Clop-gm Neo Cream: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe burning, blistering, or peeling of the skin
- Signs of a secondary infection such as pus, increased pain, or fever
- Sudden swelling of the face, lips, or throat
- Unusual tiredness, weakness, dizziness, or nausea
- Weight gain, rounding of the face, or easy bruising
- Increased thirst or frequent urination
- Vision changes or eye pain
If experiencing severe symptoms, call emergency services immediately.
What is clojohn-gm cream used for?
This medicine is a prescription cream that combines clotrimazole, an antifungal, with clobetasol, a strong steroid, to treat inflamed fungal skin infections. It should be used thinly on the affected area for a short time, usually up to two weeks, and only under a doctor's supervision.
- Generic Name: Clotrimazole + Clobetasol
- Manufacturer: Johnlee Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 clojohn-gm cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें क्लोट्रिमाज़ोल और क्लोबेटासोल होते हैं। यह फंगल संक्रमण के साथ-साथ सूजन, लालिमा और खुजली को कम करने में मदद करती है। इसका उपयोग त्वचा के फंगल संक्रमण जैसे दाद, खाज-खुजली और पैरों के फंगस के इलाज के लिए किया जाता है, लेकिन केवल डॉक्टर की सलाह पर और सीमित समय के लिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, सूखापन या लालिमा शामिल हैं। लंबे समय तक उपयोग करने पर त्वचा पतली हो सकती है, खिंचाव के निशान पड़ सकते हैं, और शरीर में स्टेरॉयड के दुष्प्रभाव भी हो सकते हैं। अगर आपको गंभीर जलन, छाले या संक्रमण के लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस क्रीम को केवल प्रभावित त्वचा पर पतली परत में लगाएं। आंखों, मुंह और शरीर के अन्य नाजुक हिस्सों पर न लगाएं। बिना डॉक्टर की सलाह के इसे चेहरे, जांघों के बीच या बगल में न लगाएं। निर्धारित समय से ज्यादा इसका इस्तेमाल न करें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। बच्चों से दूर रखें।
💊 clojohn-gm cream Uses & Benefits
[{"condition":"Tinea corporis with inflammation","description":"Treats ringworm of the body when significant redness, swelling, or itching is present.","evidence":"Well-established"},{"condition":"Tinea cruris with inflammation","description":"Treats jock itch when the skin is highly inflamed, but only for short durations under medical supervision.","evidence":"Well-established"},{"condition":"Tinea pedis with inflammation","description":"Treats athlete's foot with marked inflammatory symptoms for a limited period.","evidence":"Well-established"},{"condition":"Candidal intertrigo with inflammation","description":"Treats yeast infections in skin folds when inflammation is prominent, for short-term use.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Inflammatory dermatophytosis unresponsive to plain antifungals","description":"Sometimes used short-term when fungal infection is accompanied by severe eczema-like inflammation.","evidence":"Limited"}]
Primary treatment for: Inflammatory fungal skin infections
Also treats: Tinea corporis, Tinea cruris, Tinea pedis, Candidal intertrigo
📋 Drug Information
| Generic Name(s) | Clotrimazole + Clobetasol |
| Brand Name | Clop-GM Neo Cream |
| Manufacturer | Johnlee Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Antifungal + Corticosteroid |
| Route of Administration | Topical |
| Storage | Store at room temperature between 15°C and 30°C. Keep away from direct sunlight and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary actions. Clotrimazole blocks the synthesis of ergosterol, a vital component of the fungal cell membrane, leading to leakage of cellular contents and fungal death. Clobetasol binds to glucocorticoid receptors in the skin, reducing the production of inflammatory chemicals and suppressing immune cells that cause redness, swelling, and itching. Together, they treat the fungal infection while rapidly calming the inflamed skin.
Mechanism Steps
💡 How to Take clojohn-gm cream
Strength: Cream containing clotrimazole 1% w/w and clobetasol 0.05% w/w.
Dosage Information
| Adult Dosage | Apply a thin film of this medicine to the affected skin area once or twice daily, or as directed by your doctor. The duration of treatment is usually limited to one to two weeks because of the super-potent corticosteroid component. Do not use it for longer than prescribed. Dose must be individualized by a qualified clinician based on the indication, severity of infection, and response to treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 12 years due to the risk of corticosteroid side effects. |
| Elderly Dosage | Elderly patients may be more susceptible to corticosteroid side effects such as skin thinning and adrenal suppression. Use the smallest effective amount for the shortest possible duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for topical use in patients with kidney disease. Systemic absorption is minimal. Consult your doctor if you have severe kidney impairment. |
| Hepatic Impairment | No specific dose adjustment is established for topical use in patients with liver disease. Systemic absorption is minimal. Consult your doctor if you have severe liver impairment. |
| Maximum Daily Dose | Not established from the available information. Use only as prescribed by your doctor. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of clojohn-gm cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other topical corticosteroids | Major | |
| CYP3A4 inhibitors | Major | |
| Nystatin | Moderate | |
| Tacrolimus | Moderate | |
| Pimecrolimus | Moderate |
🚨 Major Interactions
- Other topical corticosteroids
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin)
⚡ Moderate Interactions
- Nystatin
- Tacrolimus or pimecrolimus
🍷 Alcohol Interaction
No direct interaction between this topical cream and alcohol is established. However, alcohol may worsen skin inflammation and should be limited while recovering from a skin infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to clotrimazole, clobetasol, or any component of the cream","Untreated bacterial or viral skin infections","Acne vulgaris, rosacea, and perioral dermatitis","Use on the face, groin, or underarms unless specifically directed by a doctor","Use in children under 12 years unless prescribed by a pediatrician","Use on broken skin or large areas without medical supervision"]
⚠️ Warnings & Precautions
["Do not use this medicine for longer than the prescribed duration, usually not more than two weeks.","Avoid using on the face, groin, or underarms because the skin is thinner and more prone to corticosteroid side effects.","Do not cover the treated area with tight bandages or plastic wrap unless instructed by your doctor.","If you are diabetic, monitor your blood sugar closely because clobetasol can raise glucose levels.","Stop using the cream and consult your doctor if the infection worsens or does not improve after the recommended treatment period.","Inform your doctor if you have a history of glaucoma or cataracts, as corticosteroids can increase eye pressure.","Do not use this medicine as a cosmetic cream or for any condition other than the one prescribed."]
🤱 Lactation Safety
Clotrimazole is generally considered safe for topical use during breastfeeding. Clobetasol should be used with caution, and application to the breast area should be avoided just before feeding to prevent infant exposure. Consult your doctor before use.
💊 Overdose Management
Overdose from topical application is unlikely. If excessive amounts are applied or accidentally ingested, seek medical attention immediately. Prolonged excessive use can lead to systemic corticosteroid effects such as adrenal suppression, high blood sugar, and Cushing's syndrome. Treatment is supportive and may require gradual withdrawal of the corticosteroid.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double amount to make up for a missed dose.
Additional Safety Advice
Apply a thin film of this medicine only to the affected area and gently rub it in. Wash your hands before and after application unless your hands are the treated area. Do not cover the area with tight bandages, plastic wrap, or diapers unless your doctor specifically instructs you to do so. Avoid contact with the eyes, mouth, and other mucous membranes. Do not use this medicine for longer than the prescribed duration, usually not more than two weeks. Do not use it on large areas of the body or on broken skin without medical advice. Keep this medicine out of reach of children. If you are pregnant, planning pregnancy, or breastfeeding, inform your doctor before using this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients have thinner skin and are more susceptible to corticosteroid side effects such as skin thinning, easy bruising, and adrenal suppression. Use the smallest effective amount for the shortest possible duration. Monitor for signs of systemic corticosteroid effects and consult a doctor regularly.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. Clotrimazole is generally considered acceptable for topical use during pregnancy when needed, but clobetasol should be used only if the potential benefit justifies the potential risk. Use the smallest amount for the shortest duration possible.
🏥 Post-Surgery Considerations
If you have recently had surgery, consult your doctor before applying this cream near the surgical site. Corticosteroids can delay wound healing and increase the risk of infection. Do not apply it to surgical wounds unless specifically directed by your surgeon.
🦷 Dental Procedures
This medicine is applied to the skin and is not expected to affect dental procedures. However, inform your dentist about all medicines you are using, including this cream, especially if you have been using it for a prolonged period.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can continue light exercise, but avoid activities that cause excessive sweating or friction on the treated area. Shower and dry the area thoroughly after exercise before reapplying the cream. Avoid swimming pools and communal showers until the infection clears to prevent spreading it to others.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied to the skin and does not usually affect your ability to drive or operate machinery. However, if you experience any dizziness or unusual tiredness, avoid driving until you feel well. You can continue your normal daily activities, but keep the treated area clean and dry, and avoid activities that cause excessive sweating.
🛑 When to Stop This Medicine
Stop using this medicine after completing the prescribed course or earlier if your doctor advises. Stop immediately and seek medical advice if you develop severe irritation, blistering, signs of a secondary infection, or any symptoms of systemic corticosteroid effects. Do not stop and restart the cream without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine can cause skin thinning, stretch marks, visible blood vessels, and increased hair growth. It can also lead to systemic corticosteroid effects such as adrenal suppression, high blood sugar, and Cushing's syndrome. Regular monitoring by a doctor is required if prolonged use is unavoidable. This medicine should generally not be used for more than two weeks without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For mild fungal infections without significant inflammation, a plain antifungal cream may be sufficient and avoids steroid side effects.
Evidence: Well-establishedFor extensive or resistant fungal infections, oral antifungal medicines may be prescribed by a doctor.
Evidence: Well-establishedKeeping the skin clean and dry helps prevent and manage fungal infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established for this topical medicine. However, if you are due for a vaccination, inform your doctor that you are using this cream, especially if you have been using it over a large area for a prolonged period.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate or freeze.
✅ DO
Keep the tube tightly closed when not in use.
❌ DON'T
Do not leave the cap off for long periods.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet where it may get damp.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not transfer to unmarked containers.
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case customs or security asks for it. Store it at room temperature and protect it from direct sunlight and extreme heat. If you are traveling across time zones, continue applying it at your usual times as closely as possible. Do not leave it in a hot car or checked luggage. If you are flying, keep it in your carry-on bag with your other medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice reduced itching and redness within a few days. The fungal infection usually clears within one to two weeks, but you must complete the prescribed course.
A: No, unless your doctor specifically tells you to. The face has thinner skin and is more prone to steroid side effects such as thinning and stretch marks.
A: This medicine is generally not recommended for children under 12 years unless prescribed by a pediatrician. Consult a doctor before using it on a child.
A: Apply it as soon as you remember if it is not almost time for your next dose. If it is, skip the missed dose and continue with your regular schedule. Do not double the amount.
A: No, you should complete the full prescribed course even if symptoms improve early. Stopping too soon can allow the infection to return.
🤔 Common Patient Concerns
🔄 Substitutes for clojohn-gm cream
View AllAlternative brands with exact same active ingredient:
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mixderm creamMDC Pharmaceuticals Pvt Ltd ₹21.68 32.1% CHEAPER
-
gracederm creamGlenmark Pharmaceuticals Ltd ₹39.67 24.3% COSTLIER
-
cortaz nc ointmentTorrent Pharmaceuticals Ltd ₹40.00 25.4% COSTLIER
-
ring-out plus creamMankind Pharma Ltd ₹46.88 46.9% COSTLIER
-
terbinaforce lite creamMankind Pharma Ltd ₹48.75 52.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: This medicine is only for specific fungal infections with inflammation. Using it for other rashes can worsen the condition. - Myth: More cream means faster healing.
Fact: Applying more than a thin film does not speed up healing and increases the risk of side effects. - Myth: It is safe to use this cream for months.
Fact: Prolonged use can thin the skin, cause stretch marks, and lead to systemic steroid effects. It should only be used for the prescribed short duration.
🔄 Alternative Options
Generic Alternatives
- Clotrimazole 1% + Clobetasol 0.05% cream (generic versions)
Brand Alternatives
- Clop-GM Neo Cream