Scavista 12a Tablet: Complete Information
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, difficulty breathing
- Signs of liver injury: yellowing of eyes or skin, dark urine, severe abdominal pain
- Neurological symptoms: seizures, confusion, loss of coordination
- Severe skin rash with blistering or peeling
- Persistent vomiting or diarrhoea leading to dehydration
- Blood in stool or vomit
If experiencing severe symptoms, call emergency services immediately.
What is azplus syrup used for?
This medicine is a combination of ivermectin and albendazole used to treat certain parasitic worm infections. It works by paralysing and killing the worms, which are then expelled from the body. It should only be taken under medical supervision.
- Generic Name: Ivermectin (NA) + Albendazole (NA)
- Manufacturer: Cure Quick Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 azplus syrup के बारे में (Hindi Summary)
उपयोग: यह दवा इवरमेक्टिन और अल्बेंडाजोल का संयोजन है, जिसका उपयोग विभिन्न प्रकार के परजीवी कीड़ों के संक्रमण के इलाज के लिए किया जाता है। यह आंतों के कीड़ों, जैसे एस्केरियासिस, हुकवर्म और स्ट्रॉन्गीलॉइडियासिस के इलाज में प्रभावी है। यह दवा कीड़ों को पक्षाघात और मार देती है, जिससे वे शरीर से बाहर निकल जाते हैं। यह केवल डॉक्टर के पर्चे पर ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना और थकान शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में एलर्जी की प्रतिक्रिया, यकृत की क्षति और तंत्रिका संबंधी लक्षण शामिल हो सकते हैं। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे स्वयं न लें और न ही दूसरों के साथ साझा करें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं जो आप ले रहे हैं। इस दवा के सेवन के दौरान शराब से बचें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 azplus syrup Uses & Benefits
[{"condition":"Intestinal worm infections (ascariasis, hookworm, strongyloidiasis)","description":"This combination is effective against multiple types of intestinal nematodes, helping to eliminate the worms and relieve symptoms.","evidence":"Well-established"},{"condition":"Scabies","description":"Ivermectin is effective against scabies mites, and albendazole may provide additional antiparasitic coverage.","evidence":"Moderate"},{"condition":"Filariasis","description":"Used in mass drug administration programmes for lymphatic filariasis in some regions.","evidence":"Established in public health programmes"}]
Off-label uses: [{"condition":"Cutaneous larva migrans","description":"Sometimes used off-label for skin infestations caused by hookworm larvae.","evidence":"Limited"},{"condition":"Rosacea","description":"Ivermectin has been studied for rosacea, but the combination with albendazole is not standard.","evidence":"Limited"}]
Primary treatment for: Intestinal worm infections
Also treats: Scabies, Filariasis
📋 Drug Information
| Generic Name(s) | Ivermectin (NA) + Albendazole (NA) |
| Brand Name | azplus syrup |
| Manufacturer | Cure Quick Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. Ivermectin and albendazole are included in WHO essential medicines lists for specific parasitic infections, but combination use may vary. |
| ICMR Guideline | Not established from the available information. Consult local guidelines for parasitic infections. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antiparasitic drugs with complementary mechanisms. Ivermectin binds to glutamate-gated chloride channels in nerve and muscle cells of parasites, causing hyperpolarisation and paralysis, leading to death. Albendazole binds to tubulin, inhibiting microtubule polymerisation, which disrupts glucose uptake and energy production in worms, ultimately killing them. Together, they provide broad-spectrum activity against many helminths.
Mechanism Steps
💡 How to Take azplus syrup
Strength: Ivermectin (NA) + Albendazole (NA) immediate-release tablet. Strength not specified.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the specific infection, patient age, weight, and renal and hepatic function. For intestinal worm infections, a single dose is often used, but regimens may vary. Do not self-medicate. Follow your doctor's instructions exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Dose should be individualized by a clinician, considering renal and hepatic function. |
| Renal Impairment | No specific dose adjustment guidelines are established. Use with caution in patients with renal impairment. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | Not established from the available information. The maximum dose should be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of azplus syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Phenytoin | Moderate | |
| Ciclosporin | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
⚡ Moderate Interactions
- Anticonvulsants (e.g., phenytoin)
- Immunosuppressants (e.g., ciclosporin)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine as it may increase the risk of liver toxicity and worsen side effects such as dizziness and nausea.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ivermectin or albendazole","Pregnancy (especially first trimester)","Breastfeeding","Children under 2 years of age (unless specifically prescribed)","Severe liver disease"]
⚠️ Warnings & Precautions
["Use with caution in patients with liver impairment; dose adjustment may be needed.","Avoid in patients with known allergy to either component.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use in pregnancy unless clearly needed and advised by a doctor.","Avoid alcohol during treatment.","Inform your doctor if you have a history of seizures or neurological disorders."]
🤱 Lactation Safety
Ivermectin and albendazole are excreted in breast milk in small amounts. Breastfeeding is not recommended while taking this medicine unless advised by a doctor. Consult your healthcare provider.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhoea, dizziness, and in severe cases, neurological symptoms. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not self-medicate or share it with others. Inform your doctor about all other medicines you are taking, especially blood thinners, anticonvulsants, and immunosuppressants. Avoid alcohol while taking this medicine as it may increase the risk of liver problems. Use effective contraception during treatment if you are of childbearing age. Do not breastfeed while taking this medicine without consulting your doctor. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects such as dizziness and fatigue. Dose adjustment may be needed based on liver and kidney function. Close monitoring is advised.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the first trimester. If you are planning pregnancy, consult your doctor before taking this medicine. Use effective contraception during treatment.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with other medications used during surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. No specific precautions are established, but it is important for your healthcare provider to know your medication history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue after taking this medicine, avoid strenuous exercise or activities requiring alertness until you feel normal.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities with caution.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Complete the prescribed course to ensure the infection is fully treated.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically advised by a doctor. Prolonged use may increase the risk of liver toxicity and neurological side effects. Regular monitoring of liver function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Prevents reinfection and supports treatment.
Evidence: Well-establishedDepending on the specific infection, other medicines like mebendazole may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue with your regular dosing schedule as advised by your doctor. Check local customs regulations regarding prescription medicines before travelling.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The medicine starts working within hours, but you may see improvement in symptoms within a few days as the worms are expelled.
A: It is best taken with food to enhance absorption and reduce stomach upset.
A: Pediatric dosing is not established from available information. Consult a pediatrician.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any stomach problem.
Fact: It is specifically for parasitic worm infections and should not be used for general stomach issues. - Myth: It is safe to take without a prescription.
Fact: It is a prescription medicine and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Ivermectin + Albendazole combination (generic)
Brand Alternatives
- Scavista 12a Tablet