Bytey Total 30mg/15mg/500mg Tablet SR: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Severe hypoglycemia: confusion, seizures, loss of consciousness, or inability to take sugar by mouth.
- Signs of heart failure: rapid weight gain, swelling in the legs, shortness of breath, or fatigue.
- Signs of liver injury: yellowing of skin or eyes, dark urine, persistent nausea, or abdominal pain.
- Signs of bladder cancer: blood in urine or painful urination.
- Severe allergic reaction: rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing.
- Severe abdominal pain that may radiate to the back, with or without nausea and vomiting (possible pancreatitis).
- Sudden vision changes or blurred vision.
If experiencing severe symptoms, call emergency services immediately.
What is reclimet-pg 30 tablet sr used for?
This medicine is a combination of Gliclazide 30 mg and Pioglitazone 15 mg used to treat type 2 diabetes. It works by increasing insulin secretion and improving insulin sensitivity. It is taken once daily with the first main meal. It can cause low blood sugar, weight gain, and swelling. Regular monitoring is required.
- Generic Name: Gliclazide (30mg) + Pioglitazone (15mg)
- Manufacturer: Dr Reddy's Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 reclimet-pg 30 tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा ग्लाइक्लाजाइड 30 मिलीग्राम और पियोग्लिटाज़ोन 15 मिलीग्राम का संयोजन है, जिसका उपयोग टाइप 2 मधुमेह (डायबिटीज) में रक्त शर्करा को नियंत्रित करने के लिए किया जाता है। यह उन वयस्कों के लिए है जिनका रक्त शर्करा आहार, व्यायाम और एक दवा से नियंत्रित नहीं हो पाता। यह दवा अग्न्याशय से इंसुलिन निकालने में मदद करती है और शरीर की इंसुलिन के प्रति संवेदनशीलता को बढ़ाती है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कम रक्त शर्करा (हाइपोग्लाइसीमिया), वजन बढ़ना, मतली, दस्त, सिरदर्द, और पैरों में सूजन शामिल हैं। गंभीर दुष्प्रभावों में गंभीर हाइपोग्लाइसीमिया, दिल की विफलता, लीवर की क्षति, मूत्राशय का कैंसर, और हड्डियों का फ्रैक्चर शामिल हो सकते हैं। यदि आपको चक्कर आना, पसीना आना, कमजोरी, पैरों में सूजन, सांस लेने में कठिनाई, या पेशाब में खून दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। इसे दिन के पहले मुख्य भोजन के साथ लें ताकि कम रक्त शर्करा का खतरा कम हो। अपने साथ हमेशा ग्लूकोज की गोलियां या मिठाई रखें। नियमित रूप से रक्त शर्करा की जांच करें। शराब का सेवन न करें या सीमित करें। यदि आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं तो डॉक्टर को बताएं। इस दवा को बच्चों की पहुंच से दूर रखें।
💊 reclimet-pg 30 tablet sr Uses & Benefits
[{"condition":"Type 2 diabetes mellitus","description":"Used as an add-on therapy to improve glycemic control in adults whose blood sugar is not adequately controlled with diet, exercise, and a single oral antidiabetic agent.","evidence":"Well-established"},{"condition":"Insulin resistance in type 2 diabetes","description":"Pioglitazone component improves insulin sensitivity, while gliclazide increases insulin secretion, addressing two core defects in type 2 diabetes.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Polycystic ovary syndrome (PCOS)","description":"Pioglitazone has been studied off-label for insulin resistance in PCOS, but this combination is not approved for this use.","evidence":"Limited"},{"condition":"Non-alcoholic fatty liver disease (NAFLD)","description":"Pioglitazone has shown some benefit in NAFLD in research settings, but this combination is not indicated for this purpose.","evidence":"Limited"}]
Primary treatment for: Type 2 diabetes mellitus
Also treats: Insulin resistance, Dyslipidemia, Obesity
📋 Drug Information
| Generic Name(s) | Gliclazide (30mg) + Pioglitazone (15mg) |
| Brand Name | reclimet-pg 30 tablet sr |
| Manufacturer | Dr Reddy's Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. The World Health Organization does not specifically recommend this fixed-dose combination. Treatment guidelines for type 2 diabetes should be followed as per local standards. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research (ICMR) guidelines for type 2 diabetes management should be consulted for specific recommendations. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two oral antidiabetic agents with complementary mechanisms. Gliclazide, a second-generation sulfonylurea, binds to ATP-sensitive potassium channels on pancreatic beta cells, causing depolarization and increased calcium influx, which triggers insulin release. Pioglitazone, a thiazolidinedione, activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), leading to increased transcription of insulin-responsive genes. This enhances insulin sensitivity in peripheral tissues such as skeletal muscle and adipose tissue, and reduces hepatic glucose output. The combined effect lowers fasting and postprandial blood glucose levels.
Mechanism Steps
💡 How to Take reclimet-pg 30 tablet sr
Strength: Tablet containing Gliclazide 30 mg and Pioglitazone 15 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily with the first main meal of the day. The dose may be adjusted by your doctor based on your blood sugar levels, kidney and liver function, and other medicines you are taking. Do not change the dose without consulting your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially the risk of hypoglycemia. The dose should be selected with caution, usually starting at the lower end of the dosing range. Regular monitoring of blood glucose, kidney function, and heart function is recommended. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Gliclazide dose may need to be reduced in patients with mild to moderate renal impairment. This medicine is not recommended in severe renal impairment (eGFR < 30 mL/min). Pioglitazone does not require dose adjustment in renal impairment, but caution is advised. Consult your doctor for dose adjustment. |
| Hepatic Impairment | This medicine is contraindicated in patients with severe liver disease. In mild to moderate hepatic impairment, dose reduction or alternative therapy may be necessary. Liver function should be monitored regularly. Consult your doctor for dose adjustment. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is one tablet (Gliclazide 30 mg + Pioglitazone 15 mg) once daily. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of reclimet-pg 30 tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | |
| Beta-blockers | Major | |
| Fluconazole | Major | |
| Gemfibrozil | Major | |
| Rifampicin | Major | |
| Corticosteroids | Moderate | |
| Thiazide diuretics | Moderate | |
| ACE inhibitors | Moderate | |
| Alcohol | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Insulin or other oral antidiabetic agents
- Beta-blockers
- CYP2C9 inhibitors (e.g., fluconazole, miconazole)
- CYP2C8 inhibitors (e.g., gemfibrozil)
- Rifampicin
⚡ Moderate Interactions
- Corticosteroids
- Thiazide diuretics
- ACE inhibitors
- Alcohol
- MAO inhibitors
🍷 Alcohol Interaction
Alcohol can increase the risk of hypoglycemia when taken with this medicine. It can also worsen liver function and increase the risk of lactic acidosis. It is advisable to avoid alcohol or limit intake to occasional small amounts, and always consult your doctor about safe limits.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe liver disease or active liver disease","Severe kidney impairment (eGFR < 30 mL/min)","Symptomatic heart failure","Known hypersensitivity to gliclazide, pioglitazone, or any component","Pregnancy and breastfeeding","Bladder cancer or history of bladder cancer","Use of strong CYP2C8 inhibitors (e.g., gemfibrozil)"]
⚠️ Warnings & Precautions
["May cause hypoglycemia, especially when combined with other antidiabetic agents, alcohol, or during missed meals. Educate patients on recognition and management.","Pioglitazone can cause fluid retention and precipitate heart failure. Monitor for signs and symptoms.","Rare cases of liver injury have been reported. Monitor liver function tests.","Pioglitazone may increase the risk of bladder cancer. Report any blood in urine or urinary symptoms.","May increase the risk of bone fractures, especially in women. Ensure adequate calcium and vitamin D.","Weight gain is common. Encourage lifestyle modifications.","May cause macular edema. Regular eye exams are recommended.","Do not use in patients with active bladder cancer or a history of bladder cancer.","Use with caution in elderly patients due to increased risk of hypoglycemia and heart failure.","Not recommended for use in children."]
🤱 Lactation Safety
Not established from the available information. It is not known whether gliclazide or pioglitazone passes into breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor.
💊 Overdose Management
Overdose of this medicine can cause severe hypoglycemia. Symptoms include confusion, seizures, loss of consciousness, and coma. If overdose is suspected, seek emergency medical attention immediately. Treatment includes administration of glucose (oral if conscious, intravenous if unconscious) and close monitoring of blood glucose and vital signs. Hemodialysis may be considered for gliclazide overdose, but pioglitazone is not effectively removed by dialysis. Supportive care should be provided.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is less than half the dosing interval away. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Take it with the first main meal of the day to reduce stomach upset and lower the risk of low blood sugar. Carry a fast-acting sugar source such as glucose tablets or candy with you at all times in case of hypoglycemia. Check your blood sugar regularly as advised. Avoid skipping meals, and maintain a consistent eating schedule. Limit alcohol intake because it can increase the risk of low blood sugar and liver problems. Inform your doctor if you have heart, liver, or kidney disease, or if you are planning pregnancy. Do not share this medicine with anyone else. Keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of hypoglycemia, heart failure, and bone fractures. The dose should be started at the lower end and adjusted carefully. Regular monitoring of blood sugar, kidney function, and heart function is essential. Falls risk should be assessed.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative, usually insulin. Good blood sugar control before and during pregnancy is important for the health of both mother and baby.
🏥 Post-Surgery Considerations
After surgery, blood sugar levels can fluctuate. This medicine may need to be temporarily stopped or adjusted. Consult your surgeon and diabetes doctor for guidance. Monitor blood sugar closely during the recovery period.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. Dental procedures can cause stress and affect blood sugar levels. You may need to adjust your dose or monitor blood sugar more frequently around the time of the procedure. Good oral hygiene is important for people with diabetes.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise can lower blood sugar and increase the risk of hypoglycemia, especially when combined with this medicine. Check your blood sugar before and after exercise. Carry a fast-acting sugar source. If your blood sugar is low before exercise, eat a snack first. Consult your doctor before starting a new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause low blood sugar, which can affect your ability to drive or operate machinery. Do not drive if you feel shaky, dizzy, or confused. Take breaks and eat regular meals. Inform your employer about your condition and the medicine you are taking. With proper management, most people can continue their normal work and daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as heart failure, liver injury, or severe hypoglycemia, your doctor may advise you to stop. Always seek medical advice before discontinuing.
📅 Long-Term Use Effects
Long-term use of this medicine may be associated with an increased risk of heart failure, bladder cancer, bone fractures, and weight gain. Regular monitoring of blood sugar, liver function, kidney function, and heart function is recommended. Periodic eye exams are also advised. The benefits of improved blood sugar control generally outweigh the risks, but your doctor will monitor you closely.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are the cornerstone of diabetes management and can help reduce the need for medicines.
Evidence: Well-establishedMetformin, DPP-4 inhibitors, SGLT2 inhibitors, or GLP-1 receptor agonists may be alternatives depending on your condition.
Evidence: Well-establishedInsulin may be required if oral medicines are not effective or contraindicated.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, people with diabetes are at higher risk of infections, so ensure you are up to date with recommended vaccinations such as influenza, pneumococcal, and hepatitis B vaccines. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from light and moisture. If crossing time zones, consult your doctor about adjusting the timing of your dose to maintain blood sugar control. Carry a fast-acting sugar source and a glucagon emergency kit if prescribed. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within a few hours, but the full effect on HbA1c may take 2-3 months. Continue taking it as prescribed and monitor your blood sugar regularly.
A: This medicine is not recommended in severe kidney disease. Your doctor may adjust the dose or choose a different medicine based on your kidney function.
A: If you have symptoms of low blood sugar (shakiness, sweating, confusion, hunger), take fast-acting sugar such as glucose tablets, candy, or fruit juice immediately. If symptoms persist, seek medical help.
A: No, do not stop taking this medicine without consulting your doctor. Stopping suddenly can cause your blood sugar to rise again. Your doctor will decide if and when to adjust or stop the medicine.
A: Yes, weight gain is a common side effect of this medicine, especially due to pioglitazone. A healthy diet and regular exercise can help manage weight.
🤔 Common Patient Concerns
🔄 Substitutes for reclimet-pg 30 tablet sr
View AllAlternative brands with exact same active ingredient:
-
bytey total 30mg/15mg/500mg tablet srArrient Healthcare Pvt Ltd ₹79.69 1.3% CHEAPER
-
dayclazide total 30mg/15mg/500mg tablet srDaylon Healthcare ₹80.00 0.9% CHEAPER
-
carryl mp 30mg/15mg/500mg tablet sr4Care Lifescience Pvt Ltd ₹84.38 4.5% COSTLIER
-
dianorm total 30 tablet srMicro Labs Ltd ₹86.00 6.5% COSTLIER
-
aim7 30mg/15mg/500mg tablet xrEris Lifesciences Ltd ₹160.94 99.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes permanently.
Fact: This medicine helps control blood sugar but does not cure diabetes. It must be continued along with diet and exercise as advised by your doctor. - Myth: I can stop taking this medicine once my sugar levels are normal.
Fact: Do not stop taking this medicine without consulting your doctor. Stopping suddenly can cause blood sugar levels to rise again. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine is not recommended during pregnancy. Insulin is the preferred treatment for diabetes in pregnancy. - Myth: Taking this medicine means I can eat whatever I want.
Fact: A healthy diet and regular exercise are essential for managing diabetes. This medicine works best when combined with lifestyle changes.
🔄 Alternative Options
Generic Alternatives
- Gliclazide + Pioglitazone combination (generic)
Brand Alternatives
- Bytey Total 30mg/15mg/500mg tablet SR