Adenosine 3mg Injection: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe chest pain or tightness that does not resolve quickly
- Difficulty breathing or wheezing
- Fainting or loss of consciousness
- Prolonged pause in heartbeat or severe dizziness
- Signs of allergic reaction such as rash, swelling of face or throat
- Seizures
- Severe headache with visual changes
If experiencing severe symptoms, call emergency services immediately.
What is adenosine 3mg injection used for?
Adenosine 3mg injection is a rapid-acting intravenous medicine used to treat paroxysmal supraventricular tachycardia (PSVT) by briefly blocking electrical signals in the AV node, restoring normal heart rhythm. It is given only by healthcare professionals in a monitored setting.
- Generic Name: Adenosine
- Manufacturer: Samarth Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 adenosine 3mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा एडेनोसिन का इंजेक्शन है, जिसका उपयोग दिल की धड़कन की कुछ खास समस्याओं, जैसे पैरॉक्सिस्मल सुप्रावेंट्रिकुलर टैकीकार्डिया (PSVT), के इलाज के लिए किया जाता है। यह दिल की धड़कन को सामान्य करने में मदद करती है। यह दवा केवल अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा नस में इंजेक्शन के रूप में दी जाती है। इसे घर पर नहीं लिया जा सकता। यह दवा दिल की धड़कन को नियंत्रित करने वाले विद्युत संकेतों को अस्थायी रूप से धीमा करके काम करती है। यह दवा उन लोगों के लिए नहीं है जिन्हें दिल की धड़कन में गंभीर रुकावट, सिक साइनस सिंड्रोम, या अस्थमा है। इस दवा का उपयोग करने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चेहरे पर गर्मी लगना, सीने में दबाव या जकड़न, सांस लेने में तकलीफ, और सिरदर्द शामिल हैं। ये आमतौर पर कुछ सेकंड से लेकर एक मिनट के भीतर ठीक हो जाते हैं। कुछ लोगों को चक्कर आना, मतली, या मुंह में धातु जैसा स्वाद भी महसूस हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें दिल की धड़कन का लंबे समय तक रुकना, गंभीर ब्रैडीकार्डिया, या अस्थमा के दौरे शामिल हो सकते हैं। यह दवा केवल डॉक्टर की निगरानी में दी जाती है, इसलिए किसी भी गंभीर प्रभाव का तुरंत इलाज किया जा सकता है।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा दी जाती है। इसे घर पर खुद से न लें। इस दवा को लेने से पहले अपने डॉक्टर को अस्थमा, सीओपीडी, दिल की धड़कन में रुकावट, सिक साइनस सिंड्रोम, निम्न रक्तचाप, या दौरे की समस्या के बारे में बताएं। साथ ही, अपनी सभी दवाओं की जानकारी दें, खासकर डिपाइरिडामोल, कार्बामाजेपिन, या थियोफिलिन। इंजेक्शन के बाद कुछ समय तक निगरानी की जाएगी। जब तक आप पूरी तरह ठीक महसूस न करें और डॉक्टर अनुमति न दें, तब तक वाहन न चलाएं या मशीनरी का संचालन न करें।
💊 adenosine 3mg injection Uses & Benefits
[{"condition":"Paroxysmal supraventricular tachycardia (PSVT)","description":"This medicine is used to rapidly convert PSVT to normal sinus rhythm by temporarily blocking conduction through the AV node.","evidence":"Well-established"},{"condition":"AV nodal reentrant tachycardia (AVNRT)","description":"It terminates AVNRT by interrupting the reentrant circuit within the AV node.","evidence":"Well-established"},{"condition":"AV reentrant tachycardia (AVRT) associated with Wolff-Parkinson-White syndrome","description":"It can terminate AVRT by blocking the antegrade conduction through the AV node, breaking the circuit.","evidence":"Well-established"},{"condition":"Diagnostic use during myocardial perfusion stress testing","description":"Adenosine is used as a pharmacological stress agent to produce coronary vasodilation in patients who cannot exercise adequately.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Unstable angina or coronary spasm provocation testing","description":"Rarely used off-label to provoke coronary spasm during angiography in specialized centers.","evidence":"Limited"},{"condition":"Pulmonary hypertension testing","description":"Sometimes used off-label during right heart catheterization to assess pulmonary vasoreactivity.","evidence":"Limited"}]
Primary treatment for: Paroxysmal supraventricular tachycardia (PSVT)
Also treats: AV nodal reentrant tachycardia, AV reentrant tachycardia associated with Wolff-Parkinson-White syndrome
📋 Drug Information
| Generic Name(s) | Adenosine |
| Brand Name | Adenoscan |
| Manufacturer | Samarth Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Miscellaneous agents- anti arrhythmic |
| Route of Administration | Intravenous |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Do not freeze. Keep in the original container until use. |
| Shelf Life | Refer to the product label for the expiration date. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Adenosine binds to A1 receptors on cardiac pacemaker cells and atrial myocytes, activating an inward rectifier potassium current (IKAdo) and inhibiting the slow inward calcium current. This shortens the action potential duration and hyperpolarizes the cell membrane, leading to reduced automaticity and slowed conduction, especially through the AV node. The result is a transient block of the reentrant circuit that causes supraventricular tachycardia.
Mechanism Steps
💡 How to Take adenosine 3mg injection
Strength: Adenosine 3 mg/mL injection, available in 2 mL vials (total 6 mg) and other presentations.
Dosage Information
| Adult Dosage | The usual adult dose for paroxysmal supraventricular tachycardia is an initial rapid intravenous bolus of 6 mg given over 1 to 2 seconds. If the arrhythmia does not resolve within 1 to 2 minutes, a second dose of 12 mg may be given. Doses may be repeated once more if needed. For diagnostic stress testing, the dose is individualized based on the protocol. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and clinical response. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but they may be more sensitive to the effects of adenosine. Use with caution and monitor closely. |
| Renal Impairment | No dose adjustment is required for renal impairment because adenosine is not dependent on renal excretion for its action. |
| Hepatic Impairment | No dose adjustment is required for hepatic impairment because adenosine is not metabolized by the liver. |
| Maximum Daily Dose | The maximum recommended single dose is 12 mg, and a maximum of three doses may be given in a single setting. The total daily dose should not exceed 36 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of adenosine 3mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Dipyridamole | Major | |
| Carbamazepine | Major | |
| Theophylline | Major | |
| Beta-blockers | Moderate | |
| Calcium channel blockers | Moderate | |
| Digoxin | Moderate | |
| Caffeine | Minor | |
| Nicotine | Minor |
🚨 Major Interactions
- Dipyridamole
- Carbamazepine
- Theophylline and aminophylline
⚡ Moderate Interactions
- Beta-blockers
- Calcium channel blockers
- Digoxin
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness and low blood pressure. Avoid alcohol before and after receiving this medicine until you are fully recovered.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Second- or third-degree AV block (except in patients with a functioning artificial pacemaker)","Sick sinus syndrome (except in patients with a functioning artificial pacemaker)","Known hypersensitivity to adenosine","Atrial fibrillation or atrial flutter (not effective and may increase ventricular rate)","Ventricular tachycardia (not effective)"]
⚠️ Warnings & Precautions
["This medicine should be administered only by healthcare professionals in a setting with continuous cardiac monitoring and resuscitation equipment.","Use with caution in patients with asthma or COPD due to risk of bronchospasm.","Use with caution in patients with low blood pressure or autonomic dysfunction.","Avoid in patients with known adenosine deaminase deficiency.","Theophylline and caffeine may antagonize the effects of adenosine.","Dipyridamole may potentiate the effects of adenosine; avoid concomitant use."]
🤱 Lactation Safety
It is not known whether adenosine is excreted in human breast milk. Because of its very short half-life, it is unlikely to reach significant levels in milk. Consult your doctor before breastfeeding after receiving this medicine.
💊 Overdose Management
Overdose with adenosine is unlikely because it is given in controlled settings and has a very short half-life. If excessive bradycardia or prolonged asystole occurs, treatment is supportive and may include atropine, aminophylline, or temporary pacing. Because adenosine is rapidly metabolized, effects are short-lived.
⏰ Missed Dose
This medicine is given as a single dose in a monitored setting. Missed doses are not applicable.
Additional Safety Advice
This medicine is for hospital or clinic use only and must be given by a healthcare professional. Do not attempt to administer it at home. Before receiving this medicine, tell your doctor if you have asthma, COPD, heart block, sick sinus syndrome, low blood pressure, or a history of seizures. Also inform them about any medicines you take, especially those that affect heart rhythm or adenosine levels, such as dipyridamole, carbamazepine, or theophylline. After the injection, you will be monitored for a short period. Do not drive or operate machinery immediately after receiving this medicine until you feel completely normal and your doctor says it is safe. If you experience severe chest pain, difficulty breathing, or fainting after the injection, seek emergency help right away.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of adenosine, especially bradycardia and hypotension. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy and have a history of PSVT, discuss with your doctor about the safest treatment options. Adenosine is generally considered safe for acute use during pregnancy, but long-term management may need adjustment.
🏥 Post-Surgery Considerations
If you have recently had surgery, inform your surgeon and anesthesiologist about your history of arrhythmias and any use of adenosine. Adenosine can be used during surgery if needed, but monitoring is essential.
🦷 Dental Procedures
Inform your dentist if you have a history of PSVT or have received adenosine. Some dental procedures may require precautions, especially if you are taking other heart medications.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
After receiving adenosine, avoid strenuous exercise or heavy lifting for the rest of the day. Gradually resume normal activities as you feel better and as advised by your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
You should not drive or operate heavy machinery immediately after receiving adenosine. It is best to have someone else drive you home. You can usually resume normal activities the next day unless your doctor advises otherwise.
🛑 When to Stop This Medicine
Adenosine is given as a single dose in a controlled setting, so there is no ongoing use to stop. If you experience any unusual symptoms after the injection, report them to your doctor immediately.
📅 Long-Term Use Effects
Adenosine is not used long-term. It is a short-acting medicine given for acute episodes. There are no known long-term effects from a single dose. If you have recurrent arrhythmias, your doctor may prescribe other long-term medications or procedures.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Techniques like bearing down or coughing can sometimes terminate PSVT without medicine.
Evidence: Well-establishedCalcium channel blockers can be used to terminate PSVT if adenosine is contraindicated.
Evidence: Well-establishedA procedure to destroy the abnormal electrical pathway causing PSVT, offering a long-term cure.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between adenosine and vaccines. However, if you are scheduled for a procedure requiring adenosine, inform your doctor about any recent vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not use if the solution is discolored or contains particles
✈️ Traveling with This Medicine
This medicine is administered only in a hospital or clinic setting, so travel advice is not applicable for self-administration. If you are traveling after receiving this medicine, ensure you are fully recovered and cleared by your doctor before driving or flying. Carry a copy of your prescription and medical records if you have a history of arrhythmias.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Adenosine works within seconds after injection. Its effects last less than a minute.
A: You may feel a brief flushing, chest pressure, or shortness of breath. These effects usually pass quickly.
A: Adenosine can cause bronchospasm, so it should be used with caution in patients with asthma. Inform your doctor if you have asthma.
A: Adenosine is generally considered safe for use during pregnancy when clinically indicated, but consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for adenosine 3mg injection
View AllAlternative brands with exact same active ingredient:
-
adenoject 3mg injectionSun Pharmaceutical Industries Ltd ₹173.77 16.5% CHEAPER
-
adenocor 3mg injectionSanofi India Ltd ₹187.61 9.8% CHEAPER
-
adnet 3mg injectionSPM Drugs Pvt Ltd ₹275.00 32.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Adenosine can be used to treat all types of fast heart rates.
Fact: Adenosine is only effective for specific supraventricular tachycardias. It is not effective for atrial fibrillation, atrial flutter, or ventricular tachycardia. - Myth: Adenosine is a sedative.
Fact: Adenosine is not a sedative. It is an antiarrhythmic that acts on the heart's electrical system. - Myth: You can take adenosine at home for palpitations.
Fact: Adenosine must be given intravenously by a healthcare professional in a monitored setting because it can cause serious heart rhythm disturbances.
🔄 Alternative Options
Generic Alternatives
- Adenosine injection
Brand Alternatives
- Adenosine 3mg injection