nca tablet - Magaldrate (800mg) + Simethicone (50mg) medicine

Megaswiss 800 mg/50 mg Tablet: Complete Medicine Guide

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🏭 Troikaa Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of acid-related disorders and bloating.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or black, tarry stools
  • Severe abdominal pain or distension
  • Difficulty breathing or swelling of face, lips, or throat
  • Chest pain or irregular heartbeat
  • Confusion, muscle weakness, or seizures
  • Decreased urine output or swelling in legs
  • Persistent vomiting or inability to keep fluids down

If experiencing severe symptoms, call emergency services immediately.

What is nca tablet used for?

This medicine is a combination of Magaldrate and Simethicone used to relieve heartburn, acid indigestion, and bloating. It works by neutralising stomach acid and reducing gas bubbles.

  • Generic Name: Magaldrate (800mg) + Simethicone (50mg)
  • Manufacturer: Troikaa Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nca tablet के बारे में (Hindi Summary)

उपयोग: यह दवा मैगल्ड्रेट और सिमेथिकोन का संयोजन है, जिसका उपयोग सीने में जलन, एसिडिटी, गैस और पेट फूलने से राहत पाने के लिए किया जाता है। यह पेट में अतिरिक्त एसिड को बेअसर करती है और गैस के बुलबुले को तोड़कर बाहर निकालने में मदद करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त या कब्ज, मतली, पेट में असुविधा शामिल हैं। दुर्लभ मामलों में एलर्जी, गंभीर कब्ज या इलेक्ट्रोलाइट असंतुलन हो सकता है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खाने के बाद लें। अन्य दवाओं के साथ लेने से पहले कम से कम 2 घंटे का अंतराल रखें। शराब और कैफीन से बचें। दो सप्ताह से अधिक उपयोग न करें। गुर्दे की बीमारी में सावधानी बरतें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 nca tablet Uses & Benefits

[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Provides symptomatic relief from heartburn and acid regurgitation by neutralising gastric acid.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Helps alleviate postprandial fullness, epigastric pain, and burning sensation associated with dyspepsia.","evidence":"Moderate"},{"condition":"Bloating and flatulence","description":"Simethicone reduces gas bubbles, providing relief from abdominal distension and discomfort.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Used as an adjunct to acid-suppressing therapy for symptomatic relief of ulcer pain.","evidence":"Adjunctive"},{"condition":"Gastritis","description":"Neutralises excess acid and provides symptomatic relief in acute or chronic gastritis.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Prevention of stress ulcers","description":"Sometimes used in critically ill patients as part of stress ulcer prophylaxis, though proton pump inhibitors are preferred.","evidence":"Limited"},{"condition":"Medication-induced dyspepsia","description":"May be used to relieve dyspepsia caused by nonsteroidal anti-inflammatory drugs or other medications.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease (GERD)

Also treats: Functional dyspepsia, Gastritis, Peptic ulcer disease, Bloating and flatulence

📋 Drug Information

Generic Name(s)Magaldrate (800mg) + Simethicone (50mg)
Brand Namenca tablet
ManufacturerTroikaa Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine after meals to prolong its effect and reduce stomach upset.
2
Maintain a gap of at least 2 hours between this medicine and other medications to avoid absorption issues.
3
Do not use this medicine for more than 2 weeks without consulting a doctor.
4
If you have kidney disease, use this medicine only under medical supervision.
5
Avoid alcohol and caffeine as they can worsen acid symptoms.
6
Report any severe abdominal pain, constipation, or allergic reactions immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Heartburn
This medicine is commonly used for heartburn relief.
Likely Use
✅
Bloating
Simethicone helps relieve bloating.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not indicated for headaches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMagaldrate is minimally absorbed systemically; its action is primarily local in the gastrointestinal tract. Simethicone is not absorbed from the gastrointestinal tract and is excreted unchanged in faeces.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismMagaldrate is not metabolised; it is excreted in faeces as insoluble salts. Simethicone is chemically inert and not metabolised.
Half-LifeNot established from the available information.
ExcretionMagaldrate and simethicone are excreted primarily in faeces. Small amounts of absorbed aluminium and magnesium may be excreted renally.
BioavailabilityNot established from the available information.
Onset of ActionAcid neutralisation begins within minutes of ingestion. Simethicone's defoaming effect also starts rapidly.
Peak Plasma TimeNot applicable due to minimal systemic absorption.
Duration of ActionThe effect lasts approximately 30 to 60 minutes when taken on an empty stomach, but may last up to 3 hours if taken after a meal.

How It Works

This medicine combines two active ingredients with complementary actions. Magaldrate is a balanced mixture of aluminium and magnesium hydroxides that neutralises gastric acid, raising gastric pH and reducing pepsin activity. Simethicone is a non-absorbed surfactant that lowers surface tension of gas bubbles in the gastrointestinal tract, causing them to merge into larger bubbles that are more easily passed. Together, they provide rapid relief from acid-related symptoms and bloating.

Mechanism Steps

1
Acid neutralisation: Magaldrate reacts with hydrochloric acid in the stomach to form water and neutral salts, thereby reducing gastric acidity.
2
Pepsin inhibition: By raising gastric pH, magaldrate reduces the activity of pepsin, an enzyme that can damage the stomach lining.
3
Gas bubble coalescence: Simethicone lowers surface tension of gas bubbles, causing them to merge into larger bubbles.
4
Gas expulsion: The larger gas bubbles are more easily propelled through the gastrointestinal tract and expelled, relieving bloating.

💡 How to Take nca tablet

Strength: Each tablet contains Magaldrate 800 mg and Simethicone 50 mg.

1Swallow the tablet whole with a glass of water.
2Take after meals or as directed by your doctor.
3Do not crush or chew the tablet unless advised.
4Maintain a gap of at least 2 hours between this medicine and other medications.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 1 to 2 tablets taken 3 to 4 times daily, preferably after meals and at bedtime, or as directed by your doctor. Do not exceed 8 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of antacids, especially those with renal impairment. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentUse with caution in patients with renal impairment. Dose reduction or avoidance may be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentNo specific dosage adjustment is required for hepatic impairment, but consult a doctor for guidance.
Maximum Daily DoseDo not exceed 8 tablets in 24 hours.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take after meals
Food buffers the effect and prolongs action.
Citrus fruits
Avoid taking together
May increase stomach acid.
Alcohol
Avoid
Increases acid secretion and worsens symptoms.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nca tablet

✅ Common Side Effects

Diarrhoea (Common (5-10%))
Usually resolves on its own. If persistent, consult your doctor.
Constipation (Common (5-10%))
Increase fluid and fibre intake. Consult doctor if severe.
Nausea (Uncommon (1-5%))
Take with food to reduce nausea. Consult doctor if it persists.
Abdominal discomfort (Uncommon (1-5%))
Usually transient. If it continues, speak to your doctor.

🚨 Serious Side Effects

Severe constipation or intestinal obstruction (Rare (<0.1%))
Seek immediate medical attention if you have severe abdominal pain, vomiting, or inability to pass stool.
Aluminium toxicity (Rare (<0.1%))
Symptoms include confusion, muscle weakness, and seizures. Seek emergency care if these occur, especially in kidney disease patients.
Hypermagnesaemia (Rare (<0.1%))
Symptoms include low blood pressure, nausea, and flushing. Seek medical attention if you have kidney problems and experience these.
Allergic reactions (Rare (<0.1%))
Stop the medicine and seek immediate medical help if you develop rash, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Hypophosphataemia
Prolonged use may lead to low phosphate levels. Consult doctor if you experience bone pain or muscle weakness.
Osteomalacia
Long-term high-dose aluminium antacids can cause bone softening. Avoid prolonged use without medical supervision.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tetracycline Major
Fluoroquinolones Major
Iron supplements Major
Levothyroxine Major
Digoxin Moderate
Ketoconazole Moderate
Atazanavir Moderate
Aspirin Minor
Cimetidine Minor

🚨 Major Interactions

  • Tetracycline antibiotics
  • Fluoroquinolone antibiotics
  • Iron supplements
  • Levothyroxine

⚡ Moderate Interactions

  • Digoxin
  • Ketoconazole
  • Atazanavir

🍷 Alcohol Interaction

Alcohol can increase gastric acid production and irritate the stomach lining, potentially worsening the condition being treated. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to magaldrate, simethicone, or any component of the formulation","Severe renal impairment or dialysis","Hypermagnesaemia","Suspected or confirmed bowel obstruction","Hypophosphataemia"]

⚠️ Warnings & Precautions

["Do not use for more than 2 weeks without medical advice.","Use with caution in patients with renal impairment, heart failure, or on magnesium-restricted diets.","Antacids may mask symptoms of more serious conditions such as gastric cancer.","Avoid concomitant use with other medications without consulting a doctor, as absorption may be affected.","Not recommended for children under 12 years without medical advice."]

🤱 Lactation Safety

Magaldrate and simethicone are not known to be excreted in breast milk in significant amounts. However, consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose may cause diarrhoea, constipation, or electrolyte imbalances. Treatment is symptomatic and supportive. In case of overdose, seek medical attention immediately. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as directed by your doctor or as per the label. Do not exceed the recommended dose. Shake the suspension well if using a liquid form; for tablets, swallow whole with a glass of water. Take this medicine with or after meals for best effect. Maintain a gap of at least two hours between this medicine and other medications, as it can reduce their absorption. Avoid alcohol and caffeine, which can worsen acid symptoms. If symptoms persist beyond two weeks, consult a doctor. Do not use this medicine for prolonged periods without medical advice, especially if you have kidney disease, heart failure, or are on a magnesium-restricted diet. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients, especially those with renal impairment, are at higher risk of electrolyte imbalances. Use with caution and monitor renal function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. It is generally considered safe for occasional use, but medical advice is recommended.

🏥 Post-Surgery Considerations

After surgery, use this medicine only if prescribed by your surgeon. It may interact with other postoperative medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It is generally safe for dental procedures, but maintain a gap with other medications.

💚 Lifestyle Tips for Better Results

🏃
Eat smaller, more frequent meals to reduce acid production.
🥗
Avoid spicy, fatty, and acidic foods that trigger heartburn.
😴
Maintain a healthy weight to reduce pressure on the stomach.
💧
Elevate the head of your bed to prevent night-time reflux.
🧘
Avoid lying down immediately after eating.
🌞
Quit smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Avoid vigorous exercise immediately after meals, as it can worsen reflux. Light walking after meals may aid digestion.

🥗 Diet Recommendations

Include fibre-rich foods like fruits and vegetables.
Choose lean proteins and whole grains.
Avoid caffeine, chocolate, and mint, which can relax the lower oesophageal sphincter.
Stay hydrated with water throughout the day.

💼 Impact on Daily Work & Life

This medicine is generally safe and does not affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness, avoid these activities until you feel normal.

🛑 When to Stop This Medicine

Stop taking this medicine and consult a doctor if symptoms persist beyond 2 weeks, worsen, or if you experience any severe side effects. Do not stop prescribed medications without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine without medical supervision can lead to electrolyte imbalances, particularly in patients with kidney disease. It may also cause acid rebound. Regular monitoring of electrolytes and renal function is advised for prolonged use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary modifications

Avoiding trigger foods can reduce acid symptoms.

Evidence: Well-established
Lifestyle changes

Weight loss, smoking cessation, and elevating the head of the bed can help.

Evidence: Well-established
Herbal remedies

Some herbs like ginger and chamomile may soothe the stomach, but evidence is limited.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If travelling across time zones, continue your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old software engineer with frequent acidity and bloating after meals.
He started taking this medicine after meals as prescribed. Within a few days, his heartburn and bloating reduced significantly. He also cut down on spicy food and caffeine, which helped further.
💡 Lesson: Taking the medicine after meals and making dietary changes can provide better relief.
👤 A 60-year-old woman with mild kidney disease and occasional heartburn.
She was advised to use this medicine sparingly due to her kidney condition. She consulted her doctor before each use and monitored her symptoms. She experienced relief without any complications.
💡 Lesson: Patients with kidney disease should use antacids only under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within minutes of ingestion, providing rapid relief from heartburn and bloating.

Q: Can I take it with other medicines?

A: It can interact with many medicines, reducing their absorption. Maintain a gap of at least 2 hours between this medicine and other medications.

Q: Is it safe during pregnancy?

A: It is generally considered safe for occasional use during pregnancy, but consult your doctor before taking it.

Q: What are the common side effects?

A: Common side effects include diarrhoea, constipation, nausea, and abdominal discomfort. These are usually mild and transient.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for nca tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure ulcers.
    Fact: This medicine provides symptomatic relief but does not cure ulcers. Ulcers require specific treatment.
  • Myth: It is safe to take this medicine indefinitely.
    Fact: Prolonged use without medical supervision can lead to electrolyte imbalances and other complications.
  • Myth: This medicine can be taken with all other medications.
    Fact: It can interact with many drugs, reducing their absorption. Always consult a doctor or pharmacist.

🔄 Alternative Options

Generic Alternatives

  • Magaldrate + Simethicone combination tablets
  • Magaldrate + Simethicone suspension

Brand Alternatives

  • Megaswiss 800 mg/50 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Magaldrate + Simethicone","composition":"Magaldrate 800 mg + Simethicone 50 mg","onset":"Rapid","duration":"Up to 3 hours","notes":"Balanced antacid with antiflatulent"},{"medicine":"Aluminium hydroxide + Magnesium hydroxide + Simethicone","composition":"Aluminium hydroxide 200 mg + Magnesium hydroxide 200 mg + Simethicone 25 mg","onset":"Rapid","duration":"Up to 3 hours","notes":"Similar action, different salt combination"},{"medicine":"Calcium carbonate + Simethicone","composition":"Calcium carbonate 500 mg + Simethicone 40 mg","onset":"Rapid","duration":"Up to 2 hours","notes":"May cause acid rebound"}]

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