Terbis-A Syrup - Terbutaline (1.25mg/5ml) + Acebrophylline (50mg/5ml) medicine

e-tag Syrup: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Albris Healthcare And Biotech Pvt Ltd 📦 bottle of 100 ml Syrup 💊 Allopathy 📅 Updated: Oct 16, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for bronchodilation in asthma and COPD.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing)
  • Chest pain or irregular heartbeat
  • Severe headache with visual changes
  • Muscle weakness or cramps (possible low potassium)
  • Seizures
  • Yellowing of skin or eyes (jaundice)
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is Terbis-A Syrup used for?

This medicine is a combination of terbutaline and acebrophylline used to treat bronchospasm in asthma and COPD. It works by relaxing airway muscles and reducing inflammation. It is available as a syrup and is taken orally, usually 5-10 ml two to three times daily, as prescribed by a doctor.

  • Generic Name: Terbutaline (1.25mg/5ml) + Acebrophylline (50mg/5ml)
  • Manufacturer: Albris Healthcare And Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Terbis-A Syrup के बारे में (Hindi Summary)

उपयोग: यह दवा टर्ब्यूटलीन और एसीब्रोफिलीन का संयोजन है, जिसका उपयोग अस्थमा और सीओपीडी जैसी स्थितियों में श्वसन मार्ग की मांसपेशियों को आराम देकर सांस लेने में आसानी प्रदान करने के लिए किया जाता है। यह ब्रोंकोस्पाज्म को कम करती है और सूजन को कम करने में मदद करती है। यह केवल डॉक्टर के परामर्श से ही लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मतली, उल्टी, पेट की गड़बड़ी, बेचैनी, हाथ-पैर कांपना, धड़कन तेज होना और घबराहट शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें एलर्जी, छाती में दर्द, अनियमित दिल की धड़कन और पोटैशियम की कमी हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। यह दवा नींद या चक्कर ला सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। शराब का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें। बच्चों को डॉक्टर की सलाह के बिना न दें। दवा को बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 Terbis-A Syrup Uses & Benefits

  • [{"condition":"Asthma","description":"This medicine helps to relieve bronchospasm and improve breathing in patients with asthma.
  • It is used as a bronchodilator and may be prescribed for both acute attacks and long-term management.","evidence":"Well-established"},{"condition":"Chronic Obstructive Pulmonary Disease (COPD)","description":"This medicine helps to relax the airways and reduce breathlessness in patients with COPD.
  • It may be used as part of a comprehensive treatment plan.","evidence":"Well-established"},{"condition":"Bronchitis","description":"This medicine may be used to relieve wheezing and shortness of breath associated with bronchitis, especially when there is a bronchospastic component.","evidence":"Moderate"},{"condition":"Bronchial asthma with reversible airway obstruction","description":"This medicine is indicated for the relief of bronchospasm in patients with reversible obstructive airway disease.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Premature labor (tocolysis)","description":"Terbutaline, one of the components, has been used off-label to delay premature labor, but this use is not recommended due to safety concerns for the mother and fetus.","evidence":"Limited and controversial"}]

Primary treatment for: Asthma

Also treats: Chronic Obstructive Pulmonary Disease (COPD), Bronchitis, Bronchospasm

📋 Drug Information

Generic Name(s)Terbutaline (1.25mg/5ml) + Acebrophylline (50mg/5ml)
Brand NameTerbis-A Syrup
ManufacturerAlbris Healthcare And Biotech Pvt Ltd
Packaging / Formbottle of 100 ml Syrup (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not refrigerate. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always shake the bottle well before measuring the dose.
2
Use a proper measuring cup or spoon to ensure accurate dosing.
3
Take this medicine with food if it causes stomach upset.
4
Do not exceed the prescribed dose, as it can cause serious heart and nervous system effects.
5
Inform your doctor if you have heart disease, high blood pressure, or diabetes before taking this medicine.
6
Avoid driving or operating machinery until you know how this medicine affects you.
7
Do not stop taking this medicine abruptly without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Wheezing
This medicine is commonly prescribed for wheezing due to bronchospasm.
Likely Use
✅
Shortness of breath
This medicine helps relieve shortness of breath in asthma and COPD.
Likely Use
✅
Chest tightness
This medicine can help relax airway muscles and reduce chest tightness.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Productive cough
This medicine is not primarily used for cough with mucus; other medicines may be needed.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTerbutaline is rapidly absorbed from the gastrointestinal tract after oral administration. Acebrophylline is also absorbed orally. However, oral bioavailability of terbutaline is reduced due to first-pass metabolism. Specific pharmacokinetic parameters for the combination syrup are not established from the available information.
DistributionTerbutaline distributes widely into body tissues, including the lungs. It crosses the placenta and is excreted in breast milk. Acebrophylline distribution is not well characterized. Protein binding information for the combination is not established from the available information.
Protein BindingTerbutaline is approximately 25% bound to plasma proteins. Acebrophylline protein binding is not established from the available information.
MetabolismTerbutaline undergoes extensive first-pass metabolism in the liver, primarily by conjugation to sulfate and glucuronide metabolites. Acebrophylline is metabolized in the liver, but specific pathways are not well defined.
Half-LifeThe elimination half-life of terbutaline is approximately 3 to 4 hours. The half-life of acebrophylline is not established from the available information.
ExcretionTerbutaline and its metabolites are excreted primarily in the urine. Acebrophylline excretion is not well characterized.
BioavailabilityOral bioavailability of terbutaline is approximately 10-15% due to first-pass metabolism. Bioavailability of acebrophylline from the combination is not established from the available information.
Onset of ActionBronchodilation from terbutaline typically occurs within 30 minutes after oral administration. Onset for acebrophylline may be slower.
Peak Plasma TimePeak plasma concentration of terbutaline is reached in about 2-3 hours after oral administration. Peak for acebrophylline is not established from the available information.
Duration of ActionThe bronchodilator effect of terbutaline lasts about 4-6 hours. Duration for acebrophylline is not established from the available information.

How It Works

This medicine contains two active ingredients with complementary mechanisms. Terbutaline is a selective beta-2 adrenergic receptor agonist that binds to beta-2 receptors on bronchial smooth muscle, leading to relaxation and bronchodilation. Acebrophylline is a xanthine derivative that inhibits phosphodiesterase enzymes, increasing cyclic AMP levels, which also leads to bronchial smooth muscle relaxation. Additionally, acebrophylline has anti-inflammatory effects and may improve mucociliary clearance. Together, they provide bronchodilation and help relieve bronchospasm.

Mechanism Steps

1
Terbutaline binds to beta-2 receptors: Terbutaline selectively binds to beta-2 adrenergic receptors on the surface of bronchial smooth muscle cells.
2
Activation of intracellular signaling: Binding triggers activation of adenylate cyclase, which increases cyclic AMP levels inside the cell.
3
Bronchial smooth muscle relaxation: Elevated cyclic AMP leads to relaxation of the smooth muscle, resulting in bronchodilation and easier breathing.
4
Acebrophylline inhibits phosphodiesterase: Acebrophylline inhibits phosphodiesterase enzymes, preventing the breakdown of cyclic AMP, thus prolonging its effects.
5
Anti-inflammatory action: Acebrophylline also reduces the release of inflammatory mediators from mast cells and other immune cells, decreasing airway inflammation.

💡 How to Take Terbis-A Syrup

Strength: Each 5 ml of syrup contains Terbutaline 1.25 mg and Acebrophylline 50 mg.

1Shake the bottle well before each use.
2Use a measuring cup or spoon to measure the prescribed dose accurately.
3Take the medicine orally, with or without food.
4If it causes stomach upset, take it with a meal or snack.
5Do not exceed the recommended dose.
6Follow your doctor's instructions regarding the duration of treatment.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5-10 ml (1-2 teaspoons) taken orally two to three times a day, or as directed by your physician. The dose may be adjusted based on your condition and response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Use with caution and start with a lower dose. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum daily dose should not exceed 30 ml (6 teaspoons) in adults, or as prescribed by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase nervousness and tremor.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Terbis-A Syrup

✅ Common Side Effects

Tremor (Common (5-10%))
Usually diminishes with continued use. If severe, consult your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if persistent.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if severe.
Palpitations (Common (5-10%))
Report to your doctor if you experience fast or irregular heartbeat.
Nervousness (Common (5-10%))
Usually temporary. Consult doctor if it interferes with daily activities.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, tongue, or throat, or difficulty breathing.
Cardiac arrhythmias (Rare (<0.1%))
Seek immediate medical attention if you experience chest pain, palpitations, or fainting.
Hypokalemia (low potassium) (Rare (<0.1%))
Report muscle weakness, cramps, or fatigue to your doctor.
Seizures (Rare (<0.1%))
Seek immediate medical attention if seizures occur.

⚠️ Rare Side Effects

Hyperglycemia
Monitor blood sugar if diabetic. Consult doctor if levels are high.
Hypotension
Report dizziness or fainting to your doctor.
Restlessness
Usually temporary. Consult doctor if persistent.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Furosemide Moderate
Corticosteroids Moderate
Digoxin Moderate
Antacids Minor
Caffeine Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and cardiovascular side effects. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to terbutaline, acebrophylline, or any component of the formulation","Severe cardiovascular disease (e.g., severe coronary insufficiency, cardiac arrhythmias)","Uncontrolled hypertension","Hyperthyroidism","Diabetes mellitus (relative)","Seizure disorders (relative)"]

⚠️ Warnings & Precautions

["This medicine should be used with caution in patients with cardiovascular disorders, including coronary insufficiency, arrhythmias, and hypertension.","It may cause hypokalemia; monitor potassium levels, especially in patients taking diuretics or corticosteroids.","It may cause hyperglycemia; monitor blood glucose in diabetic patients.","It may cause tremor and nervousness; caution when driving or operating machinery.","Do not exceed the recommended dose; overdose can cause severe cardiac and neurological effects.","Use with caution in elderly patients and those with renal or hepatic impairment.","Safety and effectiveness in children have not been established for all indications."]

🤱 Lactation Safety

Terbutaline is excreted in breast milk. It is not known whether acebrophylline is excreted in breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe tachycardia, palpitations, tremor, nausea, vomiting, hypokalemia, hyperglycemia, and cardiac arrest. Treatment is supportive and symptomatic. There is no specific antidote. If overdose is suspected, seek immediate medical attention. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs, electrolytes, and cardiac rhythm.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or a history of seizures. This medicine may cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you. Do not take this medicine with other stimulants or decongestants without consulting your doctor, as it may increase the risk of side effects. Avoid alcohol while taking this medicine, as it can worsen dizziness and drowsiness. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms. Keep out of reach of children. Store at room temperature away from moisture and heat. Do not use after the expiry date.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular and neurological effects of this medicine. Use with caution, starting at a lower dose. Monitor heart rate, blood pressure, and electrolytes regularly.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Terbutaline is Pregnancy Category C and should be used only if clearly needed. Discuss alternative treatments if appropriate.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with anesthetic agents and affect heart rate and blood pressure. Your doctor may advise temporary discontinuation.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may cause dry mouth or interact with local anesthetics containing epinephrine. Your dentist may take precautions.

💚 Lifestyle Tips for Better Results

🏃
Avoid triggers such as smoke, dust, and cold air.
🥗
Practice breathing exercises to improve lung function.
😴
Maintain a healthy weight to reduce strain on your lungs.
💧
Stay hydrated to keep airways moist.
🧘
Get adequate rest and sleep.
🌞
Follow a balanced diet rich in fruits and vegetables.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have breathing difficulties. Consult your doctor before starting any exercise program. Gentle activities like walking or swimming may be beneficial.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce intake of processed and fried foods.
Stay well hydrated.
Limit caffeine intake as it may increase side effects.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, drowsiness, or tremor, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause restlessness, which can impact concentration.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your condition worsens, contact your doctor immediately. Your doctor will advise you on whether to continue, adjust, or stop the medicine.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, reduced effectiveness, and increased risk of side effects such as tremors, palpitations, and hypokalemia. Regular monitoring of heart rate, blood pressure, and electrolyte levels is recommended. Do not use for prolonged periods without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled bronchodilators

Inhaled medicines like salbutamol may be used as alternatives or in addition to oral therapy.

Evidence: Well-established
Inhaled corticosteroids

For long-term control of asthma, inhaled corticosteroids are often prescribed.

Evidence: Well-established
Leukotriene receptor antagonists

Oral medicines like montelukast may be used for asthma prophylaxis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you have asthma or COPD, you may be advised to get influenza and pneumococcal vaccines. Consult your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Always carry enough supply for your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with asthma
She was prescribed this medicine for her asthma symptoms. She noticed significant improvement in her breathing within a few days. She experienced mild hand tremors initially, which decreased over time. She advises taking it with food to avoid stomach upset.
💡 Lesson: Consistent use as prescribed and taking with food can improve tolerability and effectiveness.
👤 A 60-year-old man with COPD
He started this medicine as part of his COPD management. His wheezing and shortness of breath improved, allowing him to walk longer distances. He had to monitor his heart rate as he has mild hypertension. He emphasizes the importance of regular check-ups.
💡 Lesson: Regular monitoring and communication with your doctor are key when using this medicine, especially if you have other health conditions.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 minutes after oral administration, with peak effects in about 2-3 hours.

Q: Can I take this medicine if I have diabetes?

A: This medicine may increase blood sugar levels. If you have diabetes, monitor your blood glucose closely and inform your doctor.

Q: Is it safe to take this medicine during pregnancy?

A: Terbutaline is Pregnancy Category C. Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant.

Q: Can I take this medicine with other asthma medicines?

A: It depends on the specific medicines. Always inform your doctor about all medicines you are taking to avoid interactions.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Terbis-A Syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure asthma permanently.
    Fact: This medicine helps manage symptoms but does not cure asthma. Asthma requires long-term management.
  • Myth: It is safe to take extra doses if breathing difficulty worsens.
    Fact: Taking extra doses can cause serious heart and nervous system side effects. Always follow your doctor's prescription.
  • Myth: This medicine is safe for children without doctor's supervision.
    Fact: Pediatric dosing is not established. Consult a pediatrician before giving this medicine to a child.

🔄 Alternative Options

Generic Alternatives

  • Terbutaline + Acebrophylline syrup (various manufacturers)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Terbutaline 1.25mg/5ml + Acebrophylline 50mg/5ml","route":"Oral","primary_use":"Bronchospasm in asthma/COPD"},{"medicine":"Terbutaline + Bromhexine syrup","composition":"Terbutaline + Bromhexine","route":"Oral","primary_use":"Bronchospasm with mucus"},{"medicine":"Acebrophylline syrup","composition":"Acebrophylline","route":"Oral","primary_use":"Bronchospasm and inflammation"}]

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