acekyor-d 80mg/100mg tablet - Drotaverine (80mg) + Aceclofenac (100mg) medicine

Acekyor-D 80mg/100mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Lifekyor Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is acekyor-d 80mg/100mg tablet used for?

Acekyor-D 80mg/100mg Tablet is a combination medicine used to treat pain and muscle spasms associated with gastrointestinal disorders. It contains Drotaverine, which relaxes smooth muscles, and Aceclofenac, a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. It is typically taken twice daily with food.

  • Generic Name: Drotaverine + Aceclofenac
  • Manufacturer: Lifekyor Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š acekyor-d 80mg/100mg tablet Uses & Benefits

Treatment of smooth muscle spasms associated with pain, such as in gastrointestinal, biliary, and renal colic

Off-label uses: Dysmenorrhea, musculoskeletal pain

๐Ÿ“‹ Drug Information

Generic Name(s)Drotaverine + Aceclofenac
Brand NameAceclo Spas Tablet
ManufacturerLifekyor Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntispasmodic + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributed widely in body tissues
Protein BindingDrotaverine: 95-98%; Aceclofenac: >99%
MetabolismDrotaverine: Hepatic; Aceclofenac: Hepatic via CYP2C9
Half-LifeDrotaverine: 7-12 hours; Aceclofenac: 4 hours
ExcretionDrotaverine: Renal and fecal; Aceclofenac: Renal (primarily as metabolites)
BioavailabilityDrotaverine: ~50%; Aceclofenac: ~100%
Onset of ActionDrotaverine: 30-60 minutes; Aceclofenac: 30 minutes
Peak Plasma TimeDrotaverine: 1-2 hours; Aceclofenac: 1.25-3 hours
Duration of ActionDrotaverine: 4-6 hours; Aceclofenac: 12 hours

How It Works

Drotaverine inhibits phosphodiesterase-4, increasing cAMP, leading to smooth muscle relaxation. Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis.

Mechanism Steps

1Drotaverine inhibits PDE4, increasing cAMP in smooth muscle cells
2Increased cAMP leads to relaxation of smooth muscle in GI tract, biliary tract, and uterus
3Aceclofenac inhibits COX-1 and COX-2 enzymes

๐Ÿ’ก How to Take acekyor-d 80mg/100mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of acekyor-d 80mg/100mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Abdominal pain

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Agranulocytosis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal bleeding
Lithium Moderate Increased lithium levels and toxicity
Methotrexate Major Increased methotrexate toxicity

๐Ÿšจ Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin
  • Other NSAIDs

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine

๐Ÿฝ๏ธ Food Interactions

May be taken with food to reduce GI upset

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, active peptic ulcer, severe renal/hepatic impairment, third trimester pregnancy, history of asthma with NSAIDs

๐Ÿ“Š Monitoring Parameters

Liver function, renal function, blood pressure, signs of GI bleeding

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage if recent ingestion

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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