Komfylac Syrup: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe diarrhea
- Blood in stool
- Severe abdominal pain
- Signs of dehydration (dizziness, decreased urine)
- Muscle weakness or irregular heartbeat
- Allergic reaction (rash, swelling, difficulty breathing)
If experiencing severe symptoms, call emergency services immediately.
What is lactomen syrup used for?
This medicine is a lactulose syrup used to treat constipation and hepatic encephalopathy. It works by drawing water into the intestines to soften stool and by reducing ammonia levels in the blood.
- Generic Name: Lactulose (3.33gm)
- Manufacturer: A. Menarini India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 lactomen syrup के बारे में (Hindi Summary)
उपयोग: यह दवा कब्ज और लिवर की बीमारी से जुड़ी हेपेटिक एन्सेफलोपैथी के इलाज के लिए इस्तेमाल की जाती है। यह आंतों में पानी खींचकर मल को नरम करती है और अमोनिया के स्तर को कम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में पेट फूलना, गैस, पेट में असुविधा और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन गंभीर दस्त, इलेक्ट्रोलाइट असंतुलन और निर्जलीकरण हो सकता है।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आपको मधुमेह है। आंतों में रुकावट या गैलेक्टोसीमिया होने पर इस दवा का सेवन न करें। पर्याप्त पानी पिएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 lactomen syrup Uses & Benefits
[{"condition":"Constipation","description":"Relieves constipation by softening stools and promoting bowel movements.","evidence":"Well-established"},{"condition":"Hepatic encephalopathy","description":"Reduces blood ammonia levels in patients with liver disease.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Small intestinal bacterial overgrowth (SIBO)","description":"Sometimes used to diagnose or treat SIBO, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Constipation
Also treats: Hepatic encephalopathy
📋 Drug Information
| Generic Name(s) | Lactulose (3.33gm) |
| Brand Name | lactomen syrup |
| Manufacturer | A. Menarini India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Osmotic laxatives/Purgative |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by osmosis. Lactulose is a synthetic disaccharide that is not absorbed in the small intestine. It passes into the colon where it is metabolized by bacteria into organic acids. These acids draw water into the colon, softening the stool and stimulating peristalsis. In hepatic encephalopathy, the acidification of the colon traps ammonia in the form of ammonium ions, which are then excreted in the stool, reducing blood ammonia levels.
Mechanism Steps
💡 How to Take lactomen syrup
Strength: Syrup containing lactulose 3.33 gm per 5 mL.
Dosage Information
| Adult Dosage | The usual adult dose for constipation is 15-30 mL (containing 10-20 g lactulose) once daily, preferably at bedtime. For hepatic encephalopathy, the dose is 30-45 mL three to four times daily, adjusted to produce 2-3 soft stools per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but start with a lower dose and monitor for dehydration. |
| Renal Impairment | No dose adjustment is required for renal impairment, but monitor for electrolyte imbalance. |
| Hepatic Impairment | No dose adjustment is required for hepatic impairment, but use with caution in hepatic encephalopathy as dose is titrated to effect. |
| Maximum Daily Dose | For constipation, maximum 60 mL per day. For hepatic encephalopathy, up to 180 mL per day under medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of lactomen syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other laxatives | Major | |
| Antacids | Moderate | |
| Antibiotics | Moderate | |
| Diuretics | Minor |
🚨 Major Interactions
- Other laxatives
⚡ Moderate Interactions
- Antacids
- Antibiotics
🍷 Alcohol Interaction
Alcohol may worsen dehydration and electrolyte imbalance. Avoid excessive alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Galactosemia","Intestinal obstruction","Allergy to lactulose"]
⚠️ Warnings & Precautions
["Use with caution in diabetics due to sugar content.","Avoid in patients with galactose intolerance.","Do not use for more than 2 weeks without medical advice.","May cause dehydration if diarrhea occurs.","Consult doctor if symptoms persist."]
🤱 Lactation Safety
Lactulose is considered safe during breastfeeding as it is poorly absorbed. Consult your doctor.
💊 Overdose Management
Overdose may cause severe diarrhea, dehydration, and electrolyte imbalance. Seek immediate medical attention. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have diabetes, as it contains sugars. Do not take this medicine if you have a bowel obstruction or galactosemia. Avoid taking other laxatives without consulting your doctor. Drink plenty of fluids to prevent dehydration. If you are pregnant or breastfeeding, consult your doctor before use. Do not exceed the recommended dose. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to dehydration and electrolyte imbalance. Monitor fluid intake and electrolytes.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy while on this medicine. It is generally considered safe but medical advice is recommended.
🏥 Post-Surgery Considerations
Consult your doctor before resuming this medicine after surgery, especially abdominal surgery.
🦷 Dental Procedures
No specific precautions. Inform your dentist if you are taking this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions. However, if you experience dizziness due to dehydration, avoid strenuous activities.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause bloating or gas, which can be uncomfortable but usually does not affect driving or operating machinery. If you experience dizziness, avoid driving.
🛑 When to Stop This Medicine
Stop this medicine and consult your doctor if you experience severe diarrhea, dehydration, or no improvement in symptoms after 2 weeks.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to electrolyte imbalance and dehydration. It is generally safe for extended use under medical supervision. Regular monitoring of electrolytes is recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing fiber intake can help relieve constipation.
Evidence: Well-establishedMay improve gut health and regularity.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light. No time zone adjustment needed for once-daily dosing. Check customs regulations for liquid medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually takes 24 to 48 hours to produce a bowel movement.
A: Do not take with other laxatives unless prescribed by your doctor, as it may cause severe diarrhea.
🤔 Common Patient Concerns
🔄 Substitutes for lactomen syrup
View AllAlternative brands with exact same active ingredient:
-
Swilac Oral SolutionInd Swift Laboratories Ltd ₹50.18 34.8% CHEAPER
-
lacx syrupOchoa Laboratories Ltd ₹65.00 15.5% CHEAPER
-
komfylac syrupAlembic Pharmaceuticals Ltd ₹137.50 78.8% COSTLIER
-
stulax solutionMission Research Laboratories Pvt Ltd ₹220.00 186% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is addictive.
Fact: Lactulose is not addictive and does not cause dependency. - Myth: This medicine works immediately.
Fact: It may take 24-48 hours to produce a bowel movement.
🔄 Alternative Options
Generic Alternatives
- Lactulose solution
Brand Alternatives
- Duphalac
- Looz
- Lactihep