travoprostin-t ophthalmic solution - Timolol (5mg) + Travoprost (40mcg) medicine

Travacom Eye Drop: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Eyekare Kilitch Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for the treatment of open-angle glaucoma and ocular hypertension.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden decrease in vision or eye pain
  • Severe eye redness, swelling, or discharge
  • Chest pain, shortness of breath, or wheezing
  • Slow or irregular heartbeat, dizziness, or fainting
  • Swelling of face, lips, tongue, or throat
  • Severe headache with visual changes

If experiencing severe symptoms, call emergency services immediately.

What is travoprostin-t ophthalmic solution used for?

This medicine is a combination eye drop containing timolol and travoprost. It is used to lower high pressure inside the eye in conditions like open-angle glaucoma and ocular hypertension. It works by reducing fluid production and increasing fluid drainage from the eye. It is usually applied once daily in the affected eye(s).

  • Generic Name: Timolol (5mg) + Travoprost (40mcg)
  • Manufacturer: Eyekare Kilitch Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 travoprostin-t ophthalmic solution के बारे में (Hindi Summary)

उपयोग: यह दवा आंखों में बढ़े हुए दबाव को कम करने के लिए इस्तेमाल की जाती है, जिसे ओकुलर हाइपरटेंशन और ओपन-एंगल ग्लूकोमा कहा जाता है। यह आंखों में तरल पदार्थ के उत्पादन को कम करती है और उसके निकास को बढ़ाती है, जिससे आंखों का दबाव कम होता है और दृष्टि की रक्षा होती है। यह दवा केवल आंखों में डालने के लिए है और इसे निगलना नहीं चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में आंखों में जलन, लालिमा, धुंधली दृष्टि, और पलकों के बढ़ने की समस्या शामिल हैं। कुछ रोगियों में आंखों की पुतली का रंग बदल सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, धड़कन धीमी होना, या चक्कर आना महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को अपनी चिकित्सीय स्थिति के बारे में बताएं, खासकर यदि आपको अस्थमा, हृदय रोग, या मधुमेह है। कॉन्टैक्ट लेंस पहनने से पहले उन्हें निकाल लें और दवा डालने के 15 मिनट बाद ही वापस पहनें। दवा डालने के बाद आंख के भीतरी कोने को 1-2 मिनट तक दबाएं ताकि दवा शरीर में कम अवशोषित हो। दवा की बोतल की टिप को आंख या किसी सतह से न छुएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 travoprostin-t ophthalmic solution Uses & Benefits

[{"condition":"Open-angle glaucoma","description":"This medicine is used to reduce elevated intraocular pressure in patients with open-angle glaucoma when a single agent is insufficient.","evidence":"Well-established"},{"condition":"Ocular hypertension","description":"This medicine is indicated for the reduction of intraocular pressure in patients with ocular hypertension.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Angle-closure glaucoma","description":"May be used off-label in some cases of angle-closure glaucoma after definitive treatment, but evidence is limited.","evidence":"Limited"},{"condition":"Pediatric glaucoma","description":"Occasionally used off-label in children with glaucoma, but safety and efficacy are not well established.","evidence":"Limited"}]

Primary treatment for: Open-angle glaucoma

Also treats: Ocular hypertension

📋 Drug Information

Generic Name(s)Timolol (5mg) + Travoprost (40mcg)
Brand Nametravoprostin-t ophthalmic solution
ManufacturerEyekare Kilitch Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action Class
Route of AdministrationOphthalmic
StorageStore at room temperature between 15°C and 25°C. Protect from light and excessive heat. Keep the bottle tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Instruct patients to instill the drop in the evening to maximize the effect on nocturnal intraocular pressure.
2
Advise punctal occlusion after instillation to minimize systemic absorption and reduce the risk of systemic side effects.
3
Warn patients about the possibility of increased iris pigmentation and eyelash growth, which are usually reversible but may take time.
4
Monitor heart rate and blood pressure regularly, especially in patients with cardiovascular disease.
5
Caution patients not to stop the medication abruptly without consulting you, as this can lead to a sudden rise in intraocular pressure.
6
Remind patients to remove contact lenses before use and wait at least 15 minutes before reinserting them.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Elevated intraocular pressure
This medicine is commonly prescribed for this.
Likely Use
❌
Eye pain
This medicine is not a primary pain reliever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing topical ocular administration, timolol and travoprost are absorbed systemically through the nasolacrimal duct and conjunctiva. Systemic absorption of timolol can be significant, although it is reduced by punctal occlusion. Travoprost systemic absorption is relatively low.
DistributionTimolol is widely distributed in body tissues, including the eye. Travoprost is distributed primarily to the eye and surrounding tissues. Protein binding information for both agents is not established from the available information.
Protein BindingNot established from the available information.
MetabolismTimolol is metabolized in the liver primarily by the cytochrome P450 enzyme CYP2D6. Travoprost is metabolized in the eye and systemically by beta-oxidation and reduction.
Half-LifeThe elimination half-life of timolol is approximately 2.5 to 6 hours. The elimination half-life of travoprost is not established from the available information.
ExcretionTimolol and its metabolites are excreted primarily in the urine. Travoprost and its metabolites are excreted mainly in the urine and feces.
BioavailabilitySystemic bioavailability of timolol following ocular administration is approximately 50% to 70% of that achieved with oral dosing. Bioavailability of travoprost is not established from the available information.
Onset of ActionThe onset of intraocular pressure reduction is typically within 2 to 4 hours after instillation, with maximum effect observed after several weeks of regular use.
Peak Plasma TimePeak plasma concentration of timolol after ocular administration is reached in about 1 to 2 hours. Peak plasma time for travoprost is not established from the available information.
Duration of ActionThe intraocular pressure-lowering effect of this medicine lasts for approximately 24 hours, allowing for once-daily dosing.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Timolol is a non-selective beta-adrenergic receptor antagonist that reduces aqueous humor production by blocking beta receptors in the ciliary epithelium. Travoprost is a prostaglandin F2-alpha analogue that selectively binds to FP receptors, increasing aqueous humor outflow primarily through the uveoscleral pathway. Together, they effectively lower intraocular pressure by decreasing fluid production and enhancing fluid drainage.

Mechanism Steps

1
Timolol blocks beta-adrenergic receptors: Timolol binds to beta-1 and beta-2 adrenergic receptors in the ciliary body, reducing the production of aqueous humor.
2
Travoprost activates FP receptors: Travoprost binds to prostaglandin F receptors in the trabecular meshwork and ciliary muscle, increasing the outflow of aqueous humor via the uveoscleral pathway.
3
Combined reduction in intraocular pressure: The dual action of decreased production and increased outflow leads to a greater reduction in intraocular pressure than either agent alone.

💡 How to Take travoprostin-t ophthalmic solution

Strength: Timolol 5 mg/mL and travoprost 40 mcg/mL ophthalmic solution.

1Wash your hands thoroughly with soap and water.
2If you wear contact lenses, remove them before applying the drops.
3Shake the bottle gently before use.
4Tilt your head back and pull down your lower eyelid to form a small pocket.
5Look up and instill one drop into the pocket. Avoid touching the dropper tip to your eye or eyelid.
6Close your eye gently and press the inner corner of your eye near the nose for 1-2 minutes to reduce systemic absorption.
7Replace the cap tightly. Wash your hands again if needed.
8Wait at least 15 minutes before reinserting contact lenses.

Dosage Information

Adult DosageThe usual adult dose is one drop in the affected eye(s) once daily. The dose may be adjusted by your doctor based on your intraocular pressure response. Dose must be individualized by a qualified clinician based on indication, age, and clinical response.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustment is required for elderly patients, but caution is advised due to increased risk of systemic effects. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dosage adjustment is established for renal impairment. Consult your doctor.
Hepatic ImpairmentNo specific dosage adjustment is established for hepatic impairment. Consult your doctor.
Maximum Daily DoseOne drop in each affected eye once daily.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of travoprostin-t ophthalmic solution

✅ Common Side Effects

Eye burning or stinging (Common (5-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Eye redness (Common (5-10%))
May diminish over time. Consult doctor if it worsens.
Blurred vision (Common (5-10%))
Avoid driving or operating machinery until vision clears. If persistent, consult your doctor.
Increased eyelash growth (Common (5-10%))
This is a cosmetic effect that reverses upon discontinuation. Discuss with your doctor if concerned.
Headache (Uncommon (1-5%))
Usually resolves. If severe or persistent, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, or difficulty breathing.
Bradycardia or heart block (Rare (<0.1%))
Seek immediate medical attention if you experience slow heartbeat, dizziness, or fainting.
Bronchospasm (Rare (<0.1%))
Seek immediate medical attention if you experience wheezing, difficulty breathing, or chest tightness.
Severe eye infection or inflammation (Rare (<0.1%))
Consult your doctor immediately if you experience eye pain, swelling, or discharge.

⚠️ Rare Side Effects

Iris pigmentation changes
This is usually irreversible. Discuss with your doctor if you notice color changes in your eye.
Eyelid skin darkening
May reverse upon discontinuation. Consult your doctor if concerned.
Depression
Consult your doctor if you experience persistent low mood.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Oral beta-blockers Major
Calcium channel blockers Major
Digitalis Major
CYP2D6 inhibitors Moderate
Clonidine Moderate
NSAIDs Moderate
Other ophthalmic beta-blockers Minor
Adrenergic psychotropic drugs Minor

🚨 Major Interactions

  • Oral beta-blockers
  • Calcium channel blockers (e.g., verapamil, diltiazem)
  • Digitalis glycosides

⚡ Moderate Interactions

  • CYP2D6 inhibitors (e.g., quinidine, fluoxetine)
  • Clonidine
  • NSAIDs

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine and increase the risk of dizziness or fainting. It is advisable to limit or avoid alcohol while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to timolol, travoprost, or any component of the formulation","Bronchial asthma or a history of bronchial asthma","Severe chronic obstructive pulmonary disease","Sinus bradycardia, sinoatrial block, second or third degree atrioventricular block","Cardiogenic shock","Overt cardiac failure"]

⚠️ Warnings & Precautions

["For topical ophthalmic use only. Do not swallow.","Remove contact lenses before use and wait 15 minutes before reinsertion.","May cause blurred vision; avoid driving or operating machinery until vision is clear.","May increase pigmentation of the iris, eyelid skin, and eyelashes.","May cause systemic beta-blocking effects; monitor heart rate and blood pressure.","Use with caution in patients with diabetes, thyroid disorders, or myasthenia gravis.","Do not stop abruptly without consulting your doctor."]

🤱 Lactation Safety

It is not known whether this medicine is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a nursing woman. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its ophthalmic route. If accidental ingestion occurs, seek immediate medical attention. Symptoms of timolol overdose may include bradycardia, hypotension, bronchospasm, and heart failure. Treatment should be symptomatic and supportive.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you have a history of asthma, COPD, heart problems, diabetes, thyroid disorders, or any eye infections. Do not use this medicine if you have active eye inflammation or infection. Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them, as the preservative in this product may be absorbed by soft contact lenses. To reduce systemic absorption, gently press on the inner corner of your eye near the nose for one to two minutes after instilling the drops. Do not touch the dropper tip to your eye or any surface to avoid contamination. If you are using other eye drops, wait at least 5 to 10 minutes between applications. Do not stop using this medicine abruptly without consulting your doctor, as sudden discontinuation of timolol may worsen your condition. Keep this medicine out of reach of children. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to systemic side effects such as bradycardia and hypotension. Regular monitoring of heart rate and blood pressure is advised. Dose adjustment is not typically required, but caution is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this medicine during pregnancy has not been established. Your doctor may consider alternative treatments.

🏥 Post-Surgery Considerations

If you have undergone eye surgery, consult your doctor before using this medicine. It may need to be temporarily discontinued or adjusted based on your surgical procedure.

🦷 Dental Procedures

Inform your dentist that you are using this medicine, as it may interact with certain medications used during dental procedures. No specific precautions are typically required, but your dentist should be aware.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce overall health risks.
🥗
Regular eye check-ups are crucial for monitoring glaucoma.
😴
Avoid rubbing your eyes to prevent irritation.
💧
Wear sunglasses to protect your eyes from UV rays.
🧘
Follow a balanced diet rich in fruits and vegetables.
🌞
Get adequate sleep to support eye health.

🏋️ Exercise Considerations

Exercise is generally safe while using this medicine. However, if you experience dizziness or blurred vision after instilling the drops, avoid exercise until your vision is clear. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include foods rich in omega-3 fatty acids, such as fish and flaxseeds.
Reduce intake of processed foods and excess salt.
Stay well hydrated by drinking plenty of water.
Consume antioxidant-rich fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision after instillation. Avoid driving or operating heavy machinery until your vision is clear. Otherwise, it should not significantly impact your daily activities. Inform your employer if your work involves operating machinery.

🛑 When to Stop This Medicine

Do not stop using this medicine without consulting your doctor. Abrupt discontinuation can lead to a sudden increase in intraocular pressure and potential vision loss. If you experience severe side effects, contact your doctor immediately for guidance.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to increased pigmentation of the iris, eyelid skin, and eyelashes. These changes are usually reversible upon discontinuation but may take months to fade. Regular monitoring of intraocular pressure and optic nerve health is essential. Systemic effects such as bradycardia and hypotension may occur with prolonged use. Consult your doctor for regular check-ups.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Laser trabeculoplasty

A laser procedure that can improve fluid drainage from the eye.

Evidence: Well-established
Surgical trabeculectomy

A surgical procedure to create a new drainage pathway for aqueous humor.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions between this medicine and vaccines have been established. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-25°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. If crossing time zones, continue with your regular dosing schedule but consult your doctor for specific advice. Store at room temperature and protect from light. Check customs regulations for carrying prescription medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 60-year-old man with open-angle glaucoma
He was prescribed this medicine after his intraocular pressure remained high on a single agent. Within a month, his pressure dropped significantly. He experienced mild eye redness initially, which subsided. He emphasizes the importance of using the drop daily without missing doses.
💡 Lesson: Consistent daily use is key to controlling intraocular pressure and preventing vision loss.
👤 A 55-year-old woman with ocular hypertension
She started this medicine and noticed increased eyelash growth after a few months. Her doctor reassured her that this is a common and reversible effect. Her intraocular pressure is well controlled, and she has not experienced any serious side effects.
💡 Lesson: Cosmetic side effects like eyelash growth are common but manageable. Regular follow-up with your doctor is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering intraocular pressure within a few hours, but the full effect may take several weeks of regular use.

Q: Can I use this medicine if I wear contact lenses?

A: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them.

Q: What should I do if I miss a dose?

A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: There are no adequate studies in pregnant women. Consult your doctor if you are pregnant or planning to become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart rate?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for travoprostin-t ophthalmic solution

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used as needed for eye pressure.
    Fact: This medicine must be used regularly as prescribed to effectively lower intraocular pressure.
  • Myth: Once eye pressure is normal, the medicine can be stopped.
    Fact: Glaucoma is a chronic condition; stopping the medicine can lead to increased pressure and vision loss.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for individuals with certain lung or heart conditions. Consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Timolol and Travoprost ophthalmic solution

Brand Alternatives

  • Travacom

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","class":"Beta-blocker + Prostaglandin analogue","frequency":"Once daily","common_side_effects":"Eye redness, burning, increased eyelash growth"},{"medicine":"Latanoprost","class":"Prostaglandin analogue","frequency":"Once daily","common_side_effects":"Eye redness, increased eyelash growth"},{"medicine":"Timolol","class":"Beta-blocker","frequency":"Twice daily","common_side_effects":"Eye irritation, bradycardia"}]

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