CANDID TOTAL CREAM - Terbinafine (1% w/w) + Clobetasol (0.05% w/w) + Ofloxacin (0.75% w/w) medicine

CANDID TOTAL CREAM: Complete Medicine Guide

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🏭 Glenmark Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
🤰 Pregnancy Category Not established from the available information. The safe use of this medicine during pregnancy has not been established. It should be used only if the potential benefit justifies the potential risk to the fetus. Consult your doctor before using. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Evidence for the individual ingredients is well-established, but evidence for this specific fixed-dose combination is limited.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat, or difficulty breathing.
  • Signs of systemic steroid effects such as increased thirst, frequent urination, or high blood pressure.
  • Severe skin irritation, blistering, or peeling at the application site.
  • Signs of secondary infection such as increased redness, swelling, pain, or pus.
  • Yellowing of skin or eyes, or severe abdominal pain, which may indicate liver problems.
  • No improvement after completing the prescribed course.

If experiencing severe symptoms, call emergency services immediately.

What is CANDID TOTAL CREAM used for?

This medicine is a topical cream used to treat infected skin conditions caused by a mix of fungi, bacteria, and protozoa. It contains terbinafine, clobetasol, ofloxacin, and ornidazole. Apply a thin layer to the affected area as directed by your doctor, usually once or twice daily for up to two weeks.

  • Generic Name: Terbinafine (1% w/w) + Clobetasol (0.05% w/w) + Ofloxacin (0.75% w/w)
  • Manufacturer: Glenmark Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 CANDID TOTAL CREAM के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसका उपयोग त्वचा के संक्रमण के इलाज के लिए किया जाता है जो फंगस, बैक्टीरिया और प्रोटोजोआ के मिश्रण के कारण होता है। इसमें टर्बिनाफाइन, क्लोबेटासोल, ऑफलोक्सासिन और ओर्निडाजोल होते हैं। यह खुजली, लालिमा और सूजन को कम करने में मदद करती है। इसका उपयोग डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में लगाने की जगह पर जलन, खुजली, लालिमा या सूखापन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है। गंभीर एलर्जी प्रतिक्रिया दुर्लभ है लेकिन तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को केवल बाहरी उपयोग के लिए ही लगाएं। आंखों, मुंह और नाक से दूर रखें। प्रभावित क्षेत्र को साफ और सूखा करके पतली परत लगाएं। डॉक्टर के बताए समय से ज्यादा इस्तेमाल न करें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 CANDID TOTAL CREAM Uses & Benefits

[{"condition":"Infected dermatophytosis (ringworm, athlete's foot, jock itch)","description":"This medicine is used to treat fungal skin infections that have become secondarily infected with bacteria or protozoa, providing rapid relief from itching, redness, and inflammation" class="semantic-link" title="Medicines for swelling">swelling.","evidence":"Well-established for the combination in short-term use"},{"condition":"Infected eczema or dermatitis","description":"It helps reduce inflammation and itching while treating any bacterial or fungal infection present on the affected skin.","evidence":"Commonly used, but evidence for the combination is limited"},{"condition":"Infected intertrigo","description":"Used for skin fold infections that are complicated by mixed organisms, reducing inflammation and eradicating the infectious agents.","evidence":"Limited evidence, but widely used in practice"}]

Off-label uses: [{"condition":"Infected insect bites","description":"Sometimes prescribed off-label to prevent infection and reduce inflammation after insect bites.","evidence":"Limited"},{"condition":"Infected minor burns","description":"Rarely used off-label for superficial burns with signs of infection, but only under strict medical supervision.","evidence":"Limited"}]

Primary treatment for: Infected dermatophytosis (fungal skin infection with secondary bacterial or protozoal infection)

Also treats: Infected eczema, Infected dermatitis, Infected intertrigo

📋 Drug Information

Generic Name(s)Terbinafine (1% w/w) + Clobetasol (0.05% w/w) + Ofloxacin (0.75% w/w)
Brand NameCANDID TOTAL CREAM
ManufacturerGlenmark Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationTopical
StorageStore below 30°C in a dry place. Do not freeze. Keep the tube tightly closed. Protect from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin layer of the cream to the affected area and gently rub it in until it disappears.
2
Use this medicine exactly as prescribed, usually once or twice daily for up to two weeks.
3
Do not cover the treated area with bandages or dressings unless your doctor instructs you to.
4
Avoid using this cream on the face, groin, or underarms unless specifically directed by your doctor.
5
If your symptoms do not improve within a few days or worsen, contact your doctor promptly.
6
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Itchy, red, scaly skin patches
This medicine is commonly prescribed for infected fungal skin conditions.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
✅
Skin swelling and pain with pus
This medicine can treat bacterial skin infections.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTerbinafine, clobetasol, ofloxacin, and ornidazole can be absorbed through the skin when applied topically. The extent of absorption depends on the area treated, the condition of the skin, and whether an occlusive dressing is used. Clobetasol, being a potent steroid, can be absorbed in significant amounts if used on large areas or for prolonged periods. Not established from the available information for the other ingredients in this specific combination.
DistributionOnce absorbed, terbinafine is highly lipophilic and distributes into skin, fat, and other tissues. Clobetasol distributes into skin and systemic circulation. Ofloxacin and ornidazole distribute widely into body tissues and fluids. Not established from the available information for the exact distribution parameters of this combination.
Protein BindingTerbinafine is highly protein-bound (greater than 99%). Clobetasol is also highly protein-bound. Ofloxacin is about 20-30% protein-bound. Ornidazole is less than 15% protein-bound. Not established from the available information for the combination product.
MetabolismTerbinafine is extensively metabolized in the liver by cytochrome P450 enzymes. Clobetasol is metabolized in the liver. Ofloxacin is minimally metabolized. Ornidazole is metabolized in the liver. Not established from the available information for the topical combination.
Half-LifeTerbinafine has a terminal half-life of about 200 hours due to slow release from tissues. Clobetasol has a short half-life. Ofloxacin has a half-life of about 4-5 hours. Ornidazole has a half-life of about 12-14 hours. Not established from the available information for the combination product.
ExcretionTerbinafine and its metabolites are excreted mainly in urine. Clobetasol metabolites are excreted in urine and bile. Ofloxacin is excreted largely unchanged in urine. Ornidazole is excreted in urine and feces. Not established from the available information for the combination product.
BioavailabilityNot established from the available information for this topical combination. Systemic absorption varies with the site and condition of the skin.
Onset of ActionThe anti-inflammatory effect of clobetasol can be noticed within hours to a day. The antifungal and antibacterial effects begin immediately but visible improvement in infection usually takes a few days. Not established from the available information for exact onset times.
Peak Plasma TimeNot established from the available information for this topical combination.
Duration of ActionThe anti-inflammatory effect lasts for several hours after application. The antifungal and antibacterial effects persist as long as the medicine is present in the skin. Not established from the available information for exact duration.

How It Works

This medicine works through four different mechanisms. Terbinafine inhibits the fungal enzyme squalene epoxidase, which is needed for the synthesis of ergosterol, a key component of the fungal cell membrane. Without ergosterol, the fungal cell membrane becomes weak and the fungus dies. Clobetasol is a very potent corticosteroid that binds to glucocorticoid receptors inside cells, leading to suppression of inflammatory genes and reduction of redness, swelling, and itching. Ofloxacin is a fluoroquinolone antibiotic that blocks DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, thereby killing bacteria. Ornidazole is a nitroimidazole antiprotozoal that enters anaerobic organisms and generates reactive radicals that damage their DNA, leading to cell death. Together, these ingredients provide broad coverage against fungi, bacteria, and protozoa while rapidly controlling inflammation.

Mechanism Steps

1
Terbinafine inhibits fungal ergosterol synthesis: Terbinafine blocks squalene epoxidase, causing a deficiency of ergosterol and accumulation of squalene, which disrupts the fungal cell membrane and kills the fungus.
2
Clobetasol suppresses inflammation: Clobetasol binds to glucocorticoid receptors, enters the nucleus, and inhibits the production of inflammatory mediators like prostaglandins and leukotrienes, reducing redness, swelling, and itching.
3
Ofloxacin inhibits bacterial DNA replication: Ofloxacin blocks DNA gyrase and topoisomerase IV, preventing bacteria from replicating and causing bacterial cell death.
4
Ornidazole damages microbial DNA: Ornidazole is reduced by anaerobic organisms to reactive intermediates that break DNA strands, leading to death of protozoa and anaerobic bacteria.

💡 How to Take CANDID TOTAL CREAM

Strength: Cream containing terbinafine 1% w/w, clobetasol 0.05% w/w, ofloxacin 0.75% w/w, and ornidazole 2% w/w.

1Wash your hands before and after applying the cream.
2Clean and dry the affected area gently.
3Apply a thin layer of the cream to the affected skin.
4Gently rub it in until it disappears.
5Do not cover the area with a bandage unless instructed.
6Wash your hands after application unless your hands are the treated area.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area and gently rub it in, usually once or twice daily, or as directed by your doctor. The duration of treatment is typically 1 to 2 weeks, but it may vary depending on the condition and your response. Do not use more than the prescribed amount or for longer than recommended. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to the effects of topical corticosteroids, such as skin thinning. Use with caution and for the shortest duration necessary. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is required for topical use. However, if there is significant systemic absorption, caution is advised in patients with severe kidney disease. Consult your doctor.
Hepatic ImpairmentNo specific dose adjustment is required for topical use. However, if there is significant systemic absorption, caution is advised in patients with severe liver disease. Consult your doctor.
Maximum Daily DoseThe maximum daily dose depends on the area treated and the concentration. Do not exceed the prescribed frequency or duration. Typically, apply a thin layer once or twice daily. Not established from the available information for a specific maximum daily dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No specific food interactions
No restrictions
This medicine is applied to the skin and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of CANDID TOTAL CREAM

✅ Common Side Effects

Burning or stinging at application site (Common (1-10%))
This usually settles with continued use. If it persists or is severe, stop and consult your doctor.
Itching (Common (1-10%))
Avoid scratching. If itching worsens, consult your doctor.
Redness or dryness of skin (Common (1-10%))
Apply a gentle moisturizer if needed. If redness spreads, seek medical advice.
Skin thinning (Uncommon (0.1-1%))
Use only for the prescribed duration. Report any skin thinning to your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you have swelling of face, lips, throat, or difficulty breathing.
Systemic steroid effects (e.g., high blood sugar, high blood pressure) (Rare (<0.1%))
Contact your doctor if you notice increased thirst, frequent urination, or headaches.
Secondary infection (Rare (<0.1%))
If the treated area becomes more red, swollen, or painful, consult your doctor.

⚠️ Rare Side Effects

Cushing's syndrome (from prolonged use)
Report weight gain, moon face, or easy bruising to your doctor.
Skin atrophy and striae
Stop using and consult a dermatologist if you notice stretch marks or thinning skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Theophylline Moderate
Other topical steroids Major
Caffeine Moderate
Antacids Minor

🚨 Major Interactions

  • Other topical corticosteroids
  • Oral anticoagulants (e.g., warfarin)

⚡ Moderate Interactions

  • Theophylline
  • Caffeine

🍷 Alcohol Interaction

There is no known direct interaction between this topical medicine and alcohol. However, alcohol may worsen certain skin conditions or increase the risk of liver problems if the medicine is absorbed significantly. It is best to avoid excessive alcohol while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to terbinafine, clobetasol, ofloxacin, ornidazole, or any other ingredient.","Untreated bacterial, viral, or fungal skin infections that are not covered by the ingredients.","Acne vulgaris, rosacea, perioral dermatitis, and skin conditions around the mouth.","Use on the face, groin, or underarms unless directed by a doctor.","Children under 12 years of age, unless prescribed by a doctor."]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on large areas of the body or for longer than prescribed.","Do not cover with airtight dressings unless instructed.","If irritation or sensitization occurs, stop use and consult a doctor.","Use with caution in patients with liver or kidney disease.","Do not use for more than two weeks without medical advice.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether the ingredients in this medicine pass into breast milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is used by a nursing mother. Avoid applying to the breast area to prevent ingestion by the infant. Consult your doctor.

💊 Overdose Management

This medicine is for topical use. Overdose is unlikely. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, and abdominal pain. In case of excessive topical application, wash the area with plenty of water and consult a doctor if any unusual symptoms appear.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Always use this medicine exactly as your doctor has told you. Wash and dry the affected area gently before applying a thin layer of the cream. Do not cover the area with a bandage or dressing unless your doctor says so, as this can increase absorption and side effects. Avoid getting the cream in your eyes, nose, mouth, or other sensitive areas. If you accidentally get it in your eyes, rinse thoroughly with water. Do not use this medicine on large areas of the body, on broken skin, or for longer than the prescribed duration, usually not more than two weeks. Do not share this medicine with others, even if they have the same symptoms. Keep the tube tightly closed and out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, tell your doctor before using this medicine. Do not use other skin products on the same area without asking your doctor. If your symptoms do not improve within a few days or get worse, contact your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to skin thinning and systemic effects from topical steroids. Use this medicine with caution, for the shortest duration possible, and monitor for any signs of skin atrophy or systemic effects.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. The safe use of this medicine during pregnancy has not been established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before applying this medicine to the surgical area. It may interfere with wound healing or increase the risk of infection.

🦷 Dental Procedures

This medicine is for topical use on the skin and is not expected to affect dental procedures. However, inform your dentist if you are using it, especially if you have any allergies.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, clothing, or footwear with others.
😴
Wear loose, breathable clothing to reduce moisture.
💧
Avoid scratching the affected area to prevent spreading the infection.
🧘
Maintain good personal hygiene.
🌞
Follow a healthy diet to support your immune system.

🏋️ Exercise Considerations

You can continue exercising, but avoid activities that cause excessive sweating or friction on the treated area. Keep the area clean and dry after exercise. If the infection is on your feet, wear clean socks and change them daily.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Include probiotic foods like yogurt to support gut health.
Stay well hydrated.
Limit sugary and processed foods.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to work or drive. However, if you experience any skin irritation or allergic reaction, avoid driving or operating machinery until you feel better.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your symptoms do not improve within a few days, if they worsen, or if you experience any severe side effects. Do not stop abruptly if you have been using it for a long time; consult your doctor for a tapering plan.

📅 Long-Term Use Effects

Long-term use of this medicine, especially beyond two weeks, can lead to skin thinning, stretch marks, and increased absorption of the steroid, which may cause systemic effects like high blood sugar and high blood pressure. It is not meant for prolonged use. If you need treatment for more than two weeks, your doctor should reassess your condition.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Keep the skin clean and dry

Proper hygiene can help prevent and treat mild fungal infections.

Evidence: Well-established
Use of single-ingredient creams

Depending on the specific cause, a doctor may prescribe separate antifungal, antibiotic, or steroid creams.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccination, inform your doctor that you are using this medicine.

📦 Storage Guide

✅ DO

Store below 30°C in a dry place.

❌ DON'T

Do not freeze.

✅ DO

Keep the tube tightly closed.

❌ DON'T

Do not transfer to another container.

✅ DO

Protect from direct sunlight.

❌ DON'T

Do not store in the bathroom.

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label. Keep a copy of your prescription with you. Store it below 30°C and protect it from direct sunlight. If you are crossing time zones, continue applying as per your usual schedule. Declare it at customs if required. Do not leave it in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with athlete's foot that became infected and very itchy.
He was prescribed this medicine to apply twice daily. After three days, the itching and redness reduced significantly. He completed the full two-week course and the infection cleared. He learned to keep his feet dry and wear breathable footwear.
💡 Lesson: Consistent application and completing the full course are important to prevent recurrence.
👤 A 50-year-old woman with an infected eczema patch on her leg.
She used this medicine as directed for 10 days. The inflammation and infection improved, but she noticed her skin became a bit thin. Her doctor advised her to stop and use a moisturizer. The skin gradually recovered.
💡 Lesson: Prolonged use of potent steroid creams can thin the skin; always follow the prescribed duration.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start to feel relief from itching and redness within a few days. However, it is important to complete the full course as prescribed, even if symptoms improve.

Q: Can I stop using it once the symptoms go away?

A: No, you should complete the full prescribed course to ensure the infection is fully treated and to prevent recurrence.

Q: Is it safe to use on children?

A: This medicine is not recommended for children under 12 years unless prescribed by a doctor. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long can I use this medicine?
  • Is it safe for children?
  • Can I use it during pregnancy?
  • What if I miss a dose?
  • Does it interact with other medicines?

🛑 Myths vs. Facts

  • Myth: This cream can be used for any skin rash.
    Fact: This medicine is only for specific infected skin conditions. Using it for other rashes can worsen them or cause side effects.
  • Myth: More cream means faster healing.
    Fact: Applying more than prescribed increases the risk of side effects without speeding up healing.
  • Myth: It is safe to use for months.
    Fact: Prolonged use can cause skin thinning and other serious side effects. Use only for the prescribed duration.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Terbinafine + Clobetasol + Ofloxacin + Ornidazole","uses":"Infected fungal skin conditions","notes":"Combination product for mixed infections."},{"medicine":"Terbinafine cream","composition":"Terbinafine only","uses":"Fungal skin infections","notes":"No antibacterial or anti-inflammatory action."},{"medicine":"Clobetasol cream","composition":"Clobetasol only","uses":"Inflammation and itching","notes":"No antimicrobial action."}]

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