Brimofinet 5 mg/1.5 mg Eye Drop - Uses, Price, Side Effects
What is brimofinet 5 mg/1.5 mg eye drop used for?
Brimofinet 5 mg/1.5 mg Eye Drop is a combination of Timolol (a beta-blocker) and Brimonidine (an alpha-2 agonist) used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It works by reducing the production of aqueous humor and increasing its outflow, thereby protecting the optic nerve from damage.
- Generic Name: Timolol + Brimonidine
- Manufacturer: Calix Health Care
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ brimofinet 5 mg/1.5 mg eye drop Uses & Benefits
Reduction of intraocular pressure in open-angle glaucoma or ocular hypertension
Off-label uses: None commonly reported
๐ Drug Information
| Generic Name(s) | Timolol + Brimonidine |
| Brand Name | Abpress Eye Drop |
| Manufacturer | Calix Health Care |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Beta-blocker + Alpha-2 adrenergic agonist |
| Route of Administration | Ophthalmic (topical) |
| Storage | Store at 15-30ยฐC, protect from light, keep tightly closed |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Timolol reduces aqueous humor production by blocking beta-adrenergic receptors; Brimonidine reduces aqueous humor production and increases uveoscleral outflow by stimulating alpha-2 adrenergic receptors
Mechanism Steps
๐ก How to Take brimofinet 5 mg/1.5 mg eye drop
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of brimofinet 5 mg/1.5 mg eye drop
โ Common Side Effects
- Ocular burning/stinging
- Blurred vision
- Dry eye
- Eye redness
- Headache
- Drowsiness
๐จ Serious Side Effects
- Bradycardia
- Heart block
- Bronchospasm
- Hypotension
- Syncope
- Allergic reaction
โ ๏ธ Rare Side Effects
- Depression
- Insomnia
- Corneal edema
- Uveitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Beta-blockers (oral) | Moderate | Additive systemic beta-blockade |
| MAO inhibitors | Major | Hypertensive crisis |
| Digoxin | Moderate | Bradycardia |
๐จ Major Interactions
- Beta-blockers (systemic)
- Calcium channel blockers
- Digoxin
- Clonidine
- MAO inhibitors
โก Moderate Interactions
- Antihypertensives
- Antidiabetic agents
- Tricyclic antidepressants
โน๏ธ Minor Interactions
- Corticosteroids
- NSAIDs
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
May enhance hypotensive effect
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Bronchial asthma, COPD, sinus bradycardia, second/third-degree AV block, cardiogenic shock, hypersensitivity to components
๐ Monitoring Parameters
Intraocular pressure, heart rate, blood pressure, signs of ocular irritation
๐คฑ Lactation Safety
Not recommended; may be excreted in breast milk
๐ Overdose Management
Supportive care; monitor heart rate and blood pressure; symptomatic treatment
โฐ Missed Dose
Apply as soon as remembered; if near next dose, skip missed dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.