aceeforte 150mg/2.5mg tablet - Diethylcarbamazine (150mg) + Chlorpheniramine Maleate (2.5mg) medicine

Carbamyl Forte 150 mg/2.5 mg Tablet: Complete Medicine Guide

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🏭 Alliance Remedies 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for Diethylcarbamazine in filarial infections. Limited for the combination with Chlorpheniramine.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of the face, lips, or throat
  • Severe skin rash or itching
  • Yellowing of the skin or eyes
  • Dark urine or severe abdominal pain
  • Blurred vision or eye pain
  • Confusion, seizures, or severe headache

If experiencing severe symptoms, call emergency services immediately.

What is aceeforte 150mg/2.5mg tablet used for?

This medicine is a combination of Diethylcarbamazine and Chlorpheniramine used to treat lymphatic filariasis and other filarial infections. It works by killing the parasitic worms and reducing allergic reactions.

  • Generic Name: Diethylcarbamazine + Chlorpheniramine Maleate
  • Manufacturer: Alliance Remedies
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 aceeforte 150mg/2.5mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डाइएथिलकार्बामाज़ीन और क्लोरफेनिरामाइन का संयोजन है, जिसका उपयोग लिम्फैटिक फाइलेरिया और अन्य फाइलेरिया संक्रमणों के इलाज के लिए किया जाता है। यह परजीवी कीड़ों को मारती है और एलर्जी प्रतिक्रियाओं को कम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, चक्कर आना, नींद आना, सिरदर्द और भूख में कमी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया, दृष्टि समस्याएं या यकृत विषाक्तता शामिल हो सकती है।

सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। खुराक को न बदलें और न ही डॉक्टर की सलाह के बिना इलाज बंद करें। यह दवा नींद का कारण बन सकती है, इसलिए वाहन चलाने या भारी मशीनरी चलाने से बचें। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो अपने डॉक्टर को बताएं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 aceeforte 150mg/2.5mg tablet Uses & Benefits

  • [{"condition":"Lymphatic filariasis","description":"This medicine is used to treat lymphatic filariasis caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori.
  • It helps eliminate microfilariae from the blood and reduces the risk of progression to elephantiasis.","evidence":"Well-established"},{"condition":"Tropical pulmonary eosinophilia","description":"This medicine is effective in treating tropical pulmonary eosinophilia, a condition caused by hypersensitivity to filarial parasites.
  • It helps relieve respiratory symptoms and reduces eosinophil counts.","evidence":"Well-established"},{"condition":"Loiasis","description":"This medicine is used to treat loiasis caused by Loa loa.
  • It reduces microfilarial load and helps manage symptoms.
  • However, caution is needed in patients with high microfilarial counts due to risk of severe reactions.","evidence":"Established"},{"condition":"Onchocerciasis","description":"This medicine may be used in some cases of onchocerciasis, but it is not the first-line treatment.
  • It can cause severe allergic reactions due to dying microfilariae, so it must be used with caution under medical supervision.","evidence":"Limited"}]

Off-label uses: [{"condition":"Allergic rhinitis","description":"The chlorpheniramine component may provide relief from allergic rhinitis symptoms, but this combination is not primarily indicated for this purpose.","evidence":"Limited"}]

Primary treatment for: Lymphatic filariasis

Also treats: Tropical pulmonary eosinophilia, Loiasis

📋 Drug Information

Generic Name(s)Diethylcarbamazine + Chlorpheniramine Maleate
Brand NameAceeforte 150mg/2.5mg Tablet
ManufacturerAlliance Remedies
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAnthelmintic + Antihistamine
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineDiethylcarbamazine is recommended by WHO for the treatment of lymphatic filariasis in combination with other antifilarial drugs. However, this specific combination with Chlorpheniramine is not specifically mentioned in WHO guidelines.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid driving or operating machinery until you know how this medicine affects you.
3
Do not consume alcohol while taking this medicine.
4
Complete the full course as prescribed, even if you feel better.
5
Inform your doctor if you experience vision changes or severe allergic reactions.
6
Keep all follow-up appointments to monitor your response to treatment.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Swelling in legs or arms
This medicine is commonly prescribed for lymphatic filariasis which causes swelling.
Likely Use
✅
Persistent cough and wheezing
May be used for tropical pulmonary eosinophilia.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDiethylcarbamazine is rapidly absorbed from the gastrointestinal tract after oral administration. Chlorpheniramine is also well absorbed orally.
DistributionDiethylcarbamazine is distributed widely throughout the body, including into the bloodstream and tissues. Chlorpheniramine is distributed into various tissues, including the central nervous system.
Protein BindingNot established from the available information.
MetabolismDiethylcarbamazine is partially metabolized in the liver. Chlorpheniramine is metabolized in the liver by cytochrome P450 enzymes.
Half-LifeDiethylcarbamazine: approximately 8-12 hours. Chlorpheniramine: approximately 12-43 hours.
ExcretionDiethylcarbamazine is excreted primarily in the urine. Chlorpheniramine is excreted in the urine as metabolites.
BioavailabilityNot established from the available information.
Onset of ActionDiethylcarbamazine begins to reduce microfilariae in the blood within hours to days. Chlorpheniramine's antihistamine effect starts within 30-60 minutes.
Peak Plasma TimeDiethylcarbamazine: 1-2 hours. Chlorpheniramine: 2-6 hours.
Duration of ActionDiethylcarbamazine: effects on microfilariae may last for days to weeks. Chlorpheniramine: 4-6 hours.

How It Works

Diethylcarbamazine works by altering the surface of microfilariae, making them more susceptible to destruction by the host's immune system. It also immobilizes adult worms and may block their ability to evade immune responses. Chlorpheniramine Maleate is a first-generation antihistamine that blocks histamine H1 receptors, reducing allergic symptoms such as itching, sneezing, and rash that can occur during treatment.

Mechanism Steps

1
Immobilization of microfilariae: Diethylcarbamazine alters the microfilarial surface, causing them to become immobile and more vulnerable to immune attack.
2
Immune-mediated destruction: The host's immune system recognizes and destroys the damaged microfilariae, leading to their clearance from the bloodstream.
3
Effect on adult worms: Diethylcarbamazine also affects adult worms, though the exact mechanism is not fully understood. It may interfere with their metabolism and reproduction.
4
Histamine blockade: Chlorpheniramine blocks histamine H1 receptors, preventing allergic symptoms that may arise from the death of parasites.

💡 How to Take aceeforte 150mg/2.5mg tablet

Strength: Each tablet contains Diethylcarbamazine 150 mg and Chlorpheniramine Maleate 2.5 mg.

1Take this medicine orally with a glass of water.
2Take it with food to reduce stomach upset.
3Swallow the tablet whole. Do not crush or chew.
4Take it at the same time each day to maintain consistent levels.
5Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose for lymphatic filariasis is 6 mg/kg/day of Diethylcarbamazine in divided doses for 12 days. For tropical pulmonary eosinophilia, the dose is 6 mg/kg/day for 14-21 days. The Chlorpheniramine component is fixed at 2.5 mg per tablet. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the sedative effects of Chlorpheniramine. Use with caution and monitor for drowsiness and dizziness. Dose adjustment may be needed based on renal function.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum daily dose of Diethylcarbamazine is 6 mg/kg/day. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Alcohol
Avoid
Increases drowsiness and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of aceeforte 150mg/2.5mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Drowsiness (Common (10-15%))
Avoid driving or operating machinery. Consult your doctor if it interferes with daily activities.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid alcohol.
Headache (Common (5-10%))
Rest and stay hydrated. Consult your doctor if it persists.
Loss of appetite (Common (5-10%))
Eat small, frequent meals. Consult your doctor if it continues.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience difficulty breathing, swelling of the face, lips, or throat, or a severe rash.
Vision problems (Rare (<0.1%))
Report any changes in vision, such as blurred vision or eye pain, to your doctor immediately.
Liver toxicity (Rare (<0.1%))
Seek medical attention if you notice yellowing of the skin or eyes, dark urine, or severe abdominal pain.

⚠️ Rare Side Effects

Encephalopathy
Seek immediate medical attention if you experience confusion, seizures, or severe headache.
Retinopathy
Report any vision changes to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
CNS depressants Major
MAOIs Moderate
Tricyclic antidepressants Moderate
Other antihistamines Minor

🚨 Major Interactions

  • Alcohol
  • CNS depressants (e.g., benzodiazepines, opioids)

⚡ Moderate Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine as it can increase drowsiness, dizziness, and the risk of other side effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to Diethylcarbamazine or Chlorpheniramine","Severe renal impairment","Severe hepatic impairment","Onchocerciasis with ocular involvement (due to risk of severe reactions)"]

⚠️ Warnings & Precautions

["May cause drowsiness. Avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","Use with caution in patients with kidney or liver disease.","Use with caution in patients with a history of seizures.","Not recommended for children under 2 years of age unless prescribed by a doctor.","Inform your doctor if you are pregnant or breastfeeding."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, dizziness, nausea, and vomiting. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop treatment without consulting your doctor. This medicine can cause drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. Avoid drinking alcohol while taking this medicine as it can increase drowsiness and dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Tell your doctor about all other medicines you are taking, especially sedatives, antihistamines, or antidepressants. Keep this medicine out of reach of children. Store it in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the sedative effects of Chlorpheniramine. Use with caution and monitor for drowsiness, dizziness, and confusion. Dose adjustment may be needed based on renal function.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with anesthetic agents and increase sedation.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may cause dry mouth and increase the risk of dental problems. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hygiene to prevent reinfection.
🥗
Use mosquito nets to prevent mosquito bites that spread filariasis.
😴
Stay hydrated and eat a balanced diet.
💧
Get adequate rest, especially if you feel drowsy.
🧘
Avoid alcohol while on this medicine.
🌞
Follow up regularly with your doctor.

🏋️ Exercise Considerations

This medicine can cause drowsiness and dizziness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you.

🥗 Diet Recommendations

Take the medicine with food to reduce nausea.
Eat small, frequent meals if you experience loss of appetite.
Stay well hydrated.
Avoid alcohol.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take it at bedtime if it makes you sleepy.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Complete the full course as prescribed. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine may require monitoring of liver and kidney function. Prolonged use of Chlorpheniramine may lead to tolerance or dependence. Regular follow-up with your doctor is recommended to assess treatment response and adjust therapy as needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Ivermectin with Albendazole

Alternative combination therapy for lymphatic filariasis.

Evidence: Well-established
Doxycycline

May be used as an adjunct to target Wolbachia bacteria in filarial worms.

Evidence: Emerging

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information. Consult your doctor regarding vaccinations while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking the medicine at the same intervals as prescribed. Check local customs regulations regarding prescription medicines before you travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man from a filaria-endemic region
He was diagnosed with lymphatic filariasis after experiencing swelling in his legs and episodes of fever. He was prescribed this medicine for 12 days. He took it regularly with food and reported mild drowsiness initially, which subsided after a few days. His microfilarial count reduced significantly, and his swelling improved.
💡 Lesson: Taking the medicine with food and completing the full course is essential for effective treatment.
👤 A 50-year-old woman with tropical pulmonary eosinophilia
She had persistent cough and wheezing. After diagnosis, she was started on this medicine for 21 days. She experienced nausea and dizziness in the first week, but these were managed by taking the tablet after meals. Her respiratory symptoms improved gradually, and follow-up tests showed normal eosinophil counts.
💡 Lesson: Side effects are often temporary and can be managed with simple measures like taking the medicine with food.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Diethylcarbamazine starts reducing microfilariae in the blood within hours to days. Symptom improvement may take a few weeks depending on the condition.

Q: Can I take this medicine with other medications?

A: Inform your doctor about all other medicines you are taking, especially sedatives, antihistamines, or antidepressants, as interactions may occur.

Q: Is it safe to take during pregnancy?

A: Consult your doctor if you are pregnant or planning to become pregnant. The safety of this medicine during pregnancy is not well established.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for aceeforte 150mg/2.5mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any worm infection.
    Fact: This medicine is specifically for filarial infections. It is not effective against other types of worms.
  • Myth: You can stop taking this medicine once symptoms improve.
    Fact: You must complete the full course as prescribed to ensure the infection is fully treated.

🔄 Alternative Options

Generic Alternatives

  • Diethylcarbamazine 150 mg + Chlorpheniramine Maleate 2.5 mg tablet

Brand Alternatives

  • Carbamyl Forte 150 mg/2.5 mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Ivermectin","composition":"Ivermectin","uses":"Lymphatic filariasis, onchocerciasis","key_difference":"Different mechanism of action; often used in combination with albendazole."},{"medicine":"Albendazole","composition":"Albendazole","uses":"Lymphatic filariasis, intestinal worms","key_difference":"Broad-spectrum anthelmintic; often used with diethylcarbamazine or ivermectin."}]

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