eyclor eye drop - Polymyxin B (5000IU) + Chloramphenicol (10mg) medicine

Eyclor Eye Drop: Complete Medicine Guide

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🏭 Ultramark Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden vision loss or severe eye pain
  • Swelling of the face, lips, or throat
  • Signs of bone marrow suppression: unusual tiredness, easy bruising, or frequent infections
  • Severe allergic reaction with rash, itching, or difficulty breathing
  • No improvement or worsening of symptoms after 7 days of use
  • Development of new eye symptoms such as floaters or flashes of light

If experiencing severe symptoms, call emergency services immediately.

What is eyclor eye drop used for?

This medicine is a combination antibiotic eye drop containing Polymyxin B and Chloramphenicol. It is used to treat bacterial eye infections such as conjunctivitis. It works by killing bacteria and stopping their growth. Use it exactly as prescribed by your doctor.

  • Generic Name: Polymyxin B (5000IU) + Chloramphenicol (10mg)
  • Manufacturer: Ultramark Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 eyclor eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा आंखों के बैक्टीरियल संक्रमण जैसे कंजंक्टिवाइटिस (आंख आना), ब्लेफेराइटिस (पलकों की सूजन), और केराटाइटिस (कॉर्निया का संक्रमण) के इलाज के लिए इस्तेमाल की जाती है। यह पॉलीमिक्सिन बी और क्लोरैम्फेनिकॉल का संयोजन है, जो बैक्टीरिया को मारता है और उनकी वृद्धि को रोकता है। इसका उपयोग डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में अस्थायी धुंधली दृष्टि, हल्की जलन या खुजली शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। दुर्लभ मामलों में एलर्जी, आंखों में सूजन, या गंभीर रक्त विकार हो सकते हैं। यदि आपको असामान्य थकान, आसान चोट लगना, या संक्रमण के लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को अपनी एलर्जी और चिकित्सीय स्थिति के बारे में बताएं। निर्धारित अवधि से अधिक इसका उपयोग न करें। ड्रॉपर की नोक को आंख या किसी सतह से न छुएं। कॉन्टैक्ट लेंस पहनने से पहले डॉक्टर से सलाह लें। इस दवा को दूसरों के साथ साझा न करें। यदि लक्षण ठीक न हों तो डॉक्टर से मिलें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 eyclor eye drop Uses & Benefits

[{"condition":"Bacterial conjunctivitis","description":"This medicine is effective against a wide range of bacteria causing conjunctivitis, reducing redness, discharge, and irritation.","evidence":"Well-established"},{"condition":"Blepharitis","description":"It helps treat bacterial infection of the eyelids, reducing inflammation and crusting.","evidence":"Well-established"},{"condition":"Keratitis","description":"Used for bacterial keratitis, though severe cases may require additional systemic therapy.","evidence":"Moderate"},{"condition":"Dacryocystitis","description":"May be used as adjunctive therapy for infection of the lacrimal sac.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of infection after eye surgery","description":"Sometimes prescribed prophylactically after ocular procedures, though evidence is limited.","evidence":"Limited"},{"condition":"Neonatal conjunctivitis prophylaxis","description":"Not routinely recommended due to resistance and safety concerns.","evidence":"Limited"}]

Primary treatment for: Bacterial conjunctivitis

Also treats: Blepharitis, Keratitis, Dacryocystitis

📋 Drug Information

Generic Name(s)Polymyxin B (5000IU) + Chloramphenicol (10mg)
Brand Nameeyclor eye drop
ManufacturerUltramark Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL OTOLOGICALS
Action Class
Route of AdministrationOphthalmic
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always wash your hands before and after applying this medicine to prevent contamination.
2
Do not touch the dropper tip to your eye or any surface, as this can introduce bacteria.
3
If you wear contact lenses, remove them before application and wait at least 15 minutes before reinserting.
4
Complete the full course of treatment even if symptoms improve, to prevent recurrence and resistance.
5
If you are using other eye drops, wait at least 5-10 minutes between applications to avoid washing out the medicine.
6
Report any signs of allergic reaction such as itching, swelling, or rash to your doctor immediately.
7
Do not use this medicine for longer than prescribed, as prolonged use can lead to fungal infections or resistance.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Red eye with discharge
This medicine is commonly prescribed for bacterial conjunctivitis.
Likely Use
❌
Itchy, watery eyes without discharge
This medicine is not effective for allergic conjunctivitis.
Not Primary
❌
Eye pain with blurred vision
This may indicate a more serious condition; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption of Polymyxin B and Chloramphenicol after topical ocular administration is minimal. However, some absorption can occur through the conjunctiva and nasal mucosa, especially if the eye is inflamed or if the drops are used excessively.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismChloramphenicol is metabolized in the liver primarily by glucuronidation. Polymyxin B is not significantly metabolized.
Half-LifeNot established from the available information.
ExcretionChloramphenicol and its metabolites are excreted mainly in urine. Polymyxin B is excreted primarily in urine unchanged.
BioavailabilitySystemic bioavailability following ocular administration is very low, typically less than 5%.
Onset of ActionSymptomatic relief may begin within 24 to 48 hours of starting therapy.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect lasts for several hours after each dose; however, the dosing frequency is determined by the prescribed regimen.

How It Works

This medicine combines two antibiotics with complementary mechanisms. Polymyxin B binds to the lipopolysaccharide component of the outer membrane of Gram-negative bacteria, disrupting membrane integrity and causing leakage of cellular contents, leading to bacterial death. Chloramphenicol is a broad-spectrum bacteriostatic antibiotic that penetrates bacterial cells and binds reversibly to the 50S ribosomal subunit, inhibiting peptidyl transferase activity and thereby blocking protein synthesis. The combination provides synergistic action against many ocular pathogens.

Mechanism Steps

1
Polymyxin B binds to bacterial membrane: Polymyxin B attaches to the lipopolysaccharide layer of Gram-negative bacteria, disrupting the outer membrane.
2
Membrane disruption: This binding increases permeability, causing leakage of essential ions and molecules, leading to cell death.
3
Chloramphenicol enters bacteria: Chloramphenicol diffuses through the bacterial cell membrane and binds to the 50S ribosomal subunit.
4
Inhibition of protein synthesis: It blocks the peptidyl transferase reaction, preventing the formation of peptide bonds and halting protein production.
5
Bacterial growth inhibition: Without essential proteins, bacteria cannot multiply, and the immune system clears the infection.

💡 How to Take eyclor eye drop

Strength: Polymyxin B 5000 IU + Chloramphenicol 10 mg per mL

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently before use.
3Tilt your head back and pull down your lower eyelid to form a pouch.
4Hold the dropper above the eye and squeeze one drop into the pouch.
5Close your eye gently and press the inner corner with your finger for 1-2 minutes.
6Repeat for the other eye if needed.
7Replace the cap tightly after use.

Dosage Information

Adult DosageThe usual adult dose is one to two drops in the affected eye(s) every 4 to 6 hours, or as directed by your doctor. For severe infections, your doctor may recommend more frequent dosing initially. The dose and duration must be individualized by a qualified clinician based on the severity of infection, response to treatment, and renal/hepatic function. Always complete the full course as prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may use this medicine as prescribed, but they should be monitored for any signs of systemic absorption or adverse effects.
Renal ImpairmentNo specific dosage adjustment is required for topical ocular use, but caution is advised in patients with severe renal impairment due to potential systemic absorption.
Hepatic ImpairmentNo specific dosage adjustment is required for topical ocular use, but caution is advised in patients with severe hepatic impairment.
Maximum Daily DoseNot established from the available information.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of eyclor eye drop

✅ Common Side Effects

Temporary blurred vision (Common (5-10%))
Wait until vision clears before driving or operating machinery.
Mild stinging or burning (Common (5-10%))
Usually resolves quickly; if persistent, consult your doctor.
Eye irritation (Common (5-10%))
Avoid rubbing eyes; if irritation worsens, seek medical advice.

🚨 Serious Side Effects

Allergic reaction (itching, swelling, rash) (Rare (<0.1%))
Discontinue use and seek immediate medical attention.
Bone marrow suppression (rare with topical use) (Very rare (<0.01%))
Report unusual fatigue, bruising, or infections to your doctor immediately.
Optic neuritis (Very rare (<0.01%))
Seek medical attention if you experience vision loss or eye pain.

⚠️ Rare Side Effects

Peripheral neuropathy
Consult a neurologist if you experience numbness or tingling.
Superinfection (fungal or resistant bacterial)
Contact your doctor if new symptoms appear.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate
Phenytoin Moderate
Other eye drops Major

🚨 Major Interactions

  • Other ophthalmic antibiotics
  • Bone marrow suppressants (e.g., chemotherapy)

⚡ Moderate Interactions

  • Warfarin
  • Phenytoin

🍷 Alcohol Interaction

No known interaction with alcohol when used topically in the eye. However, excessive alcohol consumption may impair immune response and delay healing.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Polymyxin B, Chloramphenicol, or any component","History of bone marrow suppression","Viral, fungal, or untreated purulent ocular infections","Use in children under 2 years (unless directed by a doctor)"]

⚠️ Warnings & Precautions

["Prolonged use may lead to overgrowth of non-susceptible organisms.","Do not use if the solution is cloudy or discolored.","Avoid contact with soft contact lenses.","Do not exceed the prescribed dose or duration.","Consult a doctor if symptoms persist after 7 days."]

🤱 Lactation Safety

Chloramphenicol passes into breast milk. Use with caution during breastfeeding; consult your doctor.

💊 Overdose Management

Overdose with this medicine is unlikely due to its topical nature. If accidental ingestion occurs, seek medical attention. In case of excessive eye application, rinse the eye with water and consult a doctor.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you are allergic to Polymyxin B, Chloramphenicol, or any other antibiotics. Do not use this medicine for more than the prescribed duration, as prolonged use may lead to fungal overgrowth or antibiotic resistance. Avoid touching the dropper tip to your eye or any surface to prevent contamination. If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting. Do not share this medicine with others. If your symptoms do not improve within a few days or worsen, contact your doctor. Pregnant and breastfeeding women should consult their doctor before use. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects. Use with caution and monitor for any unusual symptoms.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are planning pregnancy. Chloramphenicol may not be safe during pregnancy.

🏥 Post-Surgery Considerations

If you have had eye surgery, use this medicine only if prescribed by your surgeon. Follow their instructions carefully.

🦷 Dental Procedures

No specific considerations for dental procedures, but inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hand hygiene to prevent spreading infection.
🥗
Avoid touching or rubbing your eyes.
😴
Do not share towels or pillows with others during infection.
💧
Follow a healthy diet rich in vitamins A and C to support eye health.
🧘
Get adequate rest to help your body fight infection.
🌞
Avoid wearing eye makeup until the infection clears.

🏋️ Exercise Considerations

No specific exercise restrictions, but avoid swimming or water sports until the infection resolves to prevent contamination.

🥗 Diet Recommendations

Include foods rich in vitamin A (carrots, spinach) for eye health.
Stay hydrated to maintain tear production.
Avoid excessive caffeine and alcohol which can dehydrate.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision after application. Wait until vision clears before driving or operating machinery. You can continue normal activities, but avoid touching your eyes.

🛑 When to Stop This Medicine

Stop using this medicine only after completing the prescribed course or as directed by your doctor. If you experience serious side effects, stop immediately and seek medical advice.

📅 Long-Term Use Effects

Prolonged use of this medicine can lead to antibiotic resistance, fungal overgrowth, and rarely bone marrow suppression. It should only be used for the prescribed duration. Regular follow-up with your doctor is advised if extended therapy is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Warm compresses

Can help relieve discomfort and loosen crusts in blepharitis.

Evidence: Well-established
Eyelid hygiene

Regular cleaning of eyelids can prevent recurrence of blepharitis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. However, if you are scheduled for vaccination, inform your doctor about this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, keep it in its original packaging with the prescription label. Carry a copy of your prescription to avoid issues at customs. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue your regular dosing schedule as prescribed; consult your doctor if adjustments are needed.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with bacterial conjunctivitis
She was prescribed this medicine for redness and discharge in her right eye. She applied the drops as directed and noticed improvement within two days. She completed the full course and the infection cleared completely.
💡 Lesson: Consistent use and completing the full course are key to resolving bacterial eye infections.
👤 A 60-year-old man with blepharitis
He used this medicine for eyelid inflammation. He experienced mild stinging initially but it subsided. He was advised to maintain eyelid hygiene along with the drops, which helped prevent recurrence.
💡 Lesson: Combining medicine with good eyelid hygiene improves outcomes in blepharitis.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief within 24-48 hours, but complete the full course as prescribed.

Q: Can I use this medicine for viral conjunctivitis?

A: No, this medicine is only effective against bacterial infections. Viral conjunctivitis requires different treatment.

Q: Is it safe for children?

A: It is generally not recommended for children under 2 years unless directed by a doctor. Consult a pediatrician.

Q: What if I accidentally swallow the drops?

A: Seek medical attention immediately, as chloramphenicol can be harmful if ingested.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine for viral eye infection?
  • How long can I use this medicine safely?
  • Will it affect my vision permanently?
  • Can I wear contact lenses while using this medicine?
  • Is it safe to use during pregnancy?
  • What should I do if I miss a dose?

🔄 Substitutes for eyclor eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: It can be used for any red eye.
    Fact: It is only effective for bacterial infections; viral or allergic conjunctivitis requires different treatment.
  • Myth: It is safe to use for long periods.
    Fact: Prolonged use can lead to resistance and side effects; use only as prescribed.

🔄 Alternative Options

Generic Alternatives

  • Polymyxin B + Chloramphenicol eye drops

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Polymyxin B + Chloramphenicol","uses":"Bacterial eye infections","notes":"Broad-spectrum, but chloramphenicol carries rare risk of bone marrow suppression."},{"medicine":"Polymyxin B + Neomycin + Gramicidin","composition":"Polymyxin B + Neomycin + Gramicidin","uses":"Bacterial eye infections","notes":"Neomycin may cause allergic reactions."}]

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