prizide mv 0.2mg/500mg/80mg tablet - Voglibose (0.2mg) + Metformin (500mg) medicine

Eldozide V Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Primus Remedies Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for individual components; limited for the specific combination.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Rapid breathing or shortness of breath
  • Severe muscle pain or cramps
  • Extreme tiredness or weakness
  • Stomach pain with nausea or vomiting
  • Confusion or dizziness
  • Yellowing of skin or eyes
  • Decreased urine output
  • Severe hypoglycemia symptoms (shakiness, sweating, confusion)

If experiencing severe symptoms, call emergency services immediately.

What is prizide mv 0.2mg/500mg/80mg tablet used for?

This medicine is a combination of Voglibose and Metformin used to treat type 2 diabetes. It lowers blood sugar by slowing carbohydrate absorption and reducing glucose production in the liver. It is taken orally with meals.

  • Generic Name: Voglibose (0.2mg) + Metformin (500mg)
  • Manufacturer: Primus Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 prizide mv 0.2mg/500mg/80mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा वोग्लिबोस और मेटफॉर्मिन का संयोजन है, जिसका उपयोग टाइप 2 डायबिटीज (मधुमेह) के इलाज में किया जाता है। यह भोजन के बाद ब्लड शुगर को बढ़ने से रोकती है और लीवर में ग्लूकोज बनने को कम करती है। इसे हमेशा भोजन के साथ लेना चाहिए। यह दवा डॉक्टर की सलाह के बिना बंद नहीं करनी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में पेट में गैस, सूजन, दस्त, मतली और पेट में असहजता शामिल हैं। गंभीर लेकिन दुर्लभ दुष्प्रभावों में लैक्टिक एसिडोसिस (तेज सांस, मांसपेशियों में दर्द, अत्यधिक थकान) और गंभीर हाइपोग्लाइसीमिया हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को हमेशा भोजन के पहले निवाले के साथ लें। खाली पेट न लें। अत्यधिक शराब से बचें। अपने ब्लड शुगर की नियमित जांच करें। किडनी और लीवर की जांच समय-समय पर कराते रहें। डॉक्टर की सलाह के बिना दवा की खुराक न बदलें और न ही बंद करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 prizide mv 0.2mg/500mg/80mg tablet Uses & Benefits

[{"condition":"Type 2 diabetes mellitus","description":"Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes, particularly to target postprandial glucose excursions.","evidence":"Well-established"},{"condition":"Postprandial hyperglycemia","description":"Voglibose specifically reduces the spike in blood sugar after meals by delaying carbohydrate absorption.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Prediabetes","description":"Sometimes considered off-label to delay progression to diabetes, but not approved for this use.","evidence":"Limited"},{"condition":"Polycystic ovary syndrome (PCOS)","description":"Metformin component may be used off-label for insulin resistance in PCOS, but the combination is not standard.","evidence":"Limited"}]

Primary treatment for: Type 2 diabetes mellitus

Also treats: Postprandial hyperglycemia, Insulin resistance

📋 Drug Information

Generic Name(s)Voglibose (0.2mg) + Metformin (500mg)
Brand Nameprizide mv 0.2mg/500mg/80mg tablet
ManufacturerPrimus Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with the first bite of a meal to reduce stomach upset and improve effectiveness.
2
Never skip meals while on this medicine, especially if you also take insulin or sulfonylureas.
3
Monitor your blood sugar regularly and keep a log to share with your doctor.
4
Stay well hydrated and avoid excessive alcohol consumption.
5
Report any symptoms of lactic acidosis (rapid breathing, muscle pain, extreme fatigue) immediately.
6
Get your kidney and liver function tested at least once a year.
7
Do not stop or change the dose without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood sugar after meals
This medicine is commonly prescribed for this.
Likely Use
✅
Type 2 diabetes
This medicine is used to manage type 2 diabetes.
Likely Use
❌
Type 1 diabetes
This medicine is not suitable for type 1 diabetes.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionVoglibose is poorly absorbed from the gastrointestinal tract, with less than 2% of an oral dose reaching systemic circulation; it acts locally in the gut. Metformin is absorbed primarily from the small intestine, with bioavailability of about 50-60% under fasting conditions. Food decreases the rate and extent of metformin absorption slightly but does not significantly affect clinical efficacy.
DistributionVoglibose has negligible systemic distribution due to minimal absorption. Metformin is rapidly distributed to body tissues, including liver, kidney, and gastrointestinal tract; it does not bind to plasma proteins significantly and has a volume of distribution of about 654 L.
Protein BindingVoglibose: Not established from the available information. Metformin: Negligible plasma protein binding.
MetabolismVoglibose is not significantly metabolized; it is excreted unchanged in feces and urine. Metformin is not metabolized in humans and is excreted unchanged by the kidneys.
Half-LifeVoglibose: Not established from the available information. Metformin: Approximately 6.2 hours in plasma and about 17.6 hours in whole blood.
ExcretionVoglibose is excreted mainly in feces (about 90%) and urine (about 10%). Metformin is excreted unchanged in urine via active tubular secretion; about 90% of an absorbed dose is eliminated within 24 hours.
BioavailabilityVoglibose: Less than 2% systemic bioavailability. Metformin: Approximately 50-60% under fasting conditions.
Onset of ActionVoglibose begins to reduce postprandial glucose within 30-60 minutes after a meal. Metformin's full effect on glycemic control may take several days to weeks.
Peak Plasma TimeVoglibose: Not established from the available information. Metformin: 2-3 hours after an immediate-release dose.
Duration of ActionVoglibose: Approximately 4-6 hours per dose. Metformin: Glucose-lowering effect persists throughout the dosing interval, typically 12 hours for immediate-release formulations.

How It Works

This medicine combines two oral antidiabetic agents with complementary mechanisms. Voglibose is a competitive inhibitor of alpha-glucosidase enzymes (maltase, sucrase, glucoamylase) in the brush border of the small intestine, which delays the breakdown of complex carbohydrates into monosaccharides and reduces postprandial glucose absorption. Metformin is a biguanide that decreases hepatic gluconeogenesis and glycogenolysis, reduces intestinal glucose absorption, and enhances peripheral insulin sensitivity by increasing insulin-mediated glucose uptake in skeletal muscle and adipose tissue. The combination addresses both fasting and postprandial hyperglycemia.

Mechanism Steps

1
Inhibition of alpha-glucosidase: Voglibose competitively inhibits alpha-glucosidase enzymes in the small intestine, delaying the digestion of carbohydrates into simple sugars.
2
Reduced postprandial glucose absorption: Because carbohydrates are broken down more slowly, glucose enters the bloodstream gradually, preventing sharp post-meal spikes.
3
Suppression of hepatic glucose production: Metformin decreases gluconeogenesis and glycogenolysis in the liver, reducing the amount of glucose released into the blood.
4
Improved insulin sensitivity: Metformin enhances insulin-mediated glucose uptake in skeletal muscle and fat cells, improving overall glucose utilization.
5
Combined glycemic control: The two agents work together to lower both fasting and post-meal blood sugar levels, improving HbA1c.

💡 How to Take prizide mv 0.2mg/500mg/80mg tablet

Strength: Voglibose 0.2 mg + Metformin 500 mg immediate-release tablet

1Take this medicine orally with a full glass of water.
2Take it with the first bite of each main meal to reduce gastrointestinal side effects and improve efficacy.
3Swallow the tablet whole; do not crush or chew.
4Do not take it on an empty stomach.
5Follow your doctor's prescribed dosing schedule exactly.

Dosage Information

Adult DosageThe usual starting dose is one tablet taken orally with meals, typically once or twice daily, depending on the prescribed regimen. The dose may be adjusted by your doctor based on blood sugar levels, kidney function, and tolerability. The maximum recommended dose of metformin is 2000 mg per day, and voglibose is usually limited to 0.6 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require lower doses due to reduced renal function. Regular monitoring of kidney function is advised. Dose must be individualized by a qualified clinician.
Renal ImpairmentMetformin is contraindicated in severe renal impairment (eGFR <30 mL/min/1.73 m²). In mild to moderate renal impairment, dose reduction or discontinuation may be necessary. Voglibose does not require renal dose adjustment. Consult your doctor for personalized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Metformin is contraindicated in severe hepatic impairment due to increased risk of lactic acidosis. Dose adjustment may be needed. Consult your doctor.
Maximum Daily DoseThe maximum daily dose of metformin is 2000 mg, and voglibose is 0.6 mg. However, the exact maximum for this combination depends on the prescribed regimen and clinical judgment.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with the first bite of food
Enhances efficacy of Voglibose and reduces gastrointestinal side effects.
Alcohol
Avoid excessive intake
Increases risk of lactic acidosis and hypoglycemia.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose with your next meal as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of prizide mv 0.2mg/500mg/80mg tablet

✅ Common Side Effects

Flatulence (Common (10-30%))
Usually decreases with continued use. Avoid excessive gas-producing foods.
Abdominal bloating (Common (10-20%))
Take with meals and eat smaller portions. Consult doctor if persistent.
Diarrhea (Common (5-15%))
Stay hydrated. If severe or persistent, contact your doctor.
Nausea (Common (5-10%))
Take with food. Usually resolves over time.
Metallic taste (Uncommon (1-5%))
Usually temporary. Chewing sugar-free gum may help.

🚨 Serious Side Effects

Lactic acidosis (Rare (<0.1%))
Seek emergency care if you experience rapid breathing, muscle pain, extreme fatigue, or stomach discomfort.
Severe hypoglycemia (Rare when used alone; higher with insulin/sulfonylureas)
Recognize symptoms like shakiness, sweating, confusion, and rapid heartbeat. Treat with fast-acting sugar and seek medical help.
Hepatotoxicity (Very rare (<0.01%))
Report yellowing of eyes or skin, dark urine, or right upper abdominal pain immediately.

⚠️ Rare Side Effects

Intestinal obstruction-like symptoms
Seek immediate medical attention for severe constipation, vomiting, or abdominal distension.
Severe skin reactions (e.g., Stevens-Johnson syndrome)
Stop the medicine and seek emergency care if you develop rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Iodinated contrast media Major
Alcohol Major
Sulfonylureas Major
Insulin Major
Diuretics Moderate
Corticosteroids Moderate
Cationic drugs Moderate
Acarbose Minor
Thiazolidinediones Minor
Beta-blockers Minor

🚨 Major Interactions

  • Iodinated contrast media
  • Alcohol
  • Sulfonylureas (e.g., glimepiride)
  • Insulin

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, ranitidine, triamterene, vancomycin)

🍷 Alcohol Interaction

Alcohol should be avoided or limited while taking this medicine because it increases the risk of lactic acidosis (a rare but serious complication of metformin) and can cause unpredictable drops in blood sugar. If you choose to drink, do so in moderation and never on an empty stomach, and inform your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Lactic acidosis is a rare but serious complication; discontinue and seek immediate medical help if suspected.","Avoid excessive alcohol intake while on this medicine.","Temporarily discontinue before iodinated contrast imaging procedures.","Monitor renal function regularly, especially in elderly patients.","Use with caution in patients with heart failure, especially unstable or acute heart failure.","May cause hypoglycemia when combined with insulin or sulfonylureas; monitor blood glucose closely.","Not recommended for use in children.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Metformin is excreted in breast milk in small amounts and is generally considered compatible with breastfeeding. Voglibose: Not established from the available information. Consult your doctor before breastfeeding while on this medicine.

💊 Overdose Management

Overdose may cause hypoglycemia, lactic acidosis, or severe gastrointestinal symptoms. Seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of blood glucose, renal function, and acid-base balance. Hemodialysis may be considered for metformin overdose in severe cases.

⏰ Missed Dose

If you miss a dose, take it with your next meal if it is within a short time. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine with the first bite of each main meal to reduce gastrointestinal side effects and optimize effectiveness. Never skip meals while on this medicine, as it can increase the risk of low blood sugar, especially if you also take sulfonylureas or insulin. Stay well hydrated, avoid excessive alcohol, and inform your doctor about all other medicines, supplements, or herbal products you use. Monitor your blood sugar regularly as advised. Do not stop or change the dose without consulting your clinician. If you develop severe abdominal pain, rapid breathing, or extreme weakness, seek emergency medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of renal impairment and lactic acidosis. Regular monitoring of kidney function is essential. Dose adjustments may be needed. Consult your doctor.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before conceiving. Metformin may be continued under medical supervision, but Voglibose is not recommended due to lack of safety data. Your treatment plan may need to be adjusted.

🏥 Post-Surgery Considerations

This medicine may need to be temporarily discontinued before surgery, especially if you will be fasting or undergoing procedures with contrast media. Follow your surgeon's and doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. If you are scheduled for a procedure requiring fasting, consult your doctor about dose adjustments to avoid hypoglycemia.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to improve insulin sensitivity.
🥗
Engage in regular physical activity, such as brisk walking or swimming.
😴
Eat a balanced diet rich in fiber, lean protein, and healthy fats.
💧
Limit intake of refined sugars and processed foods.
🧘
Monitor your blood sugar regularly as advised.
🌞
Get adequate sleep and manage stress.

🏋️ Exercise Considerations

Exercise is encouraged as part of diabetes management, but monitor your blood sugar before and after exercise, especially if you take other glucose-lowering medicines. Carry a fast-acting sugar source in case of hypoglycemia. Stay hydrated.

🥗 Diet Recommendations

Include high-fiber foods like whole grains, vegetables, and legumes.
Choose lean proteins such as fish, chicken, and tofu.
Limit sugary drinks and snacks.
Eat small, frequent meals to help control blood sugar.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine may cause hypoglycemia, especially when combined with other antidiabetic drugs. If you experience symptoms like dizziness or shakiness, avoid driving or operating heavy machinery until you feel better. Otherwise, it generally does not interfere with daily activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your blood sugar is well-controlled, your doctor may adjust or discontinue it. Always seek medical advice before stopping.

📅 Long-Term Use Effects

Long-term use of this medicine requires regular monitoring of blood sugar, kidney function, liver function, and vitamin B12 levels. Metformin may cause vitamin B12 deficiency over time. The combination helps maintain glycemic control but does not cure diabetes. Lifestyle modifications remain essential.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet and exercise are foundational for managing type 2 diabetes and can complement medicine.

Evidence: Well-established
Other oral antidiabetic agents

Depending on your condition, your doctor may prescribe other classes like DPP-4 inhibitors, SGLT2 inhibitors, or sulfonylureas.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

People with diabetes are advised to receive routine vaccinations, including influenza and pneumococcal vaccines. There are no specific interactions between this medicine and vaccines. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. If traveling across time zones, adjust dosing times gradually in consultation with your doctor. Store at room temperature and avoid direct sunlight. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with type 2 diabetes and poor post-meal sugar control
He was prescribed this medicine to be taken twice daily with meals. After 4 weeks, his post-meal sugar levels improved significantly, and he experienced only mild bloating initially, which resolved. He emphasized that taking it with food was key to tolerating it.
💡 Lesson: Taking this medicine with meals improves tolerability and effectiveness.
👤 A 60-year-old woman with type 2 diabetes and mild kidney impairment
Her doctor started her on this medicine with careful monitoring of kidney function. She was advised to avoid alcohol and stay hydrated. Her blood sugar improved, and regular kidney tests remained stable.
💡 Lesson: Regular monitoring of kidney function is essential, especially in older adults.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Voglibose starts reducing post-meal sugar within 30-60 minutes, while Metformin's full effect may take several days to weeks.

Q: Can I take this medicine on an empty stomach?

A: No, it should always be taken with meals to reduce side effects and improve effectiveness.

Q: What should I do if I miss a dose?

A: If you remember within a short time, take it with your next meal. If it's almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double dose.

Q: Is this medicine safe for my kidneys?

A: Metformin can accumulate in kidney impairment and increase the risk of lactic acidosis. Regular monitoring of kidney function is essential. It is contraindicated in severe renal impairment.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for prizide mv 0.2mg/500mg/80mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure diabetes.
    Fact: This medicine helps manage blood sugar but does not cure diabetes. Lifestyle changes and ongoing treatment are essential.
  • Myth: You can stop taking this medicine once your sugar levels are normal.
    Fact: Normal sugar levels are often due to the medicine. Stopping without medical advice can cause sugar levels to rise again.
  • Myth: This medicine causes weight gain.
    Fact: Metformin is weight-neutral or may cause slight weight loss. Voglibose does not cause weight gain.

🔄 Alternative Options

Generic Alternatives

  • Voglibose + Metformin generic tablets

Brand Alternatives

  • Eldozide V Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Voglibose 0.2 mg + Metformin 500 mg","key_feature":"Targets both fasting and postprandial glucose"},{"medicine":"Metformin alone","composition":"Metformin 500 mg","key_feature":"Primarily lowers fasting glucose; less effect on postprandial spikes"},{"medicine":"Voglibose alone","composition":"Voglibose 0.2 mg","key_feature":"Primarily lowers postprandial glucose; minimal effect on fasting glucose"}]

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