What is retoz-neo 120 tablet used for?

Etoricoxib 120 mg is a selective COX-2 inhibitor used for short-term relief of acute pain, such as after dental or orthopedic surgery, and for acute gout. It works by reducing inflammation and pain. It is not for minor aches and should be taken exactly as prescribed.

Generic Name: Etoricoxib (120mg)
Manufacturer: Dr Reddy's Laboratories Ltd
Form: Allopathy
Pregnancy Category: Consult doctor
Prescription Required: Yes

🇮🇳 retoz-neo 120 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एटोरिकॉक्सिब 120 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग मध्यम से गंभीर दर्द और सूजन के इलाज के लिए किया जाता है। यह मुख्य रूप से दांतों की सर्जरी, हड्डियों की सर्जरी, गाउट के दौरे, और गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस, एंकिलोजिंग स्पॉन्डिलाइटिस) में दर्द और सूजन को कम करने के लिए दी जाती है। यह दवा सीओएक्स-2 एंजाइम को रोककर काम करती है, जिससे दर्द पैदा करने वाले प्रोस्टाग्लैंडिन कम बनते हैं। यह केवल डॉक्टर के पर्चे पर मिलती है और डॉक्टर की सलाह के बिना नहीं लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, पेट दर्द, मतली, अपच, दस्त और रक्तचाप में वृद्धि शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, दिल का दौरा, स्ट्रोक, गुर्दे की समस्या और लीवर की समस्या शामिल हो सकती है। यदि आपको काला या खूनी मल, खून की उल्टी, सीने में दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा का पीला पड़ना दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब न लें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं जो आप ले रहे हैं। यदि आपको दिल, गुर्दे, लीवर या पेट की समस्या है तो डॉक्टर को बताएं। चक्कर आने पर वाहन न चलाएं।

💊 retoz-neo 120 tablet Uses & Benefits

[{"condition":"Acute pain after dental surgery","description":"This medicine is effective in relieving moderate to severe pain following tooth extraction or other dental procedures.","evidence":"Well-established"},{"condition":"Acute pain after orthopedic surgery","description":"Used for short-term management of pain after bone or joint surgery.","evidence":"Well-established"},{"condition":"Acute gouty arthritis","description":"Helps reduce pain and inflammation during acute gout attacks.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Provides symptomatic relief of pain and improves joint function in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Used to reduce pain and swelling in rheumatoid arthritis, often as part of a comprehensive treatment plan.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps relieve pain and stiffness in ankylosing spondylitis.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, though other NSAIDs are more commonly used.","evidence":"Limited"}]

Primary treatment for: Acute pain

Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute gouty arthritis

📋 Drug Information

Generic Name(s)	Etoricoxib (120mg)
Brand Name	retoz-neo 120 tablet
Manufacturer	Dr Reddy's Laboratories Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	NSAID's -Selective COX-2 Inhibitors
Route of Administration	Oral
Storage	Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container.
Shelf Life	24 months from the date of manufacture.
WHO Guideline	Not established from the available information.
ICMR Guideline	Not established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1

Take this medicine with food or milk to reduce stomach upset.

2

Use the lowest effective dose for the shortest duration possible.

3

Avoid alcohol while taking this medicine to prevent stomach bleeding.

4

Monitor your blood pressure regularly, especially if you have hypertension.

5

Report any signs of stomach bleeding, such as black stools or vomiting blood, immediately.

6

Do not take other NSAIDs or blood thinners without consulting your doctor.

7

Stay well hydrated throughout the day to support kidney function.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅

Chronic joint pain

This medicine is commonly prescribed for this.

Likely Use

❌

Fever

This medicine is not a primary fever reducer.

Not Primary

✅

Acute gout pain

This medicine is effective for acute gout attacks.

Likely Use

❌

Headache

This medicine is not typically used for tension headaches.

Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed after oral administration. The absolute bioavailability is approximately 100%. Food has no clinically significant effect on absorption.

DistributionThis medicine is highly bound to plasma proteins, primarily albumin. It distributes widely into body tissues. The volume of distribution at steady state is approximately 120 liters.

Protein BindingApproximately 92% bound to plasma proteins, mainly albumin.

MetabolismThis medicine is extensively metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP3A4. Several metabolites are formed, but they are not pharmacologically active.

Half-LifeThe elimination half-life is approximately 22 hours.

ExcretionThis medicine is excreted primarily in the urine (about 70%) and feces (about 20%), mostly as metabolites. Less than 1% is excreted unchanged.

BioavailabilityApproximately 100%.

Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.

Peak Plasma TimePeak plasma concentration is reached in about 1 hour after oral administration.

Duration of ActionThe analgesic effect lasts for approximately 24 hours, allowing for once-daily dosing.

How It Works

This medicine is a selective inhibitor of cyclooxygenase-2 (COX-2). It works by blocking the COX-2 enzyme, which is induced during inflammation and is responsible for producing prostaglandins that cause pain, swelling, and fever. By selectively inhibiting COX-2, it reduces pain and inflammation with less effect on COX-1, which is involved in protecting the stomach lining and maintaining normal platelet function. This selectivity is thought to reduce the risk of gastrointestinal ulcers compared to non-selective NSAIDs, but it may increase cardiovascular risks.

Mechanism Steps

1

Selective COX-2 binding: This medicine selectively binds to and inhibits the COX-2 enzyme, which is induced during inflammation.

2

Reduced prostaglandin synthesis: Inhibition of COX-2 decreases the production of prostaglandins, which are mediators of pain, inflammation, and fever.

3

Analgesic and anti-inflammatory effects: The reduction in prostaglandins leads to decreased pain perception and reduced swelling at the site of inflammation.

4

Minimal COX-1 inhibition: At therapeutic doses, this medicine does not significantly inhibit COX-1, which helps preserve gastric mucosal protection and platelet function.

💡 How to Take retoz-neo 120 tablet

Strength: Etoricoxib 120 mg immediate-release tablet.

1Take this medicine exactly as prescribed by your doctor.

2Swallow the tablet whole with a glass of water.

3Take with food or milk to reduce stomach upset.

4Do not crush, chew, or break the tablet.

5Take at the same time each day to maintain consistent levels.

6If you miss a dose, follow the missed dose instructions.

7Do not take more than the prescribed dose.

Dosage Information

Adult Dosage	The usual adult dose for acute pain is 120 mg once daily. For osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, the recommended dose is 60 mg or 90 mg once daily depending on the condition and response. The maximum recommended daily dose is 120 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric Dosage	Pediatric dosing is not established from available information. Consult a pediatrician.
Elderly Dosage	No specific dose adjustment is required for elderly patients, but use with caution due to increased risk of gastrointestinal and cardiovascular adverse effects. Monitor kidney function and blood pressure closely.
Renal Impairment	For patients with mild to moderate kidney impairment (creatinine clearance 30-60 mL/min), no dose adjustment is necessary. For severe kidney impairment (creatinine clearance <30 mL/min), use is contraindicated.
Hepatic Impairment	For patients with mild liver impairment (Child-Pugh A), no dose adjustment is necessary. For moderate liver impairment (Child-Pugh B), the recommended dose is 60 mg once daily. For severe liver impairment (Child-Pugh C), use is contraindicated.
Maximum Daily Dose	120 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food

Take with meals

Reduces stomach upset.

Grapefruit

Avoid

May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed

→ Take the missed dose as soon as you remember.

💡 Continue with the regular schedule.

📌 More than half the dosing interval has passed

→ Skip the missed dose.

💡 Do not double dose to catch up.

⚠️ Side Effects of retoz-neo 120 tablet

✅ Common Side Effects

Headache (Common (5-10%))

Usually resolves on its own. Consult your doctor if it persists or becomes severe.

Dizziness (Common (1-5%))

Avoid driving or operating machinery until you know how this medicine affects you.

Stomach pain (Common (1-5%))

Take with food or milk to reduce stomach upset. If pain is severe or persistent, consult your doctor.

Nausea (Common (1-5%))

Take with food. If nausea continues, talk to your doctor.

Indigestion (Common (1-5%))

Avoid spicy and fatty foods. Consult your doctor if it persists.

Diarrhea (Common (1-5%))

Stay hydrated. If diarrhea is severe or persistent, seek medical advice.

Elevated blood pressure (Common (1-5%))

Monitor your blood pressure regularly. Inform your doctor if it increases.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))

Seek immediate medical attention if you notice black or bloody stools, vomiting blood, or severe abdominal pain.

Heart attack (Rare (<0.1%))

Call emergency services if you experience chest pain, shortness of breath, or pain radiating to the arm or jaw.

Stroke (Rare (<0.1%))

Seek immediate medical help if you experience sudden weakness, numbness, confusion, trouble speaking, or vision changes.

Kidney failure (Rare (<0.1%))

Report decreased urine output, swelling in legs, or fatigue to your doctor immediately.

Liver toxicity (Rare (<0.1%))

Contact your doctor if you notice yellowing of skin or eyes, dark urine, or severe fatigue.

Severe allergic reaction (Rare (<0.1%))

Seek emergency care if you develop rash, itching, swelling of face or throat, or difficulty breathing.

⚠️ Rare Side Effects

Angioedema

Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat.

Stevens-Johnson syndrome

Seek emergency care if you develop a painful rash with blisters or peeling skin.

Aseptic meningitis

Report severe headache, stiff neck, fever, and sensitivity to light to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug	Severity	Effect
Warfarin	Major
ACE inhibitors	Major
Diuretics	Major
Lithium	Major
Methotrexate	Major
Corticosteroids	Moderate
SSRIs	Moderate
Aspirin	Moderate
Antacids	Minor
Rifampicin	Minor

🚨 Major Interactions

Warfarin
ACE inhibitors
Diuretics
Lithium
Methotrexate

⚡ Moderate Interactions

Corticosteroids
SSRIs
Aspirin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding and may worsen liver toxicity.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to etoricoxib or any component of the formulation","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe heart failure","Uncontrolled hypertension","Established ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease","Severe liver disease (Child-Pugh C)","Severe kidney disease (creatinine clearance

⚠️ Warnings & Precautions

["Cardiovascular risk: This medicine may increase the risk of serious cardiovascular thrombotic events. Use with caution in patients with cardiovascular risk factors.","Gastrointestinal risk: Can cause serious gastrointestinal adverse events, including bleeding, ulceration, and perforation. Use with caution in the elderly and in patients with a history of peptic ulcer disease.","Renal effects: May cause fluid retention and worsening of kidney function. Monitor kidney function in at-risk patients.","Hepatic effects: Can cause liver enzyme elevations. Monitor liver function in patients with liver disease.","Hypertension: May increase blood pressure. Monitor blood pressure regularly.","Allergic reactions: Serious allergic reactions have been reported. Discontinue if allergic reaction occurs.","Skin reactions: Serious skin reactions have been reported. Discontinue if rash or other signs of hypersensitivity occur.","Use in pregnancy: Avoid use, especially in the third trimester, due to risk of premature closure of the ductus arteriosus."]

🤱 Lactation Safety

Not established from the available information. It is not known if this medicine is excreted in human milk. Consult your doctor before breastfeeding.

💊 Overdose Management

There is no specific antidote for overdose. Management should be symptomatic and supportive. Gastric lavage may be considered if the overdose is recent. Monitor vital signs and provide supportive care. Contact a poison control center or emergency department immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not use this medicine if you are pregnant, especially after 30 weeks, or if you are breastfeeding without consulting your doctor. Inform your doctor about all other medicines you are taking, especially blood thinners, ACE inhibitors, diuretics, and other NSAIDs. If you have a history of heart disease, high blood pressure, kidney or liver problems, or stomach ulcers, your doctor may need to monitor you closely. Do not drive or operate heavy machinery if you feel dizzy. Store at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use with caution and monitor closely. The lowest effective dose should be used.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy, especially in the third trimester, as it may cause premature closure of the ductus arteriosus. If you are planning pregnancy, consult your doctor to discuss alternative treatments.

🏥 Post-Surgery Considerations

This medicine may be used for post-surgical pain, but it is contraindicated in patients undergoing coronary artery bypass graft (CABG) surgery. Consult your surgeon before taking this medicine after any surgery.

🦷 Dental Procedures

This medicine can be used for pain after dental procedures. Inform your dentist that you are taking this medicine before any dental work, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃

Maintain a healthy weight to reduce joint stress.

🥗

Regular low-impact exercise like swimming.

😴

Practice good posture.

💧

Include anti-inflammatory foods in your diet.

🧘

Get adequate sleep.

🌞

Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

While taking this medicine, you may experience dizziness or fatigue. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. Low-impact exercises like walking or swimming are generally safe.

🥗 Diet Recommendations

Include omega-3 rich foods

Reduce processed food intake

Stay well hydrated

Limit salt intake to manage blood pressure

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take breaks and stay hydrated.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects, seek medical advice immediately. Your doctor will determine when it is safe to stop based on your condition and response to treatment.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of cardiovascular events, gastrointestinal bleeding, and kidney problems. Regular monitoring of blood pressure, kidney function, and liver function is recommended. Use the lowest effective dose for the shortest duration possible.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established

Acupuncture

May help with pain relief in some patients.

Evidence: Limited

Weight management

Reduces stress on joints and improves symptoms.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store at room temperature and protect from moisture. If crossing time zones, consult your doctor about adjusting the dosing schedule. Keep it in your carry-on luggage to avoid loss. Check local customs regulations for prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain

Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.

💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.

👤 A 60-year-old man with acute gout attack

Was prescribed this medicine for severe gout pain. He experienced rapid relief within a few hours. He was advised to avoid alcohol and to monitor his kidney function.

💡 Lesson: This medicine can provide quick relief in acute gout, but monitoring for kidney and cardiovascular side effects is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects.

Q: How long can I take this medicine?

A: The duration of treatment depends on your condition. For acute pain, it is usually short-term. For chronic conditions, your doctor will determine the appropriate duration.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

Can I take this medicine long-term?
Will it affect my kidney function?
Can I drive after taking this medicine?
Does it interact with my blood pressure medicine?
What if I miss a dose?
Can I drink alcohol while taking this?

🔄 Substitutes for retoz-neo 120 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

Myth: Etoricoxib is a simple painkiller like paracetamol.
Fact: Etoricoxib is a potent prescription NSAID with significant cardiovascular and gastrointestinal risks. It should not be used without medical supervision.
Myth: Etoricoxib can be taken for any type of pain.
Fact: Etoricoxib is specifically for inflammatory pain and is not recommended for minor aches or fever.
Myth: Etoricoxib is safe for everyone.
Fact: Etoricoxib is contraindicated in people with certain heart, kidney, liver, or stomach conditions.

🔄 Alternative Options

Generic Alternatives

Etoricoxib 120 mg tablet (generic)

Brand Alternatives

Etoshine 120 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Etoricoxib","class":"Selective COX-2 inhibitor","half_life":"22 hours","common_use":"Acute pain, arthritis"},{"medicine":"Celecoxib","class":"Selective COX-2 inhibitor","half_life":"11 hours","common_use":"Arthritis, acute pain"},{"medicine":"Diclofenac","class":"Non-selective NSAID","half_life":"1-2 hours","common_use":"Arthritis, acute pain"},{"medicine":"Ibuprofen","class":"Non-selective NSAID","half_life":"2 hours","common_use":"Mild to moderate pain, fever"}]

Etoshine 120 Tablet (Etoricoxib 120mg): Complete Medicine Guide

When to Call Your Doctor IMMEDIATELY

What is retoz-neo 120 tablet used for?

🇮🇳 retoz-neo 120 tablet के बारे में (Hindi Summary)

💊 retoz-neo 120 tablet Uses & Benefits

📋 Drug Information

👨‍⚕️ Doctor's Practical Tips

🔍 Is This Medicine Right for Your Symptom?

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take retoz-neo 120 tablet

Dosage Information

Dosage Timeline

🍽️ Food Timing Guide

⏰ What to Do If You Miss a Dose

⚠️ Side Effects of retoz-neo 120 tablet

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

🍷 Alcohol Interaction

🔎 Check Your Other Medicines

🛡️ Safety & Warnings

🚫 Contraindications

⚠️ Warnings & Precautions

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

Additional Safety Advice

👴 Special Considerations for Elderly

💡 For Patients Above 65

🤰 Pregnancy Planning (TTC)

🏥 Post-Surgery Considerations

🦷 Dental Procedures

💚 Lifestyle Tips for Better Results

🏋️ Exercise Considerations

🥗 Diet Recommendations

💼 Impact on Daily Work & Life

🛑 When to Stop This Medicine

📅 Long-Term Use Effects

🌿 Non-Medicine Approaches

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

📦 Storage Guide

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✈️ Traveling with This Medicine

💰 Cost Analysis & Savings

👥 Real Patient Stories

💬 Questions Patients Often Ask

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

🔄 Substitutes for retoz-neo 120 tablet

🛑 Myths vs. Facts

🔄 Alternative Options

Generic Alternatives

Brand Alternatives

📊 Comparison with Similar Medicines

😊 Was this information helpful?

Browse Medicines A-Z

✍️ Write a Review

❓ Ask a Question

⚠️ Report an Issue