Sunflo TZ Tablet: Comprehensive Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, difficulty breathing.
- Sudden severe joint pain, swelling, or inability to move a limb (possible tendon rupture).
- Seizures or severe confusion.
- Bloody diarrhea or severe abdominal pain.
- Yellowing of eyes or skin, dark urine (signs of liver problems).
- Irregular heartbeat or fainting.
- Severe skin rash with blisters or peeling.
If experiencing severe symptoms, call emergency services immediately.
What is sunflo tz tablet used for?
This medicine is a combination antibiotic containing ofloxacin and tinidazole. It is used to treat mixed bacterial and protozoal infections, especially those causing diarrhea, amoebiasis, and giardiasis. It works by killing bacteria and parasites. It must be taken exactly as prescribed, and alcohol must be avoided during and for 72 hours after treatment.
- Generic Name: Ofloxacin (NA) + Tinidazole (NA)
- Manufacturer: Alembic Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sunflo tz tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ओफ्लोक्सासिन और टिनिडाजोल का संयोजन है, जिसका उपयोग विभिन्न जीवाणु और परजीवी संक्रमणों के इलाज के लिए किया जाता है। यह मुख्य रूप से दस्त, अमीबियासिस, जियार्डियासिस, पेल्विक इंफ्लेमेटरी डिजीज और दांतों के संक्रमण में प्रभावी है। यह दवा कीटाणुओं और परजीवियों को मारकर काम करती है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स करना जरूरी है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट में असहजता, मुंह में धातु जैसा स्वाद, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें एलर्जी, टेंडन टूटना, दौरे, और त्वचा पर गंभीर प्रतिक्रियाएं शामिल हो सकती हैं। शराब के साथ इस दवा का सेवन करने पर गंभीर प्रतिक्रिया हो सकती है।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कोर्स पूरा करें, बीच में न छोड़ें। शराब का सेवन बिल्कुल न करें, क्योंकि इससे गंभीर प्रतिक्रिया हो सकती है। दवा लेते समय पर्याप्त पानी पिएं। चक्कर आने पर वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। धूप से बचें और सनस्क्रीन का उपयोग करें।
💊 sunflo tz tablet Uses & Benefits
[{"condition":"Infectious diarrhea","description":"Used to treat diarrhea caused by mixed bacterial and protozoal pathogens, including Shigella, Salmonella, and Entamoeba histolytica.","evidence":"Well-established"},{"condition":"Amoebiasis","description":"Effective against intestinal and hepatic amoebiasis caused by Entamoeba histolytica.","evidence":"Well-established"},{"condition":"Giardiasis","description":"Treats giardiasis, a parasitic infection of the small intestine causing diarrhea and malabsorption.","evidence":"Well-established"},{"condition":"Pelvic inflammatory disease","description":"Used as part of combination therapy for pelvic inflammatory disease caused by mixed aerobic and anaerobic bacteria.","evidence":"Moderate"},{"condition":"Dental infections","description":"Prescribed for dental abscesses and periodontal infections where anaerobic bacteria are involved.","evidence":"Moderate"},{"condition":"Bacterial vaginosis","description":"Sometimes used to treat bacterial vaginosis, though other agents are more commonly preferred.","evidence":"Limited"}]
Off-label uses: [{"condition":"Traveler's diarrhea prophylaxis","description":"Occasionally prescribed off-label to prevent traveler's diarrhea in high-risk situations, but not routinely recommended due to resistance and side effects.","evidence":"Limited"},{"condition":"Helicobacter pylori eradication","description":"Sometimes included in quadruple therapy regimens for H. pylori, though not a first-line choice.","evidence":"Limited"}]
Primary treatment for: Mixed bacterial and protozoal infections
Also treats: Infectious diarrhea, Amoebiasis, Giardiasis, Pelvic inflammatory disease, Dental infections
📋 Drug Information
| Generic Name(s) | Ofloxacin (NA) + Tinidazole (NA) |
| Brand Name | sunflo tz tablet |
| Manufacturer | Alembic Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antimicrobial agents with complementary mechanisms. Ofloxacin is a fluoroquinolone that inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. This leads to double-strand DNA breaks and bacterial cell death. Tinidazole is a nitroimidazole prodrug that enters anaerobic organisms and is reduced by ferredoxin-like electron transport proteins. The reduced intermediates bind to DNA, causing strand breakage and inhibiting nucleic acid synthesis. This dual action covers a broad spectrum of aerobic and anaerobic bacteria as well as protozoa like Giardia and Entamoeba.
Mechanism Steps
💡 How to Take sunflo tz tablet
Strength: Ofloxacin 200 mg + Tinidazole 600 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily, depending on the infection being treated. The exact dose and duration must be individualized by a qualified clinician based on the indication, severity of infection, age, weight, renal and hepatic function. Do not self-adjust the dose. Always complete the full course as prescribed. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Ofloxacin clearance decreases with age, increasing the risk of side effects. Monitor renal function and adjust dose as needed. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For creatinine clearance below 50 mL/min, the dose of ofloxacin should be reduced or the dosing interval extended. Consult a clinician for specific guidance. |
| Hepatic Impairment | No specific dose adjustment is established for mild to moderate hepatic impairment. In severe liver disease, use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum daily dose should not exceed the prescribed amount. Typically, ofloxacin 400 mg twice daily is the maximum, but this must be confirmed by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sunflo tz tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Amiodarone | Major | |
| Antacids | Moderate | |
| Theophylline | Moderate | |
| NSAIDs | Moderate | |
| Corticosteroids | Moderate | |
| Oral hypoglycemics | Moderate | |
| Caffeine | Minor | |
| Probenecid | Minor |
🚨 Major Interactions
- Warfarin
- Alcohol
- QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)
- Antacids, sucralfate, iron, zinc, calcium
⚡ Moderate Interactions
- Theophylline
- NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Oral hypoglycemics
🍷 Alcohol Interaction
Alcohol must be strictly avoided while taking this medicine and for at least 72 hours after the last dose. Tinidazole can cause a disulfiram-like reaction characterized by severe nausea, vomiting, flushing, headache, and palpitations. This reaction can be dangerous and requires immediate medical attention if it occurs.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ofloxacin, tinidazole, or other fluoroquinolones or nitroimidazoles.","History of tendon disorders associated with fluoroquinolone use.","Myasthenia gravis (may worsen muscle weakness).","Severe renal impairment without dose adjustment.","Pregnancy and breastfeeding unless clearly necessary.","Children and adolescents under 18 years (fluoroquinolones may affect cartilage development).","Alcohol consumption during and for 72 hours after therapy."]
⚠️ Warnings & Precautions
["Fluoroquinolones can cause tendon inflammation and rupture, especially in older adults, those on corticosteroids, and organ transplant recipients. Stop at first sign of tendon pain.","May cause peripheral neuropathy. Discontinue if symptoms occur.","Can exacerbate myasthenia gravis. Avoid in these patients.","May cause CNS effects including seizures, confusion, and hallucinations. Use caution in patients with epilepsy.","Avoid excessive sun exposure due to photosensitivity risk.","May cause hypoglycemia in diabetic patients. Monitor blood sugar.","Do not use for viral infections. Inappropriate use promotes resistance.","Complete the full course as prescribed to prevent relapse and resistance."]
🤱 Lactation Safety
Ofloxacin and tinidazole are excreted in breast milk. Breastfeeding is not recommended while taking this medicine. If treatment is essential, consult your doctor about temporarily stopping breastfeeding or using an alternative.
💊 Overdose Management
Overdose may cause nausea, vomiting, dizziness, and seizures. There is no specific antidote. Treatment is supportive and symptomatic. Maintain hydration and monitor vital signs. In case of accidental overdose, contact a poison control center or emergency department immediately.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Swallow the tablet whole with a full glass of water. You may take it with food to reduce stomach upset. Avoid all alcohol during treatment and for at least 72 hours after the last dose, as it can cause a severe reaction. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have kidney or liver problems, epilepsy, myasthenia gravis, or tendon disorders. Avoid excessive sunlight and use sunscreen, as this medicine can make your skin more sensitive to UV rays. If you are pregnant, planning pregnancy, or breastfeeding, tell your doctor before taking this medicine. Do not share this medicine with anyone else. Keep it out of reach of children. Store at room temperature away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, kidney impairment, and CNS effects. Dose adjustment based on renal function is often necessary. Monitor closely for side effects.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It is generally avoided during pregnancy unless the benefits outweigh the risks. Use effective contraception during treatment.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to prevent or treat infection. Follow your surgeon's instructions carefully. Inform your surgeon if you have any allergies or kidney problems.
🦷 Dental Procedures
This medicine may be prescribed for dental infections. Inform your dentist if you are taking this medicine before any dental procedure. It may interact with other medications used during dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon injury. If you experience joint pain, stop exercising and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take rest if you feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Complete the full prescribed course. If you experience serious side effects such as tendon pain, severe allergic reaction, or seizures, stop immediately and seek medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically prescribed for a chronic infection. Prolonged use can increase the risk of antibiotic resistance, fungal overgrowth, and rare side effects such as peripheral neuropathy or tendon damage. Regular monitoring of kidney and liver function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Essential for managing dehydration caused by diarrhea.
Evidence: Well-establishedMay help restore gut flora and reduce antibiotic-associated diarrhea.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions known with this medicine. However, antibiotics may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Consult your doctor for timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from moisture and direct sunlight. If crossing time zones, continue taking the medicine at the same intervals as prescribed; consult your doctor for specific advice. Avoid alcohol during travel. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.
A: Yes, taking it with food helps reduce stomach upset.
A: Avoid alcohol completely, and avoid taking antacids, iron, or calcium supplements within 2 hours of this medicine.
A: Consult your doctor. It is generally avoided during pregnancy unless clearly necessary.
A: No, you must complete the full course to prevent relapse and resistance.
🤔 Common Patient Concerns
🔄 Substitutes for sunflo tz tablet
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of diarrhea.
Fact: It only works for specific bacterial and protozoal infections. It is not effective for viral diarrhea or diarrhea caused by other conditions. - Myth: You can stop taking it once you feel better.
Fact: You must complete the full course to prevent relapse and antibiotic resistance. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol can cause a severe disulfiram-like reaction with tinidazole. Avoid completely during and for 72 hours after treatment. - Myth: This medicine is safe for children.
Fact: Fluoroquinolones are generally not recommended for children due to potential effects on cartilage development. Consult a pediatrician.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin + Tinidazole combination tablets from other manufacturers
Brand Alternatives
- Ofloxacin + Tinidazole tablets (various brands)