Excol Eye Ointment: A Comprehensive Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden vision loss or severe eye pain
- Swelling of face, lips, or throat
- Difficulty breathing
- Severe rash or hives
- Unusual tiredness, easy bruising, or bleeding
- Signs of infection that worsen or do not improve after 3 days
- Eye discharge that becomes thick and yellow-green
If experiencing severe symptoms, call emergency services immediately.
What is pychlor eye ointment used for?
This medicine is a combination antibiotic eye ointment used to treat bacterial eye infections. It contains Polymyxin B and Chloramphenicol, which work together to kill bacteria. Apply a small amount to the affected eye as directed by your doctor, usually 1-3 times daily. Do not use for more than 7 days without medical advice.
- Generic Name: Polymyxin B (5000IU) + Chloramphenicol (1mg)
- Manufacturer: Mac Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 pychlor eye ointment के बारे में (Hindi Summary)
उपयोग: यह दवा एक संयुक्त एंटीबायोटिक आई ऑइंटमेंट है जिसका उपयोग बैक्टीरियल आंखों के संक्रमण के इलाज के लिए किया जाता है। इसमें पॉलिमिक्सिन बी और क्लोरैम्फेनिकॉल होते हैं जो बैक्टीरिया को मारते हैं। यह आंखों की लालिमा, सूजन, डिस्चार्ज और जलन को कम करने में मदद करता है। इसे डॉक्टर के निर्देशानुसार प्रभावित आंख में लगाएं।
साइड इफेक्ट्स: आम दुष्प्रभावों में अस्थायी धुंधली दृष्टि, आंखों में जलन, खुजली या लालिमा शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, अस्थि मज्जा दमन या दृष्टि परिवर्तन हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर के निर्देशानुसार ही करें। लगाने से पहले और बाद में हाथ धोएं। ट्यूब की नोक को आंख या किसी सतह से न छुएं। कॉन्टैक्ट लेंस पहनने से पहले 15 मिनट प्रतीक्षा करें। निर्धारित अवधि से अधिक उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें।
💊 pychlor eye ointment Uses & Benefits
[{"condition":"Bacterial conjunctivitis","description":"Treats bacterial infection of the conjunctiva, reducing redness, discharge, and irritation.","evidence":"Well-established"},{"condition":"Blepharitis","description":"Helps control bacterial infection of the eyelid margins, reducing crusting and inflammation.","evidence":"Well-established"},{"condition":"Bacterial keratitis","description":"Used for superficial bacterial corneal infections under medical supervision.","evidence":"Well-established"},{"condition":"Bacterial corneal ulcers","description":"Adjunctive therapy for corneal ulcers caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Trachoma","description":"May be used in the treatment of trachoma, a chlamydial eye infection, as part of a broader treatment plan.","evidence":"Limited"}]
Off-label uses: [{"condition":"Prevention of infection after eye injury","description":"Sometimes prescribed off-label to prevent infection after minor ocular trauma or foreign body removal.","evidence":"Limited"},{"condition":"Post-operative prophylaxis","description":"Occasionally used after ocular surgery to prevent bacterial infection, though evidence is limited.","evidence":"Limited"}]
Primary treatment for: Bacterial eye infections
Also treats: Conjunctivitis, Blepharitis, Keratitis, Corneal ulcers
📋 Drug Information
| Generic Name(s) | Polymyxin B (5000IU) + Chloramphenicol (1mg) |
| Brand Name | pychlor eye ointment |
| Manufacturer | Mac Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL OTOLOGICALS |
| Action Class | |
| Route of Administration | Ophthalmic |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Keep the tube tightly closed when not in use. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise specified on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antibiotics with different mechanisms. Polymyxin B is a cyclic polypeptide that binds to the lipopolysaccharide component of the outer membrane of gram-negative bacteria. This binding disrupts the membrane integrity, leading to leakage of intracellular contents and bacterial cell death. Chloramphenicol is a broad-spectrum bacteriostatic antibiotic that inhibits bacterial protein synthesis by binding reversibly to the 50S ribosomal subunit, preventing peptide bond formation. The combination provides synergistic or additive activity against many ocular pathogens.
Mechanism Steps
💡 How to Take pychlor eye ointment
Strength: Eye ointment containing Polymyxin B 5000 IU and Chloramphenicol 1 mg per gram.
Dosage Information
| Adult Dosage | The usual adult dose is a small amount (about 1 cm) of ointment applied to the affected eye(s) one to three times daily, or as directed by your doctor. The frequency and duration depend on the type and severity of the infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients when used as directed. However, elderly patients may be more susceptible to side effects; use with caution. |
| Renal Impairment | No dose adjustment is typically required for topical ophthalmic use. However, if systemic absorption is a concern, consult a doctor. |
| Hepatic Impairment | No dose adjustment is typically required for topical ophthalmic use. However, if systemic absorption is a concern, consult a doctor. |
| Maximum Daily Dose | Not established from the available information. Use only as prescribed by your doctor. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of pychlor eye ointment
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | |
| Oral hypoglycemics | Moderate | |
| Other ophthalmic antibiotics | Major | |
| Bone marrow suppressants | Major |
🚨 Major Interactions
- Other ophthalmic antibiotics
- Bone marrow suppressants (e.g., chemotherapy, chloramphenicol systemic)
⚡ Moderate Interactions
- Warfarin
- Oral hypoglycemics
🍷 Alcohol Interaction
No known interaction with alcohol when used topically in the eye. However, alcohol may worsen underlying conditions or interact with other medications.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Polymyxin B, Chloramphenicol, or any component of the formulation","History of bone marrow suppression or blood dyscrasias","Viral, fungal, or mycobacterial eye infections (unless concurrent appropriate therapy)","Perforated eardrum (if used in ear, though this is an eye ointment)"]
⚠️ Warnings & Precautions
["Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","Do not use for more than 7 days without consulting a doctor.","Avoid touching the tip of the tube to the eye or any surface to prevent contamination.","If symptoms worsen or do not improve within 2-3 days, discontinue and consult a doctor.","Use with caution in patients with a history of blood disorders.","Not for injection or oral use.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk in significant amounts. Consult your doctor before use if breastfeeding.
💊 Overdose Management
Overdose is unlikely with topical ophthalmic use. If accidental ingestion occurs, seek medical attention immediately. Symptoms of systemic chloramphenicol overdose may include nausea, vomiting, and bone marrow suppression. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Use this medicine exactly as prescribed by your doctor. Wash your hands thoroughly before and after applying the ointment. Avoid touching the tip of the tube to your eye or any surface to prevent contamination. Do not share your eye ointment with anyone else. If you wear contact lenses, remove them before application and wait at least 15 minutes before reinserting. Do not use this medicine for longer than prescribed, as prolonged use may cause unwanted effects. If your symptoms do not improve within a few days or worsen, contact your doctor. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep this medicine out of reach of children. Store as directed on the label.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects. Use with caution and monitor for any unusual symptoms.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. It should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed after eye surgery to prevent infection. Use exactly as directed by your surgeon.
🦷 Dental Procedures
No specific considerations for dental procedures. However, inform your dentist about all medications you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions while using this medicine. However, if you experience blurred vision after application, avoid activities that require clear vision until it clears.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause temporary blurred vision after application. Avoid driving or operating heavy machinery until your vision is clear. Otherwise, it should not significantly impact your daily activities.
🛑 When to Stop This Medicine
Stop using this medicine if you experience a serious allergic reaction, or if your doctor advises discontinuation. Do not stop prematurely even if symptoms improve, as this may lead to recurrence. Consult your doctor before stopping.
📅 Long-Term Use Effects
Prolonged use of this medicine may lead to antibiotic resistance, secondary fungal infections, or superinfection with resistant bacteria. It should only be used for the prescribed duration. Long-term use is not recommended unless under strict medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help relieve discomfort and loosen crusts in blepharitis.
Evidence: Well-establishedRegular cleaning of eyelids can prevent recurrence of blepharitis.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interaction with vaccines. However, if you have an active eye infection, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue your regular dosing schedule as close as possible. Keep the tube tightly closed and avoid exposing it to direct sunlight.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling relief within 1-2 days, but complete resolution may take up to a week depending on the infection.
A: No, this medicine is only effective against bacterial infections. Viral infections require different treatment.
A: Pediatric dosing is not established. Consult a pediatrician before use in children.
A: Remove contact lenses before applying the ointment and wait at least 15 minutes before reinserting.
A: Apply as soon as you remember, but if it's almost time for the next dose, skip the missed dose and continue your regular schedule.
🤔 Common Patient Concerns
🔄 Substitutes for pychlor eye ointment
View AllAlternative brands with exact same active ingredient:
-
pychlor eye/ear dropsMac Laboratories Ltd ₹17.58 2.1% COSTLIER
-
poly c eye ointmentKaizen Pharmaceuticals Pvt Ltd ₹25.37 47.4% COSTLIER
-
takchlor eye/ear dropsPharmtak Ophtalmics India Pvt Ltd ₹40.00 132.4% COSTLIER
-
takchlor eye ointmentPharmtak Ophtalmics India Pvt Ltd ₹60.94 254.1% COSTLIER
-
excol eye ointmentNovogen Captab ₹75.00 335.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any eye infection.
Fact: It is only effective against bacterial infections. Viral or fungal infections require different treatments. - Myth: It is safe to use for long periods.
Fact: Prolonged use can lead to antibiotic resistance and secondary infections. Use only as prescribed. - Myth: You can stop using it as soon as symptoms improve.
Fact: You should complete the full course as prescribed to prevent recurrence and resistance.
🔄 Alternative Options
Generic Alternatives
- Polymyxin B + Chloramphenicol ophthalmic ointment
Brand Alternatives
- Excol Eye Ointment