Assurans Tablet (Sildenafil 20mg): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Sudden vision loss in one or both eyes
- Sudden hearing loss or ringing in the ears
- Chest pain or difficulty breathing
- Prolonged erection lasting more than 4 hours
- Severe dizziness or fainting
- Signs of an allergic reaction such as rash, itching, swelling of face or throat
If experiencing severe symptoms, call emergency services immediately.
What is assurans tablet used for?
This medicine contains sildenafil 20 mg, a PDE5 inhibitor used to treat pulmonary arterial hypertension (PAH) in adults. It works by relaxing blood vessels in the lungs to improve blood flow and exercise capacity. It is taken orally three times daily.
- Generic Name: Sildenafil
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 assurans tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सिल्डेनाफिल 20 मिलीग्राम युक्त एक प्रिस्क्रिप्शन टैबलेट है, जिसका उपयोग फुफ्फुसीय धमनी उच्च रक्तचाप (PAH) के इलाज के लिए किया जाता है। यह फेफड़ों की रक्त वाहिकाओं को आराम देकर रक्त प्रवाह में सुधार करती है और व्यायाम क्षमता बढ़ाती है। इसे दिन में तीन बार लिया जाता है।
साइड इफेक्ट्स: सामान्य दुष्प्रभावों में सिरदर्द, चेहरे पर लालिमा, अपच, नाक बंद होना और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में निम्न रक्तचाप, बेहोशी और दृष्टि परिवर्तन शामिल हो सकते हैं। यदि अचानक दृष्टि हानि, सीने में दर्द या लंबे समय तक इरेक्शन हो तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। नाइट्रेट्स या रियोसिगुआट के साथ इसका सेवन न करें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। शराब से बचें क्योंकि इससे निम्न रक्तचाप का खतरा बढ़ सकता है। इसे कमरे के तापमान पर सूखी जगह पर रखें।
💊 assurans tablet Uses & Benefits
[{"condition":"Pulmonary Arterial Hypertension (PAH)","description":"This medicine is indicated to improve exercise ability and delay clinical worsening in adults with PAH (WHO Group I).","evidence":"Well-established"}]
Off-label uses: [{"condition":"Raynaud's phenomenon","description":"Sometimes prescribed off-label to improve blood flow in fingers and toes.","evidence":"Limited"},{"condition":"High-altitude pulmonary edema prevention","description":"May be used off-label to prevent fluid accumulation in lungs at high altitudes.","evidence":"Limited"}]
Primary treatment for: Pulmonary Arterial Hypertension (PAH)
Also treats: Raynaud's phenomenon, High-altitude pulmonary edema
📋 Drug Information
| Generic Name(s) | Sildenafil |
| Brand Name | Assurans Tablet |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | SEX STIMULANTS REJUVENATORS |
| Action Class | Phosphodiesterase-V inhibitors |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) away from moisture and heat. Keep in original container. |
| Shelf Life | 24 months from date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine inhibits phosphodiesterase type 5 (PDE5), the enzyme responsible for breaking down cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the pulmonary vasculature. By inhibiting PDE5, it increases cGMP levels, leading to relaxation of smooth muscle and vasodilation. This results in reduced pulmonary arterial pressure and improved blood flow.
Mechanism Steps
💡 How to Take assurans tablet
Strength: 20 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The recommended dose for pulmonary arterial hypertension is 20 mg taken three times daily, approximately 4 to 6 hours apart. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but use with caution due to potential for increased sensitivity. |
| Renal Impairment | No dose adjustment is required for mild to moderate renal impairment. In severe renal impairment (creatinine clearance <30 mL/min), use with caution and consider dose reduction. |
| Hepatic Impairment | No dose adjustment is required for mild to moderate hepatic impairment. In severe hepatic impairment (Child-Pugh C), the dose should not exceed 20 mg once daily. |
| Maximum Daily Dose | 60 mg per day (20 mg three times daily). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of assurans tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Nitrates | Major | |
| Riociguat | Major | |
| Alpha-blockers | Major | |
| CYP3A4 inhibitors | Moderate | |
| CYP3A4 inducers | Moderate | |
| Antihypertensives | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Nitrates (e.g., nitroglycerin, isosorbide mononitrate)
- Riociguat
- Alpha-blockers (e.g., doxazosin, terazosin)
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- Antihypertensives
🍷 Alcohol Interaction
Alcohol may increase the risk of hypotension and dizziness. Avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Concomitant use of nitrates","Concomitant use of riociguat","Hypersensitivity to sildenafil or any component","Recent stroke or myocardial infarction","Severe hypotension"]
⚠️ Warnings & Precautions
["Cardiovascular risk: Assess cardiovascular status before initiating therapy.","Priapism: Prolonged erections may occur. Seek immediate medical attention if erection lasts >4 hours.","NAION: Sudden vision loss has been reported. Discontinue and seek medical attention.","Hearing loss: Sudden decrease or loss of hearing has been reported.","Hypotension: Use with caution in patients with low blood pressure or on antihypertensives.","Hepatic impairment: Dose adjustment may be needed in severe hepatic impairment.","Renal impairment: Dose adjustment may be needed in severe renal impairment."]
🤱 Lactation Safety
Not established from the available information. This medicine is not indicated for use in breastfeeding women.
💊 Overdose Management
In case of overdose, seek immediate medical attention. Treatment should be supportive and symptomatic. Hemodialysis is not expected to be effective due to high protein binding.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. Avoid taking nitrates or riociguat while on this medicine. Inform your doctor about all other medicines you are taking, especially alpha-blockers, antihypertensives, and CYP3A4 inhibitors. Use caution when driving or operating machinery until you know how this medicine affects you. Avoid drinking alcohol as it may increase the risk of low blood pressure. Store at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Use with caution and monitor blood pressure regularly.
🤰 Pregnancy Planning (TTC)
This medicine is not indicated for use in women, including during pregnancy planning. Consult your doctor for alternative treatments if you are pregnant or planning to become pregnant.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with medications used during surgery and affect blood pressure.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, especially if you are undergoing procedures that may cause bleeding or require anesthesia.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until you know how this medicine affects you. Start slowly and gradually increase activity as tolerated. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or hypotension, which can affect your ability to drive or operate machinery. Use caution until you know how it affects you. Most people can continue their normal activities with appropriate precautions.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as vision loss or prolonged erection, seek immediate medical attention and follow your doctor's advice.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well-tolerated. Regular monitoring of blood pressure, vision, and hearing is advised. Some patients may develop tolerance, but this is uncommon. Do not stop taking this medicine without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another PDE5 inhibitor with a longer duration of action, taken once daily.
Evidence: Well-establishedAlternative class for PAH, often used in combination.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any live vaccines while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. When crossing time zones, adjust dosing times gradually in consultation with your doctor. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 to 60 minutes, but its full benefits for pulmonary arterial hypertension may take several weeks to become noticeable.
A: No, taking this medicine with nitrates can cause a severe drop in blood pressure. It is contraindicated.
A: Yes, it is generally safe for long-term use under medical supervision. Regular monitoring of blood pressure and vision is recommended.
🤔 Common Patient Concerns
🔄 Substitutes for assurans tablet
View AllAlternative brands with exact same active ingredient:
-
sildaflow 20mg tabletMankind Pharma Ltd ₹100.00 76% CHEAPER
-
pulmoday 20mg tabletAprica Pharmaceuticals Pvt Ltd ₹155.36 62.7% CHEAPER
-
esylnafil 20mg tabletTruecure Healthcare Private Limited ₹180.00 56.8% CHEAPER
-
pah 20 tabletMSN Laboratories ₹292.59 29.8% CHEAPER
-
penegra pah tabletZydus Cadila ₹300.00 28.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is only for erectile dysfunction.
Fact: This medicine is also approved for pulmonary arterial hypertension at a lower dose. - Myth: This medicine can be taken with nitrates.
Fact: Combining with nitrates can cause severe hypotension and is contraindicated.
🔄 Alternative Options
Generic Alternatives
- Sildenafil 20 mg tablet
Brand Alternatives
- Revatio
- Viagra