Swilac Oral Solution - Lactulose (3.33gm) medicine

Komfylac Syrup: Complete Guide to Uses, Dosage, and Safety

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🏭 Ind Swift Laboratories Ltd 📦 bottle of 100 ml Oral Solution 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for constipation and hepatic encephalopathy.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe diarrhea
  • Blood in stool
  • Severe abdominal pain
  • Signs of dehydration (dizziness, decreased urine)
  • Muscle weakness or irregular heartbeat
  • Allergic reaction (rash, swelling, difficulty breathing)

If experiencing severe symptoms, call emergency services immediately.

What is Swilac Oral Solution used for?

This medicine is a lactulose syrup used to treat constipation and hepatic encephalopathy. It works by drawing water into the intestines to soften stool and by reducing ammonia levels in the blood.

  • Generic Name: Lactulose (3.33gm)
  • Manufacturer: Ind Swift Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Swilac Oral Solution के बारे में (Hindi Summary)

उपयोग: यह दवा कब्ज और लिवर की बीमारी से जुड़ी हेपेटिक एन्सेफलोपैथी के इलाज के लिए इस्तेमाल की जाती है। यह आंतों में पानी खींचकर मल को नरम करती है और अमोनिया के स्तर को कम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में पेट फूलना, गैस, पेट में असुविधा और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन गंभीर दस्त, इलेक्ट्रोलाइट असंतुलन और निर्जलीकरण हो सकता है।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आपको मधुमेह है। आंतों में रुकावट या गैलेक्टोसीमिया होने पर इस दवा का सेवन न करें। पर्याप्त पानी पिएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 Swilac Oral Solution Uses & Benefits

[{"condition":"Constipation","description":"Relieves constipation by softening stools and promoting bowel movements.","evidence":"Well-established"},{"condition":"Hepatic encephalopathy","description":"Reduces blood ammonia levels in patients with liver disease.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Small intestinal bacterial overgrowth (SIBO)","description":"Sometimes used to diagnose or treat SIBO, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Constipation

Also treats: Hepatic encephalopathy

📋 Drug Information

Generic Name(s)Lactulose (3.33gm)
Brand NameSwilac Oral Solution
ManufacturerInd Swift Laboratories Ltd
Packaging / Formbottle of 100 ml Oral Solution (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C). Protect from light and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at bedtime for best results in constipation.
2
Increase fluid intake to prevent dehydration.
3
Adjust dose to produce 2-3 soft stools per day in hepatic encephalopathy.
4
Monitor for electrolyte imbalance in prolonged use.
5
Consult doctor if no bowel movement after 48 hours.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Constipation
This medicine is commonly prescribed for this.
Likely Use
✅
Confusion due to liver disease
Used for hepatic encephalopathy.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLactulose is poorly absorbed from the gastrointestinal tract. Only about 0.4-2% is absorbed unchanged.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismLactulose is metabolized by colonic bacteria into organic acids.
Half-LifeNot established from the available information.
ExcretionLactulose and its metabolites are primarily excreted in the feces. A small amount may be excreted in urine.
BioavailabilityLow, approximately 0.4-2%.
Onset of ActionThis medicine typically takes 24 to 48 hours to produce a bowel movement.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect lasts until the lactulose is fully metabolized and excreted, usually within 24 to 48 hours after a dose.

How It Works

This medicine works by osmosis. Lactulose is a synthetic disaccharide that is not absorbed in the small intestine. It passes into the colon where it is metabolized by bacteria into organic acids. These acids draw water into the colon, softening the stool and stimulating peristalsis. In hepatic encephalopathy, the acidification of the colon traps ammonia in the form of ammonium ions, which are then excreted in the stool, reducing blood ammonia levels.

Mechanism Steps

1
Ingestion and passage: Lactulose is taken orally and passes through the stomach and small intestine without being absorbed.
2
Colonic metabolism: In the colon, bacteria ferment lactulose into lactic acid, acetic acid, and other organic acids.
3
Osmotic effect: The organic acids draw water into the colon, increasing stool water content and softening the stool.
4
Peristalsis stimulation: The increased volume stimulates bowel contractions, promoting defecation.
5
Ammonia reduction: In hepatic encephalopathy, the acidic environment converts ammonia to ammonium, which is excreted.

💡 How to Take Swilac Oral Solution

Strength: Syrup containing lactulose 3.33 gm per 5 mL.

1Shake the bottle well before use.
2Measure the dose using the provided measuring cup or spoon.
3Take orally, with or without food.
4Drink a full glass of water after taking the dose.
5Follow the prescribed schedule consistently.

Dosage Information

Adult DosageThe usual adult dose for constipation is 15-30 mL (containing 10-20 g lactulose) once daily, preferably at bedtime. For hepatic encephalopathy, the dose is 30-45 mL three to four times daily, adjusted to produce 2-3 soft stools per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients, but start with a lower dose and monitor for dehydration.
Renal ImpairmentNo dose adjustment is required for renal impairment, but monitor for electrolyte imbalance.
Hepatic ImpairmentNo dose adjustment is required for hepatic impairment, but use with caution in hepatic encephalopathy as dose is titrated to effect.
Maximum Daily DoseFor constipation, maximum 60 mL per day. For hepatic encephalopathy, up to 180 mL per day under medical supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
High-fiber foods
May take together
Complements laxative effect.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Swilac Oral Solution

✅ Common Side Effects

Bloating (Common (5-10%))
Usually resolves with continued use. Consult doctor if persistent.
Gas (Common (5-10%))
May decrease over time. Avoid carbonated drinks.
Abdominal discomfort (Common (5-10%))
Take with food to reduce discomfort.
Nausea (Common (5-10%))
Take with meals. Consult doctor if severe.

🚨 Serious Side Effects

Severe diarrhea (Rare (<0.1%))
Stop the medicine and seek medical attention if diarrhea is severe or persistent.
Electrolyte imbalance (Rare (<0.1%))
Seek medical attention if you experience muscle weakness, confusion, or irregular heartbeat.
Dehydration (Rare (<0.1%))
Drink plenty of fluids. Seek medical help if you feel dizzy or have decreased urine output.

⚠️ Rare Side Effects

Allergic reaction
Seek immediate medical attention if you experience rash, itching, swelling, or difficulty breathing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other laxatives Major
Antacids Moderate
Antibiotics Moderate
Diuretics Minor

🚨 Major Interactions

  • Other laxatives

⚡ Moderate Interactions

  • Antacids
  • Antibiotics

🍷 Alcohol Interaction

Alcohol may worsen dehydration and electrolyte imbalance. Avoid excessive alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Galactosemia","Intestinal obstruction","Allergy to lactulose"]

⚠️ Warnings & Precautions

["Use with caution in diabetics due to sugar content.","Avoid in patients with galactose intolerance.","Do not use for more than 2 weeks without medical advice.","May cause dehydration if diarrhea occurs.","Consult doctor if symptoms persist."]

🤱 Lactation Safety

Lactulose is considered safe during breastfeeding as it is poorly absorbed. Consult your doctor.

💊 Overdose Management

Overdose may cause severe diarrhea, dehydration, and electrolyte imbalance. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have diabetes, as it contains sugars. Do not take this medicine if you have a bowel obstruction or galactosemia. Avoid taking other laxatives without consulting your doctor. Drink plenty of fluids to prevent dehydration. If you are pregnant or breastfeeding, consult your doctor before use. Do not exceed the recommended dose. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to dehydration and electrolyte imbalance. Monitor fluid intake and electrolytes.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy while on this medicine. It is generally considered safe but medical advice is recommended.

🏥 Post-Surgery Considerations

Consult your doctor before resuming this medicine after surgery, especially abdominal surgery.

🦷 Dental Procedures

No specific precautions. Inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Maintain a high-fiber diet.
🥗
Drink plenty of water.
😴
Exercise regularly to promote bowel movements.
💧
Establish a regular toilet routine.
🧘
Avoid delaying bowel movements.

🏋️ Exercise Considerations

No specific exercise restrictions. However, if you experience dizziness due to dehydration, avoid strenuous activities.

🥗 Diet Recommendations

Include fiber-rich foods like fruits and vegetables.
Stay well hydrated.
Avoid processed foods that can worsen constipation.

💼 Impact on Daily Work & Life

This medicine may cause bloating or gas, which can be uncomfortable but usually does not affect driving or operating machinery. If you experience dizziness, avoid driving.

🛑 When to Stop This Medicine

Stop this medicine and consult your doctor if you experience severe diarrhea, dehydration, or no improvement in symptoms after 2 weeks.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to electrolyte imbalance and dehydration. It is generally safe for extended use under medical supervision. Regular monitoring of electrolytes is recommended.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary fiber

Increasing fiber intake can help relieve constipation.

Evidence: Well-established
Probiotics

May improve gut health and regularity.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light. No time zone adjustment needed for once-daily dosing. Check customs regulations for liquid medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old man with chronic constipation
Started taking this medicine as prescribed. After 2 days, experienced relief. Noted that drinking plenty of water helped reduce bloating.
💡 Lesson: Consistency and hydration enhance the effect of this medicine.
👤 A 60-year-old woman with liver cirrhosis and hepatic encephalopathy
Prescribed this medicine to reduce ammonia levels. After a week, mental alertness improved. Required dose adjustment to achieve 2-3 soft stools daily.
💡 Lesson: Dose titration is crucial for managing hepatic encephalopathy.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually takes 24 to 48 hours to produce a bowel movement.

Q: Can I take this medicine with other laxatives?

A: Do not take with other laxatives unless prescribed by your doctor, as it may cause severe diarrhea.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Swilac Oral Solution

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is addictive.
    Fact: Lactulose is not addictive and does not cause dependency.
  • Myth: This medicine works immediately.
    Fact: It may take 24-48 hours to produce a bowel movement.

🔄 Alternative Options

Generic Alternatives

  • Lactulose solution

Brand Alternatives

  • Duphalac
  • Looz
  • Lactihep

📊 Comparison with Similar Medicines

[{"medicine":"Lactulose","class":"Osmotic laxative","onset":"24-48 hours","uses":"Constipation, hepatic encephalopathy"},{"medicine":"Polyethylene glycol","class":"Osmotic laxative","onset":"24-48 hours","uses":"Constipation"},{"medicine":"Bisacodyl","class":"Stimulant laxative","onset":"6-12 hours","uses":"Constipation"}]

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