Taboran P 100 mg/500 mg Tablet - Diclofenac (100mg) + Paracetamol (500mg) medicine

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🏭 Adventus Laboratories India Pvt Ltd 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Diclofenac is generally avoided in the third trimester due to risk of premature closure of ductus arteriosus. Paracetamol is considered relatively safe in pregnancy when used at recommended doses. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for short-term pain relief.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is Taboran P 100 mg/500 mg Tablet used for?

This medicine is a combination of diclofenac and paracetamol used for short-term relief of moderate to severe pain and inflammation. It works by reducing prostaglandins that cause pain and fever. Take it with food to avoid stomach upset and do not exceed the prescribed dose.

  • Generic Name: Diclofenac (100mg) + Paracetamol (500mg)
  • Manufacturer: Adventus Laboratories India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Taboran P 100 mg/500 mg Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डाइक्लोफेनाक और पैरासिटामोल का संयोजन है, जिसका उपयोग मध्यम से गंभीर दर्द और सूजन के अल्पकालिक उपचार के लिए किया जाता है। यह ऑस्टियोआर्थराइटिस, रुमेटॉइड आर्थराइटिस, एंकिलोजिंग स्पॉन्डिलाइटिस, मांसपेशियों की चोट, और सर्जरी के बाद के दर्द में राहत देती है। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। इस दवा को डॉक्टर की सलाह के बिना न लें और न ही अधिक मात्रा में लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, यकृत की क्षति, और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के निर्देशानुसार ही लें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और यकृत की क्षति का खतरा बढ़ सकता है। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या गुर्दे/यकृत की बीमारी है, तो डॉक्टर से सलाह लें। दवा को कमरे के तापमान पर सूखी जगह पर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 Taboran P 100 mg/500 mg Tablet Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate back pain and stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute musculoskeletal injuries","description":"Provides short-term relief for sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for management of moderate to severe pain after surgical procedures.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Renal colic","description":"May be used off-label for pain relief in kidney stones, but NSAIDs are used with caution.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation

Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute musculoskeletal injuries, Post-operative pain, Dysmenorrhea

📋 Drug Information

Generic Name(s)Diclofenac (100mg) + Paracetamol (500mg)
Brand NameTaboran P 100 mg/500 mg Tablet
ManufacturerAdventus Laboratories India Pvt Ltd
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the prescribed dose; taking more can cause liver and kidney damage.
3
Avoid alcohol and other NSAIDs while taking this medicine.
4
Stay well hydrated throughout the day to support kidney function.
5
Consult your doctor if pain persists beyond 7 days or worsens.
6
Report any unusual bleeding, bruising, or dark stools immediately.
7
Do not drive or operate machinery if you feel dizzy or drowsy.
8
Inform your doctor about all other medications you are taking.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Acute muscle injury
This medicine can provide short-term relief.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDiclofenac is rapidly and completely absorbed from the gastrointestinal tract after oral administration. Paracetamol is also rapidly absorbed from the gastrointestinal tract. Food may delay the absorption of diclofenac but does not significantly affect the extent of absorption. The presence of food may reduce gastrointestinal side effects.
DistributionDiclofenac is highly bound to plasma proteins (approximately 99%) and distributes widely into tissues, including synovial fluid. Paracetamol is distributed throughout most body tissues, with a volume of distribution of approximately 0.95 L/kg. It crosses the placenta and is excreted in breast milk.
Protein BindingDiclofenac: Approximately 99% bound to plasma proteins, primarily albumin. Paracetamol: Approximately 10-25% bound to plasma proteins.
MetabolismDiclofenac is metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C9, to several metabolites, including 4'-hydroxydiclofenac. Paracetamol is metabolized in the liver primarily by glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified by glutathione.
Half-LifeDiclofenac: Approximately 1-2 hours. Paracetamol: Approximately 2-3 hours.
ExcretionDiclofenac is excreted primarily in urine (about 65%) and bile (about 35%) as metabolites. Paracetamol is excreted in urine as glucuronide and sulfate conjugates, with less than 5% excreted unchanged.
BioavailabilityDiclofenac: Approximately 50-60% due to first-pass metabolism. Paracetamol: Approximately 80-90%.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration.
Peak Plasma TimeDiclofenac: 1-2 hours. Paracetamol: 0.5-1 hour.
Duration of ActionPain relief lasts approximately 4-6 hours, but may be longer with the combination.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Diclofenac is a non-selective NSAID that reversibly inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, leading to decreased synthesis of prostaglandins, prostacyclin, and thromboxane. This results in reduced inflammation, pain, and fever. Paracetamol (acetaminophen) acts predominantly in the central nervous system by inhibiting prostaglandin synthesis, although its exact mechanism is not fully elucidated. It also has antipyretic effects through action on the hypothalamic heat-regulating center. The combination provides enhanced analgesic and anti-inflammatory effects compared to either agent alone.

Mechanism Steps

1
Inhibition of cyclooxygenase enzymes: Diclofenac binds to and reversibly inhibits COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: Decreased production of prostaglandins, prostacyclin, and thromboxane leads to reduced inflammation, pain, and fever.
3
Central analgesic action of paracetamol: Paracetamol acts on the central nervous system to inhibit prostaglandin synthesis, possibly via COX-3, and modulates pain perception.
4
Antipyretic effect: Paracetamol acts on the hypothalamus to reduce fever by promoting heat loss.
5
Additive analgesic effect: The combination of peripheral and central mechanisms results in enhanced pain relief compared to either drug alone.

💡 How to Take Taboran P 100 mg/500 mg Tablet

Strength: Immediate-release tablet containing Diclofenac 100 mg and Paracetamol 500 mg.

1Take this medicine orally with a full glass of water.
2Take with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Do not lie down immediately after taking the tablet.
5Follow the prescribed dosing schedule exactly.
6Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet two to three times daily, depending on the severity of pain and the patient's response. The maximum recommended dose is generally three tablets in 24 hours. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and other medications. Do not exceed the prescribed dose. Take with food or milk to reduce stomach upset.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) are at increased risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Consult a doctor for dose adjustments.
Renal ImpairmentUse with caution in patients with renal impairment. Dose reduction may be necessary. Avoid use in severe renal impairment (eGFR <30 mL/min). Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid use in severe hepatic impairment. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum daily dose is generally three tablets in 24 hours, providing 300 mg diclofenac and 1500 mg paracetamol. Do not exceed this dose. Individual dosing must be determined by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of GI bleeding and liver damage.
Caffeine
Limit
May increase stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Taboran P 100 mg/500 mg Tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Stomach pain or heartburn (Common (5-10%))
Take with food. Avoid alcohol. If severe, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Rest and hydrate. Consult if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid alcohol and activities requiring alertness.
Diarrhea or constipation (Common (5-10%))
Stay hydrated. Consult if severe or persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding or ulceration (Rare (<0.1%))
Seek immediate medical attention if you notice black or tarry stools, vomiting blood, or severe abdominal pain.
Kidney problems (acute kidney injury, interstitial nephritis) (Rare (<0.1%))
Seek medical attention if you experience decreased urine output, swelling, or fatigue.
Liver damage (hepatotoxicity) (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Severe allergic reactions (anaphylaxis, angioedema) (Rare (<0.1%))
Seek emergency help if you experience rash, itching, swelling of face or throat, or difficulty breathing.
Cardiovascular events (heart attack, stroke) (Rare (<0.1%))
Seek immediate medical attention if you experience chest pain, shortness of breath, or sudden weakness.

⚠️ Rare Side Effects

Blood disorders (agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor immediately.
Pancreatitis
Seek medical attention for severe abdominal pain radiating to the back.
Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
Seek emergency care for rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
ACE inhibitors Major
Diuretics Major
Lithium Moderate
SSRIs Moderate
Cyclosporine Moderate
Tacrolimus Moderate

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., aspirin, ibuprofen)
  • Corticosteroids
  • Methotrexate
  • ACE inhibitors and angiotensin receptor blockers
  • Diuretics

⚡ Moderate Interactions

  • Lithium
  • Selective serotonin reuptake inhibitors (SSRIs)
  • Cyclosporine
  • Tacrolimus
  • Zidovudine

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver damage, especially when combined with paracetamol and diclofenac. It can also increase drowsiness and dizziness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active peptic ulcer disease or history of recurrent ulcers.","Severe heart failure, ischemic heart disease, or recent myocardial infarction.","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Take with food or milk to reduce gastrointestinal irritation.","Avoid alcohol and other NSAIDs during treatment.","Use with caution in elderly patients due to increased risk of side effects.","Monitor liver and kidney function during long-term use.","Do not exceed the recommended dose due to risk of hepatotoxicity and nephrotoxicity.","Consult your doctor if you have a history of cardiovascular disease, hypertension, or diabetes.","Do not use for more than 7 days without medical advice.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Diclofenac and paracetamol are excreted in breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose can cause severe liver damage, kidney failure, gastrointestinal bleeding, and cardiovascular events. Seek immediate medical attention. Treatment includes gastric lavage if within 1-2 hours, administration of activated charcoal, and supportive care. N-acetylcysteine is the antidote for paracetamol overdose. Monitor liver and kidney function, and provide symptomatic treatment.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than prescribed. Take each dose with a full glass of water and preferably with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver damage. Do not take other NSAIDs or paracetamol-containing products simultaneously to avoid overdose. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double the dose. If you experience any unusual symptoms, contact your doctor immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Avoid long-term use unless prescribed.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning pregnancy. NSAIDs may affect ovulation and are generally avoided in the third trimester. Paracetamol is considered relatively safe, but always consult a doctor.

🏥 Post-Surgery Considerations

This medicine may be prescribed for post-operative pain. Follow your surgeon's instructions carefully. Monitor for signs of bleeding or infection. Do not take additional painkillers without consulting your doctor.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. Your dentist may advise you to stop it temporarily.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture and ergonomics.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep to promote healing.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may worsen pain while taking this medicine. Gentle stretching and low-impact exercises are generally safe. Consult your doctor or physiotherapist for personalized advice.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce processed and fried food intake.
Stay well hydrated.
Eat plenty of fruits and vegetables.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Inform your employer if your work involves operating machinery.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects, if pain persists or worsens after 7 days, or if you develop signs of gastrointestinal bleeding, kidney problems, or liver damage. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of liver and kidney function, blood counts, and blood pressure is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor if you need to take it for more than 7 days.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve mobility.

Evidence: Well-established
Hot and cold therapy

May help reduce pain and inflammation locally.

Evidence: Limited
Acupuncture

Some evidence for chronic pain relief.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture and heat. If crossing time zones, adjust dosing times gradually to maintain pain control. Check customs regulations for carrying prescription medicines. Keep a list of your medications and allergies with you.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old retiree with post-operative knee replacement pain
Used this medicine for 10 days after surgery. Pain was well controlled, but experienced mild nausea initially. Taking it with meals helped. Blood tests showed slight elevation in liver enzymes, which normalized after stopping the medicine.
💡 Lesson: Short-term use under medical supervision is effective, but monitoring liver function is important, especially in older adults.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30-60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset and bleeding.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as it can increase the risk of side effects.

Q: Can I take it if I have high blood pressure?

A: Consult your doctor, as NSAIDs can increase blood pressure and interact with antihypertensive medicines.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Taboran P 100 mg/500 mg Tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe to take on an empty stomach.
    Fact: It should be taken with food or milk to reduce the risk of stomach irritation and bleeding.
  • Myth: More tablets mean faster pain relief.
    Fact: Taking more than the recommended dose can cause serious liver and kidney damage. Always follow the prescribed dose.
  • Myth: This medicine can be taken long-term without any monitoring.
    Fact: Long-term use requires regular monitoring of liver and kidney function and blood counts.

🔄 Alternative Options

Generic Alternatives

  • Diclofenac 100 mg + Paracetamol 500 mg tablet

Brand Alternatives

  • Dipmol SP Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Diclofenac + Paracetamol","composition":"Diclofenac 100 mg + Paracetamol 500 mg","onset":"30-60 minutes","duration":"4-6 hours","notes":"Potent anti-inflammatory and analgesic."},{"medicine":"Aceclofenac + Paracetamol","composition":"Aceclofenac 100 mg + Paracetamol 325 mg","onset":"30-60 minutes","duration":"4-6 hours","notes":"Similar efficacy, possibly better GI tolerance."},{"medicine":"Ibuprofen + Paracetamol","composition":"Ibuprofen 400 mg + Paracetamol 500 mg","onset":"30-60 minutes","duration":"4-6 hours","notes":"Commonly used for mild to moderate pain."}]

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