Spirodin Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
- Irregular or rapid heartbeat
- Seizures
- Severe nausea and vomiting
- Chest pain
- Loss of consciousness
If experiencing severe symptoms, call emergency services immediately.
What is spirodin injection used for?
This medicine is a bronchodilator injection containing doxofylline, used to treat asthma and COPD by relaxing airway muscles.
- Generic Name: Doxofylline (10mg/ml)
- Manufacturer: Koye Pharmaceuticals Pvt ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 spirodin injection के बारे में (Hindi Summary)
उपयोग: यह दवा डॉक्सोफाइलिन इंजेक्शन है, जिसका उपयोग अस्थमा और सीओपीडी जैसी श्वसन संबंधी समस्याओं के इलाज में किया जाता है। यह श्वास नलियों की मांसपेशियों को आराम देकर सांस लेने में आसानी प्रदान करती है। यह केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा ही दी जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, सिरदर्द और बेचैनी शामिल हैं। गंभीर दुष्प्रभावों में अनियमित दिल की धड़कन और दौरे पड़ सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल स्वास्थ्यकर्मी द्वारा दी जानी चाहिए। यदि आपको हृदय, यकृत या गुर्दे की बीमारी है, या आप गर्भवती या स्तनपान करा रही हैं, तो अपने डॉक्टर को बताएं। इस दवा के साथ शराब का सेवन न करें।
💊 spirodin injection Uses & Benefits
[{"condition":"Bronchial asthma","description":"Used to relieve bronchospasm and improve breathing in acute asthma exacerbations.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Helps to relax airways and reduce breathlessness in COPD patients.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Bronchial asthma
Also treats: Chronic obstructive pulmonary disease (COPD)
📋 Drug Information
| Generic Name(s) | Doxofylline (10mg/ml) |
| Brand Name | spirodin injection |
| Manufacturer | Koye Pharmaceuticals Pvt ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Theophylline & its derivatives |
| Route of Administration | Parenteral |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze. |
| Shelf Life | Not established from the available information. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Doxofylline inhibits phosphodiesterase enzymes, leading to increased cyclic AMP levels in airway smooth muscle cells. This results in relaxation of bronchial smooth muscle and bronchodilation. It also has anti-inflammatory effects and may improve respiratory muscle contractility.
Mechanism Steps
💡 How to Take spirodin injection
Strength: Injection, 10 mg/ml
Dosage Information
| Adult Dosage | The dosage of this medicine is determined by the healthcare provider based on the patient's condition, age, weight, and renal and hepatic function. It is typically administered intravenously or intramuscularly. Dose must be individualized by a qualified clinician. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal and hepatic function. Use with caution. |
| Renal Impairment | Dose adjustment may be necessary in patients with renal impairment. Consult a clinician. |
| Hepatic Impairment | Dose adjustment may be necessary in patients with hepatic impairment. Consult a clinician. |
| Maximum Daily Dose | Not established from the available information. |
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of spirodin injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ciprofloxacin | Major | |
| Propranolol | Major | |
| Phenytoin | Moderate | |
| Erythromycin | Moderate | |
| Cimetidine | Minor |
🚨 Major Interactions
- Ciprofloxacin
- Propranolol
⚡ Moderate Interactions
- Phenytoin
- Erythromycin
🍷 Alcohol Interaction
Avoid alcohol while receiving this medicine as it may increase the risk of side effects such as nausea, dizziness, and rapid heartbeat.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to doxofylline or other methylxanthines","Acute myocardial infarction","Severe cardiac arrhythmias","Severe liver disease"]
⚠️ Warnings & Precautions
["Use with caution in patients with peptic ulcer disease.","Use with caution in patients with hyperthyroidism.","Use with caution in patients with epilepsy.","Use with caution in elderly patients.","Avoid in patients with severe renal impairment."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, cardiac arrhythmias, and seizures. Treatment is supportive and symptomatic. Seek immediate medical attention.
⏰ Missed Dose
Since this medicine is given by a healthcare professional, missed doses are unlikely. If a dose is missed, contact your healthcare provider for guidance.
Additional Safety Advice
This medicine should only be given by a healthcare professional. Inform your doctor if you have heart disease, liver disease, kidney disease, or if you are pregnant or breastfeeding. Avoid alcohol while receiving this medicine. Do not drive or operate machinery until you know how this medicine affects you. Your doctor may monitor your heart rate, blood pressure, and blood levels of the medicine during treatment.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be needed based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning to become pregnant. The safety of this medicine during pregnancy is not well established.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are receiving this medicine, as it may interact with other medications used during surgery.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine, as it may affect heart rate and blood pressure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Consult your doctor before starting any exercise program. Avoid strenuous activities if you experience breathlessness or chest discomfort.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a clinical setting. After administration, you may feel dizzy or restless. Avoid driving or operating machinery until you feel alert.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Your doctor will determine when to stop based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Regular monitoring of heart, liver, and kidney function may be required. Report any persistent side effects to your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be used for maintenance therapy in asthma and COPD.
Evidence: Well-establishedUsed to reduce airway inflammation.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Ensure you are up to date with influenza and pneumococcal vaccinations as respiratory infections can worsen asthma and COPD.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
This medicine is administered by healthcare professionals and is not for self-administration during travel. If you are prescribed this medicine, ensure you carry a copy of your prescription and medical records. Store it as directed and declare it at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within minutes after injection, but the exact onset may vary.
A: This medicine may cause dizziness or restlessness. Avoid driving until you know how it affects you.
A: Consult your doctor. The safety of this medicine during pregnancy is not well established.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be self-administered at home.
Fact: This medicine must be given by a healthcare professional in a clinical setting. - Myth: This medicine is safe for everyone.
Fact: It is contraindicated in certain heart and liver conditions.