Falcigo 60mg Injection (Artesunate): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or chest pain after the injection
- Swelling of the face, lips, or throat
- Dark urine or much reduced urine output
- Yellowing of the eyes or skin
- Severe tiredness or unusual paleness after treatment
- Fast or irregular heartbeat
- Confusion, seizures, or loss of consciousness
- Fever that returns after finishing treatment
If experiencing severe symptoms, call emergency services immediately.
What is Tesam Injection Combipack used for?
This medicine is an injectable antimalarial used to treat severe malaria. It is given by a healthcare professional and works quickly to kill malaria parasites in the blood. It is followed by oral antimalarial therapy when the patient can take medicines by mouth.
- Generic Name: Artesunate (60mg)
- Manufacturer: Varenyam Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Tesam Injection Combipack के बारे में (Hindi Summary)
उपयोग: यह दवा गंभीर मलेरिया के इलाज के लिए दी जाती है। यह आर्टेसुनेट नाम की दवा का इंजेक्शन रूप है, जो मलेरिया परजीवी को खून में तेजी से मारता है। यह उन मरीजों के लिए उपयोग की जाती है जो मुंह से दवा नहीं ले सकते, जैसे बहुत कमजोर, बेहोश, या लगातार उल्टी करने वाले मरीज। यह दवा अस्पताल में डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दी जाती है। गंभीर मलेरिया में यह जान बचाने वाली दवा मानी जाती है। इसे घर पर खुद से नहीं लगाना चाहिए। इलाज के बाद डॉक्टर मुंह से ली जाने वाली मलेरिया की दवा भी दे सकते हैं ताकि बीमारी पूरी तरह ठीक हो जाए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, उल्टी, सिरदर्द, चक्कर आना और इंजेक्शन लगाने की जगह पर दर्द या लालिमा शामिल हैं। कुछ मरीजों को भूख कम लग सकती है या कमजोरी महसूस हो सकती है। गंभीर दुष्प्रभाव कम होते हैं, लेकिन इलाज के कुछ दिनों बाद खून की कमी यानी एनीमिया हो सकता है। इसलिए इलाज के बाद खून की जांच कराना जरूरी है। अगर बहुत ज्यादा थकान, पेशाब का रंग गहरा, आंखों का पीलापन, सांस लेने में तकलीफ, या दिल की धड़कन तेज हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: यह दवा सिर्फ अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा ही लगाई जानी चाहिए। इसे घर पर खुद से न लगाएं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर दिल की धड़कन को प्रभावित करने वाली दवाएं और खून पतला करने वाली दवाएं। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को जरूर बताएं। इलाज के दौरान शराब न पिएं। डॉक्टर द्वारा बताई गई खून की जांचें और फॉलो-अप जरूर कराएं। अगर इलाज के बाद बुखार फिर आए, पेशाब गहरा हो, या आंखें पीली दिखें, तो तुरंत डॉक्टर से संपर्क करें।
💊 Tesam Injection Combipack Uses & Benefits
[{"condition":"Severe malaria","description":"This medicine is used as first-line treatment for severe malaria caused by Plasmodium falciparum, including cerebral malaria and cases with organ dysfunction.","evidence":"Well-established"},{"condition":"Malaria in patients who cannot take oral medicines","description":"It is used when vomiting, unconsciousness, or severe illness prevents reliable oral intake of antimalarial tablets.","evidence":"Well-established"},{"condition":"Severe malaria in pregnancy","description":"It is used in pregnant women with severe malaria, especially in the second and third trimesters, because the benefits of treating severe malaria outweigh the risks.","evidence":"Well-established"},{"condition":"Severe malaria in children","description":"It is used in children with severe malaria, with dosing based on body weight and clinical status.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Severe malaria in the first trimester of pregnancy","description":"Use in the first trimester is sometimes considered when no better options are available, but this decision must be made by a specialist.","evidence":"Limited"},{"condition":"Combination with other antimalarials for severe disease","description":"In some settings, this medicine may be followed by a full course of oral combination antimalarial therapy to prevent recurrence.","evidence":"Well-established"}]
Primary treatment for: Severe malaria
Also treats: Cerebral malaria, Malaria with severe anaemia, Malaria with organ dysfunction, Malaria in patients who cannot take oral medicines
📋 Drug Information
| Generic Name(s) | Artesunate (60mg) |
| Brand Name | Tesam Injection Combipack |
| Manufacturer | Varenyam Healthcare Pvt Ltd |
| Packaging / Form | box of 1 Injection (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Parenteral |
| Storage | Store this medicine as directed on the label, usually at room temperature between 15°C and 30°C. Protect it from light and moisture. Do not freeze unless the manufacturer's instructions say it is safe. Keep it out of reach of children. |
| Shelf Life | The shelf life is usually 24 to 36 months from the date of manufacture, but the exact expiry date is printed on the pack. Do not use after the expiry date. |
| WHO Guideline | The World Health Organization recommends artesunate as the preferred treatment for severe malaria in adults, children, and pregnant women, with follow-up oral combination therapy when the patient can take medicines by mouth. This medicine is an artesunate injection and should be used within a supervised treatment protocol. |
| ICMR Guideline | Indian guidelines recommend parenteral artesunate for severe malaria, followed by a full course of oral artemisinin-based combination therapy once the patient can take oral medicines. Treatment should follow national malaria control programme recommendations. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through a multi-step process inside the malaria parasite. After entering the parasite, artesunate is converted to its active metabolite, dihydroartemisinin. This active form reacts with iron-containing molecules, especially haem released during the digestion of haemoglobin by the parasite. This reaction produces highly reactive oxygen species that damage parasite proteins, membranes, and essential enzymes. The parasite's ability to digest haemoglobin and maintain its internal balance is disrupted, leading to rapid parasite death. This medicine is most active against the blood-stage forms of the malaria parasite, which are responsible for the symptoms and complications of malaria.
Mechanism Steps
💡 How to Take Tesam Injection Combipack
Strength: This medicine is supplied as a 60 mg strength injection for parenteral use.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is based on body weight and is given by a healthcare professional. A common regimen is 2.4 mg per kg given by intravenous or intramuscular injection at 0, 12, and 24 hours, and then once daily if needed. The exact dose and duration depend on the severity of malaria, the patient's weight, kidney and liver function, and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. In practice, children with severe malaria may receive weight-based doses under specialist supervision, but the exact regimen must be determined by a qualified clinician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine and to complications of severe malaria. The dose is usually based on body weight and kidney and liver function. A clinician should individualize the dose and monitor closely for side effects. |
| Renal Impairment | Dose adjustment may be needed in patients with severe kidney impairment. The exact adjustment is not established from the available information. A qualified clinician should review kidney function and decide on the appropriate dose. |
| Hepatic Impairment | Dose adjustment may be needed in patients with severe liver impairment. The exact adjustment is not established from the available information. A qualified clinician should review liver function and decide on the appropriate dose. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Dosing must be determined by a qualified clinician based on the patient's condition and weight. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Tesam Injection Combipack
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other antimalarials | Major | |
| QT-prolonging medicines | Major | |
| Warfarin | Major | |
| Liver enzyme affecting medicines | Moderate | |
| Anaemia-causing medicines | Moderate | |
| Paracetamol | Minor | |
| Antacids | Minor | |
| Herbal supplements | Moderate | |
| Alcohol | Moderate | |
| Blood count affecting medicines | Moderate |
🚨 Major Interactions
- Other antimalarial medicines
- Medicines that prolong the QT interval
- Warfarin and other blood thinners
⚡ Moderate Interactions
- Medicines that affect liver enzymes
- Medicines that can cause anaemia
🍷 Alcohol Interaction
Alcohol should be avoided during treatment with this medicine. Severe malaria can cause dehydration and liver strain, and alcohol may make these problems worse. Alcohol can also increase the risk of dizziness and low blood sugar. If you drink alcohol regularly, tell your doctor so that they can give you appropriate advice.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to artesunate or related artemisinin medicines","Previous severe allergic reaction to this medicine","Use without proper medical supervision"]
⚠️ Warnings & Precautions
["This medicine must be given only by a qualified healthcare professional.","Delayed anaemia can occur days to weeks after treatment, so follow-up blood tests are important.","Use with caution in patients with liver or kidney disease.","Use with caution in patients taking other medicines that affect heart rhythm.","Tell your doctor if you are pregnant or breastfeeding.","Avoid alcohol during treatment.","Do not use this medicine for mild malaria that can be treated with oral medicines.","Report any unusual tiredness, dark urine, or yellow eyes promptly."]
🤱 Lactation Safety
This medicine is generally considered acceptable during breastfeeding when needed for severe malaria. Small amounts may pass into breast milk, but the benefits of treating severe malaria usually outweigh the risks. Mothers should discuss breastfeeding with their doctor during treatment.
💊 Overdose Management
Overdose with this medicine is unlikely because it is given by a healthcare professional. If too much is given, treatment should focus on supportive care, monitoring of blood counts, liver and kidney function, and heart rhythm. There is no specific antidote. Contact a poison control centre or emergency department if an overdose is suspected.
⏰ Missed Dose
Because this medicine is given by a healthcare professional, missed doses are managed by the treating team. If you miss a scheduled injection, contact your doctor or hospital as soon as possible. Do not try to catch up by taking extra doses on your own. The treatment schedule should be completed as prescribed to fully clear the malaria parasite.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional in a setting where severe malaria can be properly managed. Do not attempt to self-administer this injection. Inform your doctor about all medicines you are taking, especially other antimalarials, medicines that affect heart rhythm, and blood thinners. Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. Blood tests may be needed before, during, and after treatment to check parasite levels, blood counts, liver function, and kidney function. Avoid alcohol during treatment because it may worsen dehydration and liver stress. Keep all follow-up appointments, because delayed anaemia can occur after the injection course is finished. If you notice dark urine, yellow eyes, unusual tiredness, or fever returning after treatment, seek medical care promptly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may have a higher risk of complications from severe malaria and may be more sensitive to side effects. Kidney and liver function should be checked, and the dose should be individualized. Close monitoring for anaemia, heart rhythm changes, and dehydration is important.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss malaria prevention with your doctor, especially if you travel to malaria-endemic areas. This medicine is used for severe malaria during pregnancy when needed. It is not a medicine for routine use before or during pregnancy without a clear diagnosis of severe malaria.
🏥 Post-Surgery Considerations
If you have recently had surgery and develop severe malaria, this medicine can be used under specialist care. Tell your surgical team and your malaria doctor about all medicines you are taking, including blood thinners, because the risk of bleeding may be higher.
🦷 Dental Procedures
Tell your dentist if you are being treated with this medicine or have recently completed treatment. Dental procedures are usually safe, but your dentist may want to know about your recent illness and any blood count changes. If you had delayed anaemia, your dentist may advise waiting until your blood counts improve.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until you have fully recovered from severe malaria. Start with light activity and increase gradually as your strength returns. Ask your doctor before returning to intense exercise, especially if you had anaemia or heart rhythm changes.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Severe malaria and its treatment can keep you in hospital for several days. You may feel weak and tired for some time after discharge. Avoid driving or operating heavy machinery until you feel fully alert and your doctor says it is safe. Plan for rest and follow-up appointments before returning to your normal routine.
🛑 When to Stop This Medicine
Do not stop treatment on your own. This medicine is given by a healthcare professional, and the course is decided by your doctor. If you develop serious side effects, your doctor may change the treatment. Always complete the full course and follow-up oral therapy as prescribed.
📅 Long-Term Use Effects
Most people recover fully after treatment with this medicine. The main long-term concern is delayed anaemia, which can occur days to weeks after treatment, so follow-up blood tests are important. Rarely, liver or blood count changes may need monitoring. There are no known long-term effects on fertility or organ function when the medicine is used as prescribed. If you notice persistent tiredness, yellow eyes, or dark urine after treatment, seek medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another artemisinin derivative that can be used for severe malaria when artesunate is not available.
Evidence: Well-establishedAn older injectable antimalarial that may be used when artemisinin derivatives are not available.
Evidence: Well-establishedA temporary option for pre-referral treatment when injection is not possible.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no specific interaction between this medicine and routine vaccines. If you are due for a vaccine, tell your doctor about your malaria treatment. In general, vaccines can be given when you are medically stable, but the timing should be decided by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not freeze unless the manufacturer's instructions say it is safe
✅ DO
Keep in the original container with the label intact
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from direct sunlight and moisture
❌ DON'T
Do not store in a bathroom cabinet
✅ DO
Check the expiry date before use
❌ DON'T
Do not use if the solution is discoloured or contains particles
✈️ Traveling with This Medicine
If you are travelling and need this medicine, carry it in its original packaging with the prescription and a letter from your doctor. Keep it in a cool, dry place and protect it from direct sunlight. Check the expiry date before travel. If you are travelling to a malaria-endemic area, follow malaria prevention advice, including mosquito bite prevention and preventive medicines if prescribed. If you develop fever during or after travel, seek medical care immediately and tell the doctor where you travelled.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts reducing malaria parasites in the blood within hours, but full recovery takes longer and depends on the severity of the infection.
A: No. This medicine must be given by a qualified healthcare professional in a hospital or clinic setting.
A: Yes. Most patients need a full course of oral antimalarial tablets after the injections to prevent the infection from returning.
A: Your doctor may check blood counts, liver function, kidney function, and parasite levels during and after treatment.
A: It is used in pregnancy when severe malaria is present, especially in the second and third trimesters, under specialist care.
🤔 Common Patient Concerns
🔄 Substitutes for Tesam Injection Combipack
View AllAlternative brands with exact same active ingredient:
-
oxynate-ar 60mg injectionOxytech ₹16.69 60.4% CHEAPER
-
artijen 60mg injectionJenfer Biosciences Pvt Ltd ₹30.00 28.9% CHEAPER
-
arteross 60mg injectionWockhardt Ltd ₹36.33 13.9% CHEAPER
-
falciart 60mg injectionIntas Pharmaceuticals Ltd ₹52.73 25% COSTLIER
-
barinate 60mg tabletAbaris Healthcare ₹59.98 42.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any fever.
Fact: This medicine is specifically for severe malaria and should not be used for other causes of fever without confirmation. - Myth: This medicine can be self-injected at home.
Fact: This medicine must be given by a qualified healthcare professional in a supervised setting. - Myth: Once you feel better, you can stop treatment.
Fact: The full course and follow-up oral therapy are needed to prevent relapse and complications. - Myth: This medicine is safe for everyone.
Fact: It should be avoided in people with a known allergy to artesunate or related medicines.
🔄 Alternative Options
Generic Alternatives
- Artesunate injection
Brand Alternatives
- Falcigo 60mg injection