aspisol 150 tablet - Uses, Price, Side Effects & Substitutes
What is aspisol 150 tablet used for?
Aspisol 150 Tablet (Aspirin + Glycine) is used to treat CARDIAC. It contains Aspirin (150mg) + Glycine (75mg), which Irreversibly acetylates cyclooxygenase (COX-1 and COX-2), inhibiting thromboxane. Always consult your doctor before use. Take as prescribed.
- Generic Name: Aspirin + Glycine
- Manufacturer: Shreya Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ aspisol 150 tablet Uses & Benefits
Prophylaxis of myocardial infarction, stroke, and other thromboembolic disorders; acute coronary syndromes; pain and inflammation (low doses for antiplatelet effect)
Off-label uses: Prevention of preeclampsia, colorectal cancer prevention
๐ Drug Information
| Generic Name(s) | Aspirin + Glycine |
| Brand Name | Aspisol 150 Tablet |
| Manufacturer | Shreya Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antiplatelet agent, NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Irreversibly acetylates cyclooxygenase (COX-1 and COX-2), inhibiting thromboxane A2 synthesis, thereby reducing platelet aggregation.
Mechanism Steps
๐ก How to Take aspisol 150 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aspisol 150 tablet
โ Common Side Effects
- Dyspepsia
- Nausea
- Vomiting
- Gastric irritation
- Heartburn
๐จ Serious Side Effects
- Gastrointestinal bleeding
- Peptic ulcer
- Hemorrhagic stroke
- Reye's syndrome (children)
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Nephrotoxicity
- Thrombocytopenia
- Aplastic anemia
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Heparin | Major | Increased bleeding risk |
| Clopidogrel | Major | Increased bleeding risk |
| Ibuprofen | Major | Reduced antiplatelet effect of aspirin |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic effect |
| SSRIs | Moderate | Increased bleeding risk |
| Corticosteroids | Moderate | Increased GI ulcer risk |
| Alcohol | Moderate | Increased GI bleeding risk |
| Antacids | Minor | Reduced aspirin absorption |
| Caffeine | Minor | Increased GI irritation |
| Phenytoin | Minor | Increased phenytoin levels |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Heparin
- Clopidogrel
- Ibuprofen
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- SSRIs
- Corticosteroids
- Alcohol
โน๏ธ Minor Interactions
- Antacids
- Caffeine
- Phenytoin
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to aspirin or NSAIDs, active peptic ulcer, bleeding disorders, severe hepatic or renal impairment, third trimester of pregnancy, children with viral infections (Reye's syndrome risk)
๐ Monitoring Parameters
Bleeding time, INR (if on anticoagulants), renal function, liver function, signs of GI bleeding
๐คฑ Lactation Safety
Caution; excreted in breast milk; avoid high doses
๐ Overdose Management
Activated charcoal, gastric lavage, supportive care; hemodialysis for severe toxicity
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose