quickstin 12.5mg dry syrup - Colistin Sulphate (12.5mg) medicine

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🏭 Cure Quick Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 25, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Established for specific susceptible infections; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Oct 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is quickstin 12.5mg dry syrup used for?

This medicine is an oral antibiotic suspension containing Colistin Sulphate, used to treat certain gastrointestinal infections caused by susceptible Gram-negative bacteria. It works by disrupting bacterial cell membranes, leading to bacterial death. It is poorly absorbed from the gut, so its action is mainly local. It should only be used under medical supervision.

  • Generic Name: Colistin Sulphate (12.5mg)
  • Manufacturer: Cure Quick Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 quickstin 12.5mg dry syrup के बारे में (Hindi Summary)

उपयोग: यह दवा कोलिस्टिन सल्फेट नामक एंटीबायोटिक का मौखिक सस्पेंशन है। इसका उपयोग कुछ विशिष्ट ग्राम-नेगेटिव बैक्टीरिया के कारण होने वाले पेट और आंतों के संक्रमणों के इलाज के लिए किया जाता है। यह दवा बैक्टीरिया की कोशिका झिल्ली को नष्ट करके उन्हें मार देती है। चूंकि यह दवा आंतों से बहुत कम अवशोषित होती है, इसलिए इसका असर मुख्य रूप से आंतों में ही होता है। इसका उपयोग डॉक्टर के पर्चे के बिना न करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, दस्त, पेट में असहजता और भूख में कमी शामिल हो सकते हैं। कुछ रोगियों में त्वचा पर चकत्ते या खुजली भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में कठिनाई, चेहरे या गले में सूजन, या पेशाब कम आना जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। दवा की खुराक खुद से न बदलें और न ही बीच में बंद करें, भले ही आपको बेहतर महसूस हो। हर बार उपयोग से पहले सस्पेंशन को अच्छी तरह हिलाएं। सही मात्रा मापने के लिए दिए गए कप या सिरिंज का उपयोग करें। अगर आपको गुर्दे की बीमारी, मांसपेशियों की कमजोरी या किसी एंटीबायोटिक से एलर्जी है, तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। इस दवा को दूसरों के साथ साझा न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 quickstin 12.5mg dry syrup Uses & Benefits

[{"condition":"Gastrointestinal infections caused by susceptible Gram-negative bacteria","description":"This medicine is used to treat certain bacterial infections of the gut, such as those caused by susceptible strains of Escherichia coli, where local action in the intestine is desired.","evidence":"Established for specific susceptible infections"},{"condition":"Diarrhea associated with susceptible organisms","description":"In some clinical settings, this medicine may be prescribed as part of the management of infectious diarrhea caused by susceptible bacteria, though it is not a first-line treatment for all diarrheal illnesses.","evidence":"Limited to specific clinical scenarios"}]

Off-label uses: [{"condition":"Selective decontamination of the digestive tract","description":"In intensive care settings, oral Colistin Sulphate has been used off-label as part of selective decontamination regimens to reduce the risk of infections in critically ill patients.","evidence":"Limited; used in specialized settings"}]

Primary treatment for: Gastrointestinal infections caused by susceptible Gram-negative bacteria

Also treats: Infectious diarrhea, Selective decontamination of the digestive tract (off-label)

📋 Drug Information

Generic Name(s)Colistin Sulphate (12.5mg)
Brand Namequickstin 12.5mg dry syrup
ManufacturerCure Quick Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassCell membrane active agent
Route of AdministrationOral
StorageStore at room temperature (15-30°C). Protect from light and moisture. Do not freeze. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine only when a susceptible Gram-negative infection is confirmed or strongly suspected.
2
Advise patients to complete the full course even if symptoms improve to prevent resistance.
3
Monitor renal function if the patient has kidney disease or if prolonged therapy is considered.
4
Warn patients about the rare risk of neurotoxicity and advise them to report tingling or confusion.
5
Instruct patients to shake the suspension well before each dose and use a proper measuring device.
6
Avoid concurrent use with other nephrotoxic or neurotoxic drugs unless benefits outweigh risks.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

❌
Chronic joint pain
This medicine is not indicated for joint pain.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Diarrhea
This medicine may be prescribed for specific bacterial diarrhea.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWhen taken orally as a suspension, Colistin Sulphate is poorly absorbed from the gastrointestinal tract, which limits systemic exposure and localizes its action to the gut.
DistributionDue to poor oral absorption, systemic distribution is minimal when this medicine is taken by mouth. Any absorbed drug may distribute to tissues, but detailed distribution data for the oral suspension are not well established.
Protein BindingNot established from the available information.
MetabolismColistin Sulphate is not significantly metabolized in the body; it is primarily eliminated unchanged.
Half-LifeNot established from the available information for the oral suspension. For systemically absorbed colistin, the half-life is approximately 2 to 3 hours in patients with normal renal function, but this may not apply to the oral route.
ExcretionAny absorbed Colistin Sulphate is primarily excreted unchanged by the kidneys. Unabsorbed drug is eliminated in the feces.
BioavailabilityOral bioavailability of Colistin Sulphate is very low, estimated to be less than 1% to 2% in most studies.
Onset of ActionThe onset of action for this medicine in the gut is not precisely defined, but effects on susceptible bacteria begin as the drug reaches the intestinal tract after ingestion.
Peak Plasma TimeNot established from the available information for the oral suspension due to negligible systemic absorption.
Duration of ActionNot established from the available information.

How It Works

Colistin Sulphate is a polymyxin antibiotic that exerts its bactericidal effect by interacting with the lipopolysaccharide component of the outer membrane of Gram-negative bacteria. This interaction displaces calcium and magnesium ions, destabilizing the membrane and increasing its permeability. The resulting leakage of intracellular contents leads to bacterial cell death. Because of its mechanism, it is active against many Gram-negative organisms, including some that are resistant to other antibiotics.

Mechanism Steps

1
Binding to lipopolysaccharide: Colistin Sulphate binds to the lipid A portion of lipopolysaccharide in the outer membrane of Gram-negative bacteria.
2
Displacement of divalent cations: This binding displaces calcium and magnesium ions that normally stabilize the membrane.
3
Membrane destabilization: The displacement weakens the outer membrane, increasing its permeability.
4
Cell leakage and death: Essential intracellular components leak out, leading to bacterial cell death.

💡 How to Take quickstin 12.5mg dry syrup

Strength: Oral suspension containing Colistin Sulphate 12.5 mg per 5 mL (or as specified by the manufacturer).

1Shake the suspension well before each use.
2Measure the prescribed dose using the measuring cup or syringe provided.
3Take the medicine orally, with or without food.
4If you miss a dose, follow the missed dose instructions.
5Complete the full course as prescribed by your doctor.

Dosage Information

Adult DosageThe dosage of this medicine must be individualized by a qualified clinician based on the specific infection, its severity, and the patient's renal function. For oral Colistin Sulphate, typical adult doses range from 1.5 to 3 million units three times daily, but the exact dose and duration depend on the clinical situation. Do not self-medicate. Follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may have reduced renal function, which can increase the risk of side effects if systemic absorption occurs. Dose selection should be cautious, and renal function should be monitored. Consult a doctor for individualized dosing.
Renal ImpairmentIn patients with renal impairment, dose reduction may be necessary if the medicine is absorbed systemically. However, because oral absorption is minimal, dose adjustment is often not required for the oral suspension. Consult a doctor for guidance.
Hepatic ImpairmentNo specific dosage adjustment is established for hepatic impairment. Consult a doctor.
Maximum Daily DoseThe maximum daily dose should be determined by a qualified clinician based on the indication and patient factors. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
May be taken with or without food
Food does not significantly affect absorption.
Grapefruit
No known interaction
No specific interaction reported.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of quickstin 12.5mg dry syrup

✅ Common Side Effects

Nausea (Common (may affect up to 1 in 10 people))
Try taking with a small amount of food if permitted. If nausea persists or worsens, consult your doctor.
Vomiting (Common (may affect up to 1 in 10 people))
Stay hydrated with small sips of clear fluids. If vomiting is severe or prevents keeping the medicine down, contact your doctor.
Diarrhea (Common (may affect up to 1 in 10 people))
Ensure adequate fluid intake. If diarrhea becomes severe or bloody, seek medical advice promptly.
Stomach discomfort (Common (may affect up to 1 in 10 people))
Taking the medicine with a small snack may help. If discomfort continues, talk to your doctor.
Loss of appetite (Uncommon (may affect up to 1 in 100 people))
Eat small, frequent meals. If appetite loss leads to weakness, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (may affect up to 1 in 1,000 people))
Seek emergency medical help immediately if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Kidney injury (nephrotoxicity) (Rare with oral use due to poor absorption, but possible if systemic absorption occurs)
Report decreased urine output, swelling in the legs, or unusual fatigue to your doctor promptly. Regular monitoring may be needed if used for prolonged periods.
Neurotoxicity (e.g., tingling, dizziness, confusion) (Rare)
If you experience numbness, tingling, muscle weakness, or confusion, contact your doctor immediately.
Clostridioides difficile-associated diarrhea (Rare)
Seek medical attention if you develop severe, persistent diarrhea, abdominal pain, or fever during or after treatment.

⚠️ Rare Side Effects

Respiratory paralysis or apnea
This is a medical emergency. Seek immediate medical attention if you experience difficulty breathing or muscle weakness.
Nephrotoxicity with high systemic levels
Regular kidney function tests may be advised if there is a risk of systemic absorption.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Aminoglycosides Major
Amphotericin B Major
Cyclosporine Major
Neuromuscular blockers Major
Other antibiotics Moderate

🚨 Major Interactions

  • Other nephrotoxic drugs (e.g., aminoglycosides, amphotericin B, cyclosporine)
  • Neuromuscular blocking agents (e.g., vecuronium, succinylcholine)

⚡ Moderate Interactions

  • Other antibiotics

🍷 Alcohol Interaction

There is no specific interaction known between alcohol and this medicine. However, alcohol can irritate the stomach and worsen gastrointestinal side effects. It is advisable to avoid alcohol while you are recovering from an infection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Colistin Sulphate or any component of the formulation.","Known hypersensitivity to polymyxin antibiotics."]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment may be required if systemic absorption occurs.","Avoid concurrent use with other nephrotoxic or neurotoxic drugs.","Not effective against viral infections.","May cause Clostridioides difficile-associated diarrhea; if severe diarrhea occurs, consider this diagnosis.","Do not use for prolonged periods without medical supervision.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether Colistin Sulphate is excreted in human breast milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a nursing woman. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose with this oral suspension is unlikely to cause serious systemic effects due to poor absorption. However, if a large amount is ingested, seek medical attention. Treatment is symptomatic and supportive. In case of accidental overdose, contact a poison control center or emergency room immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop treatment early without medical advice, even if you feel better, as this can lead to incomplete eradication of the infection and possible resistance. Shake the suspension well before each use to ensure the medicine is evenly mixed. Use a proper measuring device to get the correct dose. Inform your doctor if you have kidney disease, muscle weakness (myasthenia gravis), or any allergies to antibiotics. Avoid taking this medicine with other antibiotics unless specifically instructed, as some combinations may be incompatible. Keep out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, tell your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms. Store as directed and discard any unused portion after the prescribed course or as advised by your pharmacist.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function, which can increase the risk of side effects if the medicine is absorbed systemically. Close monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may need to be stopped temporarily, especially if there is a risk of interaction with other medications.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are usually needed, but it is important for your dentist to know your medication history.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on your body.
🥗
Regular low-impact exercise like walking or swimming.
😴
Practice good hygiene to prevent infections.
💧
Include probiotic-rich foods like yogurt to support gut health.
🧘
Get adequate sleep to boost your immune system.

🏋️ Exercise Considerations

If you experience dizziness or muscle weakness while taking this medicine, avoid strenuous exercise and consult your doctor.

🥗 Diet Recommendations

Stay well hydrated
Eat a balanced diet rich in fruits and vegetables
Include probiotic-rich foods to support gut health
Avoid spicy and oily foods if you have stomach upset

💼 Impact on Daily Work & Life

This medicine may cause dizziness or confusion in rare cases. If affected, avoid driving or operating heavy machinery. Otherwise, it should not significantly impact your daily activities.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Complete the full prescribed course. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to bacterial resistance and, rarely, superinfections. If systemic absorption occurs, there is a risk of kidney and nerve damage. Regular monitoring may be required if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

Can help restore gut flora during and after antibiotic treatment.

Evidence: Limited
Hydration and electrolyte replacement

Important for managing diarrhea and preventing dehydration.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for a vaccine, inform your doctor that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes in checked baggage. Store at room temperature and protect from light and moisture. If crossing time zones, continue your dosing schedule as close to the prescribed intervals as possible. Check customs regulations for carrying prescription medicines into your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with a gut infection
Was prescribed this medicine for a susceptible bacterial infection. He completed the full course and recovered fully. He reported mild nausea initially, which subsided after taking the medicine with a small snack.
💡 Lesson: Taking the medicine with a small snack can reduce gastrointestinal side effects and improve adherence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start to feel better within 1-2 days, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, this medicine can be taken with or without food. Taking it with a small snack may help reduce stomach upset.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established. Consult a pediatrician for appropriate use in children.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember if it is not almost time for your next dose. Do not double dose.

Q: Can I stop taking this medicine when I feel better?

A: No, you must complete the full course as prescribed to prevent recurrence and resistance.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for quickstin 12.5mg dry syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of diarrhea.
    Fact: This medicine is only effective against specific bacterial infections. It does not work for viral or parasitic diarrhea.
  • Myth: You can stop taking this medicine as soon as you feel better.
    Fact: You must complete the full course as prescribed to prevent recurrence and resistance.
  • Myth: This medicine is safe for everyone.
    Fact: It should be used with caution in people with kidney problems and is not recommended for those allergic to polymyxins.

🔄 Alternative Options

Generic Alternatives

  • Colistin Sulphate oral suspension (generic)

Brand Alternatives

  • Walamycin Suspension

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Colistin Sulphate)","class":"Polymyxin antibiotic","route":"Oral","main_use":"Gastrointestinal infections","notes":"Poorly absorbed, local action."},{"medicine":"Polymyxin B","class":"Polymyxin antibiotic","route":"Oral/Topical","main_use":"Similar spectrum","notes":"Also poorly absorbed orally."},{"medicine":"Neomycin","class":"Aminoglycoside","route":"Oral","main_use":"Gut sterilization","notes":"Also poorly absorbed."}]

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