Met XL 3D 50/6.25 Tablet: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Very slow heart rate (below 50 beats per minute)
- Difficulty breathing or wheezing
- Swelling of face, lips, tongue, or throat
- Chest pain or tightness
- Sudden weight gain or swelling in legs
- Muscle cramps or weakness
- Irregular heartbeat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is telma-mct 50/6.25 tablet er used for?
This medicine is a combination of chlorthalidone and metoprolol succinate used to treat high blood pressure. It works by reducing fluid volume and slowing the heart rate. Take it once daily in the morning as prescribed.
- Generic Name: Chlorthalidone (6.25mg) + Metoprolol Succinate (50mg)
- Manufacturer: Glenmark Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 telma-mct 50/6.25 tablet er के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। इसमें क्लोर्थालिडोन और मेटोप्रोलोल सक्सिनेट दो सक्रिय तत्व हैं। क्लोर्थालिडोन शरीर से अतिरिक्त नमक और पानी को बाहर निकालने में मदद करता है, जिससे रक्तचाप कम होता है। मेटोप्रोलोल सक्सिनेट हृदय की गति को धीमा करता है और हृदय पर दबाव कम करता है। यह दवा उन रोगियों के लिए है जिनका रक्तचाप एक दवा से नियंत्रित नहीं हो रहा है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द, और हृदय गति का धीमा होना शामिल है। कुछ रोगियों को पेशाब बार-बार आ सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, बेहोशी, या दिल की धड़कन बहुत धीमी लगे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें। दवा लेने के बाद चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब न पिएं। पर्याप्त पानी पिएं। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं। अपने डॉक्टर को अन्य दवाओं के बारे में बताएं।
💊 telma-mct 50/6.25 tablet er Uses & Benefits
[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"},{"condition":"Heart failure with reduced ejection fraction","description":"Metoprolol succinate component is used to improve survival and reduce hospitalizations in stable heart failure patients.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"The metoprolol component helps reduce the frequency and severity of angina attacks by decreasing heart workload.","evidence":"Well-established"},{"condition":"Edema due to heart failure, liver cirrhosis, or kidney disease","description":"The chlorthalidone component helps remove excess fluid, but this combination is not first-line for edema alone.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Beta-blockers like metoprolol are sometimes used off-label to prevent migraines, but this combination is not standard for that purpose.","evidence":"Limited"},{"condition":"Performance anxiety","description":"Beta-blockers may be used off-label to reduce symptoms of anxiety, but this combination is not typically recommended.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Heart failure, Angina pectoris, Post-myocardial infarction
📋 Drug Information
| Generic Name(s) | Chlorthalidone (6.25mg) + Metoprolol Succinate (50mg) |
| Brand Name | telma-mct 50/6.25 tablet er |
| Manufacturer | Glenmark Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Chlorthalidone inhibits the sodium-chloride symporter in the distal convoluted tubule of the kidney, increasing the excretion of sodium, chloride, and water. This reduces plasma volume and, over time, lowers peripheral vascular resistance. Metoprolol succinate selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output. It also suppresses renin release from the kidneys, which reduces angiotensin II and aldosterone levels, contributing to blood pressure reduction. The combination provides a more effective blood pressure lowering than either agent alone.
Mechanism Steps
💡 How to Take telma-mct 50/6.25 tablet er
Strength: Tablet containing chlorthalidone 6.25 mg and metoprolol succinate 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and low blood pressure. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with kidney impairment, chlorthalidone may be less effective and can worsen kidney function. Metoprolol dose may need adjustment. Consult your doctor for dose adjustments based on creatinine clearance. |
| Hepatic Impairment | In patients with liver impairment, metoprolol metabolism may be reduced, leading to increased effects. Start with a lower dose and monitor carefully. Consult your doctor for dose adjustments. |
| Maximum Daily Dose | The maximum recommended daily dose of this combination is one tablet (chlorthalidone 6.25 mg + metoprolol succinate 50 mg) once daily. Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of telma-mct 50/6.25 tablet er
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Diltiazem | Major | |
| Digoxin | Major | |
| Fluoxetine | Major | |
| Lithium | Major | |
| NSAIDs | Major | |
| Propranolol | Major | |
| Prazosin | Moderate | |
| Amitriptyline | Moderate | |
| Insulin | Moderate |
🚨 Major Interactions
- Other beta-blockers (e.g., propranolol, atenolol)
- Calcium channel blockers (e.g., verapamil, diltiazem)
- Digoxin
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- Lithium
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
⚡ Moderate Interactions
- Alpha-blockers (e.g., prazosin, terazosin)
- Tricyclic antidepressants (e.g., amitriptyline)
- Corticosteroids
- Antidiabetic drugs (e.g., insulin, sulfonylureas)
- Carbamazepine
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can enhance the blood pressure-lowering and dizziness effects of both chlorthalidone and metoprolol, increasing the risk of fainting and falls. It can also worsen dehydration caused by the diuretic component.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to chlorthalidone, metoprolol, or other beta-blockers","Severe bradycardia (heart rate < 50 beats per minute)","Second or third-degree heart block without a pacemaker","Cardiogenic shock","Decompensated heart failure","Severe asthma or chronic obstructive pulmonary disease with bronchospasm","Severe peripheral arterial disease","Untreated pheochromocytoma","Anuria or severe kidney failure","Pregnancy (especially second and third trimesters)"]
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly, as it can cause rebound hypertension, angina, or heart attack. Taper gradually under medical supervision.","This medicine may mask symptoms of hypoglycemia in diabetic patients. Monitor blood glucose closely.","Use with caution in patients with liver disease, as metoprolol metabolism may be impaired.","Chlorthalidone can cause dehydration and electrolyte imbalance. Maintain adequate fluid intake and monitor electrolytes.","This medicine may worsen symptoms of Raynaud's phenomenon or peripheral vascular disease.","Avoid use in patients with a history of severe allergic reactions, as beta-blockers may reduce the effectiveness of epinephrine used to treat anaphylaxis.","This medicine can cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have a history of depression, as beta-blockers may worsen symptoms."]
🤱 Lactation Safety
Chlorthalidone and metoprolol are excreted in breast milk. Chlorthalidone may reduce milk production. Metoprolol is considered compatible with breastfeeding with monitoring for infant bradycardia. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose of this medicine can cause severe bradycardia, hypotension, heart failure, bronchospasm, and electrolyte disturbances. Seek immediate medical attention. Treatment is supportive and may include intravenous fluids, atropine for bradycardia, vasopressors for hypotension, and beta-agonists for bronchospasm. Hemodialysis may be considered for chlorthalidone removal but is not effective for metoprolol.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. This medicine can cause dizziness, so avoid driving or operating heavy machinery until you know how it affects you. Stand up slowly from a sitting or lying position to prevent dizziness. Drink enough water to stay hydrated, but follow your doctor's advice if you have fluid restrictions. Avoid alcohol, as it can increase dizziness and low blood pressure. Inform your doctor about all other medicines, supplements, and herbal products you are taking. Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor. Keep all follow-up appointments for blood pressure and blood test monitoring.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of this medicine, especially dizziness, low blood pressure, and electrolyte imbalances. Start with a lower dose and monitor closely. Regular monitoring of kidney function, electrolytes, and heart rate is important. Falls risk may be increased due to dizziness.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before conception. This medicine may not be safe during pregnancy, especially in the second and third trimesters. Your doctor may switch you to a safer alternative. Use effective contraception while taking this medicine unless otherwise advised.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate and blood pressure during surgery. Your doctor may advise you to continue or temporarily stop the medicine before surgery. Do not stop without medical advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or increase the risk of bleeding. Your dentist may need to take precautions, especially if you are also taking blood thinners. Continue taking your medicine as usual unless your doctor advises otherwise.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe and beneficial while taking this medicine. However, because it can cause dizziness and low blood pressure, avoid sudden strenuous activities or heavy lifting until you know how the medicine affects you. Stay hydrated during exercise. If you feel dizzy, weak, or short of breath, stop and rest. Consult your doctor before starting a new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, tiredness, or slow heart rate, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause increased urination, so plan bathroom breaks. Most people can continue their normal work and daily activities with proper monitoring and dose adjustment.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Abrupt discontinuation can cause rebound hypertension, angina, or heart attack. Your doctor may gradually reduce the dose if needed. If you experience severe side effects, contact your doctor immediately for advice on alternative treatment.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of blood pressure, heart rate, kidney function, and electrolyte levels. Chlorthalidone can cause electrolyte imbalances and increased blood sugar or uric acid levels. Metoprolol may cause fatigue, cold extremities, and sexual dysfunction. Do not stop the medicine abruptly. Regular follow-up with your doctor is essential to adjust the dose and monitor for complications.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, weight loss, and stress reduction can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, angiotensin receptor blockers, calcium channel blockers, or other diuretics may be used as alternatives based on individual needs.
Evidence: Well-establishedA procedure that may be considered for resistant hypertension in selected patients.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for any vaccination, inform your healthcare provider about all medicines you are taking. Continue taking this medicine as prescribed unless your doctor advises otherwise.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, continue taking your dose at the same local time each day. Consult your doctor if you need to adjust timing. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but the full effect may take 2 to 4 weeks. Continue taking it regularly as prescribed.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.
A: If you remember within 12 hours, take the missed dose. If more than 12 hours have passed, skip it and continue with your regular schedule. Do not double dose.
A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause dangerous rebound hypertension.
A: Consult your doctor. This medicine may not be safe during pregnancy, especially in the second and third trimesters. Alternative treatments may be recommended.
🤔 Common Patient Concerns
🔄 Substitutes for telma-mct 50/6.25 tablet er
View AllAlternative brands with exact same active ingredient:
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acmprol c 50mg/6.25mg tablet erAccilex Diacardo ₹59.00 56.6% CHEAPER
-
clovet m 50mg/6.25mg tabletAjanta Pharma Ltd ₹62.26 54.2% CHEAPER
-
Topme-C 50mg/6.25mg TabletJohnlee Pharmaceuticals Pvt Ltd ₹75.00 44.8% CHEAPER
-
bitatel m 3d 6.25mg/50mg/40mg tablet4Care Lifescience Pvt Ltd ₹112.50 17.2% CHEAPER
-
starpress 3d 6.25mg/50mg/40mg tabletLupin Ltd ₹121.07 10.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause dangerous rebound hypertension. - Myth: This medicine causes kidney damage in everyone.
Fact: While chlorthalidone can affect kidney function, regular monitoring helps prevent serious problems. Many patients take it safely for years. - Myth: You can eat anything while taking this medicine.
Fact: A low-sodium diet is important for blood pressure control. High-sodium foods can reduce the effectiveness of this medicine.
🔄 Alternative Options
Generic Alternatives
- Chlorthalidone + Metoprolol Succinate Tablet
Brand Alternatives
- Met XL 3D 50/6.25 Tablet