Brilinta 90mg Tablet (Ticagrelor): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Black, tarry stools or blood in the stool
- Vomiting blood or material that looks like coffee grounds
- Severe headache, confusion, or weakness on one side of the body
- Bleeding that will not stop after applying pressure
- Sudden swelling of the face, lips, or throat, or difficulty breathing
- Yellowing of the skin or eyes, or dark urine
- Very slow or irregular heartbeat, or fainting
- Unusual bruising or tiny red spots on the skin
- Chest pain that is new or worsening
- Severe abdominal pain or back pain
If experiencing severe symptoms, call emergency services immediately.
What is Ticamine 90mg Tablet used for?
This medicine is a prescription blood thinner containing ticagrelor 90 mg. It is used with aspirin to prevent heart attacks, strokes, and blood clots in people who have had a heart attack, unstable angina, or a coronary stent. It works by stopping platelets from sticking together. It is taken twice daily, with or without food. Do not stop it without your doctor's advice.
- Generic Name: Ticagrelor (90mg)
- Manufacturer: Shinto Organics (P) Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Ticamine 90mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टिकैग्रेलोर 90 मिलीग्राम की बनी है और इसे खून पतला करने वाली दवा कहा जाता है। यह दिल के दौरे, अस्थिर एनजाइना और दिल की धमनियों में स्टेंट डालने के बाद खून के थक्के बनने से रोकने के लिए इस्तेमाल की जाती है। यह दवा खून में मौजूद प्लेटलेट्स को आपस में चिपकने से रोकती है, जिससे दिल की धमनियों में थक्का नहीं बनता। यह दवा हमेशा एस्पिरिन की कम खुराक (75-100 मिलीग्राम) के साथ ली जाती है। इसे डॉक्टर के बताए अनुसार दिन में दो बार लें। इस दवा को अपने आप बंद न करें, क्योंकि अचानक बंद करने से दिल का दौरा या स्टेंट में थक्का बन सकता है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में खून बहना, आसानी से चोट लगना, नाक से खून आना, मसूड़ों से खून आना, सिरदर्द, सांस फूलना, चक्कर आना, जी मिचलाना और दस्त शामिल हैं। सांस फूलना इस दवा का एक ज्ञात दुष्प्रभाव है, जो आमतौर पर हल्का होता है और समय के साथ ठीक हो जाता है। गंभीर दुष्प्रभावों में पेट, आंत या दिमाग में गंभीर रक्तस्राव, धीमी हृदय गति और एक दुर्लभ रक्त विकार शामिल हैं। अगर आपको काला मल, खून की उल्टी, गंभीर सिरदर्द या असामान्य खून बहना दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर 90 मिलीग्राम की एक गोली दिन में दो बार, खाने के साथ या बिना खाने के। गोली को चबाएं या तोड़ें नहीं। अपनी एस्पिरिन की खुराक भी नियमित रूप से लें। कोई भी सर्जरी, दांत का इलाज या प्रक्रिया से पहले अपने डॉक्टर और दंत चिकित्सक को इस दवा के बारे में जरूर बताएं। बिना डॉक्टर की सलाह के कोई अन्य दर्द निवारक दवा, खून पतला करने वाली दवा या हर्बल सप्लीमेंट न लें। अगर आपको चोट लगने या खून बहने की समस्या हो तो तुरंत डॉक्टर से संपर्क करें। इस दवा को बच्चों की पहुंच से दूर, ठंडी और सूखी जगह पर रखें।
💊 Ticamine 90mg Tablet Uses & Benefits
[{"condition":"Acute coronary syndrome (heart attack or unstable angina)","description":"This medicine is used with aspirin to reduce the risk of heart attack, stroke, and death in patients who have had a heart attack or unstable angina.","evidence":"Well-established"},{"condition":"Prevention of stent thrombosis after percutaneous coronary intervention (PCI)","description":"This medicine is used with aspirin to prevent blood clots from forming inside a coronary stent placed during angioplasty.","evidence":"Well-established"},{"condition":"Secondary prevention after myocardial infarction","description":"This medicine is used long-term with aspirin to lower the risk of another heart attack or cardiovascular death in patients who have had a heart attack.","evidence":"Well-established"},{"condition":"High-risk transient ischemic attack or minor stroke","description":"This medicine may be used in some patients with a recent minor stroke or high-risk TIA to prevent a subsequent stroke, as determined by a specialist.","evidence":"Emerging evidence"}]
Off-label uses: [{"condition":"Peripheral arterial disease","description":"Sometimes considered by specialists for reducing cardiovascular events in patients with peripheral arterial disease, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Coronary artery disease with high bleeding risk","description":"In selected patients who cannot tolerate other antiplatelet medicines, this medicine may be considered off-label, but the decision must be made by a cardiologist.","evidence":"Limited"}]
Primary treatment for: Acute coronary syndrome (heart attack or unstable angina)
Also treats: Coronary artery disease with stent placement, Prior myocardial infarction, High-risk transient ischemic attack or minor stroke
📋 Drug Information
| Generic Name(s) | Ticagrelor (90mg) |
| Brand Name | Ticamine 90mg Tablet |
| Manufacturer | Shinto Organics (P) Limited |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C (59°F to 86°F). Keep it in its original container, tightly closed, and protect it from moisture and heat. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | The shelf life is typically 24 to 36 months from the date of manufacture. Check the expiry date on the pack. Do not use after the expiry date. |
| WHO Guideline | The World Health Organization does not issue specific treatment guidelines for ticagrelor. However, major cardiology societies recommend ticagrelor as a first-line antiplatelet medicine for acute coronary syndrome. Always follow your local guidelines and your doctor's advice. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) does not have a specific guideline for ticagrelor alone. Indian cardiology societies generally follow international guidelines for acute coronary syndrome, which include ticagrelor as a preferred P2Y12 inhibitor. Consult your cardiologist for personalized advice. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking a specific receptor on platelets called the P2Y12 receptor. Platelets are tiny blood cells that help form clots. When this medicine binds to the P2Y12 receptor, it stops adenosine diphosphate (ADP) from activating the platelets. Because the blocking is reversible, platelet function returns gradually after the medicine is stopped. This action prevents platelets from clumping together and forming clots inside blood vessels, especially in the heart after a heart attack or stent placement. Unlike some other antiplatelet medicines, this medicine does not need to be activated by the liver, so it works quickly after you take it.
Mechanism Steps
💡 How to Take Ticamine 90mg Tablet
Strength: This medicine is available as a 90 mg immediate-release film-coated tablet for oral use.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 90 mg taken orally twice daily, with or without food. For patients with acute coronary syndrome, a loading dose of 180 mg (two 90 mg tablets) is often given as soon as possible, followed by 90 mg twice daily. This medicine is usually taken together with low-dose aspirin (75-100 mg daily). The duration of treatment depends on your condition and whether you have a stent. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and bleeding risk. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (65 years and older) may be at higher risk of bleeding. No specific dose adjustment is recommended based on age alone, but your doctor will consider your overall health, kidney and liver function, and bleeding risk. Use with caution and monitor closely. |
| Renal Impairment | No dose adjustment is needed for patients with mild to moderate kidney problems. This medicine has not been studied in patients with severe kidney disease or those on dialysis. Use with caution in these patients and discuss with your doctor. |
| Hepatic Impairment | No dose adjustment is needed for patients with mild liver impairment. This medicine is not recommended for patients with moderate to severe liver impairment because it has not been studied in these patients and may increase the risk of bleeding. |
| Maximum Daily Dose | The maximum recommended daily dose is 180 mg (90 mg twice daily). A loading dose of 180 mg may be given once at the start of treatment, but this is not repeated daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Ticamine 90mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Clarithromycin | Major | |
| Rifampin | Major | |
| Warfarin | Major | |
| Ibuprofen | Major | |
| Clopidogrel | Major | |
| Diltiazem | Moderate | |
| Digoxin | Moderate | |
| Simvastatin | Moderate | |
| Fluoxetine | Moderate |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir)
- Strong CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
- Other antiplatelet medicines (e.g., clopidogrel, prasugrel, dipyridamole)
- Anticoagulants (e.g., warfarin, apixaban, rivaroxaban)
- NSAIDs (e.g., ibuprofen, naproxen, diclofenac)
⚡ Moderate Interactions
- Moderate CYP3A4 inhibitors (e.g., diltiazem, verapamil, erythromycin)
- Digoxin
- Simvastatin, lovastatin
- SSRIs (e.g., fluoxetine, sertraline)
🍷 Alcohol Interaction
Alcohol can increase the risk of stomach bleeding and may worsen dizziness or liver problems while taking this medicine. It is best to avoid alcohol or limit it to very small amounts. Talk to your doctor about safe alcohol use.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active pathological bleeding, such as a bleeding peptic ulcer or bleeding in the brain","History of intracranial hemorrhage (bleeding in the brain)","Severe liver impairment","Hypersensitivity or allergy to ticagrelor or any ingredient in the tablet","Concomitant use with strong CYP3A4 inhibitors that significantly increase ticagrelor levels"]
⚠️ Warnings & Precautions
["This medicine increases the risk of bleeding. Tell your doctor if you have a history of bleeding problems.","Do not stop taking this medicine without talking to your doctor, as stopping suddenly can increase the risk of heart attack or stent thrombosis.","Shortness of breath is a common side effect. It usually improves over time, but tell your doctor if it is severe.","This medicine can cause dizziness. Avoid driving or operating heavy machinery until you know how it affects you.","Before any surgery or dental procedure, tell your doctor or dentist that you are taking this medicine. You may need to stop it temporarily.","This medicine may interact with many other medicines. Always tell your doctor about all medicines, supplements, and herbal products you take.","Avoid grapefruit and grapefruit juice while taking this medicine.","This medicine is not recommended for patients with severe liver disease.","Use with caution in elderly patients, as they may be more prone to bleeding.","This medicine may increase uric acid levels and trigger gout attacks."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because of the potential for serious side effects in a breastfed infant, breastfeeding is not recommended while taking this medicine. Discuss with your doctor about alternative feeding options.
💊 Overdose Management
Overdose of this medicine can cause excessive bleeding. There is no specific antidote. If you suspect an overdose, seek emergency medical care immediately. Treatment is supportive, which may include stopping the medicine, giving blood transfusions or platelet transfusions if bleeding is severe, and other measures as needed. Do not try to vomit or take any other medicine without medical advice.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, call your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as your doctor prescribes, usually one 90 mg tablet twice daily with or without food. Do not crush, chew, or split the tablet unless your doctor tells you to. Always take your low-dose aspirin as directed along with this medicine. Tell all your doctors and your dentist that you are taking this medicine before any surgery, dental work, or procedure. Avoid activities that can cause injury or bleeding, such as contact sports. Do not take other blood thinners, NSAID pain relievers like ibuprofen or naproxen, or herbal supplements without asking your doctor first. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue your regular schedule. Never double the dose. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (65 years and older) may have a higher risk of bleeding while taking this medicine. They may also be more sensitive to side effects like dizziness and shortness of breath. Your doctor will monitor you closely and may adjust other medicines to reduce bleeding risk. Falls should be avoided, as they can lead to serious bleeding. Regular check-ups are important.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before conception. This medicine may increase the risk of bleeding during pregnancy and delivery. Your doctor may switch you to a different medicine or adjust your treatment. Use effective contraception while taking this medicine unless your doctor advises otherwise. If you become pregnant while taking this medicine, contact your doctor immediately.
🏥 Post-Surgery Considerations
After surgery, your doctor will decide when it is safe to restart this medicine. Because it increases bleeding risk, it is often stopped several days before surgery. Do not restart it on your own. Follow your surgeon's and cardiologist's instructions carefully. If you have a stent, stopping this medicine even for a short time can increase the risk of stent thrombosis, so your doctors will coordinate your care.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure, including cleanings, extractions, or implants. Your dentist may recommend stopping the medicine for a few days before the procedure to reduce bleeding risk. However, do not stop it without consulting your cardiologist, especially if you have a recent stent. Your dentist may use extra measures to control bleeding during the procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is good for your heart, but because this medicine increases bleeding risk, avoid activities that can cause falls or injuries, such as contact sports, heavy lifting, or high-impact activities. Walking, swimming, and cycling are generally safe. If you experience shortness of breath during exercise, stop and rest. Talk to your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or shortness of breath in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work and daily activities, but you should avoid jobs that involve a high risk of injury or bleeding. If your work involves physical labor, talk to your doctor about precautions. You may need to take time off work after a heart attack or stent placement, but this medicine itself does not usually prevent you from returning to work.
🛑 When to Stop This Medicine
Do not stop taking this medicine without talking to your doctor. Stopping suddenly can increase your risk of heart attack, stent thrombosis, or death. Your doctor may stop the medicine before surgery or if you develop serious bleeding. If you experience severe side effects, contact your doctor immediately. They will decide whether to adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for preventing heart attacks and strokes in patients with acute coronary syndrome. The main risk is bleeding, which can occur at any time. Your doctor will monitor you for signs of bleeding and may check your blood counts periodically. Long-term use may also increase uric acid levels and trigger gout in some patients. Do not stop the medicine without your doctor's advice, as the risk of heart attack or stent thrombosis increases after stopping. Regular follow-up with your cardiologist is important.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another antiplatelet medicine that may be used if you cannot tolerate ticagrelor. It is taken once daily but has a slower onset.
Evidence: Well-establishedA more potent antiplatelet medicine taken once daily. It may be an option for some patients but has a higher bleeding risk.
Evidence: Well-establishedIn some patients who cannot take P2Y12 inhibitors, aspirin alone may be used, but it is less effective than dual antiplatelet therapy.
Evidence: Well-establishedHeart-healthy diet, exercise, smoking cessation, and stress management can complement medicine and improve outcomes.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, because it increases bleeding risk, injections should be given with caution. Inform the healthcare provider that you are taking this medicine before receiving any vaccine. Flu and pneumonia vaccines are recommended for heart patients, but discuss timing with your doctor.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in the original container with the lid tightly closed
❌ DON'T
Do not transfer to another container
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom
✅ DO
Keep out of reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription and a doctor's note explaining that you need this medicine. Keep it in your carry-on luggage, not in checked baggage. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, adjust your dosing schedule gradually, but try to keep doses about 12 hours apart. Do not stop taking the medicine during travel. Check the laws of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 minutes to 2 hours after a loading dose. Maximum effect is seen within 2 to 4 hours.
A: The duration depends on your condition. After a heart attack, it is often taken for at least 12 months. If you have a stent, it may be longer. Follow your doctor's advice.
A: No. Stopping this medicine suddenly can increase your risk of heart attack, stent thrombosis, or death. Always talk to your doctor before stopping.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double the dose.
A: Avoid NSAIDs like ibuprofen and naproxen, as they increase bleeding risk. Acetaminophen is generally safer for pain. Always check with your doctor.
A: This medicine should be used during pregnancy only if clearly needed. Talk to your doctor about the risks and benefits.
A: Alcohol can increase the risk of stomach bleeding and dizziness. It is best to avoid or limit alcohol while taking this medicine.
A: Tell your dentist you are taking this medicine. They may recommend stopping it for a few days before a procedure to reduce bleeding risk. Do not stop without medical advice.
🤔 Common Patient Concerns
🔄 Substitutes for Ticamine 90mg Tablet
View AllAlternative brands with exact same active ingredient:
-
Ticasave TabletEris Lifesciences Ltd ₹142.80 31.1% CHEAPER
-
ticapol tabletMedipol Pharmaceuticals India Pvt Ltd ₹170.00 17.9% CHEAPER
-
tikacad 90 tabletCadila Pharmaceuticals Ltd ₹186.00 10.2% CHEAPER
-
ticagat tabletNatco Pharma Ltd ₹239.00 15.4% COSTLIER
-
brigrel tabletMicro Labs Ltd ₹240.00 15.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller.
Fact: This medicine is not a painkiller. It is a blood thinner used to prevent heart attacks and strokes. - Myth: I can stop this medicine once I feel better.
Fact: You must not stop this medicine without talking to your doctor. Stopping suddenly can cause a heart attack or stent blockage. - Myth: This medicine can be taken with any other medicine.
Fact: This medicine interacts with many medicines, including pain relievers, antibiotics, and antidepressants. Always check with your doctor or pharmacist. - Myth: This medicine is safe during pregnancy.
Fact: This medicine should be used during pregnancy only if clearly needed. Talk to your doctor about safer options. - Myth: I can drink alcohol while taking this medicine.
Fact: Alcohol can increase the risk of stomach bleeding and dizziness. It is best to avoid or limit alcohol.
🔄 Alternative Options
Generic Alternatives
- Ticagrelor 90 mg tablet
Brand Alternatives
- Brilinta 90 mg tablet