Axedol 100mg Injection (Tramadol): Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Slow, shallow, or difficulty breathing
- Seizures or convulsions
- Severe dizziness, confusion, or fainting
- Fast, irregular heartbeat
- Agitation, hallucinations, fever, or muscle twitching (serotonin syndrome)
- Swelling of face, lips, tongue, or throat
- Severe abdominal pain or vomiting
- Signs of withdrawal (anxiety, sweating, nausea, tremors) after stopping
If experiencing severe symptoms, call emergency services immediately.
What is Tramopact 100mg Injection used for?
This medicine is a tramadol injection used for moderate to severe pain. It works by blocking pain signals in the brain and spinal cord. It is given by a healthcare professional and is not for self-administration.
- Generic Name: Tramadol (100mg)
- Manufacturer: Avonic Life Sciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Tramopact 100mg Injection के बारे में (Hindi Summary)
उपयोग: यह दवा ट्रामाडोल 100 मिलीग्राम इंजेक्शन है, जिसका उपयोग मध्यम से गंभीर दर्द के इलाज के लिए किया जाता है। यह दर्द को कम करने के लिए मस्तिष्क और रीढ़ की हड्डी में दर्द के संकेतों को रोकती है। यह आमतौर पर सर्जरी के बाद, चोट लगने पर, या अन्य दर्दनाक स्थितियों में दी जाती है। यह दवा केवल एक योग्य स्वास्थ्य पेशेवर द्वारा इंजेक्शन के रूप में दी जाती है। इसे स्वयं न लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, चक्कर आना, नींद आना, सिरदर्द, कब्ज, मुंह सूखना और पसीना आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें सांस लेने में कठिनाई, दौरे, एलर्जी प्रतिक्रिया और निर्भरता शामिल हो सकती है। यदि आपको सांस लेने में तकलीफ, तेज धड़कन, भ्रम या दौरे पड़ें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल एक योग्य स्वास्थ्य पेशेवर द्वारा इंजेक्शन के रूप में दी जानी चाहिए। इसे स्वयं न लें। यदि आपको मिर्गी, गुर्दे या यकृत की बीमारी, सांस की समस्या या नशीली दवाओं के सेवन का इतिहास है तो अपने डॉक्टर को बताएं। इस दवा के साथ शराब का सेवन बिल्कुल न करें। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, वाहन न चलाएं। अपने डॉक्टर को सभी दवाओं के बारे में बताएं जो आप ले रहे हैं।
💊 Tramopact 100mg Injection Uses & Benefits
[{"condition":"Moderate to severe acute pain","description":"This medicine is used for short-term relief of moderate to severe pain, such as after surgery, trauma, or in acute medical conditions.","evidence":"Well-established"},{"condition":"Postoperative pain","description":"It is often used to manage pain following surgical procedures when oral analgesics are not sufficient or not tolerated.","evidence":"Well-established"},{"condition":"Chronic pain conditions","description":"In some cases, it may be used for chronic pain such as osteoarthritis or low back pain, but only under close medical supervision due to risk of dependence.","evidence":"Moderate"},{"condition":"Cancer pain","description":"It can be used as part of a pain management plan for cancer-related pain, though stronger opioids may be required.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Premature ejaculation","description":"Tramadol has been studied off-label for delaying ejaculation, but this is not a recommended use and should only be considered by a specialist.","evidence":"Limited"},{"condition":"Restless legs syndrome","description":"Some small studies suggest benefit, but it is not a standard treatment and carries risk of dependence.","evidence":"Limited"}]
Primary treatment for: Moderate to severe acute pain
Also treats: Postoperative pain, Chronic pain, Cancer pain
📋 Drug Information
| Generic Name(s) | Tramadol (100mg) |
| Brand Name | Tramopact 100mg Injection |
| Manufacturer | Avonic Life Sciences |
| Packaging / Form | vial of 2 ml Injection (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Parenteral (intramuscular or intravenous injection) |
| Storage | Store below 30°C in a dry place, protected from light. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to mu-opioid receptors in the central nervous system, which reduces the transmission of pain signals. It also inhibits the reuptake of norepinephrine and serotonin, neurotransmitters involved in pain modulation. This dual action makes it effective for moderate to severe pain. The opioid effect is mainly responsible for the analgesic action, while the monoamine reuptake inhibition contributes to additional pain relief and may affect mood.
Mechanism Steps
💡 How to Take Tramopact 100mg Injection
Strength: Injection: 100 mg in 2 mL (50 mg/mL)
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 50 to 100 mg administered intramuscularly or intravenously every 4 to 6 hours as needed for pain. The maximum recommended daily dose is 400 mg. For intravenous administration, the dose may be given slowly over 2 to 3 minutes. In patients with renal or hepatic impairment, the dose should be reduced. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is contraindicated in children under 12 years and in children under 18 years following tonsillectomy and/or adenoidectomy. |
| Elderly Dosage | In elderly patients (above 65 years), the dose should be reduced due to decreased renal and hepatic function. The maximum daily dose should not exceed 300 mg. Use with caution and monitor closely for side effects. |
| Renal Impairment | In patients with renal impairment, the dose should be adjusted. For creatinine clearance less than 30 mL/min, the dosing interval should be increased to every 12 hours, and the maximum daily dose should not exceed 200 mg. For severe renal impairment, use is not recommended. |
| Hepatic Impairment | In patients with hepatic impairment, the dose should be reduced. For severe hepatic impairment, tramadol is contraindicated. For moderate impairment, the dosing interval should be increased, and the maximum daily dose should not exceed 200 mg. |
| Maximum Daily Dose | 400 mg per day for adults with normal renal and hepatic function. Reduced in elderly and those with renal or hepatic impairment. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Tramopact 100mg Injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| SSRIs/SNRIs | Major | |
| Benzodiazepines | Major | |
| Warfarin | Major | |
| Carbamazepine | Moderate | |
| Quinidine | Moderate | |
| Cimetidine | Moderate | |
| Alcohol | Major |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- SSRIs, SNRIs, tricyclic antidepressants
- CNS depressants (e.g., benzodiazepines, alcohol, opioids)
- Warfarin
⚡ Moderate Interactions
- Carbamazepine
- Quinidine
- Cimetidine
🍷 Alcohol Interaction
Alcohol should be completely avoided while receiving this medicine. Combining alcohol with tramadol can cause severe drowsiness, respiratory depression, coma, and even death. It also increases the risk of seizures and liver toxicity.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to tramadol or any component of the formulation","Severe respiratory depression or acute severe asthma","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of MAOI discontinuation","Severe hepatic or renal impairment","Children under 12 years of age","Post-operative pain management in children under 18 years following tonsillectomy and/or adenoidectomy","Known or suspected gastrointestinal obstruction, including paralytic ileus","Acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids, or psychotropic drugs"]
⚠️ Warnings & Precautions
["This medicine can cause respiratory depression, especially in the elderly or those with compromised respiratory function. Monitor closely.","Seizures have been reported in patients taking tramadol, particularly those with a history of epilepsy or taking other seizure-threshold-lowering drugs.","Serotonin syndrome can occur, especially with concomitant use of serotonergic drugs. Monitor for symptoms.","Tramadol has a potential for abuse and dependence. Use with caution in patients with a history of substance abuse.","Do not use in children under 12 years. Avoid in children under 18 for tonsillectomy/adenoidectomy pain.","Use with caution in patients with head injury, increased intracranial pressure, or impaired consciousness.","May impair mental and physical abilities required for driving or operating machinery.","Avoid abrupt discontinuation to prevent withdrawal symptoms."]
🤱 Lactation Safety
Tramadol passes into breast milk and may cause serious side effects in a nursing infant, including excessive sleepiness, difficulty breathing, and poor feeding. It is not recommended during breastfeeding. If use is essential, monitor the infant closely and consult a doctor.
💊 Overdose Management
Overdose of this medicine can cause respiratory depression, seizures, coma, and cardiac arrest. Seek emergency medical attention immediately. Treatment includes supportive care, maintenance of airway and ventilation, and administration of naloxone (an opioid antagonist) for respiratory depression. Seizures may be managed with benzodiazepines. Hemodialysis may be considered in severe cases.
⏰ Missed Dose
Since this medicine is usually given by a healthcare professional in a hospital or clinic setting, missed doses are unlikely. If you miss a scheduled dose, contact your healthcare provider for instructions. Do not attempt to self-administer an extra dose.
Additional Safety Advice
This medicine must only be given by a qualified healthcare professional as an intramuscular or intravenous injection. Do not attempt to self-administer. Inform your doctor if you have a history of epilepsy, kidney or liver disease, breathing problems, or substance abuse. Avoid alcohol completely while receiving this medicine, as it increases the risk of serious side effects. Do not drive or operate heavy machinery until you know how this medicine affects you. Tell your doctor about all other medicines you are taking, especially antidepressants, antipsychotics, and blood thinners. Do not stop this medicine abruptly without medical advice, as withdrawal symptoms may occur. Keep all follow-up appointments and report any new or worsening symptoms promptly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of this medicine, especially respiratory depression and drowsiness. The dose should be reduced, and the maximum daily dose should not exceed 300 mg. Close monitoring is required.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It is not recommended during pregnancy unless clearly needed. Prolonged use can lead to neonatal withdrawal syndrome.
🏥 Post-Surgery Considerations
This medicine is often used for postoperative pain. It should be administered by a healthcare professional. Monitor for respiratory depression and other side effects. Do not use for pain after tonsillectomy or adenoidectomy in children under 18 years.
🦷 Dental Procedures
This medicine may be used for pain management after dental procedures, but it should only be given by a healthcare professional. Inform your dentist if you are taking this medicine before any dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that require mental alertness until you know how this medicine affects you. This medicine can cause drowsiness and dizziness, which may increase the risk of injury during exercise. Consult your doctor before resuming any exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and difficulty concentrating, which may affect your ability to work or perform daily activities. Do not drive or operate machinery until you know how it affects you. Inform your employer if your job requires alertness. Your doctor may advise rest during treatment.
🛑 When to Stop This Medicine
Do not stop this medicine abruptly without consulting your doctor, as withdrawal symptoms may occur. Your doctor will gradually reduce the dose if needed. If you experience severe side effects or signs of an allergic reaction, seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to tolerance, dependence, and withdrawal symptoms. It may also cause hormonal changes, sexual dysfunction, and increased sensitivity to pain (hyperalgesia). Regular monitoring by a healthcare provider is essential. Do not use for prolonged periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Medicines like paracetamol or NSAIDs may be used for mild to moderate pain.
Evidence: Well-establishedCan complement medicine for chronic pain management.
Evidence: Well-establishedTargeted injections to block pain signals for specific conditions.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider that you are receiving this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use if solution is discolored or contains particles
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Since it is an injectable opioid, check the laws of your destination country regarding controlled substances. Store it at room temperature, away from direct sunlight and moisture. If traveling across time zones, consult your doctor for any adjustments to your dosing schedule. Never pack it in checked luggage; keep it in your carry-on with proper documentation.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts relieving pain within 10 to 15 minutes after intravenous injection and within 30 to 60 minutes after intramuscular injection.
A: The pain relief typically lasts for 4 to 6 hours after a single dose.
A: No, this medicine must be given by a qualified healthcare professional in a medical setting.
A: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor.
A: Since it is given by a healthcare professional, missed doses are unlikely. If you miss a scheduled dose, contact your healthcare provider.
🤔 Common Patient Concerns
🔄 Substitutes for Tramopact 100mg Injection
View AllAlternative brands with exact same active ingredient:
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Simol 50mg Injectionsavoy Biotech ₹2.31 89.7% CHEAPER
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stayhappi tramadol 100mg injectionSarvagunaushdhi Pvt Ltd ₹6.25 72.2% CHEAPER
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Tramasafe 100mg InjectionS R Pharmaceuticals ₹11.37 49.5% CHEAPER
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bardol 100mg injectionBharti Life Sciences ₹15.62 30.6% CHEAPER
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xaio t 100mg injectionIndo-Asia Pharma Care ₹16.88 25% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Tramadol is a safe painkiller with no addiction risk.
Fact: Tramadol is an opioid and carries a risk of dependence and withdrawal, especially with prolonged use. - Myth: Tramadol injection can be self-administered at home.
Fact: This medicine must only be given by a qualified healthcare professional in a medical setting. - Myth: Tramadol is safe to use during pregnancy.
Fact: Tramadol is not recommended during pregnancy as it may harm the unborn baby.
🔄 Alternative Options
Generic Alternatives
- Tramadol 100mg injection
Brand Alternatives
- Axedol 100mg injection