, and for the shortest necessary duration. Regular review of kidney function and electrolytes may be needed with prolonged use.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. Short-term use of aluminium and magnesium antacids may be acceptable, but the need for treatment and the choice of medicine should be discussed with a healthcare professional.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if your surgeon or doctor advises it. Some surgeries may require avoiding oral intake or specific medicines for a period. Always inform your surgical team about all medicines you are taking.
🦷 Dental Procedures
This medicine does not usually interfere with dental procedures. However, inform your dentist about all medicines you take, especially if you are having surgery or are taking other drugs that may interact with antacids.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild to moderate exercise is generally safe while taking this medicine. However, vigorous exercise or bending immediately after meals can worsen reflux and heartburn. Wait at least one to two hours after eating before doing strenuous activity, and avoid exercises that increase abdominal pressure if you have significant reflux.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to work or drive. It does not usually cause drowsiness or impair concentration. However, if you feel dizzy, weak or unwell for any reason, avoid driving or operating heavy machinery until you feel better.
🛑 When to Stop This Medicine
Stop this medicine and consult a doctor if your symptoms do not improve within two weeks, if they get worse, or if you develop red-flag symptoms such as black stools, vomiting blood, difficulty swallowing, severe abdominal pain or unexplained weight loss. Do not stop any other prescribed medicine without your doctor's advice.
📅 Long-Term Use Effects
Long-term use of this medicine is generally not recommended without medical supervision. Prolonged use can lead to accumulation of aluminium and magnesium, especially in people with kidney disease, and may cause electrolyte disturbances such as low phosphate levels. It can also mask more serious underlying conditions such as ulcers or stomach cancer. If you need acid relief for more than two weeks, your doctor should review your symptoms and consider other treatments.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Smaller meals, avoiding trigger foods, weight management and not lying down soon after eating can reduce acid symptoms.
Evidence: Well-establishedFor frequent or severe reflux, doctors may prescribe acid-suppressing medicines instead of or in addition to antacids.
Evidence: Well-establishedThese reduce acid production and may be used when antacids alone are not enough.
Evidence: Well-establishedStress can worsen indigestion and reflux; relaxation methods may help as part of overall management.
Evidence: Supportive💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known vaccine interactions with this medicine. You can receive routine vaccinations while taking it unless your doctor advises otherwise.
📦 Storage Guide
✅ DO
Store at room temperature below 30°C in a dry place
❌ DON'T
Do not freeze unless the label specifically allows it
✅ DO
Keep the bottle tightly closed and upright
❌ DON'T
Do not leave the cap loose or store the bottle upside down
✅ DO
Keep away from direct sunlight and heat
❌ DON'T
Do not store near a stove, radiator or in a hot car
✅ DO
Keep out of reach of children
❌ DON'T
Do not transfer the medicine to an unlabelled container
✈️ Traveling with This Medicine
Carry this medicine in its original labelled container with the prescription or a copy of the prescription if it was prescribed. Keep it in your hand luggage if you need it during the journey, and store it away from direct sunlight and heat. If you are travelling across time zones and take it on a regular schedule, adjust the timing gradually according to your doctor's advice. Check the customs rules of your destination for carrying liquid medicines, and carry only the amount you need for the trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving heartburn and acid symptoms within a few minutes of taking it, because it acts directly in the stomach.
A: The effect generally lasts for about 30 to 60 minutes after a dose, depending on how much food is in the stomach.
A: It can be taken as needed for short periods, but daily use for more than two weeks should be discussed with a doctor.
A: Yes, but you should keep a gap of at least two hours between this medicine and other oral medicines to avoid absorption problems.
A: Short-term use may be acceptable, but you should consult your doctor or pharmacist before taking it during pregnancy.
A: If you are taking it regularly, take the missed dose as soon as you remember unless it is almost time for the next dose. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for ulticid 800 mg/125 mg oral gel
View AllAlternative brands with exact same active ingredient:
-
polycain oral gelSomatico Pharmacal Pvt Ltd ₹89.06 28.9% COSTLIER
-
polycain oral gel jamaican strawberrySomatico Pharmacal Pvt Ltd ₹199.00 188% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure ulcers permanently.
Fact: This medicine only relieves symptoms by neutralising acid. It does not eradicate Helicobacter pylori or heal ulcers on its own. Ulcers need proper medical treatment. - Myth: More antacid means faster relief.
Fact: Taking more than the recommended dose does not give better relief and can cause side effects such as diarrhoea, constipation or electrolyte problems. - Myth: This medicine is completely free of interactions.
Fact: Antacids can reduce the absorption of many medicines, so a gap of at least two hours is usually needed between this medicine and other oral drugs. - Myth: It is safe to take this medicine for months without review.
Fact: Prolonged use can cause mineral accumulation and electrolyte disturbances, especially in kidney disease. Long-term use should be reviewed by a doctor.
🔄 Alternative Options
Generic Alternatives
- Magaldrate and simethicone oral gel
- Magaldrate oral suspension
- Simethicone oral emulsion