Roxico 150mg Tablet - Roxithromycin (150mg) medicine

Roxid 150 Tablet: Complete Medicine Guide

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🏭 Shreya Life Sciences Pvt Ltd 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Irregular heartbeat or palpitations

If experiencing severe symptoms, call emergency services immediately.

What is Roxico 150mg Tablet used for?

Roxid 150 tablet contains roxithromycin 150 mg, a macrolide antibiotic used to treat bacterial infections of the respiratory tract, skin, and genital tract. It works by stopping bacterial growth. Take it exactly as prescribed, usually once or twice daily, and complete the full course.

  • Generic Name: Roxithromycin (150mg)
  • Manufacturer: Shreya Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Roxico 150mg Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा रॉक्सिथ्रोमाइसिन 150 मिलीग्राम युक्त एक एंटीबायोटिक है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह मुख्य रूप से श्वसन तंत्र के संक्रमण, त्वचा संक्रमण, और कुछ जननांग संक्रमणों के लिए निर्धारित की जाती है। यह दवा बैक्टीरिया के विकास को रोककर काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें और पूरा कोर्स पूरा करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में एलर्जी, लिवर की सूजन, और अनियमित दिल की धड़कन शामिल हो सकते हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। बेहतर महसूस होने पर भी कोर्स बीच में न छोड़ें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। इस दवा के साथ शराब न लें। यदि आपको लिवर, किडनी या दिल की समस्या है तो डॉक्टर को पहले ही बता दें। दवा को कमरे के तापमान पर सूखी जगह पर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 Roxico 150mg Tablet Uses & Benefits

[{"condition":"Community-acquired pneumonia","description":"Used to treat mild to moderate community-acquired pneumonia caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Prescribed for acute exacerbations of chronic bronchitis and acute bronchitis when bacterial infection is suspected.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Effective against skin infections such as cellulitis, erysipelas, and impetigo caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urethritis and cervicitis","description":"Used in the treatment of non-gonococcal urethritis and cervicitis, often caused by Chlamydia trachomatis.","evidence":"Well-established"},{"condition":"Dental infections","description":"Sometimes prescribed for dental abscesses and periodontal infections as an alternative to penicillin.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Occasionally used as part of combination therapy for H. pylori eradication in patients allergic to penicillin.","evidence":"Limited"},{"condition":"Lyme disease","description":"May be used as an alternative in early Lyme disease for patients who cannot take doxycycline or amoxicillin.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Skin infections, Genital tract infections

📋 Drug Information

Generic Name(s)Roxithromycin (150mg)
Brand NameRoxico 150mg Tablet
ManufacturerShreya Life Sciences Pvt Ltd
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full prescribed course even if you feel better.
3
Avoid alcohol while taking this medicine to reduce liver risk.
4
Inform your doctor if you have heart rhythm problems or liver disease.
5
Do not share this medicine with others, even if they have similar symptoms.
6
Report any unusual bleeding, bruising, or yellowing of eyes to your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Persistent cough with fever
This medicine is commonly prescribed for bacterial bronchitis.
Likely Use
Skin redness and swelling
This medicine is used for skin and soft tissue infections.
Likely Use
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRoxithromycin is rapidly absorbed from the gastrointestinal tract after oral administration. Food may slightly reduce the rate but not the extent of absorption. Bioavailability is approximately 50%.
DistributionRoxithromycin distributes widely into body tissues and fluids, including lung tissue, tonsils, prostate, and skin. It achieves high intracellular concentrations, particularly in phagocytes and neutrophils. Protein binding is approximately 86-91%.
Protein BindingApproximately 86-91% bound to plasma proteins, primarily to alpha-1-acid glycoprotein and albumin.
MetabolismRoxithromycin undergoes limited metabolism in the liver, primarily by cytochrome P450 enzymes, though it is less dependent on CYP3A4 than other macrolides. It is metabolized to several inactive metabolites.
Half-LifeThe elimination half-life of roxithromycin is approximately 10-14 hours, allowing for once or twice daily dosing.
ExcretionRoxithromycin is excreted primarily in the feces via bile, with a smaller portion excreted in the urine. About 50-60% of an oral dose is eliminated unchanged in the feces, and 10-15% in the urine.
BioavailabilityApproximately 50% after oral administration.
Onset of ActionThe onset of action is typically within 1-2 hours after oral administration, but clinical improvement may take 24-48 hours.
Peak Plasma TimePeak plasma concentrations are reached approximately 2-4 hours after oral administration.
Duration of ActionThe duration of action is typically 12-24 hours, allowing for once or twice daily dosing.

How It Works

This medicine works by binding to the 50S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis. This action is primarily bacteriostatic, meaning it stops bacteria from growing and multiplying, allowing the body's immune system to eliminate them. It is effective against a range of gram-positive and gram-negative bacteria, as well as atypical pathogens such as Mycoplasma, Chlamydia, and Legionella.

Mechanism Steps

1
Entry into bacterial cell: This medicine penetrates the bacterial cell wall and enters the cytoplasm.
2
Binding to 50S ribosomal subunit: It binds reversibly to the 50S subunit of the bacterial ribosome, specifically to the 23S rRNA component.
3
Inhibition of protein synthesis: This binding blocks the translocation step of protein synthesis, preventing the elongation of polypeptide chains.
4
Bacteriostatic effect: As a result, bacterial growth is halted, and the immune system can clear the infection.

💡 How to Take Roxico 150mg Tablet

Strength: Roxid 150 tablet contains 150 mg of roxithromycin as an immediate-release tablet.

1Take this medicine by mouth with a full glass of water.
2You may take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed by your doctor.
5Complete the full course of therapy even if you feel better after a few days.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 150 mg twice daily or 300 mg once daily, depending on the type and severity of the infection. For some infections, a dose of 150 mg once daily may be sufficient. The duration of treatment varies from 5 to 10 days, but may be longer for certain infections. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. No specific dose adjustment is generally needed unless there is significant renal impairment. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance less than 30 mL/min), dose reduction may be necessary. Monitor renal function and adjust dose as needed. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with severe hepatic impairment, dose reduction or avoidance may be necessary. Monitor liver function. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is 300 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Roxico 150mg Tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or contains blood, contact your doctor.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe or persistent, seek medical advice.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe or persistent.
Vomiting (Uncommon (1-5%))
Take with food and drink plenty of fluids. If vomiting is severe, contact your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing, or dizziness.
Liver inflammation (hepatitis) (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Irregular heartbeat (QT prolongation) (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, dizziness, or fainting.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek emergency care if you develop a painful rash with blisters or peeling skin.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Contact your doctor if you develop severe, persistent diarrhea, especially with blood or mucus.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate medical attention if you experience severe upper abdominal pain radiating to the back, with nausea and vomiting.
Interstitial nephritis
Report decreased urine output, swelling, or fatigue to your doctor.
Hemolytic anemia
Consult your doctor if you experience unusual tiredness, pale skin, or shortness of breath.
Thrombocytopenia
Report unusual bruising or bleeding to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ergot alkaloids Major
Terfenadine Major
Statins Major
Digoxin Major
Carbamazepine Moderate
Cyclosporine Moderate
Theophylline Moderate
Oral contraceptives Moderate
Antacids Minor

🚨 Major Interactions

  • Ergot alkaloids (e.g., ergotamine, dihydroergotamine)
  • Terfenadine, astemizole, cisapride
  • Warfarin
  • Statins (e.g., simvastatin, atorvastatin)
  • Digoxin

⚡ Moderate Interactions

  • Carbamazepine
  • Cyclosporine
  • Theophylline
  • Oral contraceptives
  • Benzodiazepines (e.g., midazolam, triazolam)

🍷 Alcohol Interaction

Alcohol may increase the risk of liver toxicity and gastrointestinal side effects. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to roxithromycin or other macrolide antibiotics","Concomitant use with ergot alkaloids (e.g., ergotamine, dihydroergotamine)","Concomitant use with terfenadine, astemizole, or cisapride","Severe hepatic impairment"]

⚠️ Warnings & Precautions

["Use with caution in patients with liver disease; monitor liver function.","Use with caution in patients with QT prolongation or risk factors for arrhythmias.","May cause Clostridioides difficile-associated diarrhea; consider this diagnosis if diarrhea occurs.","Avoid concomitant use with other QT-prolonging drugs.","May interact with many drugs; review all medications before prescribing.","Not effective against viral infections; do not use for common cold or flu.","Complete the full course as prescribed to prevent resistance."]

🤱 Lactation Safety

Roxithromycin is excreted in human breast milk in small amounts. It is generally considered compatible with breastfeeding, but monitor the infant for diarrhea or thrush. Consult your doctor before use.

💊 Overdose Management

Overdose of roxithromycin may cause severe nausea, vomiting, diarrhea, and hearing loss. There is no specific antidote. Treatment is symptomatic and supportive. Gastric lavage may be considered if ingestion is recent. Contact a poison control center or emergency department immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Inform your doctor about all other medicines, supplements, and herbal products you are taking. Avoid alcohol while on this medicine. If you have liver disease, kidney disease, or heart rhythm problems, tell your doctor before starting this medicine. Do not share this medicine with others. Store it at room temperature away from moisture and heat. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects such as QT prolongation and liver enzyme elevations. Dose adjustment may be needed based on renal function. Monitor closely for any adverse effects.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. It is generally considered safe when clearly needed, but the benefits should outweigh the risks.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may interact with anesthetics and other medications used during surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may interact with certain antibiotics or anesthetics used in dental work.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest to help your body fight the infection.
🥗
Stay well hydrated by drinking plenty of fluids.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Avoid alcohol while taking this medicine.
🧘
Practice good hygiene to prevent the spread of infection.

🏋️ Exercise Considerations

You can continue light exercise if you feel well, but avoid strenuous activities if you have fever or fatigue. Listen to your body and rest when needed.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to maintain gut health.
Stay well hydrated.
Avoid spicy and oily foods if you have stomach upset.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or headache in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, you can continue your normal daily activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and bacterial resistance. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may lead to bacterial resistance and rare side effects such as liver enzyme elevations. Regular monitoring of liver function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Azithromycin

Another macrolide antibiotic with a longer half-life and simpler dosing.

Evidence: Well-established
Amoxicillin

A penicillin antibiotic that may be used for susceptible infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are due for any live vaccines, consult your doctor as antibiotics may affect the immune response to certain vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from moisture and heat. If crossing time zones, adjust dosing times gradually to maintain even intervals. Check customs regulations for carrying prescription medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with a persistent cough and fever
He was diagnosed with acute bronchitis and prescribed this medicine. He took it with food twice daily and completed the 7-day course. His cough and fever improved within 3 days, and he felt completely well by the end of the course.
💡 Lesson: Taking the full course as prescribed and with food improves both efficacy and tolerability.
👤 A 28-year-old woman with a skin infection
She developed cellulitis on her leg and was prescribed this medicine. She experienced mild nausea initially but it subsided when she took it with meals. She completed the 10-day course and the infection cleared completely.
💡 Lesson: Mild side effects can often be managed by taking the medicine with food, and completing the course prevents recurrence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Roxico 150mg Tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure the common cold.
    Fact: This medicine is effective only against bacterial infections, not viral infections like the common cold.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full prescribed course to prevent bacterial resistance and recurrence of infection.
  • Myth: Roxid 150 is safe for everyone.
    Fact: It is not safe for people allergic to macrolides or with certain heart and liver conditions. Always consult a doctor.

🔄 Alternative Options

Generic Alternatives

  • Roxithromycin 150 mg tablet

Brand Alternatives

  • Roxid 150
  • Roxifree 150
  • Roximac 150

📊 Comparison with Similar Medicines

[{"medicine":"Roxithromycin","class":"Macrolide","half_life":"10-14 hours","dosing":"Once or twice daily","common_side_effects":"Nausea, diarrhea, headache"},{"medicine":"Azithromycin","class":"Macrolide","half_life":"68 hours","dosing":"Once daily","common_side_effects":"Diarrhea, nausea, abdominal pain"},{"medicine":"Clarithromycin","class":"Macrolide","half_life":"3-4 hours","dosing":"Twice daily","common_side_effects":"Taste disturbance, nausea, headache"}]

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