Dipsid Plus Cream: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Severe burning, blistering, or peeling of the skin
- Swelling of the face, lips, or throat, or difficulty breathing
- Signs of a new infection such as pus, increased pain, or heat
- Skin thinning, stretch marks, or visible blood vessels
- Feeling very weak, dizzy, or nauseated after using large amounts
- High blood sugar or high blood pressure that is hard to control
- No improvement after two weeks of use
If experiencing severe symptoms, call emergency services immediately.
What is rexiderm plus cream used for?
This medicine is a topical cream containing clobetasol 0.05% and clotrimazole 1%. It is used for a short time to treat inflamed fungal skin infections such as ringworm, jock itch, and athlete's foot. Apply a thin film to the affected skin once or twice daily as directed by your doctor, usually for up to two weeks.
- Generic Name: Clobetasol (0.05% w/w) + Clotrimazole (1% w/w)
- Manufacturer: Dermarex HealthCare India Pvt. Ltd.
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 rexiderm plus cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक क्रीम है जिसमें क्लोबेटासोल 0.05% और क्लोट्रिमाज़ोल 1% होता है। इसका उपयोग दाद, खुजली, एथलीट फुट और जॉक इच जैसे फंगल संक्रमणों में किया जाता है जहाँ सूजन और खुजली भी होती है। यह क्रीम फंगस को मारती है और साथ ही सूजन और खुजली को कम करती है। इसे केवल प्रभावित त्वचा पर पतली परत में लगाएं और डॉक्टर के बताए समय तक ही उपयोग करें।
साइड इफेक्ट्स: इस क्रीम को लगाने पर हल्की जलन, खुजली, सूखापन या लालिमा हो सकती है। लंबे समय तक उपयोग करने से त्वचा पतली हो सकती है, खिंचाव के निशान पड़ सकते हैं या बाल बढ़ सकते हैं। अगर त्वचा पर गंभीर जलन, छाले या संक्रमण बढ़ने के लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस क्रीम को केवल प्रभावित त्वचा पर पतली परत में लगाएं। आंखों, होंठों और मुंह के अंदर न लगाएं। बिना डॉक्टर की सलाह के दो हफ्ते से ज्यादा उपयोग न करें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। बच्चों को डॉक्टर की सलाह के बिना न दें।
💊 rexiderm plus cream Uses & Benefits
[{"condition":"Tinea corporis (ringworm of the body)","description":"Treats ringworm patches that are inflamed, itchy, and red by killing the fungus and reducing inflammation.","evidence":"Well-established"},{"condition":"Tinea cruris (jock itch)","description":"Used for short courses in inflamed jock itch when a doctor confirms a fungal cause.","evidence":"Well-established"},{"condition":"Tinea pedis (athlete's foot)","description":"Helps clear fungal infection between toes and on the soles when inflammation is prominent.","evidence":"Well-established"},{"condition":"Cutaneous candidiasis","description":"Treats yeast infections of the skin folds that are red, macerated, and itchy.","evidence":"Well-established"},{"condition":"Inflammatory dermatophytosis","description":"Reduces severe itching and swelling in fungal skin infections while eradicating the fungus.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Seborrheic dermatitis with suspected fungal component","description":"Sometimes used short-term when both yeast and inflammation are thought to contribute.","evidence":"Limited"},{"condition":"Erythrasma with secondary fungal infection","description":"Occasionally prescribed when a doctor suspects a mixed infection, though antibacterial treatment is usually needed.","evidence":"Limited"}]
Primary treatment for: Inflammatory fungal skin infections
Also treats: Tinea corporis, Tinea cruris, Tinea pedis, Cutaneous candidiasis
📋 Drug Information
| Generic Name(s) | Clobetasol (0.05% w/w) + Clotrimazole (1% w/w) |
| Brand Name | rexiderm plus cream |
| Manufacturer | Dermarex HealthCare India Pvt. Ltd. |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature between 15°C and 30°C. Keep away from direct sunlight and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines a very potent topical corticosteroid with a broad-spectrum antifungal. Clobetasol binds to glucocorticoid receptors inside skin cells, which suppresses inflammatory genes and reduces the release of chemicals that cause redness, swelling, and itching. Clotrimazole works by blocking the synthesis of ergosterol, a key component of fungal cell membranes. Without ergosterol, the fungal membrane becomes leaky and the fungus dies. The corticosteroid does not kill fungi, and the antifungal does not reduce inflammation, so the combination targets both the infection and the inflammatory response at the same time.
Mechanism Steps
💡 How to Take rexiderm plus cream
Strength: Cream containing clobetasol 0.05% w/w and clotrimazole 1% w/w.
Dosage Information
| Adult Dosage | Apply a thin film of this medicine to the affected skin and surrounding area once or twice daily, or as directed by your doctor. The usual duration is up to two weeks. Do not use it for longer than prescribed. Dose must be individualized by a qualified clinician based on the type and severity of the infection, the site of application, and your response to treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 12 years unless prescribed by a specialist. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of topical corticosteroids. Use the smallest amount that works for the shortest time. Consult your doctor for individualized dosing. |
| Renal Impairment | No specific dose adjustment is established for topical use in kidney disease. Use with caution if you have kidney disease and are applying this medicine to large areas. |
| Hepatic Impairment | No specific dose adjustment is established for topical use in liver disease. Use with caution if you have liver disease and are applying this medicine to large areas. |
| Maximum Daily Dose | The maximum daily dose depends on the area of skin treated and the duration of use. Do not exceed the amount prescribed by your doctor. Generally, use the smallest amount that works for the shortest time. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of rexiderm plus cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole (oral) | Major | |
| Ritonavir | Major | |
| Fluconazole | Moderate | |
| Insulin | Moderate | |
| Metformin | Moderate | |
| Warfarin | Minor | |
| Prednisone | Moderate | |
| Hydrocortisone cream | Moderate | |
| Tacrolimus ointment | Moderate | |
| Pimecrolimus cream | Moderate |
🚨 Major Interactions
- Other topical corticosteroids
- CYP3A4 inhibitors such as ketoconazole, itraconazole, or ritonavir
⚡ Moderate Interactions
- Oral antifungal agents such as fluconazole
- Diabetes medicines
🍷 Alcohol Interaction
Alcohol does not directly interact with this topical cream. However, if you use large amounts of this medicine for a long time, alcohol may worsen stomach irritation or liver stress. It is best to avoid heavy drinking while using potent topical steroids.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to clobetasol, clotrimazole, or any ingredient in the cream","Untreated bacterial, viral, or tuberculous skin infections","Acne, rosacea, or perioral dermatitis","Use on the face, groin, or underarms unless specifically directed by a doctor","Children under 12 years unless prescribed by a specialist","Use on broken skin or open wounds"]
⚠️ Warnings & Precautions
["Do not use this medicine for more than two weeks without medical review.","Do not cover the treated area with airtight dressings unless your doctor tells you to.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on large areas of the body for long periods.","If you have diabetes, monitor your blood sugar more closely.","If you have high blood pressure or heart disease, use with caution.","Do not use this medicine to treat diaper rash in children unless prescribed.","Stop using the cream and consult a doctor if the skin infection worsens or spreads."]
🤱 Lactation Safety
It is not known whether clobetasol or clotrimazole passes into breast milk in significant amounts after topical use. To be safe, do not apply this cream to the breast area, and avoid applying it to large areas while breastfeeding. Consult your doctor for guidance.
💊 Overdose Management
Overdose from topical use is unlikely. If someone swallows this cream, seek medical attention immediately. Long-term excessive use can cause systemic steroid effects such as high blood sugar, high blood pressure, and adrenal suppression. Treatment is supportive and may include gradually stopping the steroid under medical supervision.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply a thin film of this medicine only to the affected skin and rub it in gently. Wash your hands before and after applying unless your hands are the treated area. Do not cover the area with bandages, plastic wraps, or tight diapers unless your doctor tells you to. Avoid contact with eyes, lips, and inside the nose or mouth. Do not use this medicine for more than two weeks without medical review. Do not use it on broken skin, open wounds, or areas of bacterial infection. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Do not share this cream with anyone else, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have thinner skin and are more likely to experience skin thinning and other side effects from potent topical steroids. Use the smallest amount that works for the shortest time, and consult your doctor regularly.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. Very potent topical steroids should be avoided in large amounts or for long periods. Your doctor may recommend a safer alternative.
🏥 Post-Surgery Considerations
Do not apply this cream to surgical wounds or broken skin unless your surgeon specifically tells you to. If you develop a fungal infection near a surgical site, consult your doctor before using this medicine.
🦷 Dental Procedures
This medicine is applied to the skin and does not usually affect dental procedures. However, inform your dentist about all medicines you are using, including this cream.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can continue light exercise, but avoid activities that cause excessive sweating or friction on the treated area. Shower and dry the skin gently after exercise before applying the cream. Avoid swimming pools until the infection clears to prevent spreading it to others.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied to the skin and does not usually affect your ability to drive or operate machinery. However, if you feel dizzy or unwell after using large amounts, avoid driving until you feel better. You can continue your normal work routine while using this cream.
🛑 When to Stop This Medicine
Stop using this medicine after the prescribed course is complete, usually within two weeks. If the infection has not cleared, consult your doctor before continuing. Stop immediately and seek medical advice if you notice severe irritation, skin thinning, or signs of a new infection.
📅 Long-Term Use Effects
Long-term use of this medicine can cause skin thinning, stretch marks, visible blood vessels, and increased hair growth. It can also lead to systemic steroid effects such as high blood sugar, high blood pressure, and adrenal suppression if used on large areas for a long time. Regular medical review is needed if you use it for more than two weeks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be sufficient for fungal infections without significant inflammation.
Evidence: Well-establishedMay be needed for extensive or resistant fungal infections, prescribed by a doctor.
Evidence: Well-establishedHelps prevent fungal infections and supports healing.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this topical cream and vaccines. You can receive vaccines while using this medicine.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate or freeze the cream.
✅ DO
Keep the tube tightly closed when not in use.
❌ DON'T
Do not leave the cap off or expose the cream to air for long periods.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet where it may get damp.
✅ DO
Keep out of reach of children.
❌ DON'T
Do not transfer the cream to another container.
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label visible. Keep a copy of your prescription with you, especially when traveling internationally. Store it at room temperature and protect it from direct sunlight and moisture. If you are crossing time zones, continue applying it at your usual times as closely as possible. Check the customs rules of your destination country for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Itching and redness often begin to improve within a few hours to a few days. The fungal infection usually clears within one to four weeks of regular use.
A: No, you should not use this cream on your face unless your doctor specifically tells you to. Very potent steroids can cause skin thinning and other problems on the face.
A: Apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
A: This medicine is generally not recommended for children under 12 years unless prescribed by a specialist. Consult a pediatrician for guidance.
A: Use during pregnancy only if your doctor advises it. Very potent topical steroids should be avoided in large amounts or for long periods during pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for rexiderm plus cream
View AllAlternative brands with exact same active ingredient:
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mixderm creamMDC Pharmaceuticals Pvt Ltd ₹21.68 83.5% CHEAPER
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clojohn-gm creamJohnlee Pharmaceuticals Pvt Ltd ₹31.91 75.7% CHEAPER
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gracederm creamGlenmark Pharmaceuticals Ltd ₹39.67 69.8% CHEAPER
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cortaz nc ointmentTorrent Pharmaceuticals Ltd ₹40.00 69.5% CHEAPER
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ring-out plus creamMankind Pharma Ltd ₹46.88 64.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: This cream is only for fungal skin infections with inflammation. Using it on bacterial or viral rashes can make them worse. - Myth: I can stop using the cream as soon as the rash looks better.
Fact: You should complete the full course prescribed by your doctor to prevent the infection from coming back. - Myth: More cream means faster healing.
Fact: Applying more than a thin film does not speed up healing and increases the risk of side effects. - Myth: This cream is safe to use on the face.
Fact: Very potent steroids like clobetasol can cause skin thinning and other problems on the face. Do not use it on the face unless your doctor specifically tells you to.
🔄 Alternative Options
Generic Alternatives
- Clobetasol 0.05% + Clotrimazole 1% cream (generic)
Brand Alternatives
- Dipsid Plus Cream