Mifepristone 200 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Heavy vaginal bleeding that soaks more than two sanitary pads per hour for two hours.
- Severe abdominal pain that does not go away or gets worse.
- Fever above 100.4°F (38°C) with chills or foul-smelling discharge.
- Feeling very dizzy, weak, or fainting.
- Chest pain, difficulty breathing, or a very fast heartbeat.
- Swelling of the face, lips, tongue, or throat.
- Yellowing of the skin or eyes.
- Passing large blood clots or tissue.
- No bleeding within 24 hours of taking misoprostol.
- Persistent nausea, vomiting, or diarrhea leading to dehydration.
If experiencing severe symptoms, call emergency services immediately.
What is Relezed 200mg Tablet used for?
This medicine contains Mifepristone 200 mg, an antiprogestin tablet used under medical supervision to terminate an early intrauterine pregnancy, usually with misoprostol. It blocks progesterone, causing the uterine lining to break down and the pregnancy to detach. It is also used for Cushing's syndrome. It must never be taken without a doctor's supervision because it can cause serious bleeding and other complications.
- Generic Name: Mifepristone (200mg)
- Manufacturer: Zee Laboratories
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Relezed 200mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मिफेप्रिस्टोन 200 मिलीग्राम की एक टैबलेट है, जिसका उपयोग डॉक्टर की देखरेख में शुरुआती गर्भावस्था को समाप्त करने के लिए किया जाता है। यह आमतौर पर मिसोप्रोस्टोल के साथ मिलकर काम करती है। यह दवा प्रोजेस्टेरोन हार्मोन को रोककर गर्भाशय की परत को तोड़ती है और गर्भावस्था को समाप्त करने में मदद करती है। इसका उपयोग कुशिंग सिंड्रोम में भी किया जा सकता है। यह दवा बिना डॉक्टर की सलाह के कभी नहीं लेनी चाहिए क्योंकि इससे गंभीर रक्तस्राव और अन्य जटिलताएं हो सकती हैं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट में ऐंठन, योनि से रक्तस्राव, मतली, उल्टी, दस्त, सिरदर्द, चक्कर आना और थकान शामिल हैं। गंभीर दुष्प्रभावों में भारी रक्तस्राव, अधूरा गर्भपात, गर्भाशय में संक्रमण और गंभीर एलर्जी प्रतिक्रिया शामिल हैं। अगर आपको बहुत अधिक रक्तस्राव, तेज बुखार, ठंड लगना, बदबूदार स्राव या तेज दर्द हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: यह दवा केवल योग्य डॉक्टर की देखरेख में ही लेनी चाहिए। बिना डॉक्टर की सलाह के इसका सेवन न करें। दवा लेने से पहले यह सुनिश्चित करें कि गर्भावस्था गर्भाशय में है और निर्धारित समय सीमा के भीतर है। आपातकालीन चिकित्सा सुविधा उपलब्ध होनी चाहिए। शराब और दर्द निवारक दवाओं से बचें। डॉक्टर के बताए अनुसार फॉलो-अप कराएं। अगर भारी रक्तस्राव, तेज दर्द, बुखार या अस्वस्थता महसूस हो तो तुरंत अस्पताल जाएं।
💊 Relezed 200mg Tablet Uses & Benefits
- [{"condition":"Medical termination of early intrauterine pregnancy","description":"This medicine is used together with misoprostol to end a pregnancy up to 70 days or 10 weeks of gestation.
- It is approved for this purpose in many countries and must be used under medical supervision.","evidence":"Well-established"},{"condition":"Cushing's syndrome","description":"This medicine can be used to treat endogenous Cushing's syndrome in adults who are not suitable for surgery or in whom surgery has not been curative.
- It works by blocking the effects of cortisol at the receptor level.","evidence":"Established for specific indications"},{"condition":"Uterine fibroids","description":"This medicine may be used to reduce the size of uterine fibroids before surgery or to manage symptoms in selected patients.
- It is not a first-line treatment for all patients.","evidence":"Limited to specific clinical settings"}]
Off-label uses: [{"condition":"Emergency contraception","description":"This medicine has been studied for emergency contraception, but it is not approved for this use in many countries and is not a standard option.","evidence":"Limited"},{"condition":"Endometriosis","description":"This medicine has been explored for the treatment of endometriosis-related pain, but evidence is limited and it is not a routine treatment.","evidence":"Limited"},{"condition":"Psychotic depression","description":"This medicine has been studied as an add-on treatment for psychotic depression in some research settings, but this is not a standard approved use.","evidence":"Investigational"}]
Primary treatment for: Early intrauterine pregnancy termination
Also treats: Cushing's syndrome, Uterine fibroids
📋 Drug Information
| Generic Name(s) | Mifepristone (200mg) |
| Brand Name | Relezed 200mg Tablet |
| Manufacturer | Zee Laboratories |
| Packaging / Form | strip of 1 Tablet (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep away from direct sunlight and moisture. Store in the original container and keep out of reach of children. |
| Shelf Life | The shelf life is usually 24 to 36 months from the date of manufacture. Check the expiry date on the pack before use. Do not use after the expiry date. |
| WHO Guideline | The World Health Organization includes Mifepristone in combination with misoprostol in its essential medicines list for medical termination of pregnancy. It recommends use under proper medical supervision and with access to emergency care. |
| ICMR Guideline | The Indian Council of Medical Research has guidelines for medical termination of pregnancy that include the use of Mifepristone followed by misoprostol. These guidelines emphasize the need for medical supervision, confirmation of intrauterine pregnancy, and follow-up care. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding with high affinity to the progesterone receptor and blocking the effects of progesterone. Progesterone is needed to maintain the lining of the uterus and to keep a pregnancy going. By blocking this hormone, the medicine causes the uterine lining to break down and makes the uterus more sensitive to prostaglandins, which leads to cervical softening and uterine contractions. When used with misoprostol, this medicine helps the uterus to expel the pregnancy tissue. In Cushing's syndrome, the same blocking action at the glucocorticoid receptor reduces the effects of excess cortisol.
Mechanism Steps
💡 How to Take Relezed 200mg Tablet
Strength: Mifepristone 200 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The dose of this medicine is determined by your doctor based on the condition being treated. For medical termination of early pregnancy, a single 200 mg tablet is usually taken orally under medical supervision, followed by misoprostol 24 to 48 hours later as prescribed. For Cushing's syndrome, the dose is individualized and may range from 300 mg to 1200 mg daily, depending on response and tolerability. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never self-medicate or change the dose without your doctor's advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | This medicine is not typically used for termination of pregnancy in elderly women. For other conditions such as Cushing's syndrome, the dose is individualized by a clinician based on kidney and liver function, and other medicines being taken. Elderly patients may be more sensitive to side effects and should be monitored closely. |
| Renal Impairment | No specific dose adjustment is established for people with kidney disease. However, this medicine should be used with caution in severe kidney impairment. Your doctor will decide if the dose needs to be adjusted based on your kidney function. |
| Hepatic Impairment | This medicine is broken down in the liver. People with severe liver disease may have higher levels of the medicine in the blood. Your doctor may adjust the dose or avoid this medicine if you have severe liver impairment. Regular monitoring of liver function may be needed. |
| Maximum Daily Dose | The maximum daily dose depends on the condition being treated. For termination of pregnancy, a single 200 mg dose is used. For Cushing's syndrome, the maximum dose is usually 1200 mg per day, but this must be determined by a qualified clinician. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Relezed 200mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Misoprostol | Major | |
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Warfarin | Major | |
| Ibuprofen | Major | |
| Dexamethasone | Moderate | |
| Oral contraceptives | Moderate | |
| Grapefruit juice | Moderate | |
| Paracetamol | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Misoprostol
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, ritonavir)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin, St. John's wort)
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Warfarin and other anticoagulants
⚡ Moderate Interactions
- Corticosteroids
- Oral contraceptives
- Grapefruit juice
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase the risk of stomach bleeding, worsen dizziness, and may affect how your body handles the medicine. It can also make it harder to judge how you are feeling after the procedure.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Confirmed or suspected ectopic pregnancy.","Intrauterine device (IUD) in place. It must be removed before treatment.","Chronic adrenal failure or adrenal insufficiency.","Known allergy to Mifepristone or any ingredient in the tablet.","Inherited porphyria.","Bleeding disorders or current anticoagulant therapy.","Severe asthma uncontrolled by treatment.","Pregnancy beyond 70 days or 10 weeks of gestation for termination use.","Undiagnosed adnexal mass or unexplained pelvic pain."]
⚠️ Warnings & Precautions
["This medicine must only be taken under the supervision of a qualified healthcare professional.","Confirm the pregnancy is intrauterine and within the approved gestational age before taking this medicine.","Ensure access to emergency medical care and blood transfusion if needed.","Do not take this medicine if you have an intrauterine device in place. It must be removed first.","Avoid alcohol and NSAIDs during treatment.","Use effective contraception after the procedure to prevent another pregnancy.","Follow up with your doctor as scheduled to confirm the termination is complete.","Seek immediate medical help if you have heavy bleeding, severe pain, fever, or feel very unwell.","This medicine may cause dizziness. Avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have liver or kidney disease, or if you take other medicines."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally recommended to avoid breastfeeding for a short period after taking this medicine. Discuss with your doctor about the safest way to feed your baby during treatment.
💊 Overdose Management
There is no specific antidote for an overdose of this medicine. If you take too much, seek emergency medical care immediately. Treatment is supportive and may include monitoring of vital signs, management of bleeding, and treatment of any allergic reactions. Do not try to vomit unless told to do so by a healthcare professional.
⏰ Missed Dose
This medicine is usually taken as a single dose or as part of a specific treatment schedule. If you miss a dose, contact your doctor or clinic immediately for instructions. Do not take a double dose to make up for a missed one. The timing of this medicine is important for its effectiveness, so follow your doctor's schedule exactly.
Additional Safety Advice
This medicine must only be taken under the direct supervision of a qualified healthcare professional who is trained in medical abortion care. Never self-medicate or obtain this medicine without a prescription. Before taking this medicine, confirm the pregnancy is intrauterine and within the approved gestational age. Ensure that emergency medical care and blood transfusion facilities are available nearby. Do not take this medicine if you have an ectopic pregnancy, an intrauterine device in place, adrenal insufficiency, or a bleeding disorder. Avoid alcohol and nonsteroidal anti-inflammatory drugs unless specifically approved by your doctor. Follow up with your doctor as scheduled to confirm that the termination is complete. Use effective contraception after the procedure to prevent unintended pregnancy. If you experience heavy bleeding, severe pain, fever, or feel unwell, seek emergency care immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not typically used for termination of pregnancy in elderly women. For conditions like Cushing's syndrome, elderly patients may be more sensitive to side effects and should be monitored closely. Dose adjustments may be needed based on kidney and liver function.
🤰 Pregnancy Planning (TTC)
This medicine is used to terminate a pregnancy. If you are planning a pregnancy, do not take this medicine. If you have taken this medicine and wish to become pregnant, wait until you have had a follow-up and your doctor confirms you are ready. Use effective contraception until you are ready to conceive.
🏥 Post-Surgery Considerations
If you have had surgery, inform your surgeon and anesthesiologist that you are taking or have taken this medicine. It may affect bleeding and healing. Your doctor will advise you on when it is safe to take this medicine after surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may increase the risk of bleeding. Your dentist may recommend postponing non-urgent dental work until you have completed treatment and recovered.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise, heavy lifting, and intense physical activity until bleeding and cramping have settled. Light walking is usually fine. Ask your doctor when you can return to your normal exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, fatigue, and cramping. Avoid driving or operating heavy machinery until you know how it affects you. You may need to take time off work or school during the treatment and recovery period. Discuss with your doctor about when you can return to your normal activities.
🛑 When to Stop This Medicine
Do not stop this medicine without talking to your doctor. If you are using it for termination of pregnancy, the treatment is usually a single dose followed by misoprostol. If you are using it for Cushing's syndrome, your doctor will decide when to stop based on your response and monitoring. Seek emergency care if you have severe bleeding, pain, fever, or other red-flag symptoms.
📅 Long-Term Use Effects
There are no known long-term effects of this medicine on fertility or general health when used as prescribed. However, repeated use for termination of pregnancy without addressing contraception can lead to repeated procedures and their risks. For Cushing's syndrome, long-term use requires regular monitoring of liver function, blood sugar, and cortisol levels. Always follow up with your doctor for ongoing care.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A procedure performed by a doctor to end a pregnancy. It may be an option depending on the stage of pregnancy and your medical situation.
Evidence: Well-establishedMisoprostol can be used alone for termination of pregnancy, but it is less effective than the combination with Mifepristone.
Evidence: Established but less effectiveWaiting for the pregnancy to pass naturally. This is only suitable in specific situations and under medical supervision.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, if you need a vaccine, inform your doctor that you are taking this medicine. Routine vaccinations can usually be given, but timing may depend on your overall health.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container with the label intact.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
If you need to travel while taking this medicine, carry it in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a letter from your doctor explaining the medical reason for the medicine. Check the laws of your destination country regarding this medicine, as some countries have strict regulations. Store the tablet at room temperature and protect it from extreme heat or cold. If you are traveling across time zones, follow your doctor's instructions about timing. Always keep emergency contact numbers for a local doctor or hospital.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effects usually begin within 24 to 48 hours after taking this medicine. Bleeding and cramping typically start after the follow-up dose of misoprostol, which is taken 24 to 48 hours later.
A: Contact your doctor or clinic immediately for instructions. Do not take a double dose. The timing of this medicine is important for its effectiveness.
A: No. This medicine must only be taken under the supervision of a qualified healthcare professional. It can cause serious bleeding and other complications that require emergency care.
A: There is no evidence that this medicine causes permanent infertility. Fertility usually returns quickly after the treatment.
A: This medicine passes into breast milk in small amounts. It is generally recommended to avoid breastfeeding for a short period after taking it. Discuss with your doctor about the safest way to feed your baby.
🤔 Common Patient Concerns
🔄 Substitutes for Relezed 200mg Tablet
View AllAlternative brands with exact same active ingredient:
-
medabon 200mg tabletSun Pharmaceutical Industries Ltd ₹20.25 74.6% CHEAPER
-
pregnot 200mg tabletLupin Ltd ₹46.88 41.2% CHEAPER
-
mifecon 200mg tabletSun Pharmaceutical Industries Ltd ₹59.77 25% CHEAPER
-
termipil 200mg kitAlkem Laboratories Ltd ₹60.00 24.7% CHEAPER
-
pregnot kit 200mg tabletLupin Ltd ₹123.05 54.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Mifepristone can be taken safely without medical supervision.
Fact: This medicine must only be taken under the care of a qualified healthcare professional. It can cause serious bleeding and other complications that require emergency care. - Myth: Mifepristone alone is enough to end a pregnancy.
Fact: Mifepristone is usually used together with misoprostol to complete the termination. Taking it alone may not be effective. - Myth: Mifepristone causes infertility.
Fact: There is no evidence that Mifepristone causes permanent infertility. Fertility usually returns quickly after the treatment. - Myth: Mifepristone is an abortion pill that works immediately.
Fact: It takes time for the medicine to work. Bleeding and cramping usually start within 24 to 48 hours, and the full effect occurs after misoprostol.
🔄 Alternative Options
Generic Alternatives
- Mifepristone 200 mg tablet
Brand Alternatives
- Mifegest
- Mifeprex
- Korlym