Trox 50mg Injection - Tramadol (50mg/ml) medicine

Admadol 100mg Injection: Complete Medicine Guide

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🏭 Lifekyor Pharmaceuticals 📦 vial of 2 ml Injection 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for acute pain; established for chronic pain.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Slow, shallow, or irregular breathing
  • Severe dizziness or fainting
  • Seizures or convulsions
  • Chest pain or palpitations
  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Confusion or hallucinations
  • Extreme drowsiness or inability to wake up

If experiencing severe symptoms, call emergency services immediately.

What is Trox 50mg Injection used for?

This medicine is a tramadol injection used for moderate to severe pain. It works by blocking pain signals in the brain and spinal cord. It is given by a healthcare professional and is not for self-administration.

  • Generic Name: Tramadol (50mg/ml)
  • Manufacturer: Lifekyor Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Trox 50mg Injection के बारे में (Hindi Summary)

उपयोग: यह दवा ट्रामाडोल इंजेक्शन है, जिसका उपयोग मध्यम से गंभीर दर्द के इलाज के लिए किया जाता है। यह दर्द को कम करने के लिए मस्तिष्क और रीढ़ की हड्डी में दर्द के संकेतों को रोकती है। यह आमतौर पर सर्जरी के बाद, चोट लगने पर, या अन्य गंभीर दर्द की स्थितियों में दी जाती है। यह दवा केवल डॉक्टर या स्वास्थ्य कर्मचारी द्वारा ही दी जानी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, चक्कर आना, नींद आना, पसीना आना और मुँह सूखना शामिल हैं। गंभीर दुष्प्रभावों में सांस लेने में कठिनाई, दौरे पड़ना, और एलर्जी की प्रतिक्रिया शामिल हो सकती है। यदि आपको कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य कर्मचारी द्वारा ही दी जानी चाहिए। इसे स्वयं न लें। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। इस दवा को लेते समय शराब न पिएं। जब तक आपको पता न चले कि यह दवा आप पर कैसे असर करती है, वाहन न चलाएं। यदि सांस लेने में कठिनाई, सीने में दर्द, या गंभीर चक्कर आए तो तुरंत आपातकालीन चिकित्सा सहायता लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 Trox 50mg Injection Uses & Benefits

[{"condition":"Moderate to severe acute pain","description":"This medicine is used for the short-term management of moderate to severe pain, such as post-operative pain or pain from injuries.","evidence":"Well-established"},{"condition":"Chronic pain","description":"It may be used for chronic pain conditions when non-opioid analgesics are insufficient, but only under close medical supervision.","evidence":"Established"},{"condition":"Pain associated with surgical procedures","description":"Administered before or after surgery to manage procedural pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Neuropathic pain","description":"Sometimes prescribed off-label for certain types of nerve pain, though evidence is limited.","evidence":"Limited"},{"condition":"Premature ejaculation","description":"Off-label use for delaying ejaculation, but not recommended due to side effects.","evidence":"Limited"}]

Primary treatment for: Moderate to severe pain

Also treats: Post-operative pain, Chronic pain, Injury-related pain

📋 Drug Information

Generic Name(s)Tramadol (50mg/ml)
Brand NameTrox 50mg Injection
ManufacturerLifekyor Pharmaceuticals
Packaging / Formvial of 2 ml Injection (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationParenteral (intramuscular or intravenous injection)
StorageStore below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always administer this medicine slowly intravenously to avoid respiratory depression.
2
Monitor patients for signs of serotonin syndrome when combining with antidepressants.
3
Use the lowest effective dose for the shortest duration possible.
4
Assess renal and hepatic function before and during therapy.
5
Warn patients about the risk of dependence and withdrawal.
6
Avoid concurrent use with MAOIs and other opioids.
7
In elderly patients, start with a lower dose and titrate carefully.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Moderate to severe pain
This medicine is commonly prescribed for this.
Likely Use
❌
Mild headache
This medicine is not a primary treatment for mild headache.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing intramuscular administration, this medicine is rapidly and completely absorbed. The bioavailability is approximately 100% for intramuscular and intravenous routes.
DistributionThis medicine distributes widely throughout the body. It crosses the blood-brain barrier and the placenta. The volume of distribution is approximately 2.5 to 3 L/kg.
Protein BindingApproximately 20% of this medicine binds to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP2D6 and CYP3A4. The active metabolite O-desmethyltramadol is responsible for much of the analgesic effect.
Half-LifeThe elimination half-life of this medicine is approximately 5 to 6 hours. The active metabolite has a longer half-life of about 7 to 9 hours.
ExcretionThis medicine and its metabolites are primarily excreted by the kidneys. About 90% of the dose is eliminated via urine.
BioavailabilityThe bioavailability of this medicine after intramuscular injection is approximately 100%.
Onset of ActionPain relief typically begins within 10 to 15 minutes after intramuscular injection.
Peak Plasma TimePeak plasma concentration is reached approximately 45 minutes after intramuscular administration.
Duration of ActionThe analgesic effect of this medicine lasts for about 4 to 6 hours.

How It Works

This medicine works by two complementary mechanisms. It binds to mu-opioid receptors in the central nervous system, which reduces pain perception. Additionally, it inhibits the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. This dual action makes it effective for moderate to severe pain.

Mechanism Steps

1
Mu-opioid receptor binding: This medicine binds to mu-opioid receptors in the brain and spinal cord, inhibiting pain signal transmission.
2
Monoamine reuptake inhibition: It blocks the reuptake of serotonin and norepinephrine, which enhances descending pain inhibition.
3
Pain perception reduction: The combined actions reduce the perception of pain and increase pain tolerance.

💡 How to Take Trox 50mg Injection

Strength: Injection: 50 mg/mL

1This medicine is given by a healthcare professional.
2It is administered as an intramuscular or intravenous injection.
3For intravenous use, it is given slowly over 2 to 3 minutes.
4Do not self-administer.
5Follow your healthcare provider's instructions exactly.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 50 to 100 mg administered intramuscularly or intravenously every 4 to 6 hours as needed for pain. The maximum daily dose is 400 mg. For intravenous administration, it should be given slowly over 2 to 3 minutes. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageIn elderly patients over 65 years, the dose should be reduced and the dosing interval extended. The maximum daily dose should not exceed 300 mg. Use with caution due to increased risk of respiratory depression and falls.
Renal ImpairmentIn patients with renal impairment, the dosing interval should be extended. For creatinine clearance less than 30 mL/min, the maximum daily dose should not exceed 200 mg. Use with caution.
Hepatic ImpairmentIn patients with hepatic impairment, the dose should be reduced and the dosing interval extended. For severe hepatic impairment, this medicine is contraindicated.
Maximum Daily Dose400 mg per day for adults. In elderly and renal impairment, lower maximum doses apply.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific timing required
This medicine is given by injection, so food does not affect its absorption.
Alcohol
Avoid
Increases sedation and respiratory depression risk.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Trox 50mg Injection

✅ Common Side Effects

Nausea (Common (5-10%))
Usually resolves on its own. If persistent, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Rest if needed. Do not drive.
Sweating (Common (5-10%))
Stay hydrated.
Dry mouth (Common (5-10%))
Sip water or chew sugar-free gum.

🚨 Serious Side Effects

Respiratory depression (Rare (<0.1%))
Seek immediate medical attention if breathing becomes slow or shallow.
Seizures (Rare (<0.1%))
Call emergency services if a seizure occurs.
Serotonin syndrome (Rare (<0.1%))
Seek immediate care if you experience agitation, hallucinations, fast heartbeat, fever, or muscle twitching.
Severe allergic reaction (Rare (<0.1%))
Get emergency help if you have rash, itching, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Hallucinations
Report to your doctor immediately.
Dependence and withdrawal
Do not stop abruptly; consult your doctor for a tapering plan.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
SSRIs Major
Other opioids Major
CYP2D6 inhibitors Moderate
CYP3A4 inducers Moderate
Warfarin Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • SSRIs, SNRIs, tricyclic antidepressants
  • Other opioids

⚡ Moderate Interactions

  • CYP2D6 inhibitors (e.g., fluoxetine, quinidine)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)

🍷 Alcohol Interaction

Alcohol should be avoided while receiving this medicine because it can increase sedation, respiratory depression, and the risk of seizures.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to tramadol","Severe respiratory depression","Acute or severe asthma","Concurrent use of MAOIs","Children under 12 years of age","Uncontrolled epilepsy","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["Risk of respiratory depression, especially in elderly or debilitated patients.","May cause seizures, particularly in patients with a history of seizures or those taking other seizure-threshold-lowering drugs.","Risk of serotonin syndrome when used with serotonergic drugs.","May cause dependence and withdrawal syndrome.","Avoid use in patients with head injury or increased intracranial pressure.","Use with caution in patients with renal or hepatic impairment.","May impair mental and physical abilities required for driving or operating machinery."]

🤱 Lactation Safety

This medicine passes into breast milk and may cause sedation and respiratory depression in a nursing infant. It is not recommended during breastfeeding. Consult your doctor for alternatives.

💊 Overdose Management

Overdose of this medicine can cause respiratory depression, seizures, and coma. Treatment includes supportive care, maintenance of airway and ventilation, and administration of naloxone if opioid effects are prominent. Seizures may require benzodiazepines. Hemodialysis may be considered in severe cases. Seek emergency medical help immediately.

⏰ Missed Dose

This medicine is usually given by a healthcare professional in a controlled setting. If you miss a scheduled dose, contact your healthcare provider for instructions. Do not attempt to self-administer a double dose.

Additional Safety Advice

General Safety

This medicine must be administered only by a qualified healthcare professional. Do not attempt to self-administer. Inform your doctor about all other medicines you are taking, especially antidepressants, antipsychotics, and other opioids. Avoid alcohol and other central nervous system depressants while receiving this medicine. Do not drive or operate heavy machinery until you know how this medicine affects you. If you experience difficulty breathing, chest pain, or severe dizziness, seek emergency medical help immediately. Do not stop this medicine abruptly without medical advice, as withdrawal symptoms may occur.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of respiratory depression, falls, and confusion. Lower doses and extended dosing intervals are recommended. Close monitoring is essential.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy unless clearly needed. If you are planning pregnancy, consult your doctor to discuss safer alternatives.

🏥 Post-Surgery Considerations

This medicine is often used for post-operative pain. It should be administered by a healthcare professional. Monitor for respiratory depression and other side effects.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine, as it may interact with anesthetics and other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Follow your doctor's instructions for pain management.
🥗
Avoid alcohol and other central nervous system depressants.
😴
Do not drive or operate heavy machinery until you know how this medicine affects you.
💧
Stay hydrated and maintain a healthy diet.
🧘
Get adequate rest to aid recovery.
🌞
Report any unusual symptoms to your doctor promptly.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. Dizziness and drowsiness may increase the risk of falls.

🥗 Diet Recommendations

Eat a balanced diet to support recovery.
Avoid alcohol.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may impair your ability to drive or operate machinery. Avoid these activities until you know how it affects you. Inform your employer if your job requires alertness.

🛑 When to Stop This Medicine

Do not stop this medicine abruptly without consulting your doctor, as withdrawal symptoms may occur. Your doctor will gradually reduce the dose if needed.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to tolerance, dependence, and withdrawal syndrome. It may also increase the risk of seizures and serotonin syndrome. Regular monitoring of pain control, renal and hepatic function, and signs of dependence is recommended. Use for the shortest duration possible.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Non-opioid analgesics

Medicines like paracetamol or NSAIDs may be used for mild to moderate pain.

Evidence: Well-established
Physical therapy

Can complement medicine for chronic pain management.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store below 30°C

❌ DON'T

Do not freeze

✅ DO

Protect from light

❌ DON'T

Do not use if solution is discolored or contains particles

✅ DO

Keep out of reach of children

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from light. If traveling across time zones, consult your doctor for dosing schedule adjustments. Check local customs regulations regarding controlled substances. Never leave it in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with severe knee pain after surgery
He received this medicine as an injection every 6 hours. His pain improved significantly within 15 minutes of each dose. He experienced mild nausea, which was managed with an antiemetic. He was advised not to drive and to avoid alcohol.
💡 Lesson: This medicine provides rapid pain relief but requires monitoring for side effects and strict adherence to safety advice.
👤 A 70-year-old woman with chronic back pain
She was given this medicine for acute exacerbation of chronic back pain. The dose was reduced due to her age and mild renal impairment. She reported good pain relief but felt drowsy. She was advised to avoid falls and to have someone assist her.
💡 Lesson: Elderly patients require lower doses and close monitoring for sedation and respiratory depression.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts relieving pain within 10 to 15 minutes after injection.

Q: How long does the effect last?

A: The pain relief typically lasts for 4 to 6 hours.

Q: Can I take this medicine at home?

A: No, this medicine must be administered by a healthcare professional.

Q: What are the serious side effects?

A: Serious side effects include respiratory depression, seizures, serotonin syndrome, and severe allergic reactions. Seek immediate medical help if these occur.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Trox 50mg Injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Tramadol is a safe painkiller with no addiction risk.
    Fact: Tramadol can cause dependence and withdrawal, and it carries a risk of abuse.
  • Myth: Tramadol injection can be self-administered.
    Fact: This medicine must be given by a healthcare professional only.

🔄 Alternative Options

Generic Alternatives

  • Tramadol injection

Brand Alternatives

  • Admadol 100mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Tramadol","class":"Opioid analgesic","route":"Parenteral","common_use":"Moderate to severe pain"},{"medicine":"Morphine","class":"Opioid analgesic","route":"Parenteral","common_use":"Severe pain"}]

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