Chlorthalidone 6.25mg Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Irregular or rapid heartbeat
- Severe muscle weakness or cramps
- Confusion or seizures
- Severe abdominal pain with nausea and vomiting
- Blood in urine or stool
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Severe skin rash or blistering
If experiencing severe symptoms, call emergency services immediately.
What is tensiclor 6.25 tablet used for?
Chlorthalidone 6.25 mg is a low-dose thiazide-like diuretic used to treat high blood pressure. It works by helping the kidneys remove excess salt and water, which lowers blood pressure and reduces the risk of heart attack and stroke. It is usually taken once daily in the morning.
- Generic Name: Chlorthalidone (6.25mg)
- Manufacturer: Zeelab Pharmacy Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 tensiclor 6.25 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। यह शरीर से अतिरिक्त नमक और पानी को बाहर निकालने में मदद करती है, जिससे रक्तचाप कम होता है और दिल के दौरे तथा स्ट्रोक का खतरा घटता है। इसके अलावा, यह शरीर में पानी के जमाव (एडिमा) को कम करने में भी मदद करती है, जो हृदय विफलता या गुर्दे की बीमारी में हो सकता है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में बार-बार पेशाब आना, चक्कर आना, सिरदर्द, कमजोरी और मांसपेशियों में ऐंठन शामिल हैं। कभी-कभी यह शरीर में पोटैशियम और सोडियम की मात्रा को कम कर सकती है, जिससे थकान, मांसपेशियों में कमजोरी या दिल की धड़कन अनियमित हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको गंभीर पेट दर्द, त्वचा पर चकत्ते, या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। यह दवा चक्कर आ सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें जब तक आपको इसका असर पता न चल जाए। पर्याप्त पानी पिएं और शराब से बचें। अपने डॉक्टर द्वारा बताए गए नियमित रक्त परीक्षण करवाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को अचानक बंद न करें।
💊 tensiclor 6.25 tablet Uses & Benefits
[{"condition":"Hypertension","description":"Lowers blood pressure by promoting sodium and water excretion, reducing fluid volume and vascular resistance.","evidence":"Well-established"},{"condition":"Edema","description":"Helps relieve fluid retention in conditions such as heart failure, liver cirrhosis, and kidney disorders.","evidence":"Well-established"},{"condition":"Heart failure","description":"Used as an adjunct to reduce fluid overload and improve symptoms in chronic heart failure.","evidence":"Established"},{"condition":"Nephrogenic diabetes insipidus","description":"Paradoxically reduces urine output in this rare condition by decreasing glomerular filtration rate.","evidence":"Limited"},{"condition":"Calcium nephrolithiasis","description":"Reduces urinary calcium excretion, which may help prevent calcium kidney stones.","evidence":"Limited"}]
Off-label uses: [{"condition":"Osteoporosis","description":"Thiazide-like diuretics may reduce urinary calcium loss and help preserve bone mineral density.","evidence":"Limited"},{"condition":"Ménière's disease","description":"Sometimes used to reduce endolymphatic fluid pressure, but evidence is not strong.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Edema, Heart failure, Nephrogenic diabetes insipidus, Calcium nephrolithiasis
📋 Drug Information
| Generic Name(s) | Chlorthalidone (6.25mg) |
| Brand Name | tensiclor 6.25 tablet |
| Manufacturer | Zeelab Pharmacy Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Low-ceiling Diuretics (Inhibitors of Na+Cl symport) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends thiazide and thiazide-like diuretics, including chlorthalidone, as first-line treatment for hypertension in adults, either alone or in combination with other antihypertensive drugs. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) guidelines for hypertension recommend thiazide diuretics as one of the first-line options for the management of hypertension in India. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the sodium-chloride symporter in the distal convoluted tubule of the kidney. This action reduces the reabsorption of sodium and chloride, leading to increased excretion of water and electrolytes. The loss of sodium and water lowers blood volume and cardiac output initially, and with continued use, it reduces peripheral vascular resistance. This dual effect helps lower blood pressure. Additionally, the medicine reduces urinary calcium excretion, which can be beneficial in certain conditions. The exact mechanism for its antihypertensive effect also involves a direct vasodilatory action, although this is not fully understood.
Mechanism Steps
💡 How to Take tensiclor 6.25 tablet
Strength: Chlorthalidone 6.25 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for hypertension is 6.25 mg to 25 mg once daily. The dose may be increased based on your blood pressure response, up to a maximum of 100 mg per day, but doses above 25 mg are rarely used. For edema, the typical dose is 25 mg to 100 mg once daily or on alternate days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Take this medicine in the morning with or without food to avoid nighttime urination. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of chlorthalidone, especially dizziness and electrolyte imbalances. Start with a low dose (6.25 mg) and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is usually needed, but monitor renal function and electrolytes. In severe renal impairment (eGFR <30 mL/min/1.73 m²), chlorthalidone may be less effective and is generally not recommended. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Start with a low dose and monitor for signs of hepatic encephalopathy. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 100 mg, but doses above 25 mg are rarely used for hypertension. For edema, up to 200 mg per day may be used in some cases, but this is not common. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of tensiclor 6.25 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Lithium | Major | |
| Digoxin | Major | |
| NSAIDs | Moderate | |
| Corticosteroids | Moderate | |
| Warfarin | Moderate | |
| Metformin | Moderate | |
| Cholestyramine | Moderate | |
| Calcium supplements | Moderate | |
| Antacids | Minor | |
| Vitamin D | Minor |
🚨 Major Interactions
- Lithium
- Digoxin
- Corticosteroids
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Other antihypertensives
⚡ Moderate Interactions
- Metformin
- Warfarin
- Cholestyramine
- Calcium supplements
🍷 Alcohol Interaction
Alcohol can enhance the blood pressure-lowering and dizzy effects of chlorthalidone. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to chlorthalidone or sulfonamide-derived drugs","Anuria (absence of urine production)","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["May cause dizziness; avoid driving or operating machinery until you know how it affects you.","May cause electrolyte imbalances; regular blood tests are recommended.","May increase blood sugar levels; monitor if you have diabetes.","May increase uric acid levels; caution in gout.","May cause photosensitivity; use sun protection.","Do not use potassium supplements or salt substitutes without doctor's advice.","May worsen systemic lupus erythematosus.","Use with caution in elderly patients due to increased risk of electrolyte imbalances and falls."]
🤱 Lactation Safety
Chlorthalidone is excreted in breast milk in small amounts. High doses may suppress lactation. It is generally considered compatible with breastfeeding, but consult your doctor to weigh benefits and risks.
💊 Overdose Management
Overdose of chlorthalidone can cause severe dehydration, electrolyte imbalances, and hypotension. Treatment is supportive and symptomatic. If overdose is suspected, seek emergency medical attention immediately. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before starting this medicine, tell your doctor if you have kidney disease, liver disease, gout, lupus, diabetes, or an allergy to sulfa drugs. This medicine can cause dizziness, so avoid driving or operating heavy machinery until you know how it affects you. Stand up slowly from a sitting or lying position to prevent falls. Drink enough water to stay hydrated, but do not overdo it unless your doctor advises. Avoid alcohol because it can increase dizziness and low blood pressure. Your doctor may ask you to have regular blood tests to check your kidney function, electrolytes, and uric acid levels. Do not take potassium supplements or salt substitutes containing potassium without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking this medicine. Keep all appointments with your doctor and do not skip doses. This medicine may make your skin more sensitive to sunlight, so use sunscreen and protective clothing when outdoors.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of this medicine, especially dizziness, electrolyte imbalances, and dehydration. They may also have reduced kidney function, which can affect drug clearance. Start with a low dose and monitor closely. Regular blood tests and blood pressure checks are recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Chlorthalidone is not recommended for routine use during pregnancy, especially in the first trimester. Your doctor may switch you to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery due to its effects on blood pressure and electrolytes. Follow your doctor's instructions regarding when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or dizziness, which can affect dental procedures. Your dentist may recommend taking a break or adjusting the timing of your dose.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness and electrolyte imbalances, which may affect your exercise tolerance. Stay hydrated during exercise and avoid strenuous activities in hot weather. If you experience dizziness, weakness, or muscle cramps during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, especially when standing up quickly. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause increased urination, so plan your work schedule accordingly. Most people can continue their normal activities with some adjustments.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects such as severe dizziness, fainting, irregular heartbeat, or allergic reactions, seek immediate medical attention. Your doctor may adjust the dose or switch to a different medicine if needed.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to electrolyte imbalances, particularly low potassium and sodium levels. It can also increase blood sugar and uric acid levels, potentially worsening diabetes and gout. Regular monitoring of electrolytes, kidney function, and blood pressure is recommended. In some patients, long-term use may be associated with an increased risk of skin cancer, so sun protection is advised. Periodic review with your doctor is essential to ensure the benefits outweigh the risks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Weight loss, low-sodium diet, exercise, and stress reduction can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, ARBs, calcium channel blockers, and beta-blockers are alternatives or add-ons for hypertension.
Evidence: Well-establishedSome supplements like garlic, hibiscus, and beetroot may have mild blood pressure-lowering effects, but evidence is limited and they can interact with medicines.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for any vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue taking your dose at the same local time as usual, but consult your doctor if you are unsure. Carry enough supply for your entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 2 hours, but it may take several days to weeks to achieve its full blood pressure-lowering effect.
A: It is best to take this medicine in the morning to avoid frequent urination at night. If you must take it at night, consult your doctor.
A: If you remember within 12 hours, take the missed dose. If more than 12 hours have passed, skip it and continue with your regular schedule. Do not double dose.
A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping can cause it to rise again.
A: This medicine may cause mild weight loss due to fluid loss, but it is not a weight-loss medicine. It should only be used for its prescribed indications.
A: Yes, it is often used in combination with other blood pressure medicines, but your doctor will monitor your blood pressure and adjust doses accordingly.
🤔 Common Patient Concerns
🔄 Substitutes for tensiclor 6.25 tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia chlorthalidone 6.25mg tabletDavaindia Generic Pharmacy ₹10.00 66.7% COSTLIER
-
new ch 6.25mg tabletSystopic Laboratories Pvt Ltd ₹16.87 181.2% COSTLIER
-
StayHappi Chlorthalidone 6.25mg TabletSarvagunaushdhi Pvt Ltd ₹16.88 181.3% COSTLIER
-
ctjoy 6.25mg tabletB.J.Healthcare ₹30.00 400% COSTLIER
-
cloridone 6.25mg tabletMaxford Labs Pvt. Ltd. ₹32.06 434.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Chlorthalidone is a water pill that can help you lose weight.
Fact: Chlorthalidone is a diuretic that removes excess fluid, but it is not a weight-loss medicine. It should only be used for its prescribed indications. - Myth: You can stop taking chlorthalidone once your blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping the medicine can cause it to rise again. Continue taking it as prescribed unless your doctor advises otherwise. - Myth: Chlorthalidone is the same as furosemide.
Fact: Both are diuretics, but they belong to different classes and have different potencies and uses. They are not interchangeable. - Myth: Chlorthalidone causes kidney damage.
Fact: Chlorthalidone can cause electrolyte imbalances and dehydration, which may affect kidney function, but it does not directly damage the kidneys when used appropriately and monitored.
🔄 Alternative Options
Generic Alternatives
- Chlorthalidone 6.25 mg tablet (generic)
Brand Alternatives
- Aquiris 6.25mg Tablet
- Hygroton 6.25mg Tablet
- Thalitone 6.25mg Tablet