Reast Tablet - Paracetamol (500mg) + Phenylpropanolamine (10mg) medicine

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🏭 Alliance Remedies 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Oct 27, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term symptomatic relief.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is Reast Tablet used for?

This medicine is a combination of Paracetamol and Phenylpropanolamine used for temporary relief of nasal congestion, headache, and fever due to cold or allergies. It works by reducing pain and fever and shrinking nasal blood vessels.

  • Generic Name: Paracetamol (500mg) + Phenylpropanolamine (10mg)
  • Manufacturer: Alliance Remedies
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Reast Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल और फेनिलप्रोपेनॉलामाइन का संयोजन है, जिसका उपयोग सर्दी, एलर्जी या साइनसाइटिस के कारण होने वाली नाक की भीड़, सिरदर्द और बुखार से राहत के लिए किया जाता है। यह दवा नाक के रक्त वाहिकाओं को सिकोड़कर भीड़ को कम करती है और दर्द व बुखार को कम करती है। यह अल्पकालिक उपयोग के लिए है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट की परेशानी, मुँह सूखना, बेचैनी और हल्का चक्कर आना शामिल हैं। फेनिलप्रोपेनॉलामाइन के कारण हृदय गति बढ़ सकती है और रक्तचाप बढ़ सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज रक्तचाप, अनियमित हृदय गति, मतिभ्रम या दौरे शामिल हो सकते हैं।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। शराब का सेवन न करें क्योंकि इससे लीवर को नुकसान हो सकता है। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड विकार या लीवर/किडनी की समस्या है तो डॉक्टर को बताएं। 5-7 दिनों से अधिक उपयोग न करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 Reast Tablet Uses & Benefits

[{"condition":"Common cold","description":"Relieves nasal congestion, headache, and fever associated with the common cold.","evidence":"Well-established for short-term symptomatic relief."},{"condition":"Allergic rhinitis","description":"Reduces nasal stuffiness and sinus pressure due to allergies.","evidence":"Well-established for short-term use."},{"condition":"Sinusitis","description":"Helps alleviate sinus congestion and associated pain.","evidence":"Well-established for symptomatic relief."}]

Off-label uses: []

Primary treatment for: Common cold

Also treats: Allergic rhinitis, Sinusitis

📋 Drug Information

Generic Name(s)Paracetamol (500mg) + Phenylpropanolamine (10mg)
Brand NameReast Tablet
ManufacturerAlliance Remedies
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
Monitor your blood pressure if you have hypertension.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Nasal congestion
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
Paracetamol component reduces fever.
Likely Use
❌
Chronic joint pain
This medicine is not a primary treatment for chronic pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and almost completely absorbed from the gastrointestinal tract. Phenylpropanolamine is also absorbed from the gastrointestinal tract.
DistributionParacetamol distributes widely into body tissues. Phenylpropanolamine distribution is not well characterized.
Protein BindingParacetamol: approximately 10-25% bound to plasma proteins. Phenylpropanolamine: Not established from the available information.
MetabolismParacetamol is metabolized primarily in the liver via glucuronidation and sulfation, with a small fraction via CYP2E1 to a toxic metabolite. Phenylpropanolamine undergoes limited metabolism.
Half-LifeParacetamol: 2-3 hours. Phenylpropanolamine: Not established from the available information.
ExcretionParacetamol is excreted in urine as metabolites. Phenylpropanolamine is excreted unchanged in urine.
BioavailabilityParacetamol: approximately 80-100%. Phenylpropanolamine: Not established from the available information.
Onset of ActionParacetamol: 30-60 minutes. Phenylpropanolamine: 15-30 minutes.
Peak Plasma TimeParacetamol: 0.5-2 hours. Phenylpropanolamine: 1-2 hours.
Duration of ActionParacetamol: 4-6 hours. Phenylpropanolamine: 4-6 hours.

How It Works

This medicine combines two active ingredients. Paracetamol acts primarily in the central nervous system to reduce pain and fever by inhibiting prostaglandin synthesis. Phenylpropanolamine is a sympathomimetic amine that stimulates alpha-adrenergic receptors, causing vasoconstriction in the nasal mucosa, which reduces swelling and congestion. The combination provides symptomatic relief of cold and allergy symptoms.

Mechanism Steps

1
Paracetamol action: Paracetamol inhibits prostaglandin synthesis in the central nervous system, reducing pain and fever.
2
Phenylpropanolamine action: Phenylpropanolamine stimulates alpha-adrenergic receptors on nasal blood vessels, causing vasoconstriction and reduced congestion.

💡 How to Take Reast Tablet

Strength: Tablet: Paracetamol 500 mg + Phenylpropanolamine 10 mg

1Take this medicine orally with a full glass of water.
2Take with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the dosage instructions on the label or as prescribed by your doctor.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet every 4 to 6 hours as needed for symptoms, not to exceed 6 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageUse with caution in elderly patients, who may be more sensitive to the effects of Phenylpropanolamine. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment may be required in renal impairment. Consult a clinician.
Hepatic ImpairmentAvoid in severe hepatic impairment. Dose adjustment may be required in mild to moderate impairment. Consult a clinician.
Maximum Daily DoseParacetamol: 3000 mg per day (6 tablets). Phenylpropanolamine: 60 mg per day (6 tablets).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Reast Tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce stomach upset. Consult doctor if persistent.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Usually resolves.
Restlessness (Common (5-10%))
Avoid caffeine. Consult doctor if severe.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Severe hypertension (Rare (<0.1%))
Seek immediate medical attention if you experience severe headache, blurred vision, or chest pain.
Cardiac arrhythmias (Rare (<0.1%))
Seek immediate medical attention if you notice palpitations or irregular heartbeat.
Liver damage (Paracetamol overdose) (Rare (<0.1%))
Seek immediate medical attention if you suspect overdose, even if you feel well.

⚠️ Rare Side Effects

Hallucinations
Discontinue and seek medical attention.
Seizures
Seek emergency medical care.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Warfarin Moderate
Antihypertensives Moderate

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Other sympathomimetics

⚡ Moderate Interactions

  • Warfarin
  • Antihypertensives

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage from Paracetamol and may worsen dizziness or drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Uncontrolled hypertension","Severe coronary artery disease","Hyperthyroidism","MAOI therapy within 14 days","Severe liver disease","Known hypersensitivity to any component"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disease.","Avoid in patients with glaucoma or urinary retention.","Do not exceed recommended dose of Paracetamol.","Avoid alcohol.","Not for children under 12 years without medical advice."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use.

💊 Overdose Management

Seek immediate medical attention. Paracetamol overdose can cause delayed liver damage. Treatment includes activated charcoal, N-acetylcysteine, and supportive care. Phenylpropanolamine overdose may cause hypertension, tachycardia, and CNS stimulation; manage symptomatically.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as directed by your doctor. Do not exceed the recommended dose or duration of use. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Do not consume alcohol while taking this medicine as it increases the risk of liver damage. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid disorders, or liver/kidney problems. Do not use this medicine for more than 5-7 days without medical advice. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular effects of Phenylpropanolamine. Use with caution and monitor blood pressure.

🤰 Pregnancy Planning (TTC)

Consult your doctor before use if you are pregnant, planning pregnancy, or breastfeeding. The safety of this combination in pregnancy is not well established.

🏥 Post-Surgery Considerations

Consult your surgeon before use, as Phenylpropanolamine may affect blood pressure and heart rate.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain anesthetics or medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or fatigued. Stay hydrated during exercise.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

May cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Stop this medicine if symptoms persist beyond 7 days or if you experience severe side effects. Consult your doctor before stopping if you have been on prolonged therapy.

📅 Long-Term Use Effects

Long-term use of Paracetamol can increase the risk of liver damage, especially with high doses or alcohol consumption. Phenylpropanolamine may cause persistent hypertension or cardiac issues. Regular monitoring of liver function and blood pressure is advised if prolonged use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Can help relieve nasal congestion without medication.

Evidence: Well-established
Steam inhalation

May provide temporary relief from nasal stuffiness.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before vaccination if you are unwell.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule accordingly, but do not exceed maximum daily dose. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old office worker with common cold
Started this medicine as prescribed for nasal congestion and headache. Within 30 minutes noticed significant relief. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 50-year-old with allergic rhinitis
Used this medicine for seasonal allergies. Experienced mild dizziness but symptoms improved. Advised to avoid driving until effects known.
💡 Lesson: Be aware of potential dizziness and avoid driving if affected.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Paracetamol starts working within 30-60 minutes, while Phenylpropanolamine may take 15-30 minutes to relieve congestion.

Q: Can I take it with other cold medicines?

A: Avoid taking with other products containing Paracetamol or decongestants to prevent overdose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Reast Tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: It only relieves symptoms; it does not cure the underlying infection.
  • Myth: It is safe to take with any other medication.
    Fact: It can interact with several drugs, including MAOIs and antihypertensives.

📊 Comparison with Similar Medicines

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