apyridine p 100mg/325mg tablet
What is apyridine p 100mg/325mg tablet used for?
Apyridine P 100mg/325mg Tablet (Flupirtine + Paracetamol) is used to treat PAIN ANALGESICS. It contains Flupirtine (100mg) + Paracetamol (325mg), which Flupirtine: Selective neuronal potassium channel opener, stabilizes resting memb. Always consult your doctor before use. Take as prescribed.
- Generic Name: Flupirtine + Paracetamol
- Manufacturer: Primus Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ apyridine p 100mg/325mg tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Flupirtine + Paracetamol |
| Brand Name | Apyridine P 100mg/325mg Tablet |
| Manufacturer | Primus Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Pain Analgesics |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Flupirtine: Selective neuronal potassium channel opener, stabilizes resting membrane potential, inhibits NMDA receptor indirectly; Paracetamol: Inhibits COX-1 and COX-2 in CNS, activates descending serotonergic pathways.
Mechanism Steps
๐ก How to Take apyridine p 100mg/325mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of apyridine p 100mg/325mg tablet
โ Common Side Effects
- Nausea
- Dizziness
- Drowsiness
- Constipation
- Dry mouth
๐จ Serious Side Effects
- Hepatotoxicity
- Stevens-Johnson syndrome
- QT prolongation
- Seizures
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Anaphylaxis
- Hallucinations
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Carbamazepine | Major | Reduced flupirtine efficacy, increased hepatotoxicity |
| Alcohol | Major | Increased hepatotoxicity risk |
| Oral contraceptives | Moderate | Reduced analgesic effect of paracetamol |
| Metoclopramide | Minor | Increased absorption rate of paracetamol |
๐จ Major Interactions
- Warfarin
- Carbamazepine
- Phenytoin
- Rifampin
- Alcohol (chronic use)
โก Moderate Interactions
- Oral contraceptives
- Chloramphenicol
- Probenecid
- Zidovudine
โน๏ธ Minor Interactions
- Metoclopramide
- Domperidone
- Cholestyramine
๐ฝ๏ธ Food Interactions
Food may delay absorption but not significantly affect extent.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity (paracetamol) and CNS depression.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, acute porphyria, concomitant use with other hepatotoxic drugs.
๐ Monitoring Parameters
Liver function tests, renal function, CBC, ECG (if high dose flupirtine).
๐คฑ Lactation Safety
Paracetamol excreted in small amounts; flupirtine unknown. Caution advised.
๐ Overdose Management
Acetylcysteine for paracetamol overdose; supportive care for flupirtine (monitor liver function, ECG).
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
Helpful and effective medicine as per my experience. Always consult a doctor.