Speedoxime Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, itching, swelling of face or throat, difficulty breathing.
- Severe diarrhea: watery or bloody stools, abdominal cramps, fever.
- Seizures: uncontrolled shaking or convulsions.
- Signs of liver problems: yellowing of skin or eyes, dark urine, severe fatigue.
- Decreased urine output or swelling in legs.
- Unusual bleeding or bruising.
If experiencing severe symptoms, call emergency services immediately.
What is Speedoxime Syrup used for?
This medicine is a combination of cefixime, an antibiotic, and lactobacillus, a probiotic. It is used to treat bacterial infections such as respiratory tract infections, urinary tract infections, and ear infections. The antibiotic kills bacteria, while the probiotic helps maintain gut health.
- Generic Name: Cefixime (50mg) + Lactobacillus (NA)
- Manufacturer: Shreya Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Speedoxime Syrup के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्साइम और लैक्टोबैसिलस का संयोजन है। इसका उपयोग बैक्टीरियल संक्रमण जैसे श्वसन पथ संक्रमण, मूत्र पथ संक्रमण और कान के संक्रमण के इलाज के लिए किया जाता है। सेफिक्साइम बैक्टीरिया को मारता है, जबकि लैक्टोबैसिलस पेट के स्वास्थ्य को बनाए रखने में मदद करता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, मतली, पेट दर्द और ढीले मल शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया, क्लोस्ट्रीडियोइड्स डिफिसाइल-संबंधित दस्त और गुर्दे की समस्या वाले रोगियों में दौरे शामिल हो सकते हैं।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। हर बार उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही खुराक मापने के लिए मापने वाला कप या सिरिंज का उपयोग करें। खुराक न छोड़ें और कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। एंटासिड या आयरन सप्लीमेंट के साथ इस दवा को लेने से बचें, क्योंकि ये अवशोषण को कम कर सकते हैं।
💊 Speedoxime Syrup Uses & Benefits
[{"condition":"Respiratory tract infections","description":"Used to treat bacterial infections of the respiratory tract, such as bronchitis and pharyngitis, caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated urinary tract infections caused by susceptible bacteria like Escherichia coli and Klebsiella species.","evidence":"Well-established"},{"condition":"Ear infections","description":"Prescribed for otitis media caused by susceptible bacteria such as Haemophilus influenzae and Moraxella catarrhalis.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"Used as a single-dose treatment for uncomplicated gonorrhea caused by Neisseria gonorrhoeae.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prophylaxis in dental procedures","description":"Sometimes used off-label to prevent infection in certain dental procedures for patients at risk.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Urinary tract infections, Otitis media, Gonorrhea
📋 Drug Information
| Generic Name(s) | Cefixime (50mg) + Lactobacillus (NA) |
| Brand Name | Speedoxime Syrup |
| Manufacturer | Shreya Life Sciences Pvt Ltd |
| Packaging / Form | bottle of 30 ml Syrup (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Do not freeze. Keep the bottle tightly closed. Discard any unused portion after 14 days if not specified on the label. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefixime, the active antibiotic in this medicine, works by binding to penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final transpeptidation step of peptidoglycan synthesis, which is essential for bacterial cell wall integrity. As a result, the bacterial cell wall becomes weakened, leading to cell lysis and death. Lactobacillus, the probiotic component, helps restore and maintain the natural balance of beneficial bacteria in the gastrointestinal tract, which can be disrupted by antibiotic therapy.
Mechanism Steps
💡 How to Take Speedoxime Syrup
Strength: This medicine is available as an oral suspension containing 50 mg of cefixime per 5 mL, combined with lactobacillus.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 200 mg to 400 mg per day, taken as a single dose or in two divided doses, depending on the type and severity of the infection. For uncomplicated gonorrhea, a single 400 mg dose is recommended. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. The dose is typically based on body weight and the specific infection being treated. |
| Elderly Dosage | Elderly patients may have reduced renal function, which can affect the elimination of cefixime. Dose adjustment may be necessary based on renal function. Consult a doctor for appropriate dosing. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For creatinine clearance (CrCl) 20-40 mL/min, the dose should be reduced to 50% of the usual dose. For CrCl less than 20 mL/min, the dose should be reduced to 25% of the usual dose. Consult a doctor for specific dosing. |
| Hepatic Impairment | No specific dose adjustment is required for hepatic impairment, as cefixime is not significantly metabolized in the liver. However, caution is advised in patients with both hepatic and renal impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is 400 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Speedoxime Syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Carbamazepine | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Warfarin
- Carbamazepine
⚡ Moderate Interactions
- Probenecid
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol may worsen gastrointestinal side effects such as nausea and diarrhea. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cefixime or other cephalosporins","Known allergy to penicillins (cross-reactivity may occur)","Previous history of severe allergic reaction to any beta-lactam antibiotic"]
⚠️ Warnings & Precautions
["Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in patients with a history of gastrointestinal disease, especially colitis.","Prolonged use may result in overgrowth of non-susceptible organisms, including fungi.","May cause false-positive results in urine glucose tests.","Do not use for viral infections; it is ineffective against viruses.","Complete the full course as prescribed to prevent resistance."]
🤱 Lactation Safety
Cefixime is excreted in human breast milk in low concentrations. It is generally considered safe during breastfeeding, but monitor the infant for diarrhea or thrush. Consult your doctor before use.
💊 Overdose Management
Overdose of cefixime may cause nausea, vomiting, abdominal pain, and diarrhea. In severe cases, seizures may occur, especially in patients with renal impairment. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases. Contact a poison control center or emergency room immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Shake the bottle well before each use to ensure the medicine is evenly mixed. Use a proper measuring device to get the correct dose. Do not skip doses or stop the course early, even if you feel better. Complete the full course to prevent the infection from returning and to reduce the risk of antibiotic resistance. Inform your doctor if you have kidney problems, allergies, or are pregnant or breastfeeding. Avoid taking antacids or iron supplements within two hours of this medicine, as they can reduce its absorption. Store the syrup as directed on the label, and discard any unused portion after the recommended period.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function, which can affect the elimination of cefixime. Dose adjustment may be necessary. Monitor for signs of toxicity.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may interact with other medications used during surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may affect the choice of antibiotics for prophylaxis.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can continue light exercise if you feel up to it, but avoid strenuous activities if you have fever or fatigue. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Complete the full course as prescribed. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless prescribed by a doctor. Prolonged use may lead to antibiotic resistance and superinfections. Regular monitoring of kidney and liver function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help maintain gut health during antibiotic therapy.
Evidence: Well-establishedHelps flush out bacteria from the urinary tract.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics like cefixime may reduce the effectiveness of live bacterial vaccines such as the typhoid vaccine. Consult your doctor about vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store the syrup at room temperature and protect it from extreme heat or cold. If traveling across time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Do not leave the medicine in a hot car or checked luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: It is classified as Pregnancy Category B. It should be used during pregnancy only if clearly needed. Consult your doctor.
A: No, you must complete the full course as prescribed to prevent the infection from returning and to reduce antibiotic resistance.
🤔 Common Patient Concerns
🔄 Substitutes for Speedoxime Syrup
View AllAlternative brands with exact same active ingredient:
-
ceflora syrupThemis Medicare Ltd ₹35.33 24.6% COSTLIER
-
cefigard syrupVanguard Therapeutics Pvt Ltd ₹44.75 57.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: Antibiotics are only effective against bacterial infections. They do not work against viruses. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to reduce antibiotic resistance. - Myth: Probiotics in antibiotics are unnecessary.
Fact: Probiotics like lactobacillus can help reduce antibiotic-associated diarrhea and maintain gut health.
🔄 Alternative Options
Generic Alternatives
- Cefixime oral suspension
- Cefixime and lactobacillus oral suspension
Brand Alternatives
- Speedoxime Syrup