Sucrafil DS Oral Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or cramping
- Chest pain, palpitations, or fainting
- Difficulty breathing or swelling of face, lips, or throat
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or swelling in legs
- Uncontrollable muscle spasms or tremors
If experiencing severe symptoms, call emergency services immediately.
What is sucrafil ds oral suspension used for?
This medicine is a combination of sucralfate and domperidone used to treat acid reflux, gastritis, and ulcers. It works by protecting the stomach lining and improving gut motility.
- Generic Name: Sucralfate (500mg/5ml) + Domperidone (5mg/5ml)
- Manufacturer: Fourrts India Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sucrafil ds oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा सूक्राल्फेट और डोम्पेरिडोन का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, गैस्ट्रिटिस और अल्सर के इलाज के लिए किया जाता है। यह पेट की परत की रक्षा करती है और पेट खाली होने में मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुँह सूखना, कब्ज, दस्त, सिरदर्द और पेट में परेशानी शामिल हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी प्रतिक्रिया या मांसपेशियों में अकड़न हो सकती है।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। खाली पेट लें, भोजन से 30-60 मिनट पहले। एंटासिड के साथ न लें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 sucrafil ds oral suspension Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Helps reduce acid reflux symptoms by protecting the esophageal lining and improving gastric emptying.","evidence":"Well-established"},{"condition":"Gastritis","description":"Soothes inflamed stomach lining and promotes healing.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Forms a protective barrier over ulcers to aid healing and reduce pain.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Relieves symptoms like bloating, early satiety, and upper abdominal discomfort.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Nausea and vomiting of various causes","description":"Domperidone component may help reduce nausea, but not a primary indication.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Gastritis, Peptic ulcer disease, Functional dyspepsia
📋 Drug Information
| Generic Name(s) | Sucralfate (500mg/5ml) + Domperidone (5mg/5ml) |
| Brand Name | sucrafil ds oral suspension |
| Manufacturer | Fourrts India Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Sucralfate works by forming a complex with proteins in the ulcer base, creating a protective barrier that shields the damaged tissue from acid, pepsin, and bile. It also inhibits pepsin activity and binds bile acids. Domperidone is a peripheral dopamine D2 receptor antagonist that enhances gastric motility and accelerates gastric emptying without crossing the blood-brain barrier significantly, thus reducing nausea and vomiting.
Mechanism Steps
💡 How to Take sucrafil ds oral suspension
Strength: Each 5 mL of oral suspension contains sucralfate 500 mg and domperidone 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 10 mL of the suspension (containing sucralfate 500 mg and domperidone 5 mg per 5 mL) taken three to four times daily, preferably on an empty stomach, 30 minutes to 1 hour before meals and at bedtime. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of domperidone, especially cardiac effects. Use with caution and adjust dose as needed under medical supervision. |
| Renal Impairment | Sucralfate may accumulate in renal impairment. Use with caution and monitor renal function. Dose adjustment may be necessary. |
| Hepatic Impairment | Domperidone is metabolized in the liver; use with caution in hepatic impairment. Dose adjustment may be required. |
| Maximum Daily Dose | The maximum recommended daily dose of domperidone is 30 mg (which corresponds to 30 mL of this suspension per day). Do not exceed this dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sucrafil ds oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Clarithromycin | Major | |
| Amiodarone | Major | |
| Antacids | Moderate | |
| Warfarin | Moderate | |
| Digoxin | Minor |
🚨 Major Interactions
- Ketoconazole, itraconazole, clarithromycin, ritonavir
- QT-prolonging drugs (e.g., amiodarone, sotalol)
⚡ Moderate Interactions
- Antacids
- Warfarin
🍷 Alcohol Interaction
Alcohol may increase stomach irritation and worsen the condition being treated. Avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to sucralfate or domperidone","Gastrointestinal obstruction, perforation, or bleeding","Prolactin-releasing pituitary tumor (prolactinoma)","Severe renal impairment (for sucralfate)","Concomitant use with strong CYP3A4 inhibitors or QT-prolonging drugs"]
⚠️ Warnings & Precautions
["Use with caution in elderly patients due to increased risk of side effects.","Avoid in patients with pre-existing QT prolongation or cardiac disease.","Sucralfate may reduce absorption of other drugs; separate administration by 2 hours.","Domperidone should be used at the lowest effective dose for the shortest duration.","Monitor renal function in patients with kidney disease."]
🤱 Lactation Safety
Domperidone may pass into breast milk. Sucralfate is minimally absorbed. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause drowsiness, extrapyramidal symptoms, and QT prolongation. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be considered if within 1 hour of ingestion.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Shake the bottle well before each use to ensure the suspension is mixed properly. Measure the dose with the provided measuring cup or spoon, not with a regular household spoon. Avoid taking this medicine within two hours of antacids or other medications, as sucralfate can reduce their absorption. Do not use this medicine for longer than recommended without medical supervision. Inform your doctor if you have kidney or liver disease, heart problems, or if you are pregnant or breastfeeding. Avoid alcohol while taking this medicine as it may worsen stomach irritation. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to side effects like cardiac arrhythmias and extrapyramidal symptoms. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor. The safety of this combination in pregnancy is not well established. Alternative treatments may be considered.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, especially if you have had gastrointestinal surgery.
🦷 Dental Procedures
No specific precautions. Inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid vigorous exercise immediately after meals, as it may worsen reflux. Light activities like walking are beneficial.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery if you feel affected. Otherwise, it should not significantly impact your daily activities.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of domperidone may increase the risk of cardiac side effects and hyperprolactinemia. Sucralfate may cause aluminum accumulation in patients with renal impairment. Regular monitoring is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Avoiding trigger foods can reduce symptoms.
Evidence: Well-establishedReduces abdominal pressure and reflux.
Evidence: Well-establishedStress can worsen digestive symptoms.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. Continue routine vaccinations as advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually to maintain consistent intervals. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling relief within 30-60 minutes, but full effects may take a few days of regular use.
A: Some medicines may interact. Always inform your doctor about all medicines you are taking.
A: Consult your doctor. The safety profile in pregnancy is not well established.
🤔 Common Patient Concerns
🔄 Substitutes for sucrafil ds oral suspension
View AllAlternative brands with exact same active ingredient:
-
domsafe 5mg/5ml/500mg/5ml suspensionEskag Pharma Pvt Ltd ₹107.00 16.4% CHEAPER
-
pepsigard-p suspensionSAF Fermion Ltd ₹181.50 41.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken with antacids.
Fact: Antacids can reduce the effectiveness of sucralfate. Separate doses by at least 2 hours. - Myth: It is safe to take this medicine for long periods without supervision.
Fact: Long-term use should be monitored by a doctor due to potential side effects.
🔄 Alternative Options
Generic Alternatives
- Sucralfate + Domperidone oral suspension