Scornim S 100 mg/15 mg Capsule - Nimesulide (100mg) + Serratiopeptidase (15mg) medicine

Arsulide S Tablet: Comprehensive Medicine Guide

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🏭 Scortis Lab Pvt Ltd 📦 strip of 10 capsules 💊 Allopathy 📅 Updated: Sep 21, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. This medicine should be avoided during pregnancy, especially in the third trimester, unless clearly needed and prescribed by a doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for short-term use in inflammatory conditions.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is Scornim S 100 mg/15 mg Capsule used for?

This medicine is a combination of nimesulide and serratiopeptidase used for short-term relief of pain, inflammation, and swelling. It works by reducing prostaglandins and breaking down inflammatory proteins. It should be taken with food and only as prescribed.

  • Generic Name: Nimesulide (100mg) + Serratiopeptidase (15mg)
  • Manufacturer: Scortis Lab Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Scornim S 100 mg/15 mg Capsule के बारे में (Hindi Summary)

उपयोग: यह दवा नाइमेसुलाइड और सेरेशियोपेप्टिडेज़ का संयोजन है, जिसका उपयोग दर्द, सूजन और inflammation को कम करने के लिए किया जाता है। यह आमतौर पर सर्जरी के बाद की सूजन, दांत दर्द, मांसपेशियों की चोट, और गठिया के दर्द में राहत के लिए दी जाती है। इसे भोजन के साथ लेना चाहिए और डॉक्टर के बताए अनुसार ही सेवन करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, जलन, दस्त और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, किडनी या लिवर की समस्या, और एलर्जी प्रतिक्रिया हो सकती है। यदि काला मल, खून की उल्टी, तेज पेट दर्द, आंखों या त्वचा का पीलापन, या पेशाब कम आना हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक या अवधि से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब न पिएं। अन्य दर्द निवारक दवाएं बिना डॉक्टर की सलाह के न लें। यदि आपको अल्सर, किडनी या लिवर की बीमारी, हाई ब्लड प्रेशर या हृदय रोग है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। 7-10 दिन से अधिक बिना डॉक्टर की सलाह के न लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 Scornim S 100 mg/15 mg Capsule Uses & Benefits

[{"condition":"Post-operative inflammation and swelling","description":"Reduces swelling and pain after surgical procedures.","evidence":"Well-established"},{"condition":"Dental pain and inflammation","description":"Relieves pain and swelling associated with dental procedures or infections.","evidence":"Well-established"},{"condition":"Musculoskeletal injuries","description":"Helps reduce pain and swelling in sprains, strains, and sports injuries.","evidence":"Moderate"},{"condition":"Osteoarthritis","description":"Provides symptomatic relief of pain and stiffness in osteoarthritis.","evidence":"Moderate"},{"condition":"Acute gout","description":"May be used short-term to relieve pain and inflammation in acute gout attacks.","evidence":"Limited"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine relief, but not first-line.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but other NSAIDs are preferred.","evidence":"Limited"}]

Primary treatment for: Inflammatory conditions with pain and swelling

Also treats: Post-operative swelling, Dental pain, Musculoskeletal injuries, Osteoarthritis, Acute gout

📋 Drug Information

Generic Name(s)Nimesulide (100mg) + Serratiopeptidase (15mg)
Brand NameScornim S 100 mg/15 mg Capsule
ManufacturerScortis Lab Pvt Ltd
Packaging / Formstrip of 10 capsules (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
Do not use this medicine for long-term pain management without medical supervision.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Swelling after injury
This medicine helps reduce swelling and inflammation.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNimesulide is rapidly absorbed from the gastrointestinal tract after oral administration. Serratiopeptidase is absorbed intact through the intestinal mucosa, though the extent of absorption may vary.
DistributionNimesulide is highly protein-bound and distributes widely into body tissues, including synovial fluid. Serratiopeptidase distributes to inflamed tissues.
Protein BindingNimesulide is approximately 99% bound to plasma proteins. Serratiopeptidase binding is not well established.
MetabolismNimesulide is extensively metabolized in the liver, primarily by CYP2C9, to several metabolites. Serratiopeptidase is metabolized by proteolytic enzymes in the body.
Half-LifeThe elimination half-life of nimesulide is approximately 2-5 hours. The half-life of serratiopeptidase is not well established.
ExcretionNimesulide metabolites are excreted mainly in urine and feces. Serratiopeptidase is excreted via urine and feces.
BioavailabilityThe oral bioavailability of nimesulide is approximately 70-80%. The bioavailability of serratiopeptidase is not well established.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration of nimesulide. Serratiopeptidase may take several hours to days to show anti-edema effects.
Peak Plasma TimePeak plasma concentration of nimesulide is reached in about 1.5-3 hours. Peak time for serratiopeptidase is not well established.
Duration of ActionThe analgesic and anti-inflammatory effects of nimesulide last for about 6-8 hours. Serratiopeptidase effects may last longer with repeated dosing.

How It Works

This medicine combines two active ingredients with complementary actions. Nimesulide is a nonsteroidal anti-inflammatory drug that selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, reducing the production of prostaglandins that cause pain, inflammation, and fever. Serratiopeptidase is a proteolytic enzyme that breaks down fibrin and other proteins involved in inflammation, thereby reducing swelling and promoting tissue repair. Together, they provide both anti-inflammatory and anti-edema effects.

Mechanism Steps

1
COX-2 inhibition by nimesulide: Nimesulide selectively binds to and inhibits the COX-2 enzyme, reducing prostaglandin production.
2
Reduced pain and inflammation: Lower prostaglandin levels decrease pain signaling and inflammatory response.
3
Proteolytic action of serratiopeptidase: Serratiopeptidase breaks down fibrin and other proteins that contribute to swelling and inflammation.
4
Enhanced tissue repair: By reducing edema and improving blood flow, serratiopeptidase helps in faster healing.

💡 How to Take Scornim S 100 mg/15 mg Capsule

Strength: Each tablet contains nimesulide 100 mg and serratiopeptidase 15 mg.

1Take the tablet with a full glass of water.
2Swallow it whole; do not crush or chew.
3Take it with food or milk to reduce stomach upset.
4Follow the prescribed dose and duration exactly.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally one to two times daily, preferably after meals. The exact dose and duration depend on the condition being treated and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney impairment. Use with caution and lower doses may be considered. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney disease. Dose reduction may be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose reduction may be necessary. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose of nimesulide is 200 mg. Do not exceed this dose. The maximum daily dose of serratiopeptidase is not well established.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Scornim S 100 mg/15 mg Capsule

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food. If persists, consult doctor.
Stomach pain (Common (5-10%))
Take with food or milk. Avoid alcohol.
Heartburn (Common (5-10%))
Take with food. If severe, consult doctor.
Diarrhea (Uncommon (1-5%))
Stay hydrated. Consult doctor if persistent.
Dizziness (Uncommon (1-5%))
Avoid driving if affected. Consult doctor if persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Liver damage (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue immediately.
Kidney impairment (Rare (<0.1%))
Report decreased urine output or swelling. Seek medical help.
Severe allergic reaction (Rare (<0.1%))
Seek emergency care if you experience swelling of face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Blood disorders
Report unusual bleeding or bruising. Seek medical attention.
Severe skin reactions
Seek immediate medical help if you develop rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
ACE inhibitors Major
Diuretics Major
Lithium Moderate
Methotrexate Moderate
Antihypertensives Moderate
Antacids Minor
Aspirin Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs
  • Corticosteroids
  • ACE inhibitors
  • Diuretics

⚡ Moderate Interactions

  • Lithium
  • Methotrexate
  • Antihypertensives

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and may worsen liver toxicity.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to nimesulide, serratiopeptidase, or any component","Active peptic ulcer or history of recurrent ulcers","Severe kidney disease","Severe liver disease","Heart failure","Bleeding disorders","Pregnancy (especially third trimester)","Breastfeeding","Children below 12 years (safety not established)"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not use for more than 7-10 days without medical advice.","Use with caution in elderly patients.","Inform your doctor if you have a history of ulcers, kidney or liver disease, high blood pressure, or heart problems.","Do not take other NSAIDs or pain relievers without consulting your doctor.","Stop use and consult doctor if you experience signs of allergic reaction, bleeding, or liver problems."]

🤱 Lactation Safety

Not established from the available information. This medicine is not recommended during breastfeeding unless clearly needed. Consult your doctor.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, stomach pain, drowsiness, and gastrointestinal bleeding. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Always take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. Inform your doctor if you have a history of ulcers, kidney or liver disease, high blood pressure, or heart problems. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for more than 7-10 days without medical advice. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution and lower doses may be considered. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended if you are planning pregnancy. Consult your doctor for alternative pain relief options.

🏥 Post-Surgery Considerations

This medicine is often prescribed after surgery to reduce swelling and pain. Take it as directed and follow your surgeon's instructions.

🦷 Dental Procedures

This medicine can be used for dental pain and swelling. Inform your dentist if you are taking it before any dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise while taking this medicine, especially if you have pain or swelling. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery if you feel dizzy. It is usually safe to continue desk work.

🛑 When to Stop This Medicine

Stop taking this medicine if you experience signs of allergic reaction, gastrointestinal bleeding, or liver problems. Do not stop abruptly if you are on a prescribed course; consult your doctor first.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to increased risk of gastrointestinal bleeding, ulcers, kidney impairment, and liver toxicity. Regular monitoring of liver and kidney function may be required if prolonged use is necessary. Consult your doctor for alternative treatments if pain persists.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Ice/heat therapy

Helps reduce swelling and pain.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before vaccination if you are on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 30-year-old woman after dental surgery
Prescribed this medicine for post-operative swelling and pain. Took it with meals and used ice packs. Swelling reduced significantly within 3 days. No stomach issues.
💡 Lesson: Taking with food and following post-operative care instructions enhances recovery.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 30-60 minutes after taking the tablet. Anti-swelling effects may take a few hours to days.

Q: Can I take it on an empty stomach?

A: No, it should be taken with food or milk to reduce stomach upset.

Q: Is it safe during pregnancy?

A: It is not recommended during pregnancy, especially in the third trimester. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Scornim S 100 mg/15 mg Capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken long-term for chronic pain.
    Fact: This medicine is for short-term use only. Long-term use increases the risk of serious side effects.
  • Myth: It is safe to take on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset and risk of ulcers.
  • Myth: It can be combined with other pain relievers.
    Fact: Combining with other NSAIDs increases the risk of bleeding and ulcers. Consult your doctor first.

🔄 Alternative Options

Generic Alternatives

  • Nimesulide + Serratiopeptidase combination tablets from other manufacturers

Brand Alternatives

  • Arsulide S Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Nimesulide alone","difference":"Lacks anti-edema effect of serratiopeptidase."},{"medicine":"Serratiopeptidase alone","difference":"Lacks analgesic and anti-inflammatory effect of nimesulide."},{"medicine":"Other NSAID + enzyme combinations","difference":"May have different side effect profiles and efficacy."}]

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