Megalis 20 Tablet: Comprehensive Guide to Uses, Dosage, and Safety
When to Call Your Doctor IMMEDIATELY
- Erection lasting more than 4 hours
- Sudden loss of vision in one or both eyes
- Sudden decrease or loss of hearing
- Chest pain, shortness of breath, or fainting
- Severe dizziness or lightheadedness
- Swelling of face, lips, tongue, or throat
- Rash or hives
If experiencing severe symptoms, call emergency services immediately.
What is tadact 20 tablet used for?
This medicine contains Tadalafil 20 mg, a PDE5 inhibitor used to treat erectile dysfunction and pulmonary arterial hypertension. It works by increasing blood flow to the penis or lungs. It should not be taken with nitrates.
- Generic Name: Tadalafil (20mg)
- Manufacturer: Ipca Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 tadact 20 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टैडालाफिल 20 मिलीग्राम युक्त एक प्रिस्क्रिप्शन टैबलेट है। इसका उपयोग पुरुषों में स्तंभन दोष (इरेक्टाइल डिसफंक्शन) के इलाज के लिए किया जाता है। यह फुफ्फुसीय धमनी उच्च रक्तचाप (पल्मोनरी आर्टेरियल हाइपरटेंशन) के इलाज में भी प्रयोग की जाती है। यह दवा रक्त वाहिकाओं को आराम देकर रक्त प्रवाह बढ़ाती है, जिससे यौन उत्तेजना के दौरान स्तंभन प्राप्त करने और बनाए रखने में मदद मिलती है। यह दवा नाइट्रेट्स या रियोसिगुआट के साथ नहीं लेनी चाहिए क्योंकि इससे रक्तचाप खतरनाक रूप से गिर सकता है। यह दवा महिलाओं और बच्चों के लिए नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चेहरे पर लालिमा, अपच, नाक बंद होना, पीठ दर्द, मांसपेशियों में दर्द और चक्कर आना शामिल हैं। ये आमतौर पर हल्के से मध्यम होते हैं और समय के साथ कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें अचानक दृष्टि हानि, सुनने में कमी, प्रियापिज्म (4 घंटे से अधिक स्तंभन), और नाइट्रेट्स के साथ लेने पर गंभीर निम्न रक्तचाप शामिल हो सकते हैं। इनमें से कोई भी लक्षण दिखने पर तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। 24 घंटे में एक से अधिक खुराक न लें। अत्यधिक शराब के सेवन से बचें क्योंकि इससे चक्कर आना और निम्न रक्तचाप का खतरा बढ़ सकता है। नाइट्रेट्स, रियोसिगुआट या किसी अन्य PDE5 अवरोधक के साथ यह दवा न लें। अपने डॉक्टर को सभी अन्य दवाओं के बारे में बताएं। यदि आपको हृदय रोग, यकृत या गुर्दे की समस्या है तो डॉक्टर को बताएं। चक्कर आने पर वाहन न चलाएं। कमरे के तापमान पर सूखी जगह पर रखें। बच्चों की पहुंच से दूर रखें।
💊 tadact 20 tablet Uses & Benefits
[{"condition":"Erectile Dysfunction","description":"This medicine helps men achieve and maintain an erection sufficient for sexual activity by increasing blood flow to the penis when sexually stimulated.","evidence":"Well-established"},{"condition":"Pulmonary Arterial Hypertension","description":"At this strength, this medicine is used to improve exercise ability and delay clinical worsening in adults with pulmonary arterial hypertension (WHO Group I).","evidence":"Well-established"},{"condition":"Benign Prostatic Hyperplasia (BPH) with Erectile Dysfunction","description":"Sometimes used to treat lower urinary tract symptoms associated with BPH in men who also have erectile dysfunction.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Raynaud's Phenomenon","description":"Occasionally prescribed off-label to improve blood flow in fingers and toes in people with Raynaud's phenomenon.","evidence":"Limited"},{"condition":"High Altitude Pulmonary Edema Prevention","description":"Rarely used off-label for prevention of high altitude pulmonary edema, but evidence is not strong.","evidence":"Limited"}]
Primary treatment for: Erectile Dysfunction
Also treats: Pulmonary Arterial Hypertension, Benign Prostatic Hyperplasia
📋 Drug Information
| Generic Name(s) | Tadalafil (20mg) |
| Brand Name | tadact 20 tablet |
| Manufacturer | Ipca Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | SEX STIMULANTS REJUVENATORS |
| Action Class | Phosphodiesterase-V inhibitors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and heat. Do not refrigerate. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). By inhibiting PDE5, it prevents the breakdown of cGMP in smooth muscle cells of the corpus cavernosum and pulmonary vasculature. This leads to relaxation of smooth muscle and increased blood flow, which is essential for erection and for lowering pulmonary arterial pressure.
Mechanism Steps
💡 How to Take tadact 20 tablet
Strength: Tablet, 20 mg
Dosage Information
| Adult Dosage | For erectile dysfunction, the usual recommended dose is 10 mg taken at least 30 minutes before sexual activity, but the dose may be increased to 20 mg or decreased to 5 mg based on individual response and tolerability. The maximum recommended dosing frequency is once per day. For pulmonary arterial hypertension, the recommended dose is 40 mg once daily, but this 20 mg tablet is not the standard strength for that indication. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No dose adjustment is required based on age alone. However, elderly patients may be more sensitive to the effects of this medicine, especially hypotension. Use with caution and monitor blood pressure. |
| Renal Impairment | No dose adjustment is needed for mild to moderate renal impairment. In severe renal impairment (creatinine clearance <30 mL/min), a lower starting dose may be considered. Consult your doctor. |
| Hepatic Impairment | No dose adjustment is needed for mild to moderate hepatic impairment. In severe hepatic impairment (Child-Pugh Class C), the dose should not exceed 10 mg once daily. Consult your doctor. |
| Maximum Daily Dose | 20 mg once daily for erectile dysfunction. For pulmonary arterial hypertension, the maximum dose is 40 mg once daily, but this 20 mg tablet is not the standard strength for that indication. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of tadact 20 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Nitrates | Major | |
| Riociguat | Major | |
| Ketoconazole | Major | |
| Ritonavir | Major | |
| Alpha-blockers | Moderate | |
| Rifampin | Moderate | |
| Antihypertensives | Moderate | |
| Grapefruit juice | Moderate | |
| Antacids | Minor | |
| Aspirin | Minor |
🚨 Major Interactions
- Nitrates (e.g., nitroglycerin, isosorbide mononitrate)
- Riociguat
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
- Alpha-blockers (e.g., doxazosin, tamsulosin)
⚡ Moderate Interactions
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- Antihypertensives
- Grapefruit juice
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, headache, and low blood pressure when taken with this medicine. It is advisable to limit or avoid alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Concomitant use of nitrates","Concomitant use of riociguat","Known hypersensitivity to tadalafil or any component of the tablet","Recent myocardial infarction (within last 90 days)","Unstable angina or angina during sexual intercourse","Severe heart failure","Uncontrolled arrhythmias","Hypotension (blood pressure
⚠️ Warnings & Precautions
["This medicine does not protect against sexually transmitted infections. Use barrier methods.","Seek immediate medical help if you experience an erection lasting more than 4 hours.","Do not take this medicine if you are taking nitrates for chest pain.","Use with caution in patients with bleeding disorders or active peptic ulcer.","Avoid driving or operating machinery if you feel dizzy after taking this medicine.","Inform your doctor if you have a history of vision problems, especially NAION.","Do not take this medicine if you have been advised not to have sexual activity due to heart problems."]
🤱 Lactation Safety
Not applicable. This medicine is not indicated for use in women.
💊 Overdose Management
Overdose of this medicine may cause severe hypotension, syncope, and priapism. Treatment should be supportive and symptomatic. In case of overdose, seek immediate medical attention. Hemodialysis is not expected to be effective in removing tadalafil from the body.
⏰ Missed Dose
This medicine is usually taken on an as-needed basis for erectile dysfunction. If you are taking it daily for pulmonary arterial hypertension and miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than one dose in 24 hours. Avoid drinking large amounts of alcohol, as it can increase the risk of dizziness and low blood pressure. Do not take this medicine with nitrates, riociguat, or any other PDE5 inhibitor. Inform your doctor about all other medicines you are taking, especially for blood pressure, fungal infections, or HIV. Tell your doctor if you have heart disease, liver or kidney problems, or a history of stroke. Do not drive or operate heavy machinery if you feel dizzy after taking this medicine. Store it at room temperature away from moisture and heat. Keep out of reach of children. If you experience an erection lasting more than four hours, seek emergency medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially hypotension and dizziness. Use with caution and monitor blood pressure. No dose adjustment is required based on age alone, but individualization is advised.
🤰 Pregnancy Planning (TTC)
This medicine is not indicated for use in women. It does not affect female fertility. For men, it does not affect sperm production or fertility.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, especially if you have recently had cardiovascular surgery or are taking medications that affect blood pressure. It is contraindicated in patients with recent myocardial infarction.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, especially if you are scheduled for dental surgery. It may interact with medications used during dental procedures, such as nitrates or anesthetics. Your dentist may advise you to stop it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness or low blood pressure. Avoid strenuous exercise if you feel dizzy or lightheaded. Consult your doctor before starting any new exercise program, especially if you have heart or lung disease.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or vision changes in some people. Do not drive or operate heavy machinery if you experience these effects. Otherwise, it should not affect your ability to work. For pulmonary arterial hypertension, it may improve exercise capacity and quality of life.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, especially if you are taking it for pulmonary arterial hypertension. If you experience serious side effects, seek medical advice immediately. For erectile dysfunction, you may stop taking it if you no longer need it, but consult your doctor for any concerns.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well-tolerated. However, regular monitoring of blood pressure, renal and hepatic function may be advised, especially in patients with underlying conditions. There is no evidence of tolerance or dependence with long-term use. For pulmonary arterial hypertension, long-term use has been shown to improve exercise capacity and delay clinical worsening.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Weight loss, exercise, and smoking cessation can improve erectile dysfunction and overall health.
Evidence: Well-establishedCounseling can help with psychological causes of erectile dysfunction.
Evidence: Well-establishedMechanical devices can help achieve an erection.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccination considerations are associated with this medicine. However, maintaining up-to-date vaccinations is important for overall health.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from moisture and heat. If crossing time zones, adjust the timing of daily doses for pulmonary arterial hypertension in consultation with your doctor. For as-needed use, take it at least 30 minutes before sexual activity. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts working within 30 to 60 minutes after taking it, but it requires sexual stimulation to produce an erection.
A: The effect can last up to 36 hours, which is why it is sometimes called the 'weekend pill'.
A: For erectile dysfunction, it is usually taken as needed, not more than once daily. For pulmonary arterial hypertension, it is taken daily as prescribed.
A: Avoid nitrates, riociguat, and excessive alcohol. Also avoid grapefruit juice in large amounts.
A: This medicine can cause hypotension and should be used with caution in patients with heart disease. It is contraindicated in certain heart conditions. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for tadact 20 tablet
View AllAlternative brands with exact same active ingredient:
-
stayhappi tadalafil 20mg tabletSarvagunaushdhi Pvt Ltd ₹8.33 97.7% CHEAPER
-
tada 20mg tabletLupin Ltd ₹23.73 93.5% CHEAPER
-
ed save 20 orally disintegrating stripFourrts India Laboratories Pvt Ltd ₹36.56 89.9% CHEAPER
-
longtid 20 tabletRockmed Pharma Pvt. Ltd. ₹42.19 88.4% CHEAPER
-
tadasure 20mg tabletLinux Laboratories ₹48.75 86.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is an aphrodisiac.
Fact: This medicine does not cause sexual arousal. It requires sexual stimulation to work. - Myth: This medicine can be taken with nitrates.
Fact: This medicine is contraindicated with nitrates due to the risk of severe hypotension. - Myth: This medicine is safe for everyone.
Fact: This medicine is not for women or children and has several contraindications.
🔄 Alternative Options
Generic Alternatives
- Tadalafil 20 mg tablet
Brand Alternatives
- Megalis 20 Tablet