Glinate 60 Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe hypoglycemia with confusion, seizures, or loss of consciousness
- Signs of a severe allergic reaction such as swelling of the face, lips, or throat, or difficulty breathing
- Persistent vomiting or diarrhea leading to dehydration
- Unusual bleeding or bruising
- Yellowing of the skin or eyes
- Severe abdominal pain
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is trunate 60 tablet used for?
This medicine is an oral antidiabetic drug used to lower post-meal blood sugar in adults with type 2 diabetes. It is taken before meals and works by stimulating insulin release from the pancreas.
- Generic Name: Nateglinide (60mg)
- Manufacturer: AAR ESS Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 trunate 60 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज वाले वयस्कों में खाने के बाद बढ़ने वाले ब्लड शुगर को कंट्रोल करने के लिए इस्तेमाल की जाती है। यह अग्न्याशय से इंसुलिन निकलने में मदद करती है, खासकर खाने के बाद जब शुगर बढ़ती है। इसे आमतौर पर खाने से पहले लिया जाता है। यह दवा डायबिटीज को पूरी तरह ठीक नहीं करती, बल्कि डाइट और एक्सरसाइज के साथ मिलकर शुगर को नियंत्रित रखने में मदद करती है।
साइड इफेक्ट्स: इस दवा के आम साइड इफेक्ट्स में लो ब्लड शुगर (हाइपोग्लाइसीमिया), चक्कर आना, कमजोरी, पसीना आना, भूख लगना, जोड़ों में दर्द, दस्त और सर्दी-जुकाम जैसे लक्षण शामिल हो सकते हैं। अगर शुगर बहुत कम हो जाए तो बेहोशी या दौरे भी पड़ सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार खाने से पहले लें। खाना न छोड़ें, वरना शुगर कम हो सकती है। हमेशा अपने पास ग्लूकोज या मिठाई रखें। शराब न पिएं क्योंकि इससे शुगर कम होने का खतरा बढ़ जाता है। ब्लड शुगर की नियमित जांच करें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं।
💊 trunate 60 tablet Uses & Benefits
[{"condition":"Type 2 diabetes mellitus (post-meal glucose control)","description":"This medicine is used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes by reducing postprandial blood glucose excursions.","evidence":"Well-established"},{"condition":"Type 2 diabetes mellitus (combination therapy)","description":"It may be used in combination with metformin or other oral antidiabetic agents when monotherapy does not achieve target blood glucose levels.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Impaired glucose tolerance","description":"Sometimes studied or used off-label to delay progression to type 2 diabetes in people with impaired glucose tolerance, but this is not a standard approved indication.","evidence":"Limited"}]
Primary treatment for: Type 2 diabetes mellitus
Also treats: Impaired glucose tolerance, Metabolic syndrome
📋 Drug Information
| Generic Name(s) | Nateglinide (60mg) |
| Brand Name | trunate 60 tablet |
| Manufacturer | AAR ESS Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Meglitinides (Insulin Secretogogues) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | Refer to the packaging for the expiry date. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a meglitinide analog that stimulates insulin secretion from pancreatic beta cells by closing ATP-sensitive potassium channels. This closure causes membrane depolarization, calcium influx, and release of insulin. The effect is glucose-dependent, so insulin secretion is enhanced mainly when blood glucose is elevated, such as after a meal.
Mechanism Steps
💡 How to Take trunate 60 tablet
Strength: Immediate-release tablet, 60 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 60 mg or 120 mg taken orally within 30 minutes before each meal, up to three times daily. The dose depends on your blood glucose levels, kidney and liver function, and other medicines you take. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the glucose-lowering effects and are at higher risk of hypoglycemia. Start with a lower dose and monitor blood glucose closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be needed based on kidney function. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be needed. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 360 mg (120 mg three times daily before meals). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of trunate 60 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | |
| Sulfonylureas | Major | |
| Metformin | Major | |
| Beta-blockers | Major | |
| MAOIs | Major | |
| Fluconazole | Moderate | |
| Ketoconazole | Moderate | |
| NSAIDs | Moderate | |
| Thiazide diuretics | Minor | |
| Corticosteroids | Minor |
🚨 Major Interactions
- Other antidiabetic agents (e.g., insulin, sulfonylureas, metformin)
- Beta-blockers
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- CYP2C9 inhibitors (e.g., fluconazole)
- CYP3A4 inhibitors (e.g., ketoconazole)
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
🍷 Alcohol Interaction
Alcohol can increase the risk of hypoglycemia and may make its symptoms harder to recognize. It is best to avoid alcohol while taking this medicine, or to limit intake and monitor blood glucose closely if you do drink.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to nateglinide or any component of the formulation","Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe hepatic impairment"]
⚠️ Warnings & Precautions
["May cause hypoglycemia; monitor blood glucose regularly.","Take before meals; skipping meals increases hypoglycemia risk.","Use with caution in elderly patients and those with renal or hepatic impairment.","Avoid alcohol as it can increase hypoglycemia risk.","Not for use in type 1 diabetes or diabetic ketoacidosis.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor.
💊 Overdose Management
Overdose can cause severe hypoglycemia. If overdose is suspected, seek emergency medical attention immediately. Treatment may include intravenous glucose and close monitoring of blood glucose and vital signs.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if there is still time before your next meal. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor, usually within 30 minutes before a meal. Do not skip meals after taking this medicine, because doing so increases the risk of low blood sugar. Carry a fast-acting source of sugar such as glucose tablets or candy with you at all times in case of hypoglycemia. Check your blood glucose regularly, especially during illness, stress, or changes in diet or activity. Avoid drinking alcohol because it can make low blood sugar more likely and harder to recognize. Tell your doctor about all other medicines, supplements, and herbal products you take, because some can interact with this medicine. Do not drive or operate heavy machinery if you feel dizzy or have symptoms of low blood sugar. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Keep this medicine out of reach of children and store it as directed on the label.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of hypoglycemia and may need lower doses. Regular monitoring of blood glucose, kidney function, and overall health is important.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before conception. This medicine is not recommended during pregnancy unless clearly needed. Your doctor may switch you to a safer alternative.
🏥 Post-Surgery Considerations
After surgery, blood sugar control is important. Inform your surgical team about this medicine. Your doctor will decide whether to continue, adjust, or temporarily stop it.
🦷 Dental Procedures
Inform your dentist about this medicine. If you are having a procedure that requires fasting, discuss dose adjustments with your doctor to avoid hypoglycemia.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise can lower blood sugar. Check your blood glucose before and after exercise, and carry a fast-acting sugar source. Adjust your medicine dose only under medical advice.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or low blood sugar, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Inform your employer if your job involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or your blood sugar is well controlled on other treatments, your doctor may adjust or stop it.
📅 Long-Term Use Effects
Long-term use of this medicine may help maintain blood sugar control, but it requires regular monitoring of blood glucose, HbA1c, and kidney and liver function. Prolonged uncontrolled diabetes can lead to complications, so lifestyle measures and regular follow-up are essential.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A personalized diet plan can help control blood sugar and complement medicine.
Evidence: Well-establishedExercise improves insulin sensitivity and helps lower blood sugar.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
People with diabetes should stay up to date with recommended vaccines, including influenza and COVID-19 vaccines. Discuss timing with your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. If crossing time zones, adjust meal times and doses in consultation with your doctor. Store away from direct sunlight and moisture. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within 15 to 30 minutes after taking it, with peak effect in about 1 hour.
A: It should be used with caution in kidney impairment. Your doctor may adjust the dose and monitor you closely.
A: These are signs of low blood sugar. Eat or drink something sugary immediately, such as glucose tablets or fruit juice, and inform your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for trunate 60 tablet
View AllAlternative brands with exact same active ingredient:
-
Natelide 60mg TabletAlembic Pharmaceuticals Ltd ₹28.84 86.9% CHEAPER
-
natiz 60mg tabletIntas Pharmaceuticals Ltd ₹53.75 75.6% CHEAPER
-
glinate 60 tabletGlenmark Pharmaceuticals Ltd ₹88.13 60% CHEAPER
-
natnox 60mg tabletNectazen Pharmaceuticals ₹225.00 2.1% COSTLIER
-
nateglide 60mg tabletDruto Laboratories ₹229.00 3.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps control blood sugar but does not cure diabetes. It must be used along with diet, exercise, and regular monitoring. - Myth: This medicine can be taken without meals.
Fact: This medicine should be taken before meals to work properly and reduce the risk of low blood sugar. - Myth: This medicine is safe for everyone with diabetes.
Fact: It is not for people with type 1 diabetes or diabetic ketoacidosis, and it requires medical supervision.
🔄 Alternative Options
Generic Alternatives
- Nateglinide 60 mg tablet
Brand Alternatives
- Glinate 60 Tablet