spasmolar tablet - Dicyclomine (10mg) + Clidinium (2.5mg) medicine

Spasmolar Tablet: Complete Guide To Uses, Dosage, And Safety

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🏭 Lark Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for IBS and gastroenteritis; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: rash, swelling of face or throat, difficulty breathing.
  • Fast or irregular heartbeat, chest pain.
  • Confusion, hallucinations, or severe dizziness.
  • Inability to urinate or severe abdominal pain with vomiting.
  • Severe eye pain, redness, or vision loss.
  • Signs of paralytic ileus: severe constipation, bloating, vomiting.

If experiencing severe symptoms, call emergency services immediately.

What is spasmolar tablet used for?

This medicine is a combination of dicyclomine and clidinium used to treat abdominal cramps and spasms in conditions like irritable bowel syndrome. It works by relaxing the smooth muscles of the gut. It is usually taken three to four times a day, but the dose must be prescribed by a doctor.

  • Generic Name: Dicyclomine (10mg) + Clidinium (2.5mg)
  • Manufacturer: Lark Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 spasmolar tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डाइसाइक्लोमिन और क्लिडिनियम का संयोजन है, जिसका उपयोग पेट और आंतों की ऐंठन, दर्द, और सूजन को कम करने के लिए किया जाता है। यह इरिटेबल बोवेल सिंड्रोम (IBS), गैस्ट्रोएंटेराइटिस, और पित्त नली की ऐंठन में राहत देती है। यह दवा मांसपेशियों को आराम देकर काम करती है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, धुंधली दृष्टि, नींद आना, चक्कर आना, कब्ज, और पेशाब करने में कठिनाई शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको तेज़ धड़कन, भ्रम, या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे लेते समय गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद और धुंधली दृष्टि हो सकती है। शराब का सेवन न करें। पर्याप्त पानी पिएं और फाइबर युक्त भोजन करें। यदि आपको ग्लूकोमा, मायस्थेनिया ग्रेविस, या पेशाब की समस्या है, तो डॉक्टर को बताएं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 spasmolar tablet Uses & Benefits

[{"condition":"Irritable bowel syndrome (IBS)","description":"Helps relieve abdominal pain, cramping, and bloating associated with IBS by reducing smooth muscle spasms in the intestines.","evidence":"Well-established"},{"condition":"Gastroenteritis","description":"Used to reduce abdominal cramps and discomfort caused by inflammation of the stomach and intestines.","evidence":"Moderate"},{"condition":"Biliary colic","description":"May help relieve pain from spasms of the bile ducts or gallbladder.","evidence":"Limited"},{"condition":"Urinary tract spasms","description":"Can be used to relax smooth muscle spasms in the urinary tract, such as in renal colic.","evidence":"Limited"},{"condition":"Peptic ulcer disease","description":"Sometimes used as an adjunct to reduce gastric motility and secretions, though not a primary treatment.","evidence":"Limited"}]

Off-label uses: [{"condition":"Menstrual cramps","description":"Occasionally prescribed off-label to relieve uterine cramps, but evidence is limited.","evidence":"Limited"},{"condition":"Infantile colic","description":"Not recommended due to safety concerns in infants; off-label use is discouraged.","evidence":"Insufficient"}]

Primary treatment for: Irritable bowel syndrome

Also treats: Gastroenteritis, Biliary colic, Urinary tract spasms, Peptic ulcer disease

📋 Drug Information

Generic Name(s)Dicyclomine (10mg) + Clidinium (2.5mg)
Brand Namespasmolar tablet
ManufacturerLark Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed; do not adjust the dose on your own.
2
Take it before meals for best effect on gastrointestinal spasms.
3
Avoid driving or operating machinery until you know how it affects you.
4
Stay hydrated and eat fiber-rich foods to prevent constipation.
5
Do not use this medicine for more than a few days without consulting your doctor.
6
Inform your doctor if you have glaucoma, urinary retention, or heart problems.
7
Report any severe or persistent side effects immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal cramps
This medicine is commonly prescribed for this.
Likely Use
✅
Bloating
This medicine can help relieve bloating associated with spasms.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Headache
This medicine is not indicated for headache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDicyclomine is well absorbed from the gastrointestinal tract after oral administration. Clidinium absorption is also adequate, though specific bioavailability data are not well established. Food may delay absorption slightly but does not significantly affect the extent.
DistributionBoth drugs are distributed widely in the body. Dicyclomine crosses the blood-brain barrier to some extent, which can cause central nervous system effects. Clidinium, being a quaternary ammonium compound, has limited central nervous system penetration. Protein binding data are not well established for the combination.
Protein BindingNot established from the available information.
MetabolismDicyclomine is metabolized in the liver, primarily by oxidation and conjugation. Clidinium is also metabolized in the liver, but specific pathways are not fully characterized.
Half-LifeThe elimination half-life of dicyclomine is approximately 1.8 to 2.5 hours. The half-life of clidinium is not well established.
ExcretionBoth drugs and their metabolites are excreted primarily in the urine and feces. Dicyclomine is mainly excreted in urine as metabolites.
BioavailabilityThe oral bioavailability of dicyclomine is approximately 50% to 60%. The bioavailability of clidinium is not well established.
Onset of ActionAntispasmodic effects usually begin within 1 to 2 hours after oral administration.
Peak Plasma TimePeak plasma concentrations of dicyclomine are reached about 1 to 2 hours after oral dosing. The peak time for clidinium is not well established.
Duration of ActionThe antispasmodic effect typically lasts for 4 to 6 hours, so dosing is usually three to four times daily.

How It Works

This medicine combines two antispasmodic agents with anticholinergic properties. Dicyclomine acts primarily on muscarinic receptors in the smooth muscle of the gastrointestinal tract, reducing muscle spasms by blocking acetylcholine-induced contractions. Clidinium is a quaternary ammonium anticholinergic that also blocks muscarinic receptors, leading to relaxation of smooth muscle and decreased secretions. Together, they reduce hypermotility and spasm in the gut, biliary tract, and urinary tract, providing symptomatic relief.

Mechanism Steps

1
Binding to muscarinic receptors: Dicyclomine and clidinium competitively bind to muscarinic acetylcholine receptors on smooth muscle cells.
2
Blockade of acetylcholine action: This prevents acetylcholine from stimulating the receptors, thereby reducing muscle contraction.
3
Smooth muscle relaxation: The blockade leads to relaxation of smooth muscle in the gastrointestinal, biliary, and urinary tracts.
4
Reduction of spasms and motility: The relaxed muscle reduces spasm frequency and intensity, relieving pain and cramping.
5
Decreased secretions: Anticholinergic action also reduces gastric, salivary, and other secretions.

💡 How to Take spasmolar tablet

Strength: Tablet containing dicyclomine 10 mg and clidinium 2.5 mg.

1Take this medicine orally with a glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take it before meals or as directed by your doctor.
4Take it at the same times each day to maintain consistent levels.
5If it causes stomach upset, you may take it with food.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken three to four times daily, preferably before meals and at bedtime. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, and renal and hepatic function. Do not exceed the prescribed dose. This medicine is for short-term use unless otherwise directed by your doctor.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients are more sensitive to anticholinergic effects and may require a lower dose. Use with caution and monitor closely for confusion, constipation, and urinary retention. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment may be necessary in patients with renal impairment. Consult a doctor for individualized dosing.
Hepatic ImpairmentDose adjustment may be necessary in patients with hepatic impairment. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 4 tablets (40 mg dicyclomine and 10 mg clidinium) in divided doses, but this must be confirmed by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
High-fiber foods
Take with plenty of water
Helps prevent constipation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of spasmolar tablet

✅ Common Side Effects

Dry mouth (Common (10-30%))
Sip water, chew sugar-free gum, or use saliva substitutes. Consult doctor if severe.
Blurred vision (Common (5-15%))
Avoid driving if affected. Usually temporary. Consult doctor if persistent.
Drowsiness (Common (5-10%))
Avoid alcohol and driving. Consult doctor if it interferes with daily activities.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Consult doctor if persistent.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if severe or persistent.
Nausea (Common (5-10%))
Take with food. Consult doctor if persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling of face or throat, or difficulty breathing.
Fast or irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you notice palpitations or chest discomfort.
Confusion or hallucinations (Rare (<0.1%))
Stop the medicine and consult a doctor immediately.
Urinary retention (Rare (<0.1%))
Seek medical attention if you are unable to urinate.
Angle-closure glaucoma (Rare (<0.1%))
Seek immediate ophthalmological care if you experience severe eye pain, redness, or vision loss.

⚠️ Rare Side Effects

Paralytic ileus
Seek immediate medical attention if you have severe abdominal pain, vomiting, and inability to pass stool or gas.
Severe skin reactions (Stevens-Johnson syndrome)
Stop the medicine and seek emergency care if you develop rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Atropine Major
Benztropine Major
Amitriptyline Moderate
Morphine Moderate
Aluminum hydroxide Moderate
Levodopa Minor
Prednisolone Minor
Warfarin Minor
Metformin Minor
Omeprazole Minor

🚨 Major Interactions

  • Other anticholinergic drugs (e.g., atropine, benztropine, antihistamines)
  • MAO inhibitors
  • Potassium chloride (solid oral dosage forms)

⚡ Moderate Interactions

  • Tricyclic antidepressants (e.g., amitriptyline)
  • Opioid analgesics
  • Antacids (aluminum or magnesium based)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair mental alertness. It may also worsen anticholinergic side effects such as dry mouth and blurred vision.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to dicyclomine, clidinium, or any component of the formulation","Glaucoma (angle-closure)","Myasthenia gravis","Urinary retention","Severe ulcerative colitis","Toxic megacolon","Obstructive uropathy","Paralytic ileus","Infants less than 6 months of age"]

⚠️ Warnings & Precautions

["May cause drowsiness and blurred vision; avoid driving or operating machinery until effects are known.","Avoid alcohol and other central nervous system depressants.","Use with caution in elderly patients due to increased risk of confusion, constipation, and urinary retention.","Use with caution in patients with autonomic neuropathy, hyperthyroidism, coronary heart disease, congestive heart failure, cardiac arrhythmias, hiatal hernia, and reflux esophagitis.","May worsen diarrhea in patients with ulcerative colitis; monitor closely.","Do not use for prolonged periods without medical supervision.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Dicyclomine and clidinium may pass into breast milk and could cause anticholinergic effects in the infant. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose of this medicine can cause severe anticholinergic symptoms such as dry mouth, flushing, dilated pupils, blurred vision, tachycardia, urinary retention, confusion, hallucinations, and seizures. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and symptomatic, including gastric lavage if within 1-2 hours of ingestion, activated charcoal, and management of specific symptoms. Physostigmine may be used cautiously in severe cases under medical supervision.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Avoid driving or operating heavy machinery until you know how this medicine affects you, because it can cause drowsiness and blurred vision. Do not drink alcohol while taking this medicine, as it can increase drowsiness and dizziness. Stay hydrated and eat a high-fiber diet to prevent constipation. Inform your doctor if you have glaucoma, myasthenia gravis, urinary retention, liver disease, kidney disease, or heart problems before taking this medicine. Do not take this medicine for longer than recommended without consulting your doctor. Keep this medicine out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to anticholinergic effects such as confusion, constipation, and urinary retention. Use with caution and lower doses may be required. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established, and it should only be used if clearly needed.

🏥 Post-Surgery Considerations

This medicine may affect bowel motility and urinary function after surgery. Inform your surgeon and anesthesiologist if you are taking this medicine before any surgery. It may need to be stopped temporarily.

🦷 Dental Procedures

This medicine can cause dry mouth, which may increase the risk of dental problems. Inform your dentist if you are taking this medicine before any dental procedure. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce abdominal pressure.
🥗
Eat small, frequent meals to ease digestion.
😴
Avoid trigger foods that worsen your symptoms.
💧
Practice stress-reducing techniques like yoga or meditation.
🧘
Get regular exercise to promote healthy digestion.
🌞
Stay well hydrated throughout the day.

🏋️ Exercise Considerations

This medicine may cause drowsiness and blurred vision, so avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light exercise like walking is generally safe.

🥗 Diet Recommendations

Include fiber-rich foods like fruits, vegetables, and whole grains.
Avoid spicy, fatty, and processed foods that can trigger spasms.
Stay well hydrated by drinking plenty of water.
Limit caffeine and carbonated drinks.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and blurred vision, which may affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job requires alertness.

🛑 When to Stop This Medicine

Do not stop taking this medicine abruptly without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor will advise you on whether to stop or adjust the dose.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to persistent anticholinergic effects such as constipation, dry mouth, and urinary retention. It may also mask underlying conditions. Regular monitoring by a doctor is recommended if prolonged use is necessary. Do not use for extended periods without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Avoiding trigger foods and eating a balanced diet can help reduce IBS symptoms.

Evidence: Well-established
Stress management

Techniques like yoga, meditation, and counseling can reduce stress-related gut symptoms.

Evidence: Moderate
Probiotics

May help restore gut flora balance and reduce symptoms in some patients.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before any vaccination if you are unwell.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust dosing times gradually to maintain consistent intervals. Check local customs regulations regarding prescription medicines before you travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with irritable bowel syndrome
She experienced frequent abdominal cramps and bloating. Her doctor prescribed this medicine three times a day. After a week, her cramps reduced significantly, and she could eat without discomfort. She learned to take it before meals and to avoid alcohol.
💡 Lesson: Taking the medicine as prescribed and making lifestyle changes can greatly improve IBS symptoms.
👤 A 50-year-old man with biliary colic
He had severe right upper abdominal pain after fatty meals. This medicine was prescribed to relieve spasms. He felt relief within an hour of taking it. He was advised to follow a low-fat diet and to report if pain persisted.
💡 Lesson: This medicine provides symptomatic relief but does not treat the underlying cause; dietary changes are important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving spasms within 1 to 2 hours after taking a dose.

Q: Can I take it with other medicines?

A: It can interact with other anticholinergic drugs, antidepressants, and opioids. Always inform your doctor about all medicines you take.

Q: Is it safe during pregnancy?

A: The safety during pregnancy is not well established. Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant.

Q: What should I do if I miss a dose?

A: Take the missed dose as soon as you remember, but if it is almost time for the next dose, skip it and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure irritable bowel syndrome.
    Fact: This medicine only relieves symptoms like cramps and spasms; it does not cure the underlying condition.
  • Myth: It is safe to take this medicine for months without a doctor's supervision.
    Fact: Prolonged use should be monitored by a doctor due to potential side effects and the need to reassess the condition.
  • Myth: This medicine is safe for infants with colic.
    Fact: It is not recommended for infants under 6 months and should not be used for colic without medical advice.

🔄 Alternative Options

Generic Alternatives

  • Dicyclomine 10 mg + Clidinium 2.5 mg tablet

Brand Alternatives

  • Spasmolar Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Dicyclomine alone","composition":"Dicyclomine 10 mg","uses":"IBS, abdominal cramps","notes":"Single agent; may have fewer anticholinergic effects than combination."},{"medicine":"Clidinium alone","composition":"Clidinium 2.5 mg","uses":"Peptic ulcer, IBS","notes":"Often combined with other drugs; less commonly used alone."},{"medicine":"Mebeverine","composition":"Mebeverine 135 mg","uses":"IBS","notes":"Antispasmodic with fewer anticholinergic side effects."}]

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