Myorelex 500mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- High fever with muscle rigidity (possible malignant hyperthermia)
- Difficulty breathing or prolonged apnea after the procedure
- Severe allergic reaction with swelling of face, lips, or throat
- Irregular heartbeat or chest pain
- Dark brown or cola-colored urine (possible myoglobinuria)
- Severe muscle pain that does not improve
- Signs of hyperkalemia such as weakness, palpitations, or numbness
If experiencing severe symptoms, call emergency services immediately.
What is Suxim 500mg Injection used for?
This medicine is a 500 mg injection of suxamethonium, a depolarizing muscle relaxant used in hospitals to provide short-term muscle relaxation for procedures like intubation and electroconvulsive therapy. It works quickly but briefly, and must be given by a trained professional.
- Generic Name: Suxamethonium (500mg)
- Manufacturer: Samarth Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Suxim 500mg Injection के बारे में (Hindi Summary)
उपयोग: यह दवा सक्सामेथोनियम का 500 मिलीग्राम इंजेक्शन है, जिसका उपयोग अस्पताल में सर्जरी के दौरान मांसपेशियों को ढीला करने के लिए किया जाता है। यह दवा बहुत जल्दी असर करती है और इसका प्रभाव कुछ ही मिनटों तक रहता है। इसका उपयोग इंटुबैशन, इलेक्ट्रोकन्वल्सिव थेरेपी और छोटी सर्जरी में किया जाता है। यह दवा केवल प्रशिक्षित डॉक्टर द्वारा ही दी जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मांसपेशियों में फड़कन, सर्जरी के बाद मांसपेशियों में दर्द, और हृदय गति या रक्तचाप में अस्थायी वृद्धि शामिल हैं। कुछ रोगियों में पोटैशियम का स्तर बढ़ सकता है। दुर्लभ मामलों में मैलिग्नेंट हाइपरथर्मिया, एनाफिलेक्सिस, या लंबे समय तक पक्षाघात हो सकता है।
सुरक्षा सलाह: यह दवा केवल अस्पताल में प्रशिक्षित डॉक्टर द्वारा ही दी जानी चाहिए। इससे पहले कि आपको यह दवा दी जाए, अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों के बारे में बताएं, खासकर यदि आपको मैलिग्नेंट हाइपरथर्मिया, मांसपेशियों के विकार, जलन, या गुर्दे की समस्या है। इस दवा को घर पर कभी न लें।
💊 Suxim 500mg Injection Uses & Benefits
[{"condition":"Endotracheal intubation","description":"This medicine is used to provide rapid muscle relaxation to facilitate the insertion of a breathing tube during general anesthesia or emergency airway management.","evidence":"Well-established"},{"condition":"Electroconvulsive therapy (ECT)","description":"This medicine is used to prevent muscle contractions and fractures during electroconvulsive therapy by producing brief paralysis.","evidence":"Well-established"},{"condition":"Short surgical procedures","description":"This medicine provides short-lasting muscle relaxation for procedures such as endoscopy, reduction of fractures, and certain orthopedic manipulations.","evidence":"Well-established"},{"condition":"Laryngospasm","description":"This medicine can be used to relieve severe laryngospasm that does not respond to other measures.","evidence":"Limited"}]
Off-label uses: [{"condition":"Treatment of tetanus","description":"This medicine may be used off-label to control muscle spasms in tetanus, but it is not a standard first-line treatment.","evidence":"Limited"}]
Primary treatment for: Not applicable; used for procedural muscle relaxation.
📋 Drug Information
| Generic Name(s) | Suxamethonium (500mg) |
| Brand Name | Suxim 500mg Injection |
| Manufacturer | Samarth Life Sciences Pvt Ltd |
| Packaging / Form | vial of 10 ml Injection (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Parenteral (intravenous injection) |
| Storage | Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Keep in the original container. Protect from light. |
| Shelf Life | Refer to the product label for the exact shelf life. Typically, the shelf life is 24 months from the date of manufacture when stored under recommended conditions. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to nicotinic acetylcholine receptors at the motor endplate of the neuromuscular junction. Unlike non-depolarizing muscle relaxants, it acts as an agonist, causing persistent depolarization of the muscle membrane. This initial depolarization leads to muscle fasciculations, followed by flaccid paralysis because the membrane cannot repolarize while the medicine remains bound. The effect is terminated when the medicine diffuses away from the receptor and is broken down by the enzyme pseudocholinesterase in the plasma and liver. Because it is not metabolized by acetylcholinesterase at the synapse, its action is prolonged in patients with pseudocholinesterase deficiency.
Mechanism Steps
💡 How to Take Suxim 500mg Injection
Strength: Injection: 500 mg
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, patient's weight, age, and clinical status. For endotracheal intubation, a typical adult dose is 1 to 1.5 mg per kg of body weight given intravenously. For electroconvulsive therapy, a lower dose of 0.5 to 1 mg per kg may be used. The dose may be repeated as needed, but repeated doses can lead to prolonged blockade. This medicine should only be administered by trained healthcare professionals. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced pseudocholinesterase activity and decreased muscle mass, which can prolong the effect of this medicine. Doses should be individualized by a qualified clinician based on the patient's condition and response. |
| Renal Impairment | Renal impairment does not significantly affect the metabolism of this medicine, but caution is advised in patients with severe renal disease due to the risk of hyperkalemia and myoglobinuria. Dose adjustment may not be necessary, but close monitoring is recommended. |
| Hepatic Impairment | Hepatic impairment may reduce the production of pseudocholinesterase, leading to prolonged paralysis. Doses should be individualized by a qualified clinician, and close monitoring is recommended. |
| Maximum Daily Dose | Not established from the available information. The dose is determined by the clinical situation and should not exceed the minimum required to achieve the desired effect. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Suxim 500mg Injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Volatile anesthetics | Major | |
| Digitalis | Major | |
| Magnesium sulfate | Major | |
| Anticholinesterases | Major | |
| Cimetidine | Moderate | |
| Aminoglycosides | Moderate | |
| Beta-blockers | Moderate | |
| Oral contraceptives | Moderate | |
| Metoclopramide | Minor | |
| Phenothiazines | Minor |
🚨 Major Interactions
- Volatile anesthetics (e.g., halothane)
- Digitalis glycosides
- Magnesium sulfate
- Anticholinesterases (e.g., neostigmine)
- Cimetidine
⚡ Moderate Interactions
- Aminoglycoside antibiotics
- Beta-blockers
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol is not known to interact directly with this medicine, but it may increase the risk of adverse effects on the heart and central nervous system. Since this medicine is used in a controlled medical setting, alcohol consumption is not relevant during its administration.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known history of malignant hyperthermia","Skeletal muscle myopathies (e.g., Duchenne muscular dystrophy)","Severe burns (especially after the acute phase)","Spinal cord injury (after the acute phase)","Prolonged immobilization","Known pseudocholinesterase deficiency","Hypersensitivity to suxamethonium or any component of the formulation"]
⚠️ Warnings & Precautions
["This medicine should be used only by experienced healthcare professionals in a setting with facilities for intubation, artificial ventilation, and oxygen therapy.","Use with caution in patients with pre-existing hyperkalemia, digitalis toxicity, or electrolyte imbalances.","Patients with reduced pseudocholinesterase activity may experience prolonged paralysis.","This medicine may cause a transient increase in intraocular pressure; caution in patients with glaucoma.","It may cause a transient increase in intragastric pressure; caution in patients with full stomach.","Repeated doses may lead to tachyphylaxis or prolonged blockade.","Use with caution in patients with cardiovascular disease, especially those with arrhythmias."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a nursing woman. Since it is used in a hospital setting for short procedures, the exposure to the infant is likely minimal.
💊 Overdose Management
Overdose of this medicine results in prolonged neuromuscular blockade, leading to apnea and paralysis. Management includes immediate mechanical ventilation and supportive care until the medicine is metabolized. There is no specific antidote. If pseudocholinesterase deficiency is suspected, fresh frozen plasma or purified pseudocholinesterase may be considered. Continuous monitoring of vital signs and neuromuscular function is essential.
⏰ Missed Dose
This medicine is administered by a healthcare professional in a controlled setting. Missed doses are not applicable. If you miss an appointment for a procedure requiring this medicine, contact your healthcare provider to reschedule.
Additional Safety Advice
This medicine must only be administered by a qualified anesthesiologist or trained healthcare professional in a hospital or surgical setting. Before receiving this medicine, inform your doctor about all your medical conditions, especially any history of malignant hyperthermia, muscle disorders, burns, spinal cord injury, or kidney problems. Also, tell your doctor about all medications you are taking, including over-the-counter drugs and herbal supplements, as some may interact with this medicine. Do not attempt to take this medicine at home or outside a medical facility. After receiving this medicine, you will be closely monitored for any adverse reactions. If you experience muscle pain, difficulty breathing, or any unusual symptoms after the procedure, report them to your healthcare provider immediately. Always ensure that your medical team is aware of any allergies you have.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced pseudocholinesterase activity and decreased muscle mass, which can prolong the effect of this medicine. Doses should be individualized, and close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before receiving this medicine. It is not known if this medicine affects fertility.
🏥 Post-Surgery Considerations
After surgery, you will be monitored in the recovery room until the effects of this medicine wear off. You may experience muscle pain or weakness. Follow your doctor's instructions for post-operative care.
🦷 Dental Procedures
This medicine may be used during dental procedures that require general anesthesia. Inform your dentist if you have any history of malignant hyperthermia or muscle disorders.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting for at least 24 hours after receiving this medicine, as you may experience muscle weakness or pain. Gradually resume activities as tolerated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
You should not drive or operate heavy machinery for at least 24 hours after receiving this medicine, as it may cause drowsiness or muscle weakness. Plan to have someone drive you home after the procedure.
🛑 When to Stop This Medicine
This medicine is given as a single dose or repeated doses during a procedure. It is stopped by the healthcare professional once the procedure is complete. Do not attempt to stop or adjust the dose yourself.
📅 Long-Term Use Effects
This medicine is used for short-term muscle relaxation and is not intended for long-term use. There are no known long-term effects from a single administration. However, repeated use may lead to prolonged paralysis or tachyphylaxis. Monitoring is required during administration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Medicines like rocuronium or vecuronium can be used as alternatives, but they have a longer duration of action.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for a procedure, inform your doctor about any recent vaccinations.
📦 Storage Guide
✅ DO
Store in a refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to another container
✅ DO
Protect from light
❌ DON'T
Do not use if the solution is discolored or contains particles
✈️ Traveling with This Medicine
This medicine is administered only in a hospital setting and is not for personal travel. If you are traveling to a location where you may need medical procedures, carry a copy of your prescription and medical records. Store the medicine as directed by the manufacturer. Do not pack it in checked luggage if you are a healthcare professional transporting it. Always declare any medical items to customs as required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 to 60 seconds after intravenous injection.
A: The muscle relaxation typically lasts 5 to 10 minutes, but it may be longer in some patients.
A: You may feel a brief burning sensation at the injection site, but you will be under anesthesia or sedation.
A: This medicine should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for Suxim 500mg Injection
View AllAlternative brands with exact same active ingredient:
-
myorelex 500mg injectionNeon Laboratories Ltd ₹55.08 39.9% COSTLIER
-
Suxalin 500mg InjectionCelon Laboratories Ltd ₹66.60 69.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used at home for muscle pain.
Fact: This medicine is a hospital-only injectable muscle relaxant and must never be used outside a medical facility. - Myth: This medicine is a painkiller.
Fact: This medicine does not relieve pain; it only causes muscle paralysis. - Myth: This medicine is safe for everyone.
Fact: It is contraindicated in certain conditions like malignant hyperthermia and muscle disorders.
🔄 Alternative Options
Generic Alternatives
- Suxamethonium chloride
Brand Alternatives
- Myorelex 500mg injection