Doxvit 6 Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or wheezing
- Severe dizziness or fainting
- Confusion, hallucinations, or unusual behaviour
- Inability to pass urine or severe lower abdominal pain
- Persistent fast or irregular heartbeat
- Yellowing of the skin or eyes, or dark urine
- Severe drowsiness that interferes with daily activities
If experiencing severe symptoms, call emergency services immediately.
What is sify 6 tablet used for?
This medicine is a combination of doxylamine and vitamin B6 (pyridoxine) used mainly to treat nausea and vomiting of pregnancy. It is usually taken at bedtime because it can cause drowsiness. It should only be used under medical supervision, and the dose must be individualized by a doctor.
- Generic Name: Doxylamine (NA) + Vitamin B6 (Pyridoxine) (NA)
- Manufacturer: Aamorb Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sify 6 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डॉक्सिलामाइन और विटामिन बी6 (पाइरिडॉक्सिन) का संयोजन है, जिसका उपयोग मुख्य रूप से गर्भावस्था के दौरान होने वाली मतली और उल्टी (मॉर्निंग सिकनेस) के इलाज के लिए किया जाता है। यह आमतौर पर रात को सोने से पहले ली जाती है क्योंकि इससे नींद आ सकती है। यह दवा डॉक्टर की सलाह के बिना नहीं लेनी चाहिए, और खुराक डॉक्टर द्वारा तय की जानी चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, धुंधली दृष्टि और कब्ज शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। कभी-कभी भ्रम, बेचैनी या पेशाब करने में कठिनाई हो सकती है। गंभीर एलर्जी, बेहोशी या साँस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर रात को सोने से पहले। दवा लेने के बाद गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह आप पर कैसे असर करती है। शराब और नींद लाने वाली अन्य दवाओं से बचें। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। दवा को बच्चों की पहुँच से दूर, ठंडी और सूखी जगह पर रखें।
💊 sify 6 tablet Uses & Benefits
[{"condition":"Nausea and vomiting of pregnancy","description":"This medicine is commonly used to reduce nausea and vomiting during pregnancy, especially when symptoms are persistent or affect daily life.","evidence":"Well-established"},{"condition":"Morning sickness","description":"It helps control the nausea and vomiting that many people experience in early pregnancy, often taken at bedtime to reduce next-morning symptoms.","evidence":"Well-established"},{"condition":"Nausea associated with other causes","description":"In some situations, this combination may be used for nausea from other causes, but only under medical supervision.","evidence":"Limited"}]
Off-label uses: [{"condition":"Insomnia","description":"Doxylamine alone is sometimes used as a short-term sleep aid, but this combination product is not primarily intended for insomnia.","evidence":"Limited"},{"condition":"Motion sickness","description":"Antihistamines like doxylamine may help motion sickness, but this specific combination is not a standard first-choice treatment.","evidence":"Limited"}]
Primary treatment for: Nausea and vomiting of pregnancy
Also treats: Morning sickness, Nausea from other causes (under medical supervision)
📋 Drug Information
| Generic Name(s) | Doxylamine (NA) + Vitamin B6 (Pyridoxine) (NA) |
| Brand Name | sify 6 tablet |
| Manufacturer | Aamorb Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from moisture, heat, and direct sunlight. Keep the tablets in their original container with the lid tightly closed. |
| Shelf Life | Not established from the available information for this specific product. Check the expiry date on the pack. |
| WHO Guideline | Not established from the available information for this specific product. Guidelines for nausea and vomiting of pregnancy may recommend doxylamine and pyridoxine as one treatment option, but you should follow the advice of your own doctor. |
| ICMR Guideline | Not established from the available information for this specific product. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Doxylamine is a first-generation antihistamine that blocks histamine H1 receptors in the brain, which reduces nausea and vomiting and also causes drowsiness. Pyridoxine is converted in the body to pyridoxal phosphate, an active form of vitamin B6 that supports many enzyme reactions involved in neurotransmitter metabolism, including the production of serotonin and gamma-aminobutyric acid. By supporting these pathways, pyridoxine helps reduce nausea. Together, the two ingredients reduce the nausea and vomiting signals that travel through the brain and gut.
Mechanism Steps
💡 How to Take sify 6 tablet
Strength: Immediate-release tablet. The exact strength of doxylamine and vitamin B6 in this product is not established from the available information.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken at bedtime, but the exact dose and frequency depend on the condition being treated, the severity of symptoms, age, kidney function, and liver function. Some people may need a different schedule, such as one tablet at bedtime and another in the morning if advised by their doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose or take extra tablets without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults are more sensitive to the sedative and anticholinergic effects of this medicine. They may need a lower dose or a different treatment, and they should be monitored for confusion, dizziness, falls, and difficulty passing urine. Dose must be individualized by a qualified clinician. |
| Renal Impairment | People with severe kidney disease may need a lower dose or careful monitoring because doxylamine and pyridoxine are excreted in the urine. Dose must be individualized by a qualified clinician based on kidney function. |
| Hepatic Impairment | People with severe liver disease should use this medicine with caution because doxylamine is metabolized in the liver. A lower dose or alternative treatment may be needed. Dose must be individualized by a qualified clinician based on liver function. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information for this specific product. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sify 6 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Opioids | Major | |
| MAOIs | Major | |
| Tricyclic antidepressants | Moderate | |
| Levodopa | Moderate | |
| Antihypertensives | Moderate | |
| Antacids | Minor | |
| Pyridoxine supplements | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Alcohol
- Other central nervous system depressants (for example, benzodiazepines, opioids, sleeping pills)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Anticholinergic medicines (for example, tricyclic antidepressants, some bladder medicines)
- Levodopa
- Antihypertensive medicines
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it increases drowsiness, dizziness, and the risk of falls or accidents. Alcohol can also worsen dry mouth, blurred vision, and difficulty concentrating. If you drink alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to doxylamine, pyridoxine, or any other ingredient in this medicine","Untreated narrow-angle glaucoma","Severe urinary retention or bladder neck obstruction","Severe liver disease","Severe breathing problems such as sleep apnoea","Use in premature infants or neonates","Concurrent use with monoamine oxidase inhibitors"]
⚠️ Warnings & Precautions
["This medicine can cause significant drowsiness. Do not drive or operate machinery until you know how it affects you.","Avoid alcohol and other sedating medicines unless approved by your doctor.","Use with caution in older adults because of increased risk of confusion, falls, and urinary retention.","Tell your doctor if you have glaucoma, an enlarged prostate, difficulty passing urine, asthma, or heart disease.","Do not take more than the prescribed dose, and do not use for longer than advised without medical review.","If you are pregnant or breastfeeding, use only under medical supervision.","Keep this medicine out of reach of children."]
🤱 Lactation Safety
Doxylamine may pass into breast milk and could cause drowsiness in a breastfed infant. Pyridoxine is present in breast milk and is generally considered safe in normal amounts. Breastfeeding mothers should use this medicine only if prescribed by a doctor, and they should watch the baby for excessive sleepiness or poor feeding.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, confusion, agitation, hallucinations, fast heartbeat, low blood pressure, seizures, and breathing difficulty. If you suspect an overdose, seek emergency medical help immediately. Do not try to make yourself vomit unless instructed by a healthcare professional. Treatment is supportive and may include monitoring of breathing, heart rate, and blood pressure, and use of appropriate medicines if needed.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is still close to the scheduled time. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually at bedtime to reduce daytime drowsiness. Do not drive, operate heavy machinery, or perform activities requiring full alertness until you know how this medicine affects you. Avoid alcohol and other medicines that cause drowsiness, such as sleeping pills, anxiety medicines, and certain pain relievers, unless your doctor approves. Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding, because the dose and suitability may need review. Do not take more than the prescribed dose, and do not use it for longer than advised without medical review. Keep all follow-up appointments so your doctor can check your response and adjust treatment if needed. Store this medicine in its original container, away from moisture, heat, and direct sunlight, and keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more sensitive to the sedative and anticholinergic effects of this medicine. They may experience confusion, dizziness, falls, dry mouth, constipation, and difficulty passing urine. A lower dose or a different treatment may be needed, and close monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss this medicine with your doctor before use. It is commonly used for nausea and vomiting during pregnancy, but it should only be taken under medical supervision. Do not start or stop this medicine without medical advice.
🏥 Post-Surgery Considerations
After surgery, this medicine may increase drowsiness and interact with anaesthetic medicines and pain relievers. Tell your surgeon and anaesthetist about all medicines you take, and follow their advice about when it is safe to restart this medicine.
🦷 Dental Procedures
This medicine can cause dry mouth, which may increase the risk of dental problems. Tell your dentist if you take this medicine, especially before any dental procedure that requires sedation or anaesthesia, because it can add to the sedative effects.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Because this medicine can cause drowsiness and dizziness, avoid strenuous exercise or activities that require balance until you know how it affects you. Light activities such as walking are usually fine, but stop and rest if you feel dizzy or faint.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and blurred vision, which may affect your ability to drive, operate machinery, or concentrate at work. It is usually taken at bedtime to reduce daytime effects, but some people may still feel sleepy the next morning. Avoid driving or risky tasks until you know how this medicine affects you.
🛑 When to Stop This Medicine
Do not stop this medicine suddenly without talking to your doctor, especially if you have been taking it regularly. Your doctor will advise you when and how to stop based on your condition and response to treatment. If you experience serious side effects, stop the medicine and seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use of this medicine should be reviewed regularly by a doctor. Prolonged use may increase the risk of tolerance to its sedative effects, persistent dry mouth, constipation, and, in older adults, confusion or falls. There is no strong evidence that it causes serious organ damage at usual doses, but liver and kidney function may need monitoring in people with existing disease. Do not continue this medicine for longer than advised without a medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Small, frequent meals and avoiding trigger foods can help reduce nausea.
Evidence: Well-establishedSome people find ginger helpful for mild nausea, but evidence is limited and it should be discussed with a doctor during pregnancy.
Evidence: LimitedThese may help some people with mild nausea, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are unwell with fever or severe symptoms, your doctor may advise delaying vaccination until you recover.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the lid tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label visible. Keep a copy of your prescription with you, especially for international travel. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, ask your doctor how to adjust the timing of your dose. Do not leave the medicine in a hot car or in checked luggage where it may be exposed to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts to reduce nausea and cause drowsiness within 30 to 60 minutes after taking it. The full effect may take a few days of regular use.
A: This medicine is commonly used for nausea and vomiting of pregnancy, but it should only be taken when prescribed by a qualified doctor who has assessed your condition.
A: You should not drive or operate machinery until you know how this medicine affects you, because it commonly causes drowsiness and dizziness.
A: If you remember soon after the missed dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double dose.
A: No. Alcohol increases drowsiness, dizziness, and the risk of falls or accidents. Avoid alcohol while taking this medicine.
🤔 Common Patient Concerns
🔄 Substitutes for sify 6 tablet
View AllAlternative brands with exact same active ingredient:
-
novam tabletCure Quick Pharmaceuticals ₹20.56 6.2% CHEAPER
-
doxvit 6 tabletChem + Med Pharmaceuticals ₹28.03 27.9% COSTLIER
-
vomipose tabletDakshinamurti Pharma Pvt. Ltd. ₹28.03 27.9% COSTLIER
-
motizex tabletSymcox Research Lab P Ltd ₹29.30 33.7% COSTLIER
-
vomisafe syrupS.S.M Pharmaceuticals ₹32.02 46.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for everyone.
Fact: This medicine is not safe for everyone. It should be avoided in people with certain eye, urinary, liver, or breathing problems, and it should only be used in pregnancy under medical supervision. - Myth: This medicine can be taken at any time of day without causing drowsiness.
Fact: This medicine commonly causes drowsiness, which is why it is usually taken at bedtime. Daytime doses can affect your ability to drive or concentrate. - Myth: More tablets will work faster.
Fact: Taking more than the prescribed dose can increase the risk of serious side effects such as severe drowsiness, confusion, and breathing problems. Always follow your doctor's instructions.
🔄 Alternative Options
Generic Alternatives
- Doxylamine and pyridoxine combination tablets from other manufacturers
- Doxylamine and pyridoxine combination capsules from other manufacturers
Brand Alternatives
- Doxinate
- Emesafe
- Pregnidoxin
- Doxylamine-Pyridoxine combination products