acecaine oral gel - Oxetacaine (10mg/5ml) + Aluminium Hydroxide (0.291mg/5ml) medicine

Acicaine Oral Gel: Complete Medicine Guide

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🏭 Shinto Organics (P) Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for local anaesthetic and antacid effects.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of the face, lips, or throat
  • Severe abdominal pain
  • Blood in vomit or stool
  • Signs of electrolyte imbalance (muscle cramps, weakness, irregular heartbeat)
  • Persistent vomiting
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is acecaine oral gel used for?

This medicine is an oral gel combining oxetacaine (a local anaesthetic) and aluminium hydroxide (an antacid). It is used to relieve pain and discomfort in the mouth, throat, and upper gastrointestinal tract, and to neutralise excess stomach acid.

  • Generic Name: Oxetacaine + Aluminium Hydroxide
  • Manufacturer: Shinto Organics (P) Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 acecaine oral gel के बारे में (Hindi Summary)

उपयोग: यह दवा मुँह के छालों, गले की खराश और एसिड रिफ्लक्स (जीईआरडी) से राहत दिलाने के लिए इस्तेमाल की जाती है। इसमें ऑक्सेटाकेन नामक स्थानीय एनेस्थेटिक और एल्युमिनियम हाइड्रॉक्साइड नामक एंटासिड होता है। ऑक्सेटाकेन दर्द वाले हिस्से को सुन्न करता है, जबकि एल्युमिनियम हाइड्रॉक्साइड पेट के एसिड को बेअसर करता है। यह दवा खाने के बाद और सोने से पहले ली जा सकती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह या गले में हल्की सुन्नता, चॉकी स्वाद और कभी-कभी जी मिचलाना शामिल है। ये आमतौर पर अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी प्रतिक्रिया जैसे दाने, खुजली, चेहरे या गले में सूजन हो सकती है। ऐसा होने पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को गर्भावस्था, स्तनपान या किसी अन्य दवा के बारे में बताएं। दवा लेने के 30 मिनट तक कुछ न खाएं-पिएं। अन्य दवाओं, विशेषकर एंटीबायोटिक्स के साथ 2 घंटे का अंतराल रखें। बिना डॉक्टर की सलाह के 2 सप्ताह से अधिक इसका उपयोग न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 acecaine oral gel Uses & Benefits

[{"condition":"Mouth ulcers","description":"Provides local anaesthetic and antacid relief for painful mouth ulcers.","evidence":"Well-established"},{"condition":"Sore throat","description":"Soothes throat irritation and pain due to infections or other causes.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"Helps relieve heartburn and acid regurgitation by neutralising stomach acid.","evidence":"Well-established"},{"condition":"Pre-procedural numbing","description":"Used before endoscopy or other throat procedures to numb the area.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Dyspepsia","description":"Sometimes used for general indigestion, though not a primary indication.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease (GERD)

Also treats: Mouth ulcers, Sore throat, Dyspepsia

📋 Drug Information

Generic Name(s)Oxetacaine + Aluminium Hydroxide
Brand NameAcicaine Oral Gel
ManufacturerShinto Organics (P) Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntacid + Local Anesthetic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine after meals and at bedtime for best results.
2
Avoid eating or drinking for at least 30 minutes after taking this medicine.
3
Separate this medicine from other medications by at least 2 hours to prevent interactions.
4
Do not use this medicine for more than 2 weeks without consulting your doctor.
5
If you experience numbness in the mouth, avoid hot foods and drinks until sensation returns.
6
Report any signs of allergic reaction immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Mouth ulcers
This medicine is commonly prescribed for this.
Likely Use
Sore throat
This medicine can provide relief.
Likely Use
Heartburn
This medicine helps neutralise acid.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOxetacaine is poorly absorbed from the gastrointestinal tract; its action is primarily local. Aluminium hydroxide is minimally absorbed; most remains in the gut and is excreted in faeces.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionAluminium hydroxide is primarily excreted in faeces. Oxetacaine is likely metabolised locally and excreted in urine, but specific data are not available.
BioavailabilityNot established from the available information.
Onset of ActionOxetacaine provides local anaesthesia within a few minutes of application. Aluminium hydroxide begins neutralising acid immediately upon contact.
Peak Plasma TimeNot established from the available information.
Duration of ActionLocal anaesthetic effect lasts approximately 20-30 minutes. Antacid effect lasts until the neutralised acid is emptied from the stomach, typically 1-2 hours.

How It Works

This medicine combines two active ingredients. Oxetacaine is a local anaesthetic that blocks sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses, thereby numbing the area. Aluminium hydroxide is an antacid that neutralises gastric acid by reacting with hydrochloric acid to form aluminium chloride and water, reducing acidity and soothing irritation.

Mechanism Steps

1
Sodium channel blockade by oxetacaine: Oxetacaine binds to voltage-gated sodium channels on nerve endings, preventing depolarisation and blocking pain signal transmission.
2
Acid neutralisation by aluminium hydroxide: Aluminium hydroxide reacts with hydrochloric acid in the stomach to form aluminium chloride and water, raising the pH and reducing acidity.
3
Combined effect: The local anaesthetic action provides rapid pain relief, while the antacid reduces acid irritation, promoting comfort and healing.

💡 How to Take acecaine oral gel

Strength: Oral gel containing Oxetacaine 10mg/5ml and Aluminium Hydroxide 0.291mg/5ml.

1Shake the bottle well before use.
2Measure the prescribed dose using the measuring cup or spoon provided.
3Swallow the gel slowly; do not chew or rinse mouth immediately.
4Avoid eating or drinking for at least 30 minutes after taking.
5Take at regular intervals as advised by your doctor.

Dosage Information

Adult DosageThe usual adult dose is 5-10 mL of the gel taken orally, up to four times daily, preferably after meals and at bedtime. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Consult a doctor.
Renal ImpairmentUse with caution in renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentNo specific dose adjustment established. Consult a doctor.
Maximum Daily DoseNot established from the available information. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take after meals
Enhances antacid effect and reduces stomach upset.
Any food or drink
Avoid for 30 minutes after taking
Prevents washing away of medicine.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of acecaine oral gel

✅ Common Side Effects

Mild numbness of mouth or throat (Common (5-10%))
Usually resolves on its own. Avoid hot foods and drinks until sensation returns.
Chalky taste (Common (5-10%))
Rinse mouth with water if unpleasant. This is harmless.
Nausea (Uncommon (1-5%))
Take with food or milk to reduce nausea. Consult doctor if persistent.

🚨 Serious Side Effects

Allergic reactions (rash, itching, swelling, difficulty breathing) (Rare (<0.1%))
Seek immediate medical attention.
Constipation (due to aluminium hydroxide) (Uncommon (1-5%))
Increase fluid and fibre intake. Consult doctor if severe.
Electrolyte imbalance (with prolonged high-dose use) (Rare (<0.1%))
Consult doctor for monitoring if long-term use.

⚠️ Rare Side Effects

Metallic taste
Usually resolves. Chew sugar-free gum if bothersome.
Headache
Rest and hydrate. Consult doctor if severe.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tetracycline Major
Ciprofloxacin Major
Iron supplements Moderate
Levothyroxine Moderate

🚨 Major Interactions

  • Tetracycline antibiotics
  • Fluoroquinolone antibiotics

⚡ Moderate Interactions

  • Iron supplements
  • Levothyroxine

🍷 Alcohol Interaction

Alcohol may increase stomach irritation and worsen the condition being treated. It is advisable to avoid alcohol while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to oxetacaine or aluminium hydroxide","Severe renal impairment","Hypophosphatemia"]

⚠️ Warnings & Precautions

["Do not exceed recommended dose.","Avoid use in children under 12 years without medical advice.","Use with caution in elderly patients with renal impairment.","May interfere with absorption of other medications; separate administration times.","Do not use for prolonged periods without medical supervision."]

🤱 Lactation Safety

It is not known whether oxetacaine or aluminium hydroxide pass into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose is unlikely due to limited systemic absorption. In case of accidental overdose, seek medical attention. Symptoms may include gastrointestinal discomfort. Treatment is supportive.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not exceed the recommended dose. Avoid eating or drinking for at least 30 minutes after taking this medicine to allow it to work effectively. If you are taking other medications, especially antibiotics like tetracyclines or fluoroquinolones, separate them by at least 2 hours from this medicine to prevent interactions. Do not use this medicine for more than 2 weeks without consulting a doctor. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients with renal impairment should use with caution due to risk of aluminium accumulation.

🤰 Pregnancy Planning (TTC)

Consult your doctor before use if you are planning pregnancy.

🏥 Post-Surgery Considerations

Consult your doctor before use after surgery, especially if you have difficulty swallowing.

🦷 Dental Procedures

Inform your dentist if you are using this medicine, as it may affect sensation in the mouth.

💚 Lifestyle Tips for Better Results

🏃
Avoid spicy and acidic foods that can irritate the stomach.
🥗
Eat smaller, more frequent meals.
😴
Avoid lying down immediately after eating.
💧
Maintain a healthy weight.
🧘
Quit smoking and limit alcohol.

🏋️ Exercise Considerations

No specific exercise restrictions, but avoid strenuous activity immediately after meals if you have GERD.

🥗 Diet Recommendations

Include fibre-rich foods to prevent constipation.
Stay well hydrated.
Avoid caffeine and carbonated drinks.

💼 Impact on Daily Work & Life

This medicine may cause mild numbness in the mouth, which could affect speech or swallowing temporarily. Avoid driving or operating machinery if you feel drowsy or numb.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if symptoms persist beyond 2 weeks or if you experience any serious side effects.

📅 Long-Term Use Effects

Long-term use of aluminium hydroxide may lead to constipation or, rarely, electrolyte imbalances. Prolonged use without medical supervision is not recommended. Regular monitoring may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet changes, weight loss, and avoiding trigger foods can help manage GERD.

Evidence: Well-established
Other antacids

Magnesium hydroxide or calcium carbonate may be alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If crossing time zones, continue your regular dosing schedule as closely as possible. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with recurrent mouth ulcers
She was prescribed this medicine for painful mouth ulcers. She applied it as directed and experienced significant pain relief within minutes. She noted that avoiding food for 30 minutes after use helped the medicine work better.
💡 Lesson: Proper application and timing enhance the effectiveness of this medicine.
👤 A 50-year-old man with GERD
He used this medicine after meals and at bedtime. His heartburn symptoms decreased noticeably within a few days. He also made lifestyle changes like avoiding spicy foods and late dinners.
💡 Lesson: Combining medicine with lifestyle modifications improves outcomes for GERD.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The local anaesthetic effect starts within minutes, while the antacid effect begins immediately.

Q: Can I use it for a sore throat?

A: Yes, it can help soothe a sore throat by numbing the area and reducing acid irritation.

Q: Is it safe for children?

A: Consult a pediatrician; dosing is not established for children.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for acecaine oral gel

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any stomach pain.
    Fact: It is specifically for acid-related discomfort and local pain; other causes of stomach pain require different treatment.
  • Myth: It is safe to use indefinitely.
    Fact: Prolonged use without medical supervision can lead to side effects like constipation or electrolyte imbalance.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Oxetacaine + Aluminium Hydroxide","uses":"Mouth ulcers, sore throat, GERD","notes":"Combined anaesthetic and antacid"},{"medicine":"Aluminium Hydroxide + Magnesium Hydroxide","composition":"Aluminium Hydroxide + Magnesium Hydroxide","uses":"Acid reflux, indigestion","notes":"Antacid only, no anaesthetic"}]

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