bitatel m 3d 6.25mg/50mg/40mg tablet - Chlorthalidone (6.25mg) + Metoprolol Succinate (50mg) medicine

Bitatel M 3D 6.25mg/50mg/40mg Tablet - Uses, Price, Side Effects

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🏭 4Care Lifescience Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is bitatel m 3d 6.25mg/50mg/40mg tablet used for?

Bitatel M 3D Tablet is a combination of three medicines: Chlorthalidone (a diuretic), Metoprolol Succinate (a beta-blocker), and Telmisartan (an ARB). It is used to treat hypertension by relaxing blood vessels, reducing fluid volume, and slowing heart rate, thereby lowering blood pressure and reducing risk of stroke and heart attack.

  • Generic Name: Chlorthalidone + Metoprolol Succinate
  • Manufacturer: 4Care Lifescience Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 bitatel m 3d 6.25mg/50mg/40mg tablet Uses & Benefits

Hypertension, heart failure (off-label), angina (off-label).

Off-label uses: Chronic stable angina, migraine prophylaxis (metoprolol), edema (chlorthalidone).

📋 Drug Information

Generic Name(s)Chlorthalidone + Metoprolol Succinate
Brand NameBitatel M 3D 6.25mg/50mg/40mg Tablet
Manufacturer4Care Lifescience Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAntihypertensive combination (Thiazide-like diuretic + Beta-blocker)
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorthalidone: Slowly absorbed from GI tract; Metoprolol: Rapidly and completely absorbed.
DistributionChlorthalidone: Distributed into erythrocytes; Metoprolol: Widely distributed, crosses blood-brain barrier.
Protein BindingChlorthalidone: 75% bound to plasma proteins; Metoprolol: <12% bound.
MetabolismChlorthalidone: Minimal hepatic metabolism; Metoprolol: Extensively metabolized by CYP2D6.
Half-LifeChlorthalidone: 40-60 hours; Metoprolol: 3-7 hours.
ExcretionChlorthalidone: Primarily renal (unchanged); Metoprolol: Renal (metabolites and unchanged drug).
BioavailabilityChlorthalidone: ~65%; Metoprolol: ~50% (first-pass effect).
Onset of ActionChlorthalidone: 2-3 hours; Metoprolol: 1-2 hours.
Peak Plasma TimeChlorthalidone: 2-6 hours; Metoprolol: 1-2 hours.
Duration of ActionChlorthalidone: 24-72 hours; Metoprolol: 12-24 hours.

How It Works

Chlorthalidone: Inhibits sodium reabsorption in distal convoluted tubule; Metoprolol: Selective beta-1 adrenergic receptor antagonist.

Mechanism Steps

1Chlorthalidone inhibits sodium-chloride symporter in distal convoluted tubule, reducing sodium and water reabsorption.
2Metoprolol selectively blocks beta-1 adrenergic receptors in heart, reducing heart rate and contractility.
3Combined effect: decreased cardiac output and reduced peripheral vascular resistance leading to lower blood pressure.

💡 How to Take bitatel m 3d 6.25mg/50mg/40mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⚠️ Side Effects of bitatel m 3d 6.25mg/50mg/40mg tablet

✅ Common Side Effects

Dizziness
Fatigue
Bradycardia
Hypotension
Electrolyte imbalance (hypokalemia, hyponatremia)
Hyperuricemia
GI upset

🚨 Serious Side Effects

Severe bradycardia
Heart block
Bronchospasm
Acute renal failure
Severe hypotension
Digitalis toxicity

⚠️ Rare Side Effects

Thrombocytopenia
Agranulocytosis
Stevens-Johnson syndrome
Hepatic necrosis
Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
NSAIDs Moderate Reduced antihypertensive effect
Digoxin Moderate Increased risk of bradycardia
Lithium Major Increased lithium toxicity risk

🚨 Major Interactions

  • NSAIDs
  • Digitalis glycosides
  • Lithium
  • Other antihypertensives
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)

⚡ Moderate Interactions

  • Antidiabetic agents
  • Corticosteroids
  • Cholestyramine
  • Colestipol
  • Calcium channel blockers (verapamil, diltiazem)

🍷 Alcohol Interaction

May potentiate hypotensive effect; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, sinus bradycardia, heart block, cardiogenic shock, severe hepatic impairment, anuria, uncontrolled heart failure.

🤱 Lactation Safety

Metoprolol excreted in breast milk; chlorthalidone may suppress lactation. Avoid or use with caution

💊 Overdose Management

Gastric lavage, activated charcoal, supportive care; atropine for bradycardia, vasopressors for hypotension.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🔄 Substitutes for bitatel m 3d 6.25mg/50mg/40mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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