Teicokem 200mg Injection - Teicoplanin (200mg) medicine

Targocid 200mg Injection: A Comprehensive Guide to Teicoplanin

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🏭 Alkem Laboratories Ltd 📦 vial of 1 Injection 💊 Allopathy 📅 Updated: Oct 17, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe rash or blistering of skin
  • Decreased urine output or swelling in legs
  • Yellowing of skin or eyes
  • Unusual bleeding or bruising
  • Ringing in ears or hearing loss
  • Severe abdominal pain or persistent diarrhea

If experiencing severe symptoms, call emergency services immediately.

What is Teicokem 200mg Injection used for?

Targocid 200mg injection contains teicoplanin, a glycopeptide antibiotic used to treat serious infections caused by Gram-positive bacteria, including MRSA. It works by breaking down the bacterial cell wall. It is given by injection under medical supervision.

  • Generic Name: Teicoplanin (200mg)
  • Manufacturer: Alkem Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Teicokem 200mg Injection के बारे में (Hindi Summary)

उपयोग: यह दवा टीकोप्लानिन नामक एंटीबायोटिक है, जिसका उपयोग गंभीर जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह मुख्य रूप से ग्राम-पॉजिटिव बैक्टीरिया, जैसे मेथिसिलिन-रेसिस्टेंट स्टैफिलोकोकस ऑरियस (MRSA) के कारण होने वाले संक्रमणों में प्रभावी है। यह दवा त्वचा, हड्डियों, जोड़ों, रक्त और हृदय के संक्रमणों के इलाज में उपयोग की जाती है। यह इंजेक्शन के रूप में डॉक्टर या नर्स द्वारा दी जाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा, दाने, खुजली, बुखार और मतली शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी की प्रतिक्रिया, गुर्दे की समस्या, रक्त विकार और सुनने की क्षमता में कमी शामिल हो सकती है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। उपचार से पहले अपने डॉक्टर को अपनी सभी एलर्जी, गुर्दे की समस्या, सुनने की समस्या या रक्त विकार के बारे में बताएं। उपचार के दौरान गुर्दे की कार्यप्रणाली, यकृत की कार्यप्रणाली और रक्त की निगरानी आवश्यक है। बिना डॉक्टर की सलाह के इस दवा का उपयोग न करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 Teicokem 200mg Injection Uses & Benefits

[{"condition":"Complicated skin and soft tissue infections","description":"Used to treat severe skin infections caused by Gram-positive bacteria, including MRSA.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"Effective in treating osteomyelitis and septic arthritis caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Endocarditis","description":"Used in the treatment of infective endocarditis, especially when caused by resistant Gram-positive bacteria.","evidence":"Well-established"},{"condition":"Hospital-acquired pneumonia","description":"May be used for pneumonia acquired in hospital settings, including ventilator-associated pneumonia.","evidence":"Moderate"},{"condition":"Bloodstream infections","description":"Used for bacteremia caused by Gram-positive bacteria, including MRSA.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Clostridioides difficile infection","description":"Sometimes used orally for severe C. difficile colitis, though not FDA-approved for this indication.","evidence":"Limited"},{"condition":"Prosthetic joint infections","description":"Used in combination with other antibiotics for prosthetic joint infections, often as part of a broader regimen.","evidence":"Limited"}]

Primary treatment for: Serious Gram-positive bacterial infections

Also treats: MRSA infections, Enterococcal infections, Streptococcal infections

📋 Drug Information

Generic Name(s)Teicoplanin (200mg)
Brand NameTeicokem 200mg Injection
ManufacturerAlkem Laboratories Ltd
Packaging / Formvial of 1 Injection (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationParenteral (intravenous or intramuscular injection)
StorageStore at room temperature (15-30°C). Protect from light. Do not freeze. Once reconstituted, use immediately or store as directed by the manufacturer.
Shelf LifeRefer to the packaging for the expiration date. Do not use after the expiry date.
WHO GuidelineTeicoplanin is included in the WHO Model List of Essential Medicines for the treatment of serious Gram-positive infections.
ICMR GuidelineICMR guidelines recommend teicoplanin as an alternative to vancomycin for MRSA infections, especially when vancomycin is not suitable.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always administer this medicine under medical supervision; it is not for self-administration.
2
Monitor kidney function regularly, especially in elderly patients or those on other nephrotoxic drugs.
3
Watch for signs of allergic reactions during infusion; have emergency equipment ready.
4
Adjust dose in renal impairment to avoid toxicity.
5
Educate patients to report any hearing changes, ringing in ears, or decreased urine output immediately.
6
Ensure the full course is completed to prevent resistance.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Severe skin infection with redness and swelling
This medicine is commonly prescribed for this.
Likely Use
✅
Fever with joint pain
May be used if bacterial infection is suspected.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered parenterally and is completely absorbed after intravenous or intramuscular injection. Oral absorption is poor, so it is not given orally for systemic infections.
DistributionThis medicine distributes widely into body tissues, including skin, bone, and joint fluid. It has a high volume of distribution, approximately 0.7-1.4 L/kg. It does not penetrate the cerebrospinal fluid well unless the meninges are inflamed.
Protein BindingApproximately 90-95% bound to plasma proteins.
MetabolismThis medicine is not metabolized significantly and is excreted largely unchanged.
Half-LifeThe elimination half-life is approximately 100-170 hours, which allows for once-daily dosing after a loading dose.
ExcretionThis medicine is primarily excreted unchanged in the urine via glomerular filtration. Renal impairment significantly affects its elimination.
Bioavailability100% for intravenous administration; approximately 90% for intramuscular administration.
Onset of ActionThe onset of action is within 30-60 minutes after intravenous administration.
Peak Plasma TimePeak plasma concentrations are reached immediately after intravenous injection and within 2 hours after intramuscular injection.
Duration of ActionThe duration of action is prolonged due to the long half-life, allowing for once-daily dosing.

How It Works

This medicine inhibits bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of peptidoglycan precursors. This prevents the cross-linking of peptidoglycan chains, leading to a weakened cell wall and bacterial cell death. It is bactericidal against susceptible Gram-positive bacteria.

Mechanism Steps

1
Binding to target: This medicine binds to the D-alanyl-D-alanine terminus of peptidoglycan precursors on the bacterial cell wall.
2
Inhibition of cross-linking: This binding prevents the cross-linking of peptidoglycan chains, which are essential for cell wall integrity.
3
Cell wall weakening: The bacterial cell wall becomes weak and unable to withstand osmotic pressure.
4
Bacterial cell death: The weakened cell wall leads to cell lysis and death of the bacteria.

💡 How to Take Teicokem 200mg Injection

Strength: 200mg lyophilized powder for injection

1This medicine is administered by a healthcare professional.
2It is given as an intravenous (IV) injection or infusion, or intramuscular (IM) injection.
3The injection site will be cleaned before administration.
4For IV infusion, the medicine is diluted and given over 30-60 minutes.
5For IM injection, it is given into a large muscle.
6Do not self-administer this medicine.

Dosage Information

Adult DosageThe usual adult dose is 400mg or 6mg/kg intravenously every 24 hours for most infections, after an initial loading dose of 400mg or 6mg/kg every 12 hours for 3 to 5 doses. For severe infections, a higher dose may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced kidney function and may require dose adjustment. Monitor kidney function closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For creatinine clearance 40-60 mL/min, dose may be reduced or interval extended. For severe renal impairment, consult a specialist. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentNo specific dose adjustment is recommended for hepatic impairment, but monitor liver function. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum daily dose is not established from available information. Doses up to 12mg/kg/day have been used in severe infections under specialist supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Teicokem 200mg Injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress to the site. Report if severe or persistent.
Rash (Common (5-10%))
Monitor for progression. Consult doctor if rash spreads or is accompanied by fever.
Itching (Common (5-10%))
Avoid scratching. Consult doctor if persistent.
Fever (Common (5-10%))
Stay hydrated. Consult doctor if fever persists or is high.
Nausea (Common (5-10%))
Take small, frequent meals. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience difficulty breathing, swelling of the face or throat, or a severe rash.
Kidney damage (nephrotoxicity) (Uncommon (0.1-1%))
Regular monitoring of kidney function is required. Report decreased urine output or swelling.
Blood disorders (e.g., neutropenia, thrombocytopenia) (Uncommon (0.1-1%))
Regular blood tests are necessary. Report unusual bruising or bleeding.
Hearing loss (ototoxicity) (Rare (<0.1%))
Report any ringing in the ears or hearing difficulty immediately.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Rare (<0.1%))
Seek immediate medical attention if you develop a painful rash, blisters, or peeling skin.

⚠️ Rare Side Effects

Liver toxicity
Report yellowing of skin or eyes, dark urine, or abdominal pain.
Seizures
Seek immediate medical attention if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Gentamicin Major
Amphotericin B Major
Cyclosporine Major
Colistin Major
Furosemide Moderate
NSAIDs Moderate
Warfarin Minor

🚨 Major Interactions

  • Aminoglycosides (e.g., gentamicin)
  • Amphotericin B
  • Cyclosporine
  • Colistin

⚡ Moderate Interactions

  • Loop diuretics (e.g., furosemide)
  • NSAIDs

🍷 Alcohol Interaction

Alcohol may increase the risk of liver toxicity and should be avoided during treatment with this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to teicoplanin or any component of the formulation","Previous severe allergic reaction to vancomycin or other glycopeptides"]

⚠️ Warnings & Precautions

["Administer with caution in patients with renal impairment. Dose adjustment is required.","Monitor kidney function regularly, especially in elderly patients and those on other nephrotoxic drugs.","May cause ototoxicity; monitor hearing if used for prolonged periods or with other ototoxic drugs.","May cause blood disorders; monitor blood counts regularly.","Serious allergic reactions, including anaphylaxis, can occur. Have appropriate medical support available during administration.","Not effective against Gram-negative bacteria. Consider combination therapy for mixed infections.","Avoid rapid intravenous injection to reduce risk of histamine release (red man syndrome)."]

🤱 Lactation Safety

This medicine is excreted in breast milk in small amounts. It should be used with caution during breastfeeding. Consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose may increase the risk of kidney damage and hearing loss. Treatment is supportive and symptomatic. Teicoplanin is not removed by hemodialysis or peritoneal dialysis. Monitor kidney function and hearing closely.

⏰ Missed Dose

If a dose is missed, contact your healthcare provider as soon as possible. Do not double the dose to catch up. The dosing schedule should be adjusted by your doctor.

Additional Safety Advice

General Safety

This medicine should only be administered by a qualified healthcare professional. Patients should inform their doctor about any allergies, kidney problems, hearing issues, or blood disorders before receiving this medicine. Regular monitoring of kidney function, liver function, and blood counts is essential during treatment. Avoid using this medicine without a prescription. Do not self-administer. Report any signs of allergic reaction, such as difficulty breathing, swelling of the face or throat, or severe rash, immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of kidney damage and hearing loss. Dose adjustment based on kidney function is often required. Close monitoring is essential.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before starting this medicine. It should be used during pregnancy only if clearly needed. Discuss risks and benefits.

🏥 Post-Surgery Considerations

This medicine may be used to treat or prevent surgical site infections. It is administered under medical supervision. Follow your surgeon's instructions for wound care.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures. No specific precautions, but maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help your kidneys flush out the medicine.
🥗
Maintain good hygiene to prevent reinfection.
😴
Eat a balanced diet to support your immune system.
💧
Get plenty of rest to aid recovery.
🧘
Avoid alcohol as it may increase liver toxicity risk.
🌞
Report any new symptoms to your doctor promptly.

🏋️ Exercise Considerations

Avoid strenuous exercise during treatment, especially if you have joint or bone infections. Consult your doctor before resuming exercise.

🥗 Diet Recommendations

Drink plenty of water
Include protein-rich foods to aid healing
Avoid alcohol
Eat fruits and vegetables rich in vitamins

💼 Impact on Daily Work & Life

This medicine is given in a hospital or clinic setting, so it may require time off work for administration. You may feel tired or have mild side effects, but most people can resume normal activities as tolerated.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Stopping early may lead to recurrence of infection and antibiotic resistance. Your doctor will determine the appropriate duration based on your condition.

📅 Long-Term Use Effects

Long-term use may increase the risk of kidney damage, hearing loss, and blood disorders. Regular monitoring of kidney function, liver function, blood counts, and hearing is recommended. The medicine should be used for the shortest duration necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Vancomycin

Another glycopeptide antibiotic for similar infections.

Evidence: Well-established
Daptomycin

Alternative for Gram-positive infections, especially skin and bloodstream.

Evidence: Well-established
Linezolid

Oral option for some Gram-positive infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions reported. However, ensure routine vaccinations are up to date. Live vaccines should be avoided during active infection.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. It should be stored at room temperature and protected from light. If traveling across time zones, consult your doctor for dose adjustment. Declare it at customs if required. Keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 65-year-old man with a prosthetic joint infection caused by MRSA
He was started on this medicine after vancomycin caused kidney problems. The infection improved over several weeks, and his kidney function remained stable with dose adjustment. He completed the full course and recovered well.
💡 Lesson: Teicoplanin can be an effective alternative for patients who cannot tolerate vancomycin, but kidney function must be monitored closely.
👤 A 45-year-old woman with a severe skin infection (cellulitis) caused by MRSA
She received this medicine intravenously for 10 days. Her fever subsided within 3 days, and the redness and swelling decreased gradually. She experienced mild injection site pain but no serious side effects.
💡 Lesson: Teicoplanin is effective for serious skin infections, and side effects are usually manageable.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvement in symptoms may be seen within 48-72 hours, but the full course must be completed.

Q: Can I take this medicine at home?

A: No, it must be administered by a healthcare professional in a clinical setting.

Q: Is it safe during pregnancy?

A: Consult your doctor; it should be used only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine if I have kidney problems?
  • Will this medicine affect my hearing?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Teicokem 200mg Injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Targocid 200mg injection can cure any infection.
    Fact: This medicine is only effective against Gram-positive bacteria and is not used for viral infections or Gram-negative infections.
  • Myth: Targocid 200mg injection is safe for everyone.
    Fact: It can cause serious side effects and requires monitoring, especially in patients with kidney problems.
  • Myth: You can stop taking Targocid 200mg injection once you feel better.
    Fact: You must complete the full course as prescribed by your doctor to prevent recurrence and resistance.

🔄 Alternative Options

Generic Alternatives

  • Teicoplanin

Brand Alternatives

  • Targocid

📊 Comparison with Similar Medicines

[{"medicine":"Teicoplanin","class":"Glycopeptide","route":"Parenteral","half_life":"100-170 hours","common_use":"MRSA infections"},{"medicine":"Vancomycin","class":"Glycopeptide","route":"Parenteral","half_life":"4-6 hours","common_use":"MRSA infections"},{"medicine":"Daptomycin","class":"Lipopeptide","route":"Parenteral","half_life":"8-9 hours","common_use":"Skin infections, bacteremia"}]

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