brimoeye-t ophthalmic solution - Timolol (0.5% w/v) + Brimonidine (0.2% w/v) medicine

brimoeye-t ophthalmic solution

4.5 (11 reviews)
๐Ÿญ Eyekare Kilitch Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is brimoeye-t ophthalmic solution used for?

Abpress Eye Drop (Timolol + Brimonidine) is used to treat OPHTHAL. It contains Timolol (0.5% w/v) + Brimonidine (0.2% w/v), which Timolol reduces aqueous humor production by blocking beta-adrenergic receptors; . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Timolol + Brimonidine
  • Manufacturer: Eyekare Kilitch Limited
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š brimoeye-t ophthalmic solution Uses & Benefits

Reduction of intraocular pressure in open-angle glaucoma or ocular hypertension

Off-label uses: None commonly reported

๐Ÿ“‹ Drug Information

Generic Name(s)Timolol + Brimonidine
Brand NameAbpress Eye Drop
ManufacturerEyekare Kilitch Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassBeta-blocker + Alpha-2 adrenergic agonist
Route of AdministrationOphthalmic (topical)
StorageStore at 15-30ยฐC, protect from light, keep tightly closed
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSystemic absorption occurs through the nasolacrimal duct and conjunctiva
DistributionDistributes to various tissues including the eye
Protein BindingTimolol: ~60%; Brimonidine: ~29%
MetabolismTimolol: Hepatic (CYP2D6); Brimonidine: Hepatic (aldehyde oxidase)
Half-LifeTimolol: 4-6 hours; Brimonidine: 2-3 hours
ExcretionTimolol: Renal (20% unchanged); Brimonidine: Renal (70-80% unchanged)
BioavailabilityLow systemic bioavailability due to extensive first-pass metabolism
Onset of ActionTimolol: 30 minutes; Brimonidine: 1-2 hours
Peak Plasma TimeTimolol: 1-2 hours; Brimonidine: 1-4 hours
Duration of ActionTimolol: 12-24 hours; Brimonidine: 8-12 hours

How It Works

Timolol reduces aqueous humor production by blocking beta-adrenergic receptors; Brimonidine reduces aqueous humor production and increases uveoscleral outflow by stimulating alpha-2 adrenergic receptors

Mechanism Steps

1Timolol blocks beta-1 and beta-2 adrenergic receptors in the ciliary body, reducing aqueous humor production
2Brimonidine selectively stimulates alpha-2 adrenergic receptors, decreasing aqueous humor production and increasing uveoscleral outflow
3Combined effect results in significant reduction of intraocular pressure

๐Ÿ’ก How to Take brimoeye-t ophthalmic solution

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of brimoeye-t ophthalmic solution

โœ… Common Side Effects

  • Ocular burning/stinging
  • Blurred vision
  • Dry eye
  • Eye redness
  • Headache
  • Drowsiness

๐Ÿšจ Serious Side Effects

  • Bradycardia
  • Heart block
  • Bronchospasm
  • Hypotension
  • Syncope
  • Allergic reaction

โš ๏ธ Rare Side Effects

  • Depression
  • Insomnia
  • Corneal edema
  • Uveitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Beta-blockers (systemic) Major Additive bradycardia and hypotension
Calcium channel blockers Major Increased risk of heart block
Digoxin Major Increased risk of bradycardia
Clonidine Major Rebound hypertension on withdrawal
MAO inhibitors Major Hypertensive crisis
Antihypertensives Moderate Additive hypotensive effect
Antidiabetic agents Moderate Masking of hypoglycemia symptoms
Tricyclic antidepressants Moderate Reduced brimonidine efficacy
Corticosteroids Minor Possible increase in IOP
NSAIDs Minor Possible decrease in IOP-lowering effect

๐Ÿšจ Major Interactions

  • Beta-blockers (systemic)
  • Calcium channel blockers
  • Digoxin
  • Clonidine
  • MAO inhibitors

โšก Moderate Interactions

  • Antihypertensives
  • Antidiabetic agents
  • Tricyclic antidepressants

โ„น๏ธ Minor Interactions

  • Corticosteroids
  • NSAIDs

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

May enhance hypotensive effect

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Bronchial asthma, COPD, sinus bradycardia, second/third-degree AV block, cardiogenic shock, hypersensitivity to components

๐Ÿ“Š Monitoring Parameters

Intraocular pressure, heart rate, blood pressure, signs of ocular irritation

๐Ÿคฑ Lactation Safety

Not recommended; may be excreted in breast milk

๐Ÿ’Š Overdose Management

Supportive care; monitor heart rate and blood pressure; symptomatic treatment

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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