aspisol 150 tablet - Aspirin (150mg) + Glycine (75mg) medicine

aspisol 150 tablet

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🏭 Shreya Life Sciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is aspisol 150 tablet used for?

This medicine contains Aspirin (150mg) + Glycine (75mg) and is used to treat CARDIAC. Irreversibly acetylates cyclooxygenase (COX-1 and COX-2), inhibiting thromboxane A2 synthesis, there. Always consult your doctor before use.

  • Generic Name: Aspirin + Glycine
  • Manufacturer: Shreya Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 aspisol 150 tablet Uses & Benefits

Prophylaxis of myocardial infarction, stroke, and other thromboembolic disorders; acute coronary syndromes; pain and inflammation (low doses for antiplatelet effect)

Off-label uses: Prevention of preeclampsia, colorectal cancer prevention

📋 Drug Information

Generic Name(s)Aspirin + Glycine
Brand NameAspisol 150 Tablet
ManufacturerShreya Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAntiplatelet agent, NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture and light
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract
DistributionDistributes widely into body tissues and fluids
Protein Binding80-90% bound to plasma proteins
MetabolismHepatic metabolism via hydrolysis to salicylic acid
Half-Life15-20 minutes (aspirin); 2-3 hours (salicylic acid)
ExcretionRenal excretion of salicylic acid and metabolites
Bioavailability50-75% (oral)
Onset of Action30-60 minutes
Peak Plasma Time1-2 hours
Duration of Action4-6 hours

How It Works

Irreversibly acetylates cyclooxygenase (COX-1 and COX-2), inhibiting thromboxane A2 synthesis, thereby reducing platelet aggregation.

Mechanism Steps

1Aspirin irreversibly acetylates serine residue in COX-1 and COX-2 enzymes.
2Inhibition of COX-1 prevents conversion of arachidonic acid to thromboxane A2 in platelets.
3Reduced thromboxane A2 decreases platelet aggregation and vasoconstriction.
4Inhibition of COX-2 reduces prostaglandin synthesis, contributing to anti-inflammatory and analgesic effects.
5Glycine acts as a buffer to reduce gastric irritation.

💡 How to Take aspisol 150 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of aspisol 150 tablet

✅ Common Side Effects

Dyspepsia
Nausea
Vomiting
Gastric irritation
Heartburn

🚨 Serious Side Effects

Gastrointestinal bleeding
Peptic ulcer
Hemorrhagic stroke
Reye's syndrome (children)
Anaphylaxis

⚠️ Rare Side Effects

Hepatotoxicity
Nephrotoxicity
Thrombocytopenia
Aplastic anemia
Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Heparin Major Increased bleeding risk
Clopidogrel Major Increased bleeding risk
Ibuprofen Major Reduced antiplatelet effect of aspirin
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
SSRIs Moderate Increased bleeding risk
Corticosteroids Moderate Increased GI ulcer risk
Alcohol Moderate Increased GI bleeding risk
Antacids Minor Reduced aspirin absorption
Caffeine Minor Increased GI irritation
Phenytoin Minor Increased phenytoin levels

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Heparin
  • Clopidogrel
  • Ibuprofen

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • SSRIs
  • Corticosteroids
  • Alcohol

🍷 Alcohol Interaction

Increased risk of gastrointestinal bleeding

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to aspirin or NSAIDs, active peptic ulcer, bleeding disorders, severe hepatic or renal impairment, third trimester of pregnancy, children with viral infections (Reye's syndrome risk)

🤱 Lactation Safety

Caution; excreted in breast milk; avoid high doses

💊 Overdose Management

Activated charcoal, gastric lavage, supportive care; hemodialysis for severe toxicity

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

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