Adzole D 30mg/10mg Capsule SR: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or difficulty swallowing
- Chest pain, palpitations, or fainting
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes (jaundice)
- Uncontrolled vomiting or signs of dehydration
- Involuntary movements of face, tongue, or limbs
If experiencing severe symptoms, call emergency services immediately.
What is repepsa d 30mg/10mg capsule used for?
This medicine is a combination of Domperidone and Dexrabeprazole used to treat acid reflux, gastritis, and related symptoms. It works by reducing stomach acid and improving stomach emptying. It is usually taken once daily before breakfast.
- Generic Name: Domperidone (30mg) + Dexrabeprazole (10mg)
- Manufacturer: Akumentis Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 repepsa d 30mg/10mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन और डेक्सराबेप्राजोल का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, गैस्ट्र्रिटिस, अपच और मतली जैसी समस्याओं के इलाज के लिए किया जाता है। यह पेट में एसिड का उत्पादन कम करती है और पेट खाली होने की गति को बढ़ाती है। इसे आमतौर पर दिन में एक बार नाश्ते से पहले लिया जाता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुँह सूखना, सिरदर्द, दस्त, मतली, पेट दर्द और चक्कर आना शामिल हैं। कुछ लोगों में स्तन में दर्द या दूध का स्राव हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको दिल की धड़कन अनियमित लगे, गंभीर एलर्जी हो, या मुँह-चेहरे में सूजन आए तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कैप्सूल को चबाएं या तोड़ें नहीं, पूरा निगल लें। इसे खाली पेट, नाश्ते से 30 मिनट पहले लेना सबसे अच्छा है। इस दवा के साथ शराब न लें। जब तक आपको इसका असर पता न चले, वाहन न चलाएं। यदि आपको हृदय, यकृत या गुर्दे की बीमारी है तो डॉक्टर को बताएं। 8 सप्ताह से अधिक इसका उपयोग बिना डॉक्टर की सलाह के न करें।
💊 repepsa d 30mg/10mg capsule Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces acid reflux and heartburn by decreasing stomach acid production and improving stomach emptying.","evidence":"Well-established"},{"condition":"Non-ulcer dyspepsia","description":"Relieves symptoms like bloating, early satiety, and upper abdominal discomfort.","evidence":"Moderate"},{"condition":"Gastritis","description":"Helps reduce acid-related inflammation of the stomach lining.","evidence":"Moderate"},{"condition":"Nausea and vomiting associated with acid-related disorders","description":"Domperidone component helps control nausea and vomiting.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Diabetic gastroparesis","description":"Sometimes prescribed off-label to improve stomach emptying in diabetic patients.","evidence":"Limited"},{"condition":"Functional dyspepsia with reflux symptoms","description":"May be used off-label for symptom relief in functional dyspepsia.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Non-ulcer dyspepsia, Gastritis, Nausea and vomiting
📋 Drug Information
| Generic Name(s) | Domperidone (30mg) + Dexrabeprazole (10mg) |
| Brand Name | repepsa d 30mg/10mg capsule |
| Manufacturer | Akumentis Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Dexrabeprazole is a proton pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase enzyme in the stomach's parietal cells, suppressing both basal and stimulated acid secretion. Domperidone is a peripheral dopamine D2 receptor antagonist that enhances gastric motility and accelerates gastric emptying without crossing the blood-brain barrier significantly. Together, they reduce acid exposure and improve stomach emptying, providing relief from reflux and dyspeptic symptoms.
Mechanism Steps
💡 How to Take repepsa d 30mg/10mg capsule
Strength: Capsule containing Domperidone 30 mg and Dexrabeprazole 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule taken orally once daily on an empty stomach, at least 30 minutes before breakfast, or as directed by your doctor. The dose may be adjusted based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially cardiac effects and drowsiness. Use with caution and monitor closely. Dose adjustment may be needed based on renal and hepatic function. |
| Renal Impairment | In patients with severe renal impairment (creatinine clearance <30 mL/min), domperidone should be used with caution and dose reduction may be necessary. Dexrabeprazole does not require dose adjustment in renal impairment. Consult your doctor. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no dose adjustment is needed for dexrabeprazole. However, domperidone should be used with caution. In severe hepatic impairment, this medicine is contraindicated. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (Domperidone 30 mg + Dexrabeprazole 10 mg) per day. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of repepsa d 30mg/10mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Atazanavir | Major | |
| Methotrexate | Major | |
| Amiodarone | Major | |
| Clopidogrel | Moderate | |
| Warfarin | Moderate | |
| Digoxin | Moderate | |
| Anticholinergics | Moderate | |
| Antacids | Minor | |
| Sucralfate | Minor |
🚨 Major Interactions
- Ketoconazole, itraconazole
- Atazanavir, nelfinavir
- Methotrexate
- QT-prolonging drugs (e.g., amiodarone, sotalol)
⚡ Moderate Interactions
- Clopidogrel
- Warfarin
- Digoxin
- Anticholinergic drugs
🍷 Alcohol Interaction
Alcohol may worsen stomach irritation and increase the risk of drowsiness and dizziness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to domperidone, dexrabeprazole, or any component of the formulation","Gastrointestinal bleeding, mechanical obstruction, or perforation","Prolactin-releasing pituitary tumor (prolactinoma)","Severe hepatic impairment","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disease or electrolyte imbalances.","Avoid in patients with known QT prolongation or family history of sudden cardiac death.","May cause drowsiness; avoid driving or operating machinery until effects are known.","Do not use for more than 8 weeks without medical review.","May increase risk of bone fractures with long-term use.","May cause low magnesium levels with prolonged use; monitor if needed.","Inform your doctor if you have liver or kidney disease.","Not recommended for children unless prescribed by a pediatrician."]
🤱 Lactation Safety
Domperidone passes into breast milk and may cause side effects in the infant. Dexrabeprazole may also pass into breast milk. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause severe drowsiness, irregular heartbeat, and extrapyramidal symptoms. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1 hour of ingestion. Monitor ECG and vital signs.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the capsule; swallow it whole. It is best taken on an empty stomach, at least 30 minutes before breakfast, unless your doctor advises otherwise. Avoid alcohol while taking this medicine as it may worsen stomach irritation and increase drowsiness. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have heart problems, liver disease, kidney disease, or electrolyte imbalances. Do not use this medicine for more than 8 weeks without medical review. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to side effects like drowsiness, dizziness, and cardiac arrhythmias. Use with caution and monitor renal and hepatic function. Dose adjustment may be necessary.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. It should be used only if clearly needed. Discuss alternative treatments if necessary.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if prescribed by your surgeon. It may affect gastric motility and acid secretion, which could impact recovery. Inform your surgeon about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may increase the risk of bleeding during dental procedures due to potential interactions with anticoagulants. Your dentist may need to adjust your treatment plan.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid vigorous exercise immediately after meals as it may worsen reflux. Light walking after meals can aid digestion. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause frequent urination or diarrhea, which can affect work. Plan your dose timing to minimize impact.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or no improvement after the prescribed course, contact your doctor. Abrupt discontinuation may cause rebound acid hypersecretion.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to low magnesium levels, increased risk of bone fractures, and vitamin B12 deficiency. Domperidone may cause hyperprolactinemia with prolonged use. Regular monitoring and periodic review by a doctor are recommended. Do not use for more than 8 weeks without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet changes, weight loss, and elevating the head of the bed can reduce reflux symptoms.
Evidence: Well-establishedH2 blockers or other PPIs may be alternatives if this combination is not suitable.
Evidence: Well-establishedIf acid suppression is not needed, domperidone alone may be used.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about adjusting the timing. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Dexrabeprazole starts reducing acid within 1 hour, and domperidone improves motility within 30-60 minutes. Symptom relief may take a few days.
A: It is best taken on an empty stomach, 30 minutes before breakfast. Food may delay domperidone absorption.
A: If less than 12 hours have passed, take it as soon as you remember. If more than 12 hours, skip it and continue with your regular schedule. Do not double dose.
A: Consult your doctor. It is not recommended unless clearly needed.
A: Do not stop without consulting your doctor, as symptoms may rebound.
🤔 Common Patient Concerns
🔄 Substitutes for repepsa d 30mg/10mg capsule
View AllAlternative brands with exact same active ingredient:
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dirab d 30mg/10mg capsule srHetero Drugs Ltd ₹37.41 65% CHEAPER
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ralio d 30mg/10mg capsuleDWD Pharmaceuticals Ltd ₹48.57 54.6% CHEAPER
-
dexrobel-dsr capsuleAamorb Pharmaceuticals Pvt Ltd ₹79.50 25.6% CHEAPER
-
emrab d capsule 30 mg/10 mgEmcure Pharmaceuticals Ltd ₹85.08 20.4% CHEAPER
-
rabidex dsr capsuleNexure Lifesciences Pvt Ltd ₹91.88 14% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for immediate relief of heartburn.
Fact: This medicine is not for immediate relief; it takes time to reduce acid production and improve motility. - Myth: It is safe to take this medicine indefinitely.
Fact: Long-term use should be under medical supervision due to potential side effects. - Myth: This medicine can be taken with alcohol without any issues.
Fact: Alcohol may worsen side effects and should be avoided.
🔄 Alternative Options
Generic Alternatives
- Domperidone + Dexrabeprazole capsule