alfa betalar injection - Arteether (NA) medicine

alfa betalar injection

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Arteether (NA)
🏭 Lark Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

What is alfa betalar injection used for?

This medicine contains Arteether (NA) and is used to treat ANTI MALARIALS. Arteether is converted to dihydroartemisinin, which generates free radicals that damage parasite pro. Always consult your doctor before use.

  • Generic Name: Arteether
  • Manufacturer: Lark Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 alfa betalar injection Uses & Benefits

Treatment of uncomplicated and severe falciparum malaria; chloroquine-resistant malaria.

Off-label uses: Babesiosis (limited evidence); autoimmune diseases (not recommended).

📋 Drug Information

Generic Name(s)Arteether
Brand NameArtisun 150mg Injection
ManufacturerLark Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI MALARIALS
Action ClassAntimalarial- Artemisinin and derivatives
Route of AdministrationIntramuscular injection only
StorageStore at 20-25°C; protect from light; do not freeze.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular injection; peak plasma concentrations achieved within 2-3 hours.
DistributionWidely distributed in body tissues; crosses blood-brain barrier.
Protein BindingApproximately 95% bound to plasma proteins.
MetabolismMetabolized in the liver primarily by CYP2A6 to dihydroartemisinin (active metabolite).
Half-LifeApproximately 23 hours for arteether; 4-11 hours for dihydroartemisinin.
ExcretionPrimarily excreted in urine (up to 80%) and feces.
BioavailabilityNot applicable (parenteral administration); high systemic availability.
Onset of ActionRapid onset; clinical improvement within 24-48 hours.
Peak Plasma Time2-3 hours after intramuscular injection.
Duration of ActionLong-acting; single dose provides therapeutic levels for several days.

How It Works

Arteether is converted to dihydroartemisinin, which generates free radicals that damage parasite proteins and membranes.

Mechanism Steps

1Arteether is hydrolyzed to dihydroartemisinin (DHA) in the liver.
2DHA interacts with heme (from hemoglobin digestion) in the parasite.
3Formation of free radicals (carbon-centered radicals) via cleavage of endoperoxide bridge.
4Free radicals alkylate parasite proteins and membranes, causing oxidative stress.
5Disruption of parasite's detoxification pathways and mitochondrial function.
6Rapid parasite death and clearance from blood.

💡 How to Take alfa betalar injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of alfa betalar injection

✅ Common Side Effects

Headache
Dizziness
Nausea
Vomiting
Abdominal pain
Injection site pain

🚨 Serious Side Effects

QTc prolongation
Severe hemolysis (in G6PD deficiency)
Hepatotoxicity
Allergic reactions

⚠️ Rare Side Effects

Neurotoxicity (ataxia, tremors)
Hemolytic anemia
Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Mefloquine Major Increased risk of neuropsychiatric effects and QTc prolongation
Quinine Major Additive cardiotoxicity (QTc prolongation)
Halofantrine Major Increased risk of fatal cardiac arrhythmias
Ketoconazole Moderate Increased arteether levels due to CYP2A6 inhibition
Rifampin Moderate Decreased arteether efficacy due to CYP2A6 induction
Warfarin Minor Possible increased INR; monitor
Carbamazepine Minor Possible decreased arteether levels

🚨 Major Interactions

  • Mefloquine
  • Quinine
  • Halofantrine

⚡ Moderate Interactions

  • CYP2A6 inhibitors (e.g., ketoconazole)
  • CYP2A6 inducers (e.g., rifampin)

🍷 Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to arteether or artemisinin derivatives; severe hepatic impairment.

🤱 Lactation Safety

Excreted in breast milk; caution advised; discontinue breastfeeding or drug.

💊 Overdose Management

Symptomatic and supportive treatment; no specific antidote; monitor ECG and liver function.

⏰ Missed Dose

Administer as soon as remembered; do not double dose; maintain dosing interval.

🔄 Substitutes for alfa betalar injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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